Abstract

Pharmacogenomics: Challenges and Opportunities in Therapeutic Implementation includes discussions and viewpoints from the academic, regulatory, pharmaceutical, clinical, socio-ethical and economic perspectives. Each chapter presents an overview of the potential or opportunity within the areas discussed and also outlines foreseeable challenges and limitations in moving pharmacogenomics into drug development and direct therapeutic applications. This edited book contains review questions for a more in-depth analysis of the implications of pharmacogenomics and discussion points to generate ideas on best to move the field forward. Clinical pearls and case studies are used to illustrate real-life experiences and both successful and unsuccessful applications. Tables, figures, and annotations are included throughout the book to facilitate understanding and further reference.

• Multi-contributed book and chapters are written by contributors who are experts in their field
• Provides perspectives from those involved in all aspects of pharmacogenomics—including academic, regulatory, economic, industry and medical—to illustrate how all of the pieces fit together and where the challenges may be
• Includes case studies of both successful and unsuccessful applications so readers can consider the potential and challenges in moving the science into drug development and direct therapeutic applications
• Chapters contain discussion questions and clinical pearls and enable readers to reflect on how to move pharmacogenomics forward and apply these observations and useful tips to their own work and research

"...a practical and indispensable resource on both the opportunities and challenges that allows readers to reflect on the future direction of pharmacogenomics while applying these observations to their own work or research."--Anticancer Research, February 2015

"Lam and Cavallari bring together pharmacy and other specialists from North America, Europe, and Asia for 13 chapters aimed at scientists, clinicians, and students in health and pharmaceutical sciences. The chapters consider the translation of pharmacogenomic findings into therapeutic applications from academic, regulatory, pharmaceutical, clinical, socioethical, and economic perspectives."--Reference and Research Book News, August 2013

"This book succeeds in providing a relevant and unique perspective, by international experts in the field, on the progress and challenges facing the translation of pharmacogenomics into clinical practice. I highly recommended it to anyone with an interest in the topic, from the essential basics to its role in the future practice of medicine."--Doody.com, August 2, 2013

"…this latest state-of-the-art book on pharmacogenomics successfully tackles the objectives described by its title. The key feature of the book is the in-depth discussion on a range of challenges currently facing pharmacogenomics in the widely publicised revolution in drug therapy… the Editors and the contributors are to be congratulated for their offering and this excellent book should serve well the needs of all those interested in the potential role of pharmacogenomic revolution in personalizing therapy…" – British Journal of Clinical Pharmacology, November 5, 2013