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Book Details
Abstract
This issue of Clinics in Laboratory Medicine includes the following topics: Detection of cancer biomarkers by cerium oxide nanoparticles; Quantum dot-based assays for cancer biomarkers; Monoclonal antibody conjugated fluorescent magnetic nanoparticles for in vivo diagnosis of cancer; RNA quantification with gold nanoprobes for cancer diagnostics; Nanostructured silica materials for imaging in cancer; and Nanoparticle-based cancer cell sorting.
Table of Contents
| Section Title | Page | Action | Price |
|---|---|---|---|
| Front Cover | Cover | ||
| Clinics In Laboratory Medicine | i | ||
| Copyright Page | ii | ||
| Tables of Contents | v | ||
| Contributors | iii | ||
| Forthcoming Issues | vii | ||
| Preface | ix | ||
| Chapter 1. RNA Quantification with Gold Nanoprobes for Cancer Diagnostics | 1 | ||
| BACKGROUND | 1 | ||
| NANODIAGNOSTICS FOR CANCER | 4 | ||
| GOLD NANOPARTICLES FOR RNA DETECTION | 5 | ||
| GOLD NANOPARTICLES FOR RNA QUANTIFICATION—APPLICATION TO CANCER DIAGNOSTICS | 6 | ||
| SUMMARY | 7 | ||
| ACKNOWLEDGMENTS | 9 | ||
| REFERENCES | 9 | ||
| Chapter 2. Role of Nanodiagnostics in Personalized Cancer Therapy | 15 | ||
| NANODIAGNOSTIC TECHNOLOGIES RELEVANT TO CANCER | 15 | ||
| IMPACT OF NANOTECHNOLOGY-BASED IMAGING IN MANAGEMENT OF CANCER | 22 | ||
| COMBINATION OF DIAGNOSTICS AND THERAPEUTICS FOR CANCER | 25 | ||
| SUMMARY | 29 | ||
| REFERENCES | 29 | ||
| Chapter 3. Biomarkers Quantification with Antibody Arrays in Cancer Early Detection | 33 | ||
| BIOMARKERS AND THEIR USER IN COMBINATION | 33 | ||
| ANTIBODY ARRAYS | 35 | ||
| TECHNOLOGICAL OVERVIEW | 35 | ||
| SUMMARY | 42 | ||
| REFERENCES | 43 | ||
| Chapter 4. Cancer Biomarker Detection by Surface Plasmon Resonance Biosensors | 47 | ||
| APPLICATION OF SPR-BASED SENSING TECHNIQUES IN CANCER BIOMARKER DETECTION | 48 | ||
| SCREENING OF INHIBITORS OF TUMOR TARGETS BY SPR | 63 | ||
| CONCLUSIONS | 66 | ||
| REFERENCES | 68 | ||
| Chapter 5. Phosphorylcholine Self-Assembled Monolayer-Coated Quantum Dots: Real-Time Imaging of Live Animals by Cell Surface Mimetic Glyco-Nanoparticles | 73 | ||
| QDS COATED BY PHOSPHORYLCHOLINE SELF ASSEMBLED MONOLAYERS AND AMINOOXY-FUNCTIONALIZED MONOTHIOL DERIVATIVE | 75 | ||
| PCSAM-QDS AS AN IDEAL SCAFFOLD FOR MOLECULAR DISPLAY | 76 | ||
| GLYCO-PCSAM-QDS AS IDEAL GLYCOPROTEIN MODELS | 79 | ||
| GLYCO-PCSAM-QDS ARE VERSATILE TOOLS FOR REAL-TIME LIVE ANIMAL IMAGIN | 79 | ||
| GLYCOFORM-DEPENDENT TARGETING OF PCSAM-QDS | 82 | ||
| REFERENCES | 84 | ||
| Chapter 6. Gold Nanoparticle–Mediated Detection of Circulating Cancer Cells | 89 | ||
| BIOLOGY AND CLINICAL IMPORTANCE OF DETECTION OF CTCs | 90 | ||
| PHOTOACOUSTIC INTERACTIONS WITH NANOPARTICLES | 91 | ||
| MATERIALS AND METHODS | 93 | ||
| RESULTS | 96 | ||
| DISCUSSION | 97 | ||
| SUMMARY | 100 | ||
| REFERENCES | 100 | ||
| Index | 103 |