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Health Care-Associated Transmission of Hepatitis B and C Viruses, An Issue of Clinics in Liver Disease - E-Book

Health Care-Associated Transmission of Hepatitis B and C Viruses, An Issue of Clinics in Liver Disease - E-Book

Bandar Al Knawy

(2010)

Additional Information

Book Details

Abstract

This issue offers the latest information regarding the transmission of hepatitis viruses in various healthcare settings. It delves with a very timely and interesting patient safety subject that specifically targets healthcare professionals, gastroenterologists, hepatologists, oncologists, dentists and all healthcare workers to adopt and share a variety of best practices to prevent this adverse event. Well known faculty in liver disease, infection control as well as a medical practice in a legal setting have been assembled to produce a comprehensive and concise edition that highlights the latest information regarding hepatitis B and C transmission in healthcare. It aims to provide an overview on the molecular epidemiology, the outbreak reports, the transmission in hemodialysis, endoscopy, dental, oncology, management, legal aspects and the infection prevention measures to reduce the risk of needless exposure of patients to these blood borne pathogens.

Table of Contents

Section Title Page Action Price
Front Cover Cover
Contents vii
Preface xiii
Chapter 1. Epidemiology of Hepatitis B and C Viruses: A Global Overview 1
HEPATITIS B 1
HEPATITIS C 9
SUMMARY 15
REFERENCES 15
Chapter 2. Occupational Exposure of Health Care Personnel to Hepatitis B and Hepatitis C: Prevention and Surveillance Strategies 23
RISK OF HEPATITIS B AND HEPATITIS C VIRUS EXPOSURES IN HEALTH CARE PERSONNEL 24
PROTECTING HEALTH CARE PERSONNEL FROM EXPOSURE TO BLOOD AND BODY FLUIDS 26
MEASURES TO PREVENT HEPATITIS B OR HEPATITIS C INFECTION AFTER AN EXPOSURE 29
SURVEILLANCE 30
SUMMARY 31
REFERENCES 31
Chapter 3. Molecular Epidemiology of Health Care– Associated Transmission of Hepatitis B and C Viruses 37
PROBLEMS AND OBSTACLES IN INVESTIGATING HEPATITIS B VIRUS OR HEPATITIS C VIRUS IN THE HEALTH CARE SETTING 38
TECHNIQUES OF MOLECULAR EPIDEMIOLOGY OF HEPATITIS C AND B 40
HEPATITIS C IN HEALTH CARE SETTINGS 42
HEPATITIS B IN HEALTH CARE SETTINGS 45
THE FUTURE OF HEPATITIS MOLECULAR EPIDEMIOLOGY 45
REFERENCES 46
Chapter 4. Health Care– Associated Transmission of Hepatitis B and C Viruses in Hemodialysis Units 49
HBV 49
INFECTION CONTROL PROCEDURES AGAINST HBV IN DIALYSIS UNITS 50
NATURAL HISTORY OF HBV INFECTION IN DIALYSIS PATIENTS 50
HBV-RELATED LIVER DISEASE IN DIALYSIS: BIOCHEMICAL EVIDENCE 51
THERAPY OF HEPATITIS B IN DIALYSIS PATIENTS 52
HCV: EPIDEMIOLOGY 52
NOSOCOMIAL TRANSMISSION OF HCV IN DIALYSIS 53
MODES OF NOSOCOMIAL TRANSMISSION OF HCV IN DIALYSIS UNITS 53
NATURAL HISTORY OF HCV INFECTION IN DIALYSIS UNITS 54
THERAPY OF HEPATITIS C IN DIALYSIS POPULATION 54
COMBINATION THERAPY FOR HEPATITIS C IN DIALYSIS 55
SUMMARY 56
REFERENCES 56
Chapter 5. Health Care–Associated Transmission of Hepatitis B and C Viruses in Endoscopy Units 61
TRANSMISSION OF HEPATITIS C DURING GASTROINTESTINAL ENDOSCOPY 62
TRANSMISSION OF HEPATITIS B DURING GASTROINTESTINAL ENDOSCOPY 64
TRANSMISSION OF HEPATITIS C AND HEPATITIS B BETWEEN ENDOSCOPY PERSONNEL AND PATIENTS 65
PREVENTION OF THE TRANSMISSION OF HEPATITIS C AND HEPATITIS B DURING GASTROINTESTINAL ENDOSCOPY 65
REFERENCES 66
Chatper 6. Health Care–Associated Transmission of Hepatitis B and C in Oncology Care 69
HEPATITIS B TRANSMISSION RELATED TO BLOOD PRODUCT ADMINISTRATION 69
HEPATITIS C TRANSMISSION RELATED TO BLOOD PRODUCT ADMINISTRATION 70
TRANSMISSION OF HEPATITIS B AND C RELATED TO BREACHES IN INFECTION CONTROL 71
SUMMARY 72
REFERENCES 72
Chapter 7. Management of Acute Hepatitis B 75
INCIDENCE AND RISK FACTORS ASSOCIATED WITH ACUTE HBV 76
THE CLINICAL SEQUENCE OF ACUTE HBV INFECTION 77
SEROLOGIC MARKERS OF HBV INFECTION 79
IMMUNE MECHANISMS INVOLVED IN RESOLUTION OF ACUTE HBV 80
VARIANTS OF ACUTE HBV INFECTION 81
EXACERBATIONS IN CHRONIC HBV MIMICKING ACUTE INFECTION 82
TREATMENT OF ACUTE HBV 84
REFERENCES 86
Chapter 8. Health Care–Associated Transmission of Hepatitis B & C Viruses in Dental Care (Dentistry) 93
HEPATITIS B EPIDEMIOLOGY 93
CLINICAL FEATURES AND NATURAL HISTORY OF HBV INFECTION 94
HEPATITIS B AND THE DENTAL CARE SETTING 95
HEPATITIS C EPIDEMIOLOGY 96
CLINICAL FEATURES AND NATURAL HISTORY OF HCV INFECTION 97
HEPATITIS C AND DENTAL CARE SETTING 97
OCCUPATIONAL EXPOSURES TO HBV AND HCV IN DENTISTRY 98
POSTEXPOSURE PROPHYLAXIS 98
SUMMARY 99
REFERENCES 100
Chapter 9. Health Care–Associated Hepatitis B and C Viruses: Legal Aspects 105
OVERVIEW OF SOURCES OF LAW 106
LEGAL STANDARDS RELATING TO THE PREVENTION OF TRANSMISSION 106
LIABILITY ASSOCIATED WITH EXPOSURE AND TRANSMISSION 111
FUTURE LEGAL CONSIDERATIONS 114
REFERENCES 114
Chapter 10. Infection Control Guidelines for Prevention of Health Care–Associated Transmission of Hepatitis B and C Viruses 119
OVERVIEW OF HEALTH CARE–ASSOCIATED TRANSMISSION OF HEPATITIS B AND HEPATITIS C 119
ADDITIONAL CHALLENGES 127
REFERENCES 128
Chapter 11. US Outbreak Investigations Highlight the Need for Safe Injection Practices and Basic Infection Control 137
OUTBREAKS: RECENT UNITED STATES EXPERIENCE 138
SYRINGE REUSE 138
CONTAMINATION OF EQUIPMENT, SUPPLIES, AND THE ENVIRONMENT 143
THE CLINICIAN’S ROLE IN IDENTIFYING HEALTH CARE–ASSOCIATED INFECTIONS 145
PREVENTING HEALTH CARE–ASSOCIATED BLOODBORNE VIRUS INFECTIONS 145
SUMMARY 147
REFERENCES 147
Chapter 12. Health Care Workers as Source of Hepatitis B and C Virus Transmission 153
HEALTH CARE WORKER–TO–PATIENT TRANSMISSION OF HEPATITIS B 154
HEALTH CARE WORKER–TO–PATIENT TRANSMISSION OF HEPATITIS C 156
PRACTICES TO PREVENT TRANSMISSION OF BLOOD-BORNE PATHOGENS FROM INFECTED HEALTH CARE WORKERS 158
MANAGEMENT OF INFECTED HEALTH CARE WORKERS 158
SUMMARY 164
REFERENCES 164
Chapter 13. Management of Acute Hepatitis C 169
DIAGNOSIS OF ACUTE HCV INFECTION 169
TREATMENT OF ACUTE HCV INFECTION 170
OPTIMAL TIMING OF TREATMENT 171
DURATION OF TREATMENT 172
OPTIMAL TREATMENT REGIMEN 173
TREATMENT OF HIV–CO-INFECTED OR HEMODIALYSIS PATIENTS 173
SUMMARY 175
REFERENCES 175
Index 177