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Book Details
Abstract
This issue discusses the diagnosis and treatment of major depressive disorder (MDD) and other depressive disorders, with an emphasis on the psychosocial aspects of depression: how it affects societies, how it is affected by culture, and what the true meaning of recovery is for those suffering from MDD. The issue is divided into three section: Etiology, Diagnosis and Treatment. Authors address the evidence where biology and subjectivity meet. They discuss what is adaptive and what is pathologic and discuss population-based solutions that take into account the specificity of the individual. Authors also take into account combination treatments of psychotherapy and pharmacotherapy and weigh the treatment choices against specific patient subtypes.
Table of Contents
| Section Title | Page | Action | Price |
|---|---|---|---|
| Front Cover | Cover | ||
| Depression | i | ||
| Copyright Page | ii | ||
| Table of Contents | vii | ||
| Contributors | iii | ||
| Preface: Integrative Approaches to Depression and Its Treatment | xiii | ||
| Chapter 1. The Costs of Depression | 1 | ||
| BASIC DESCRIPTIVE EPIDEMIOLOGY | 1 | ||
| COURSE OF ILLNESS | 2 | ||
| THE COSTS OF MAJOR DEPRESSION | 3 | ||
| SUMMARY | 7 | ||
| DISCLOSURE | 7 | ||
| REFERENCES | 8 | ||
| Chapter 2. Depression in Cultural\rContext: “Chinese Somatization,” Revisited | 15 | ||
| CULTURE, DEPRESSION, AND SYMPTOM PRESENTATION | 17 | ||
| CHINESE SOMATIZATION | 17 | ||
| DEPRESSION AND THE CULTURE–MIND–BRAIN | 22 | ||
| ATTENTION TO SYMPTOMS IN THE CULTURE–MIND–BRAIN | 25 | ||
| BROADER IMPLICATIONS FOR RESEARCH AND TREATMENT | 28 | ||
| SUMMARY | 30 | ||
| REFERENCES | 30 | ||
| Chapter 3. Recovery from Depression | 37 | ||
| DEFINITIONS AND IMPLICATIONS | 38 | ||
| WHY DOES RECOVERY MATTER? | 40 | ||
| CHALLENGES TO THE ACHIEVEMENT OF RECOVERY | 41 | ||
| CHANGING TREATMENT EXPECTATIONS, APPROACHES, AND OUTCOMES | 44 | ||
| DIRECTIONS FOR FUTURE RESEARCH | 46 | ||
| SUMMARY | 47 | ||
| REFERENCES | 48 | ||
| Chapter 4. Etiology of Depression: Genetic and Environmental Factors | 51 | ||
| PATHOPHYSIOLOGY OF DEPRESSION | 52 | ||
| THE NEUROANATOMY OF DEPRESSION | 54 | ||
| STRESS, INFLAMMATION, AND THE NEUROENDOCRINE SYSTEM | 55 | ||
| GENES AND ENVIRONMENTAL INFLUENCES IN THE DEVELOPMENT OFDEPRESSION | 59 | ||
| EPIGENETICS | 62 | ||
| IMPLICATIONS FOR PREVENTION AND TREATMENT | 63 | ||
| TREATMENT APPROACHES FOR INDIVIDUALS WITH EARLY LIFE TRAUMA AND DEPRESSION | 64 | ||
| SUMMARY | 66 | ||
| REFERENCES | 67 | ||
| Chapter 5. The Varieties of Depressive Experience: Diagnosing Mood Disorders | 73 | ||
| HETEROGENEITY OF DEPRESSION | 74 | ||
| MISUNDERSTANDING OF PSYCHOPATHOLOGY | 79 | ||
| MODELS OF DEPRESSION | 81 | ||
| SUMMARY | 84 | ||
| REFERENCES | 84 | ||
| Chapter 6. Treatment Selection in Depression: The Role of Clinical Judgment | 87 | ||
| PATIENT EVALUATION OVERVIEW | 88 | ||
| ACUTE PHASE | 91 | ||
| PREVENTION OF RECURRENCE | 93 | ||
| CLINICAL JUDGMENT | 95 | ||
| SUMMARY | 95 | ||
| REFERENCES | 96 | ||
| Chapter 7. Cognitive Behavioral Therapy for Depression | 99 | ||
| EVIDENCE FOR THE USE OF CBT FOR MAJOR DEPRESSION | 99 | ||
| EVIDENCE FOR THE USE OF CBT COMBINED WITH MEDICATION FOR MAJOR DEPRESSION | 100 | ||
| THEORETICAL BASIS SUPPORTING CBT FOR DEPRESSION | 100 | ||
| CBT IN CLINICAL PRACTICE | 102 | ||
| PATIENT SELECTION | 106 | ||
| SUMMARY | 107 | ||
| REFERENCES | 107 | ||
| Chapter 8. Psychodynamic Treatment of Depression | 111 | ||
| SPECIFICITY OF THE PSYCHODYNAMIC APPROACH: COMMON AND SPECIFIC FACTORS IN PSYCHODYNAMIC TREATMENTS OF DEPRESSION | 112 | ||
| THEORETICAL PERSPECTIVES | 114 | ||
| EFFICACY AND EFFECTIVENESS OF PSYCHODYNAMIC THERAPY FOR DEPRESSION | 117 | ||
| PROCESS AND OUTCOME OF PSYCHODYNAMIC TREATMENT | 120 | ||
| ACCEPTABILITY AND SUITABILITY OF PSYCHODYNAMIC TREATMENT | 122 | ||
| SUMMARY | 122 | ||
| ACKNOWLEDGMENTS | 123 | ||
| REFERENCES | 123 | ||
| Chapter 9. Evidence-Based Somatic Treatment of Depression in Adults | 131 | ||
| EFFICACY STUDIES OF ANTIDEPRESSANTS: ARE ANTIDEPRESSANTS SIMPLY PLACEBOS WITH SIDE EFFECTS? | 132 | ||
| EFFECTIVENESS STUDIES OF ANTIDEPRESSANTS: THE STAR*D TRIALS | 135 | ||
| SUMMARY | 141 | ||
| REFERENCES | 141 | ||
| Chapter 10. How (Not What) to Prescribe: Nonpharmacologic Aspects of Psychopharmacology | 143 | ||
| THE PROBLEM OF TREATMENT RESISTANCE | 144 | ||
| THE MEANING OF MEDICATION | 144 | ||
| AVOID A MIND-BODY SPLIT | 145 | ||
| KNOW WHO THE PATIENT IS | 147 | ||
| CULTIVATE THE PHARMACOTHERAPEUTIC ALLIANCE | 150 | ||
| ATTEND TO THE PATIENT’S AMBIVALENCE | 153 | ||
| ADDRESS COUNTERTHERAPEUTIC USES OF MEDICATIONS | 156 | ||
| IDENTIFY AND CONTAIN COUNTERTRANSFERENCE PRESCRIBING | 157 | ||
| SUMMARY | 158 | ||
| REFERENCES | 159 | ||
| Chapter 11. Combined Treatment of Depression | 165 | ||
| THE BIOPSYCHOSOCIAL MODEL IN CONSIDERING COMBINED TREATMENTS | 167 | ||
| RESEARCH ON COMBINED TREATMENTS | 167 | ||
| DISCUSSION | 174 | ||
| REFERENCES | 176 | ||
| Chapter 12. Child and Adolescent Depression: Psychotherapeutic, Ethical, and Related Nonpharmacologic Considerations for General Psychiatrists and Others Who Prescribe | 181 | ||
| ADULT PSYCHIATRISTS CARING FOR CHILDREN AND ADOLESCENTS: GENERAL CONSIDERATIONS | 182 | ||
| WHO REFERS DEPRESSED CHILDREN AND ADOLESCENTS TO GENERAL PSYCHIATRISTS AND COLLABORATES IN CONTINUED CARE? | 184 | ||
| SCHOOLS AND THE GENERAL PSYCHIATRIST | 185 | ||
| CHILD AND ADOLESCENT DEPRESSION AND COMMON PSYCHOTHERAPIES | 187 | ||
| PRESCRIBING FOR CHILDREN AND ADOLESCENTS: THE PSYCHODYNAMICS OF PSYCHOPHARMACOLOGY | 189 | ||
| ETHICAL ASPECTS OF CHILD AND ADOLESCENT PHARMACOTHERAPY | 191 | ||
| BLACK BOX WARNINGS AND OFF-LABEL PRESCRIBING | 194 | ||
| SUMMARY | 195 | ||
| ACKNOWLEDGMENTS | 196 | ||
| REFERENCES | 196 | ||
| Chapter 13. Depression in Later Life: An Overview with Treatment Recommendations | 203 | ||
| CHARACTERIZING LATE-LIFE DEPRESSION | 204 | ||
| DIFFERENTIAL DIAGNOSIS | 205 | ||
| TREATMENT OF DEPRESSION IN LATER LIFE | 208 | ||
| RELATIONSHIP OF COGNITIVE IMPAIRMENT TO LATE-LIFE DEPRESSION | 218 | ||
| LOCUS OF CARE | 221 | ||
| SUMMARY | 222 | ||
| REFERENCES | 222 | ||
| Chapter 14. Depression in Medically Ill Patients | 231 | ||
| UNIQUE CHALLENGES IN ASSESSING DEPRESSION IN MEDICALLY ILL PATIENTS | 231 | ||
| “DEPRESSION” AS A RESULT OF THE PSYCHOLOGICAL IMPACT OF ILLNESS | 232 | ||
| “DEPRESSION” AS A RESULT OF THE PHYSIOLOGIC IMPACT OF ILLNESS OR TREATMENT | 233 | ||
| DEPRESSION AS A CAUSE OF MEDICAL ILLNESS | 234 | ||
| MASKED PRESENTATIONS OF DEPRESSION | 235 | ||
| WHEN “DEPRESSION” IS NOT DEPRESSION AT ALL | 235 | ||
| MIXED PICTURES | 236 | ||
| SPECIAL CONSIDERATIONS WHEN TREATING DEPRESSION IN MEDICALLY ILL PATIENTS | 236 | ||
| SUMMARY | 243 | ||
| REFERENCES | 243 | ||
| Chapter 15. Management of Treatment-Resistant Depression | 249 | ||
| BURDEN/IMPACT OF TRD | 250 | ||
| COURSE | 250 | ||
| RISK FACTORS | 251 | ||
| ASSESSMENT OF TRD | 251 | ||
| PHARMACOLOGIC TREATMENT OPTIONS | 252 | ||
| NONPHARMACOLOGIC TREATMENTS FOR TRD | 254 | ||
| PSYCHOTHERAPY FOR TRD | 254 | ||
| FAMILY THERAPY FOR TRD | 255 | ||
| DISEASE MANAGEMENT | 256 | ||
| SUMMARY | 259 | ||
| REFERENCES | 260 | ||
| Index | 267 |