Menu Expand
Autism Spectrum Disorders: Practical Overview For Pediatricians,  An Issue of Pediatric Clinics - E-Book

Autism Spectrum Disorders: Practical Overview For Pediatricians, An Issue of Pediatric Clinics - E-Book

Dilip R Patel | Donald E. Greydanus

(2012)

Additional Information

Book Details

Abstract

The Guest Editors have assembled expert authors to cover the full clinical span of the topic autism and autism spectrum disorders. An historical perspective of the evolution of the disorder opens the issue. Next, comprehensive coverage is given to an article on the definitions, diagnostic criteria, and clinical features of autism spectrum disorders. Other articles in the issue cover the relevant topics like epidemiology, genetic syndromes and genetic testing, early diagnosis and diagnostic evaluation, and neuroimaging and neurochemistry of autism. Authors also present information on tsocial skills for the autistic child, behavioral interventions, and transitioning the autistic child into adulthood, to name a few. This issue should be very well received by pediatricians.

Table of Contents

Section Title Page Action Price
Front Cover Cover
Pediatric Clinics of North America i
Copyright Page ii
Table of Contents ix
Contributors v
Foreword: Autism Spectrum Disorders: Practical Overview for Pediatricians xv
Preface: Autism Spectrum Disorders: Practical Overview for Pediatricians xix
Chapter 1. Historical Perspectives on Autism: Its Past Record of Discovery and Its Present State of Solipsism, \rSkepticism, and Sorrowful Suspicion 1
ALFRED RUSSEL WALLACE 3
PAUL EUGEN BLEULER 3
LEO KANNER 4
HANS ASPERGER 4
BRUNO BETTELHEIM 5
BERNARD RIMLAND 5
OLE IVAR LØVAAS 6
ANDREW WAKEFIELD 6
PAUL OFFIT 6
AUTISM IN THE INTERNET AGE 6
SUMMARY 7
REFERENCES 8
Chapter 2. In the Doctor’s Office: A Parent Perspective 13
RED UDDER 13
NICK'S STORY 15
I WILL NOT BE DEAF 17
Chapter 3. Autism Spectrum Disorders: Clinical Features and Diagnosis 19
DSM IV AND ICD 10 CRITERIA 19
PROPOSED DSM V CRITERIA 20
DIAGNOSTIC CRITERIA AND PREVALENCE 21
ASD IN PRIMARY CARE 21
SYMPTOMS OF AUTISM 21
ASSOCIATION WITH INTELLECTUAL DISABILITY 22
ASSOCIATION WITH EPILEPSY 22
MENTAL STATUS EXAMINATION 23
PHYSICAL EXAMINATION 23
SCREENING AND SCREENING INSTRUMENTS 23
DIFFERENTIAL DIAGNOSIS AND COMORBIDITY 24
SUMMARY 24
REFERENCES 24
Chapter 4. Epidemiology of Autism Spectrum Disorders 27
INCIDENCE 27
PREVALENCE OF AUTISM IN THE UNITED STATES 28
PREVALENCE OF AUTISM GLOBALLY 28
PREVALENCE OF AUTISM IN ASIA 28
PREVALENCE OF AUTISM IN EUROPE 29
CHANGE IN PREVALENCE SINCE 1940 29
CONDITIONS ASSOCIATED WITH AUTISM 31
RISK FACTORS FOR AUTISM 32
ANATOMIC TRAITS WITH AUTISM 35
GENETIC SYNDROMES ASSOCIATED WITH AUTISM 35
PROGNOSIS 35
MORBIDITIES 36
MORTALITIES 37
SUMMARY 38
REFERENCES 38
Chapter 5. Neurobiological Basis of Autism 45
DIAGNOSTIC ISSUES 45
THE BRAIN IN AUTISM 46
EPILEPSY AND AUTISM 48
AUTISTIC/LANGUAGE REGRESSION AND EPILEPSY 50
SLEEP PROBLEMS ASSOCIATED WITH AUTISM 51
SENSORY ISSUES ASSOCIATED WITH AUTISM 52
MOTOR ISSUES ASSOCIATED WITH AUTISM 54
SUMMARY 56
REFERENCES 56
Chapter 6. Neuroimaging and Neurochemistry of Autism 63
PET AND SPECT METHODOLOGY 64
STUDIES OF NEUROTRANSMITTER FUNCTION WITH PET AND SPECT IN AUTISM 65
DOPAMINE PRECURSOR AND TRANSPORTER STUDIES 65
SEROTONIN PRECURSOR, TRANSPORTER, AND RECEPTOR STUDIES 66
GABAA RECEPTOR BINDING STUDIES 67
MRS METHODOLOGY 68
NAA STUDIES IN AUTISM 68
GLUTAMATE/GLUTAMINE IN AUTISM 69
SUMMARY AND FUTURE DIRECTIONS 70
REFERENCES 70
Chapter 7. Role of Endocrine Factors in Autistic Spectrum Disorders 75
GROWTH HORMONE AND RELATED FACTORS 77
OXYTOCIN 77
VASOPRESSIN 78
APELIN 79
MELATONIN 79
THYROID HORMONE 80
CORTISONE 80
TESTOSTERONE 81
ESTROGEN 82
SECRETIN 82
NEUROTENSIN 82
VITAMIN D 83
DIABETES MELLITUS AND AUTOIMMUNE DISORDERS 83
ENDOCRINE DISRUPTORS 84
SUMMARY 84
REFERENCES 84
Chapter 8. Office Screening and Early Identification of Children with Autism 89
WHAT IS A PEDIATRICIAN TO DO? 91
HOW EARLY IS EARLY SCREENING? 93
SOME PRACTICAL SUGGESTIONS FOR AUTISM SCREENING 94
WHAT TO DO AFTER A POSITIVE SCREEN 96
SCREENING IS REIMBURSABLE 97
AUTISM SCREENING AND ELECTRONIC HEALTH RECORDS 98
SUMMARY 99
REFERENCES 100
Chapter 9. Diagnostic Evaluation of Autism Spectrum Disorders 103
CHALLENGES IN ASD DIAGNOSTIC ASSESSMENT 104
BEST PRACTICES IN ASD DIAGNOSTIC EVALUATIONS 105
THE IMPORTANCE OF DIAGNOSTIC EVALUATIONS 108
SUMMARY 108
ACKNOWLEDGMENTS 109
REFERENCES 109
Chapter 10. Approach to the Genetic Evaluation of the Child with Autism 113
METABOLIC DISORDERS 116
MITOCHONDRIAL DISORDERS 119
CHROMOSOME ANOMALIES 119
MONOGENIC DISORDERS 120
REFERENCES 124
Chapter 11. Language and Communication in Autism: An Integrated View 129
INTEGRATED VIEW OF COMMUNICATION, LANGUAGE, AND AUTISM 130
INTEGRATED VIEW OF IDENTIFICATION AND ASSESSMENT 133
INTEGRATED VIEW OF HOW TO SUPPORT FAMILIES IN PROMOTING THEIR CHILDREN’S COMMUNICATION DEVELOPMENT 134
INTEGRATED VIEW OF INTERVENTION APPROACHES FOR LANGUAGE, LITERACY, AND COMMUNICATION 135
SUMMARY 139
REFERENCES 139
Chapter 12. Behavioral Interventions for Children with Autism Spectrum Disorders 147
BEHAVIORAL TREATMENT 148
EIBI 149
PROBLEM-FOCUSED OUTPATIENT AND CONSULTATIVE SERVICES 152
COLLABORATION AND COORDINATION WITH BEHAVIORAL TREATMENT PROVIDERS 155
SUMMARY 155
REFERENCES 156
APPENDIX 1: COMMON TERMS USED IN BEHAVIORAL TREATMENT OF ASDs 162
APPENDIX 2: FREQUENTLY ASKED QUESTIONS ABOUT BEHAVIOR TREATMENT OF ASD AND RESOURCES FOR FAMILIES 163
BEHAVIORAL TREATMENT RESOURCES FOR FAMILIES 164
Chapter 13. Social Skills Training for Children with Autism 165
SOCIAL SKILLS DEFICITS IN ASD 165
SOCIAL SKILLS INTERVENTIONS 166
ACCESS TO SERVICES 171
FUTURE DIRECTIONS 171
SUMMARY, CLINICAL IMPLICATIONS, AND RECOMMENDATIONS FOR PEDIATRICIANS 172
REFERENCES 172
Chapter 14. Psychopharmacology of Autism Spectrum Disorders 175
TOOLS USED TO MEASURE OUTCOMES 176
TREATMENT OF ASD-ASSOCIATED/COMORBID SYMPTOMS 177
SUMMARY 183
ACKNOWLEDGMENTS 184
REFERENCES 184
Chapter 15. Transition from School to Work for Students with Autism Spectrum Disorders: Understanding the Process and Achieving Better Outcomes 189
THE CHARACTERISTICS OF ASD IN ADOLESCENCE AND EARLY ADULTHOOD 190
TRANSITION NEEDS FOR YOUTH WITH ASD 193
TRANSITION OUTCOMES 193
FACTORS ASSOCIATED WITH FAVORABLE TRANSITION OUTCOMES 194
EMPLOYMENT MODELS FOR INDIVIDUALS WITH ASD 196
IMPLICATIONS FOR HEALTH PROFESSIONALS 199
REFERENCES 199
Chapter 16. Sensory Processing in Children with Autism Spectrum Disorders and Impact on Functioning 203
SPD DEFINED 203
PHYSIOLOGIC EVIDENCE FOR DISTINCTION OF SENSORY MODULATION DISORDERS 206
IMPACT OF SENSORY MODULATION DISORDERS ON FUNCTIONING FOR CHILDREN WITH ASD 207
WHEN TO REFER 209
TREATMENT AND OUTCOMES 209
SUMMARY 211
REFERENCES 212
Index 215