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Gastrointestinal Issues in Critical Care, An Issue of Critical Care Clinics, E-Book

Gastrointestinal Issues in Critical Care, An Issue of Critical Care Clinics, E-Book

Rahul S. Nanchal | Ram M. Subramanian

(2016)

Additional Information

Abstract

This issue of Critical Care Clinics focuses on Gastrointestinal Critical Care. Articles include: Non variceal Upper Gastrointestinal bleeds; Lower Gastrointestinal bleeds; Mesenteric Ischemia; Peritonitis; The open abdomen and intra abdominal infections; Gut motility issues in critical illness; Gut as the motor of multiple organ dysfunction; Intra abdominal hypertension and abdominal compartment syndrome; Abdominal circulatory interactions in critical illness; Severe acute pancreatitis and necrotizing pancreatitis; and Nutrition in the critically ill.

Table of Contents

Section Title Page Action Price
Front Cover Cover
Gastrointestinal Issues in \rCritical Care i
Copyright \r ii
Contributors iii
CONSULTING EDITOR iii
EDITORS iii
AUTHORS iii
Contents vii
Preface: Gastrointestinal Issues in Critical Care\r vii
Mesenteric Ischemia\r vii
Controversies in Critical Care Nutrition Support\r vii
Gut Motility Issues in Critical Illness\r vii
The Gut as the Motor of Multiple Organ Dysfunction in Critical Illness\r vii
Abdominal Compartment Hypertension and Abdominal Compartment Syndrome\r viii
Nonvariceal Upper Gastrointestinal Bleeding\r viii
Lower Gastrointestinal Hemorrhage\r viii
Role of the Open Abdomen in Critically Ill Patients\r ix
Abdominal Circulatory Interactions\r ix
Severe Acute Pancreatitis and Necrotizing Pancreatitis\r ix
CRITICAL CARE CLINICS\r x
FORTHCOMING ISSUES x
July 2016 x
October 2016 x
January 2017 x
RECENT ISSUES x
January 2016 x
October 2015 x
July 2015 x
Preface:Gastrointestinal \rIssues in Critical Care xi
Mesenteric Ischemia 155
Key points 155
INTRODUCTION 155
EPIDEMIOLOGY AND COMORBIDITIES ASSOCIATED WITH ACUTE MESENTERIC ISCHEMIA 156
CLINICAL PRESENTATION OF ACUTE MESENTERIC ISCHEMIA 156
LABORATORY TESTS IN ACUTE MESENTERIC ISCHEMIA 156
IMAGING STUDIES IN ACUTE MESENTERIC ISCHEMIA 157
MESENTERIC ANATOMY AND PHYSIOLOGY 158
PATHOPHYSIOLOGY OF ACUTE MESENTERIC ISCHEMIA 159
INITIAL TREATMENT OF PATIENTS WITH ACUTE MESENTERIC ISCHEMIA 162
OPEN SURGICAL TREATMENT OF ACUTE MESENTERIC ISCHEMIA 162
ENDOVASCULAR TREATMENT OF ACUTE MESENTERIC ISCHEMIA 163
NONSURGICAL TREATMENT OF ACUTE MESENTERIC ISCHEMIA 163
OUTCOME IN ACUTE MESENTERIC ISCHEMIA 164
PROGNOSTIC SCORING SYSTEMS IN ACUTE MESENTERIC ISCHEMIA 164
INTENSIVE CARE MANAGEMENT OF PATIENTS WITH ACUTE MESENTERIC ISCHEMIA 166
ACUTE MESENTERIC ISCHEMIA OCCURRING IN THE INTENSIVE CARE UNIT 166
SUMMARY 167
REFERENCES 167
Controversies in Critical Care Nutrition Support 173
Key points 173
INTRODUCTION 173
PHYSIOLOGIC BASIS FOR NUTRITION SUPPORT 174
NUTRITIONAL RISK 175
LOCATION OF ENTERAL NUTRITION DELIVERY 177
EARLY VERSUS DELAYED ENTERAL NUTRITION 178
AUTOPHAGY AND PERMISSIVE UNDERFEEDING 179
Autophagy 179
Permissive Underfeeding 180
PARENTERAL NUTRITION 181
Enteral Versus Parenteral Nutrition 181
Supplemental Parenteral Nutrition 181
NUTRITION SUPPORT IN SHOCK 182
SUMMARY 186
REFERENCES 186
Gut Motility Issues in Critical Illness 191
Key points 191
INTRODUCTION 191
GUT COMPONENTS 192
SIGNS AND SYMPTOMS OF ACUTE GASTROINTESTINAL INJURY 192
GASTROINTESTINAL BLEEDING 192
ISCHEMIA-REPERFUSION INJURY 192
GASTROINTESTINAL DYSMOTILITY 193
MOTOR FUNCTION OF THE PROXIMAL GASTROINTESTINAL TRACT 194
GASTROINTESTINAL TRACT BARRIER DYSFUNCTION 194
INCREASED MORBIDITY AND MORTALITY WITH ACUTE GASTROINTESTINAL INJURY 195
Nutritional Deficits 195
Gastrointestinal Tract–associated Infection 196
Aspiration of Enteral Feeding 196
The Gut Hypothesis of Sepsis 196
STANDARDIZING DEFINITIONS/TREATMENT RECOMMENDATIONS 196
SUMMARY 198
REFERENCES 198
The Gut as the Motor of Multiple Organ Dysfunction in Critical Illness 203
Key points 203
OVERVIEW 203
THE GUT IN HEALTH 204
Epithelium 204
Immune System 204
Microbiome 204
PRECLINICAL INSIGHTS INTO THE ROLE OF THE GUT AS THE MOTOR OF MULTIPLE ORGAN DYSFUNCTION SYNDROME 204
The Gut Lymph Hypothesis 204
Apoptosis 205
Hyperpermeability 205
Altering the Microbiome 206
GUT FAILURE IN CRITICALLY ILL PATIENTS 207
Clinical Diagnosis of Gut Failure 207
TARGETING THE MICROBIOME 207
Probiotics, Prebiotics, and Synbiotics 207
Selective Decontamination of the Digestive Tract 208
Fecal Transplant 208
Nutrition 209
REFERENCES 209
Abdominal Compartment Hypertension and Abdominal Compartment Syndrome 213
Key points 213
INTRODUCTION 213
DEFINITION AND CAUSES OF INTRA-ABDOMINAL HYPERTENSION/ABDOMINAL COMPARTMENT SYNDROME 214
DIAGNOSIS: PHYSIOLOGIC MARKERS OF ABDOMINAL COMPARTMENT SYNDROME 215
DIAGNOSIS: MEASUREMENT OF ABDOMINAL PRESSURE 217
TREATMENT 218
SUMMARY 219
REFERENCES 220
Nonvariceal Upper Gastrointestinal Bleeding 223
Key points 223
INTRODUCTION 223
EPIDEMIOLOGY 224
PATIENT EVALUATION OVERVIEW 224
Approach to the Upper Gastrointestinal Bleed 224
Risk Stratification 225
Differential Diagnosis 225
Treatment 225
Emergent evaluation and resuscitation 225
Goals of resuscitation 227
Transfusion strategies 227
Correction of coagulopathy 229
Pharmacologic treatment options 231
Chronic management 232
Nonpharmacologic treatment options 232
Disease-specific treatment options 233
Infection 233
Malformation 235
Malignancy 235
Mechanical 235
Iatrogenic 236
Peptic ulcer disease 236
Special consideration 236
FUTURE DIRECTION 236
REFERENCES 237
Lower Gastrointestinal Hemorrhage 241
Key points 241
DEFINITION 242
EPIDEMIOLOGY 242
CRITERIA FOR SEVERITY AND RISK STRATIFICATION 242
ETIOLOGIES 243
CLINICAL PRESENTATION 243
INITIAL MANAGEMENT 244
RESUSCITATION STRATEGIES 244
COLONOSCOPY 245
COMMON ETIOLOGIES 247
Diverticular Bleeding 247
Angiodysplasia 248
OTHER MODALITIES OF DIAGNOSIS AND THERAPY 248
Radionuclide Studies 248
Angiography Therapy 249
Surgical Therapy 249
OTHER ETIOLOGIES OF LOWER GASTROINTESTINAL BLEEDING 249
Postpolypectomy Bleeding 249
Ischemic Colitis 250
Dieulafoy Lesion 250
Obscure Bleeding 250
SUMMARY 251
REFERENCES 252
Role of the Open Abdomen in Critically Ill Patients 255
Key points 255
ABDOMINAL COMPARTMENT SYNDROME 256
DIAGNOSIS OF ABDOMINAL COMPARTMENT SYNDROME 256
MANAGEMENT OF THE OPEN ABDOMEN 257
CAUSES OF ABDOMINAL COMPARTMENT SYNDROME 257
COMPLICATIONS OF THE OPEN ABDOMEN TECHNIQUE 258
EARLY COMPLICATIONS 259
Wound Management 259
Surgical Site Infections 259
Intra-Abdominal Infection 259
Gastrointestinal Fistula 260
LATE COMPLICATIONS 260
Ventral Hernia 260
SUMMARY 261
REFERENCES 261
Abdominal Circulatory Interactions 265
Key points 265
RELATIONSHIP BETWEEN RIGHT ATRIAL PRESSURE, ABDOMINAL PRESSURE, AND VENOUS RETURN 266
RELATIONSHIP BETWEEN VENTRICULAR FUNCTION AND ABDOMINAL PRESSURE 269
CLINICAL APPLICATIONS 270
Prone Positioning 270
Ascites 272
Laparoscopic Surgery 272
Weaning from Mechanical Ventilation 273
SUMMARY 274
REFERENCES 274
Severe Acute Pancreatitis and Necrotizing Pancreatitis 279
Key points 279
INTRODUCTION 279
Severe Acute Pancreatitis 279
PATIENT EVALUATION OVERVIEW 283
Clinical Features 283
History 283
Physical examination 283
PHARMACOLOGIC TREATMENT OPTIONS 284
Management 284
Fluid Resuscitation 286
Respiratory Care 286
Cardiovascular Care 286
Metabolic Complications 286
Infectious Disease and Antibiotics 287
NONPHARMACOLOGIC TREATMENT OPTIONS 287
Endoscopy 287
Nutrition 287
RADIOLOGIC AND SURGICAL TREATMENT OPTIONS 288
EVALUATION OF OUTCOME AND LONG-TERM RECOMMENDATIONS 288
SUMMARY 289
REFERENCES 289
Index 291