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Handbook of Mucosal Immunology

Handbook of Mucosal Immunology

Pearay L. Ogra | Jiri Mestecky | Michael E. Lamm | Warren Strober | Jerry R. McGhee | John Bienenstock


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Researchers have recently made tremendous progress in the area of mucosal immunology, greatly increasing our understanding of the common mucosal immune system, mucosal infections, and oral immunization. However, thisresearch has not previously been made available in a single work. In its large 81/2"x 11"format, Handbook of Mucosal Immunology covers the entire spectrum of mucosal immunity and is organized in two main sections to present the basic biology of the common mucosal immune system and the immune responses of the mucosae.
The first section provides an introduction and historical perspective of the mucosal immune system and includes comprehensive discussion of the development and physiology of mucosal defense. It discusses such topics as the structure and function of themucosal epithelium, characteristics of mucosal-associated lymphoid tissue (MALT), Peyers patches, and concepts of mucosal vaccines. The second section focuses on the secretory immune system with special reference to mucosal diseases in the digestive (GALT), respiratory (BALT), and genitourinary tracts. This information is especially important in light of the current interest in the mechanisms, transmission, and prevention of infectious diseases such as AIDS, hepatitis, and tuberculosis.
Virtually all chapters have been authored by the original investigators responsible for key observations on which current concepts are based. This handbook will be an invaluable resource for a diverse group of both researchers and practicing clinicians.Molecular biologists, immunologists, veterinarians, public health workers, physicians in specialties from pediatrics to pulmonology, and graduate students of mucosal immunology will all find this handbook the most complete work on the subject.
"The quality of the volume is exactly as would be expected from the track records of the editorial team. It is superb. There are more than 100 contributors, from 17 countries, 4 continents; they form the right mix of acknowledgedexperts, who have breadth and depth of experience and knowledge, and clearly explain their work at the leading edges of the field."
"A readable book that is not just a mine of information, but offers workers in each subset of our complex discipline the opportunity to gain insight into and understanding of the issues being addressed by other groups. Such cross-fertilization will surely be an invaluable stimulus to new lines of interdisciplinary research."