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Equine Medicine, Surgery and Reproduction - E-Book

Equine Medicine, Surgery and Reproduction - E-Book

Tim Mair | Sandy Love | James Schumacher | Roger K. W. Smith | Grant Frazer

(2013)

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Book Details

Abstract

The new edition of this introductory-level textbook continues to offer a concise and approachable bridge between student lecture notes and more detailed clinical reference works. All aspects of equine medicine, surgery and reproduction are covered in a single, convenient volume. The second edition has been subject to an extensive revision, with each chapter updated and new chapters added to cover wound management, critical care, anaesthesia and sedation, and diagnostic imaging. While offering key information in an easily and quickly digested format for clinical veterinary students and practising veterinary surgeons, this second edition of Equine Medicine, Surgery and Reproduction will also be relevant to students undertaking equine science degrees, and to professional horse owners and trainers.

The wide range of international contributors, highly experienced and all experts in their fields, ensures that the new edition of this popular all-in-one resource remains as indispensable as ever.

  • Comprehensive coverage of all areas of equine medicine, surgery and reproduction
  • Easy-to-use format
  • Completely revised since the first edition with new chapters added
  • Now with over 100 new illustrations including colour photographs
  • Includes diagnostic and therapeutic information as well as descriptions of commonly employed clinical techniques
  • Includes lists of important differential diagnoses for common clinical signs

Table of Contents

Section Title Page Action Price
Front cover cover
Equine Medicine, Surgery and Reproduction i
Copyright page iv
Table of Contents v
Contributors vii
Preface ix
1 Upper alimentary system 1
Contents 1
1.1 Normal upper alimentary tract function: deglutition 2
Oral, pharyngeal and oesophageal phases of deglutition 2
Prehension 2
Mastication 2
Lingual function 2
Elevation of palate 2
Pharyngeal constriction 2
Laryngeal protection 2
Crico-pharyngeal relaxation 2
Primary and secondary oesophageal peristalsis 2
1.2 Diagnostic approach to cases of dysphagia 2
History – signs of dysphagia 2
Physical examination, external and oral inspection 3
Endoscopy per nasum 3
Radiography and fluoroscopy 4
Other imaging techniques 4
Oral examination under general anaesthesia 4
1.3 Aetiology of dysphagia: oral phase abnormalities 4
Facial palsy and lip lesions 4
Temporo-mandibular joint and hyoid disorders 4
Lingual abnormalities 5
Dental disorders 5
Congenital and acquired palatal defects 5
Other oral conditions: foreign bodies, neoplasia 5
1.4 Aetiology of dysphagia: pharyngeal phase abnormalities 5
Pharyngeal paralysis 5
Pharyngeal compression: strangles abscessation 5
Pharyngeal cysts, palatal cysts 5
Epiglottal lesions, including sub-epiglottic cysts 5
Laryngeal abnormalities 6
Fourth branchial arch defects (4-BAD) 6
1.5 Aetiology of dysphagia: oesophageal phase abnormalities 6
Megaoesophagus 6
Oesophageal obstruction (‘choke’) 6
Oesophageal strictures/stenosis 6
Intra-mural oesophageal cysts 6
Oesophageal rupture 6
Neoplasia 6
‘Wind-sucking’ 6
Grass sickness (See Chapter 3) 7
1.6 Oral trauma, mandibular fractures etc. 7
Pathogenesis 7
2 Gastroenterology 1. Colic 21
Contents 21
2.1 Introduction 21
False colics 22
Alimentary (true) colic 22
Classfication of colic 22
2.2 Pathophysiology of intestinal obstruction 22
Simple obstruction 22
Small intestine 22
Large intestine 23
Strangulating obstruction 24
Small intestine 24
Large intestine 25
2.3 Pharmacological management of colic 25
Aims of therapy 25
Relief of pain 25
Types of drug 25
Non-steroidal anti-inflammatory drugs (NSAIDs) 25
Dipyrone 25
Phenylbutazone 25
Meloxicam 25
Firocoxib 25
Flunixin meglumine 25
Sedatives 26
Xylazine 26
Detomidine 26
Romifidine 26
Acepromazine 26
Narcotic analgesics 26
Morphine 26
Pethidine 26
Butorphanol 26
Pentazocine 26
Spasmolytics 26
Atropine 26
Hyoscine 26
Laxatives 26
Mineral oil 26
Psyllium hydrophilic mucilloid 26
Osmotic laxatives 26
Dioctyl sodium succinate (DSS) 27
Intravenous and enteral fluids 27
Drugs that alter intestinal motility 27
Neostigmine methyl sulphate 27
Metoclopramide 27
Domperidone 27
Cisapride 27
Erythromicin 27
Lidocaine 27
Fluids 27
2.4 Common types of colic 27
Spasmodic colic 27
Aetiology and pathogenesis 27
Clinical signs 27
Treatment 27
Differential diagnosis 28
Impaction colics 28
Prevention 28
Clinical signs 28
Diagnosis 28
Treatment 29
Flatulent / tympanitic colic 29
Aetiology and pathogenesis 29
Clinical signs 30
Therapy 30
Prognosis 30
2.5 Grass sickness 30
2.6 Anterior enteritis (proximal enteritis, gastroduodenal jejunitis) 30
Clinical signs and diagnosis 30
Laboratory data 31
Gross intestinal lesions 31
Histopathology 31
Aetiology 31
Treatment 31
2.7 Approach to diagnosis in colic cases 32
Signalment 32
History 32
Clinical examination 33
Observation 33
Examination of the cardiovascular system 33
Heart rate and pulse character 33
Mucous membranes 34
Capillary refill time 34
Examination of the abdomen 34
Abdominal distension 34
Auscultation and palpation 34
Rectal examination 34
Abdominal paracentesis (abdominocentesis) 34
Nasogastric intubation 35
State of peripheral perfusion and hydration 35
Packed cell volume (PCV) and total protein 35
Imaging techniques 35
Classification into categories 35
2.8 The decision for surgery 35
2.9 Preparation of the horse prior to transport to a surgical centre 37
2.10 The surgical management of the equine colic case – general points 37
Premedication and anaesthesia 37
Induction and maintenance 37
Recovery from anaesthesia 38
Celiototomy (laparotomy) techniques 38
Examination of the small intestine 38
Examination of the large colon 38
Evaluation of gut viability 39
Resection of small intestine 40
Resection and anastomosis 40
Closure of the mesentery 40
Anastomosis of intestinal segments of different diameters 40
Resection of the ileum 40
Automated mechanical stapling techniques 41
Resection of large intestine 42
Caecum 42
Large colon 42
Small colon 42
Closure of the midline incision (Figure 2.4) 43
2.11 Postoperative management of the colic case 44
Monitoring protocol 44
Food and water 44
Fluid therapy 44
Catheter care 44
Analgesia and anti-inflammatory therapy 44
Antibiotics 45
2.12 Postoperative complications 45
Complications during recovery from anaesthetic 45
Myopathy 45
Long-bone fractures 45
Complications during the hospitalization period 45
Shock 45
Endotoxamis and SIRS 45
Postoperative ileus (POI) 45
POI falls into one of two categories: 46
Colic 46
Wound complications 46
Thrombophlebitis 46
Laminitis 46
Adhesions 47
Postoperative diarrhoea 47
Septic Peritonitis 47
Further reading 47
3 Gastroenterology 2. Hepatic and intestinal disorders 49
Contents 49
Liver disease 49
3.1 Diagnostic approach to liver disease 50
History 50
Physical examination 51
Laboratory investigation of liver disease 51
Liver biopsy 51
Diagnostic ultrasound in liver disease 51
3.2 Pyrrolizidine toxicity 51
3.3 Theiler’s disease (acute hepatic necrosis, serum hepatitis, serum sickness) 52
3.4 Cirrhosis 52
3.5 Liver fluke 52
3.6 Cholangiohepatitis and choledocholithiasis (biliary calculi) 52
3.7 Chronic active hepatitis 53
3.8 Iron overload (haemochromatosis) 53
3.9 Hydatid cysts 54
3.10 Other hepatic diseases 54
3.11 Treatment for liver failure 54
Pancreatic diseases 54
3.12 Pancreatic diseases 54
Equine grass sickness 54
3.13 Equine grass sickness (equine dysautonomia) 54
Epidemiology 55
Pathogenesis 55
Clinical signs 55
Acute form 55
Sub-acute form 55
4 Abdominal cavity 67
Contents 67
4.1 Hernias 67
Definitions 67
Types of hernia 67
Umbilical hernias 67
Examination of the hernia 68
Closed reduction 68
Open reduction 68
Ventral hernias 69
Diagnosis 69
Treatment 69
Incisional hernias 69
Prepubic tendon rupture 70
Epiploic foramen incarceration 70
5 Disorders of the ear, nose and throat 77
Contents 77
5.1 Diseases of the external ear 78
Anatomical considerations 78
Clinical signs of otitis externa 78
Investigation of ear disorders 78
Temporal teratoma 78
Parasitic otitis 79
Chronic keratinization plaques 79
Foreign bodies 79
Neoplasia: sarcoids 79
Neoplasia: other ear tumours 79
5.2 Diseases of the middle ear 79
Anatomy and function of the middle ear 79
Otitis media 79
Temporohyoid osteoarthropathy (THO) 79
Otitis interna/peripheral vestibular disease 79
5.3 Diseases of the auditory tube diverticulum (ATD) (guttural pouches) 80
Anatomy and function of ATDs 80
Signs of ATD diseases 80
Physical examination of ATDs 80
Endoscopy of ATDs 80
Radiographic examination of ATDs 80
Topical treatment of ATDs 80
Surgical approaches to ATD 80
5.4 Guttural pouch tympany 81
Aetiology 81
Clinical signs and diagnosis 81
Treatment 81
Prognosis 81
5.5 Diverticulitis of the guttural pouch 81
Aetiopathogenesis 81
‘Strangles’ 81
Chronic ATD empyema and chondroids 81
Chronic ATD diverticulitis 81
5.6 Guttural pouch mycosis 82
Aetiopathogenesis 82
Clinical signs 82
Diagnosis 82
Treatment 82
Prognosis 82
5.7 Other ATD disorders 83
6 Lower respiratory tract 111
Contents 111
6.1 Diagnostic approach to lower respiratory tract diseases 111
History 111
Physical examination 111
Respiratory rate, pattern and character 112
Nasal discharge 112
Cough 112
Palpation 112
Auscultation 112
Percussion 113
Endoscopy 113
Tracheal aspiration 114
Bronchoalveolar lavage (BAL) 115
Endoscopic BAL technique 115
Blind BAL technique 115
Thoracic radiography 116
Diagnostic ultrasound 116
Thoracocentesis 117
Pleuroscopy (thoracoscopy) 117
Haematology 117
Other diagnostic tests 117
6.2 Diagnostic features of the common lower respiratory tract diseases of the adult horse 117
6.3 Recurrent airway obstruction (RAO) 117
Aetiology 117
Pathogenesis 118
Epidemiology 119
Clinical signs 119
Subclinical disease 119
Mild clinical disease 119
Severe clinical disease 119
Diagnosis 119
Differential diagnosis 120
Treatment 120
To relieve clinical signs 120
Systemic and oral corticosteroid therapy 120
Inhaled corticosteroids 120
To prevent recurrence of disease 121
Prognosis 121
Prevention 121
6.4 Acute obstructive pulmonary disease 121
Clinical signs 121
7 Cardiovascular system 133
Contents 133
7.1 Overview of heart disease in the horse 133
7.2 Evaluation of cardiovascular function 133
Signalment 133
Medical history 133
Physical examination 134
Inspection and palpation 134
Auscultation 134
Ancillary diagnostics 138
Electrocardiography 138
Echocardiography 140
Exercise testing 140
Clinical laboratory tests 141
Arterial blood pressure 142
Radiography 142
Cardiac catheterization 142
7.3 Structural heart disease 142
Congenital malformations 142
Ventricular septal defect (VSD) 142
Acquired valvular heart disease 143
Mitral regurgitation (MR) 144
Aortic insufficiency (AI) 144
Tricuspid regurgitation (TR) 145
Pulmonic insufficiency (PI) 146
Endocarditis 146
Pericardial disease 147
Myocardial disease 147
7.4 Heart failure 148
7.5 Cardiac rhythm disturbances 149
Physiological arrhythmias 150
First and second degree atrioventricular (AV) block 150
Sinus bradycardia, sinus arrhythmia, sinus tachycardia 150
Sinoatrial (SA) block, sinus arrest 150
Pathological arrhythmias 151
Atrial premature complexes and atrial tachycardia 151
Atrial fibrillation 151
Junctional and ventricular arrhythmias 153
Conduction disturbances 155
7.6 Vascular disease 156
Jugular thrombophlebitis 156
Aorto-iliac thrombosis 157
Vascular ruptures 158
Further reading 158
8 Diseases of the equine urinary tract 159
Contents 159
8.1 Evaluation of the urinary system 159
Renal function and water balance in the normal horse 159
Physical examination 160
Ultrasonographic examination 160
Endoscopic examination 160
Percutaneous renal biopsy 160
Laboratory assessment of urinary tract disease 160
Renal disease vs. renal failure 161
8.2 Prerenal azotaemia 161
Aetiology 161
Pathogenesis 161
Clinical signs 161
Clinicopathological signs 161
Diagnosis 161
Treatment 161
8.3 Acute renal failure due to renal disease 162
Aetiology 162
Pathogenesis 162
Clinical signs of renal tubular necrosis 162
Diagnosis 162
Treatment 162
Prognosis 162
8.4 Chronic renal failure (CRF) 162
Aetiology and pathogenesis 162
9 Endocrinology 181
Contents 181
9.1 Anhidrosis (dry coat syndrome) 181
Aetiology 181
Pathogenesis 181
Clinical signs 181
Diagnosis 182
Treatment and prevention 182
9.2 Pituitary pars intermedia dysfunction (PPID) or equine Cushing’s disease (ECD) 182
Aetiology 182
Clinical signs and proposed pathogenesis 183
Diagnosis 184
Treatment 184
9.3 Hypoadrenocorticism (adrenal insufficiency, turn-out syndrome, steroid let down syndrome) 185
Aetiology and pathogenesis 185
Clinical signs 185
Diagnosis 185
Treatment 185
9.4 Phaeochromocytoma 185
Clinical and clinicopathological signs 185
10 Haematopoietic and immune systems 195
Contents 195
10.1 Diagnostic approach to haematopoietic and immune system diseases 195
History 195
Physical examination 196
Non-specific systemic signs 196
Mucous membranes 196
Haemorrhage 196
Palpation 196
Peripheral blood evaluation 196
Erythrocytes 196
Leukocytes 197
Platelets 197
Miscellaneous tests 198
Bone marrow evaluation 198
Evaluation of haemostatic function 198
Ancillary diagnostic tests 198
Immune function evaluation 199
Immunoglobulin assays. 199
Lymphocyte typing. 199
Blood typing. 199
Cellular immune function. 199
10.2 Diagnostic features of common haematopoietic and immune disorders of horses 199
10.3 Anaemia secondary to haemorrhage 200
Haemorrhage: aetiology and pathogenesis 200
Clinical signs 201
Diagnosis 201
Treatment 201
10.4 Immune-mediated haemolytic anaemia 201
Pathogenesis 201
11 Neurology 211
Contents 211
11.1 Diagnostic approach to neurological diseases 212
History 212
Physical examination 212
Examination of the head 212
Examination of gait and posture 213
Examination of the neck and forelimbs 214
Examination of the trunk and hind limbs 214
Examination of the tail and anus 214
Neurological examination of foals 215
Ancillary diagnostic tests 215
Cerebrospinal fluid (CSF) collection 215
Atlanta-occipital (AO) space. 215
Lumbosacral (LS) space. 215
CSF analysis 215
Radiology 215
Electrodiagnostics 215
Necropsy 215
The brain 216
11.2 Foals 216
Anencephaly 216
Hydrocephalus 216
Perinatal asphyxia syndrome/hypoxic ischaemic encephalopathy/neonatal encephalopathy/neonatal maladjustment syndrome (dummies, barkers, wanderers) 216
Congenital cerebellar disease 216
Cerebellar abiotrophy of Arabs 216
Clinical signs 216
Other cerebellar conditions 216
Idiopathic seizures 216
11.3 Trauma 217
Forebrain syndrome 217
12 Ophthalmology 235
Contents 235
12.1 Examination of the eye and adnexa 235
History 236
Ophthalmic equipment and examination techniques 236
Focal light source 236
Magnification 236
Restraint 236
Protocol for ophthalmic examination 236
Examination in daylight 236
Examination in a darkened area 237
Ancillary diagnostic techniques 238
12.2 Techniques in ocular therapeutics 239
Local therapy 239
Topical medication 239
Subconjunctival injection 242
Subconjunctival micro-osmotic pumps 242
Intracameral injection 242
Intralesional medication 242
Intravitreal cyclosporine A implant 242
Systemic medication 242
Surgery 242
12.3 Globe and orbit 243
Congenital abnormalities 243
Acquired abnormalities 243
Phthisis bulbi 243
Exophthalmos 243
Endophthalmos 244
Prolapse of orbital fat 244
Glaucoma 244
Endophthalmitis and panophthalmitis 244
Clinical signs 244
13 Dermatology 261
Contents 261
13.1 Diagnostic approach to skin diseases 261
History 261
Physical examination 262
Differential diagnosis list 262
Diagnostic tests 262
Skin scrapings 262
Skin cytology 262
Trichogram 263
Microbial culture 263
Skin biopsies 263
Specialized tests 263
Skin diseases in the horse 263
13.2 Skin diseases characterized by pruritus (itch) 263
Ectoparasitic skin diseases characterized by pruritus 264
Pediculosis (lice) 264
14 Reproduction 283
Contents 283
14.1 The non-pregnant mare 283
Stages of the oestrous cycle 283
Oestrus 283
Dioestrus 284
Vernal and autumn transition stages 285
Seasonal anoestrus 285
Examination of the mare for breeding soundness 285
History 285
General physical 285
Examination of external genitalia 285
Examination of internal genital tract 285
Endometrial swabbings for microbiological culture 286
Endometrial cytology 286
Vaginal examination 286
Endometrial biopsy 287
Endoscopy 287
Hormone analysis 287
Diseases of the mare’s reproductive tract 287
A. Enlarged ovaries 287
Ovarian neoplasm 287
Clinical signs 287
15 Orthopaedics 1. Diagnosis of lameness/diseases of joints and bones 309
Contents 309
15.1 Diagnostic approach to lameness 309
History 309
Physical examination 310
Gait evaluation 310
Provocative tests 311
Regional analgesic techniques 311
Peripheral nerve blocks of the lower limb 312
Anatomy 312
Perineural analgesia of the distal limb 313
Palmar/plantar digital nerve block (PDNB) (Figure 15.1) 313
Abaxial sesamoid nerve block (ASNB) (Figure 15.1) 313
Low 4-point nerve block (low palmar and palmar metacarpal nerve block) (L4-PNB) (Figure 15.1) 313
High 4-point nerve block (high palmar and palmar metacarpal nerve block) (H4-PNB) (Figure 15.1) 313
Desensitization of the origin of the suspensory ligament (SL) 313
Peripheral nerve blocks of the upper limb 314
Median and ulnar nerve blocks 314
Median nerve block 314
Ulnar nerve block 314
Tibial and peroneal nerve blocks 314
Tibial nerve block 314
Peroneal nerve block 314
Intrasynovial analgesia 314
Analgesia of the navicular bursa 314
Analgesia of the distal interphalangeal joint 314
Analgesia of the proximal interphalangeal joint (PIP) 314
Anaesthesia of the metacarpo/metatarsophalangeal (fetlock) joint 314
Analgesia of the digital synovial sheath 315
Analgesia of the middle carpal joint 315
Analgesia of the antebrachiocarpal joint 315
Analgesia of the elbow joint 315
Analgesia of the shoulder joint 315
Analgesia of the tarsometatarsal joint 315
Analgesia of the distal intertarsal joint 315
Analgesia of the tarsocrural joint 315
Analgesia of the femoropatellar joint 315
Analgesia of the medial compartment of the femorotibial joint 315
Analgesia of the lateral compartment of the femorotibial joint 315
Arthrocentesis and analysis of synovial fluid 315
Radiography (see Chapter 25) 316
Foot 316
Pastern 316
Fetlock 316
Carpus 316
Elbow 316
Shoulder 316
Hock 316
Stifle 316
Hip 316
Ultrasonography (see Chapter 25) 316
Technique 316
Metacarpal region (Figure 15.2) 317
Pastern region (Figure 15.3) 317
Interpretation 317
Indications for the use of ultrasonography 318
Nuclear scintigraphy (see Chapter 25) 318
Thermography 318
Computed tomography (CT) (see Chapter 25) 318
Magnetic resonance imaging (MRI) (see Chapter 25) 318
Diagnostic arthroscopy 318
15.2 Joint diseases 319
Idiopathic synovitis 319
Definition 319
Aetiopathogenesis 319
Treatment 319
Traumatic arthritis/synovitis 319
Aetiology 319
Pathogenesis 319
Pathology 319
Clinical signs 319
Further tests 320
Treatment 320
Osteoarthritis (degenerative joint disease) 320
Definition 320
Classification 320
Pathogenesis 320
Pathology 320
Clinical signs 321
Diagnosis 321
Imaging techniques. 321
Radiology (see Chapter 25) 321
Scintigraphy 321
MRI 321
Arthroscopy (Figure 15.5) 321
Treatment 321
Osteochondritis dissecans (OCD) 321
Epidemiology 322
16 Orthopaedics 2. Diseases of the foot and distal limbs 329
Contents 329
16.1 Diseases of the foot 330
Cracks of the hoofwall 330
Classification 330
17 Orthopaedics 3. The proximal limbs 369
Contents 369
17.1 Carpus 370
Anatomy 370
Bones 370
Joints 370
Traumatic arthritis, osteoarthritis (degenerative joint disease) 370
Aetiology and pathogenesis 370
Carpal fractures 370
Clinical signs 371
Radiology 371
Soft-tissue swelling 371
Entheseophytes 371
Osteophytes 371
Paramarginal subchondral bone lysis 372
Subchondral bone densification 372
OA of the carpometacarpal joint 372
Treatment 372
Osteochondritis dissecans (OCD) (see Chapter 15) 372
Subchondral cystic lesions (SCLs) (see Chapter 15) 372
Septic arthritis 372
Angular limb deformities 372
Aetiology 372
Pathogenesis 372
History 373
Physical examination 373
Radiography 373
Radiology 373
Treatment 373
Carpal canal syndrome 374
18 Orthopaedics 4. The back and pelvis 389
Contents 389
18.1 Anatomy of the horse’s back 389
18.2 Diagnostic approach to diseases of the horse’s back 389
History 389
Examination at rest 390
Conformation 390
Muscle wastage 390
Swellings and marks 391
Palpation/manipulation 391
Examination at exercise 391
In hand 391
Lunging 391
Riding 391
Aids to diagnosis 391
Clinical biochemistry 391
Radiography (see Chapter 25) 391
Scintigraphy (see Chapter 25) 391
Ultrasonography (see Chapter 25) 391
Local analgesia 392
Systemic analgesia 392
Other diagnostic tests 392
18.3 Disorders of the horse’s back – conditions that may present as a back problem 392
Hind limb lameness 392
Temperamental or managerial difficulties 392
Hind limb incoordination – neurological disease 392
18.4 Vertebral column deformities 392
19 Infectious diseases and parasitology 399
Contents 399
19.1 Investigation of infectious disease 400
19.2 Diagnosis of viral and bacterial infections 400
Diagnosis of viral infections 400
Diagnosis of bacterial infections 401
19.3 Equine influenza 401
The virus 401
Epidemiology 401
Pathogenesis 401
Clinical signs 401
Diagnosis 401
Treatment 401
Control of outbreak 401
Prevention 402
19.4 The equine herpesviruses 402
The viruses 402
Equine herpesvirus 1 (rhinopneumonitis) 402
Pathogenesis and epidemiology 402
Clinical signs 402
Respiratory disease 402
Abortion (see Chapter 14). 402
Neonatal disease (see Chapter 20). 402
Neurological disease (see Chapter 11). 402
Diagnosis 403
20 Diseases of the foal 423
Contents 423
20.1 Prematurity/dysmaturity 424
Gestational length 424
Definitions 424
Risk factors 424
Clinical characteristics of prematurity 424
Clinical characteristics of postmaturity 424
Pathophysiology and diagnostic findings 424
Treatment (see Chapter 26) 424
Prognosis 425
Prevention 425
20.2 Systemic diseases involving multiple body systems 425
Sepsis 425
Definitions 425
Aetiology 426
Clinical signs 426
Diagnosis 426
Treatment 426
Prognosis 426
Prevention 426
Shock (see Chapter 26) 426
Classifications 426
21 Muscle disorders and performance problems 451
Contents 451
21.1 Examination of the muscular system 451
Physical examination 451
Clinical pathology 451
Creatinine phosphokinase 451
Lactate dehydrogenase 452
Aspartate aminotransferase 452
Interpretation of enzyme levels 452
Muscle biopsy 452
Electromyography 452
21.2 Congenital/familial disease 452
Myotonia 452
Aetiology/pathogenesis 452
22 Metabolic diseases and toxicology 461
Contents 461
22.1 Calcium metabolism 462
Complexed calcium 462
Protein-bound calcium 462
Ionized calcium 462
22.2 Calcium homeostasis 462
Parathyroid hormone (PTH) 462
Calcitonin 462
1,25-Dihydroxycholecalciferol 462
22.3 Hypercalcaemia 462
Renal failure 462
Plant toxicity 462
Other causes of hypercalcaemia 462
22.4 Hypocalcaemia 462
Lactation tetany/transport tetany/idiopathic hypocalcaemia 462
Synchronous diaphragmatic flutter 463
Blister beetle (cantharidin) toxicosis 463
Other causes of hypocalcaemia 463
22.5 Phosphorus metabolism 463
22.6 Hyperphosphataemia 463
Secondary nutritional hyperparathyroidism 463
22.7 Hypophosphataemia 463
22.8 Sodium metabolism 463
22.9 Hypernatraemia 463
23 Principles of wound management 469
Contents 469
23.1 Definition of a wound 469
23.2 Classification of wounds 469
Open wounds 469
Closed wounds 470
23.3. Assessment of the wounded horse 470
General assessment 470
Penetrating wounds over the abdomen or thorax 470
23.4 Detailed assessment of the wound 470
Initial assessment 470
Suspected synovial involvement 470
Blood supply 470
Factors that impair healing 470
23.5 Stages of wound healing 473
Inflammatory phase 473
Debridement phase 474
Repair phase (sometimes called the fibroblastic or proliferative phase) 474
Maturation phase (sometimes called the remodeling phase) 474
23.6 Methods of wound management 474
23.7 Primary (first intention) healing 474
Definition 474
Criteria for primary closure 474
Preparation of a wound for primary closure 475
Surgical debridement 475
Debridement by lavage 475
Solutions for lavage 476
Antiseptics added to lavage solutions 476
Povidone iodine (PI) 476
Chlorhexidine 476
Local anaesthesia 476
Options for wound closure 476
Drains 476
Disadvantages of drains 478
Skin tension 478
23.8 Delayed primary closure (third intention healing) 478
23.9 Delayed secondary closure 479
23.10 Second intention healing 479
Wound expansion 479
Contraction 479
Epithelialization 480
Granulation tissue 480
23.11 Skin grafting 481
Indications for grafting 481
Graft classification 481
Physiology of graft acceptance 482
Causes of graft failure 482
Fluid accumulation 482
Infection 482
Motion 482
Preparing the wound for grafting 482
Preparing the donor site 482
Sheet grafts 482
Full-thickness sheet grafts 482
Split-thickness sheet grafts 483
Meshing sheet grafts (Figure 23.12) 484
Techniques of applying sheet grafts 484
Acceptance and cosmesis 485
Island grafting 485
1. Punch grafting 485
2. Pinch grafts 486
3. Tunnel grafting 486
4. Aftercare of the donor site 487
5. Aftercare of the recipient site 487
Allografts and xenografts 487
Storage of grafts 487
Further reading 487
24 Sedation and anaesthesia 489
Contents 489
24.1 Risks associated with equine anaesthesia 489
24.2 Patient preparation 489
24.3 Drugs used for sedation 490
Phenothiazines 490
Clinical use of acepromazine 490
Alpha2 adrenergic agonists 490
Clinical use of alpha2 agonists 490
Opioids 490
Benzodiazepines 490
24.4 Sedation of adult horses 490
Sedation using constant rate infusions (CRI) 491
24.5 Sedation of foals 491
Benzodiazepines (e.g. diazepam or midazolam [0.05–0.1 mg/kg i.v.]) 491
Benzodiazepine and ketamine 491
24.6 Induction of general anaesthesia in adults 491
Induction regimens 491
Ketamine and an alpha2 agonist 491
Ketamine/benzodiazepine and an alpha2 agonist 492
Thiopental and an alpha2 agonist 492
Tiletamine-zolazepam (TZ) and an alpha2 agonist 492
Guaiphenesin with thiopental or ketamine 492
Immobilon 492
24.7 Prolonging anaesthesia with injectable drugs 492
24.8 Total intravenous anaesthesia 492
24.9 Inhalational anaesthesia 493
Advantages of inhalational anaesthetics 493
Disadvantages of inhalational anaesthetics 493
Recovery from inhalational anaesthesia 493
24.10 Anaesthesia of foals 493
Induction with an inhalational anaesthetic 493
Induction with injectable anaesthetics 493
Maintenance of anaesthesia 493
24.11 Analgesia 494
Non-steroidal anti-inflammatory drugs (NSAIDs) 494
Flunixin meglumine (0.25–1.1 mg/kg, i.v., q8–12 h) 494
Phenylbutazone (2.2–4.4 mg/kg, i.v., or per os, q12–24 h) 494
Ketoprofen (1–2 mg/kg, i.v.; q24 h) 494
Opioids 494
Morphine (0.1–0.3 mg/kg, i.m.; q4–6 h) 494
Butorphanol (0.02–0.04 mg/kg, i.v., i.m.; q2–4 h) 494
Meperidine (1–2 mg/kg, i.m.; q2–4 h) 494
Alpha2 agonists 494
Tramadol 494
Lidocaine infusions 494
Ketamine infusions 494
24.12 Epidural anaesthesia and analgesia 494
Indications for epidural injections 495
Caudal epidural technique (See Figure 24.1) 495
Anterior (cranial) epidural technique 496
Drugs administered by the caudal epidural route 496
Local anaesthetics (e.g. lidocaine, mepivacaine, ropivacaine) 496
Alpha2 agonists (e.g. xylazine, detomidine) 496
Opioids (e.g. morphine, methadone, hydromorphone) 496
Tramadol 496
Ketamine 496
Doses and recommendations (see Table 24.1) 496
24.13 Complications of general anaesthesia 496
Complications at induction 496
Intracarotid injection 496
Administration of the incorrect drug 496
Haematoma formation 496
Perivascular injections 496
Injury resulting from poor inductions 497
Intraoperative complications 497
Hypoxaemia 497
Hypotension 497
Hypercapnia 497
Postoperative complications 497
Myopathy (see Chapter 21) 497
Neuropathy 497
Further reading 497
25 Equine diagnostic imaging 499
Contents 499
25.1 Radiography 499
Introduction 499
Underlying physics 499
How are X-rays produced? 499
How do X-rays interact with matter? 500
How are X-rays registered and how is that transformed into an image? 500
What image parameters characterize a radiograph? 500
What can radiographs show? 501
When do we see changes in bone on radiographs? 501
How does an increase in bone production appear on radiographs? 501
How does a decrease in bone production appear on radiographs? 501
What can radiographs tell us about soft tissues? 501
Indications for radiography in the horse 502
Interpretation of radiographs 502
Pitfalls in radiographic interpretation 502
How to view radiographs? 504
How to assess radiographs? 504
Radiographic changes associated with musculoskeletal problems 509
Osteoarthritis (Figures 25.4, 25.6, 25.7) 509
Osteochondrosis (Figures 25.10, 25.11) 510
Infectious osteitis and osteoarthritis (Figure 25.1) 510
Enthesiopathies (Figures 25.5, 25.6) 510
(Sub)luxations (Figure 25.13) 510
Fractures 510
Advantages/disadvantages of radiography 516
Advantages 516
Disadvantages 516
Radiography and radiographic anatomy 516
Patient preparation 516
Radiographic projections 516
Exposure settings 518
Exposure adjustment 518
Focus–film distance 519
Labelling of cassettes 519
Scatter reduction 519
Radiography of the different anatomical regions 519
The foot 519
Indication 519
Equipment 519
Preparation 519
Radiographic projections 519
Radiographic technique 519
Radiographic anatomy 522
Radiopathology 524
The fetlock 527
Indication 527
Equipment 527
Preparation 527
Radiographic projections 527
Technique 528
Radiographic anatomy 529
Radiopathology 531
Carpus 533
Indications 533
Equipment 533
Preparation 534
Radiographic projections 534
Technique 534
Radiographic anatomy (Figures 25.51 to 25.54) 534
Radiopathology 535
The elbow 537
Indication 537
Equipment 538
Projections (mediolateral and cranio-caudal) – technique 538
Radiographic anatomy 538
Radiopathology 538
The shoulder 539
Indication 539
Equipment 539
Projections 539
Technique 539
Radiographic anatomy 539
Radiopathology 539
The tarsus 540
Indications 540
Equipment 540
Preparation 540
Radiographic projections (Figures 25.59 to 25.62) 540
Technique 541
Radiographic anatomy (Figures 25.59 to 25.62) 542
Radiopathology 543
The stifle 543
Indications 543
Equipment 543
Preparation 544
Radiographic projections 544
Technique 544
Radiographic anatomy 544
Radiopathology 544
The pelvis 545
Indications 545
Equipment 545
Projections 545
Technique 546
Radiographic anatomy 546
Radiopathology 546
The head 547
Indications 547
Equipment 547
Projections 547
Technique 547
Radiographic anatomy 548
Radiopathology 548
The thorax 549
Indications 549
Equipment 549
Projections 549
Technique 549
Evaluating the quality of the radiograph 549
Radiopathology 549
The neck 550
Indication 550
Equipment 550
Projections 550
Technique 550
Radiographic anatomy 550
Radiopathology 550
Myelography 551
The back 551
Indication 551
Equipment 551
Projections 551
Technique 551
Radiographic anatomy 551
Radiopathology 551
25.2 Ultrasonography 552
Introduction 552
Ultrasound physics 552
Indications in the horse 552
Orthopaedic applications (see Chapter 15) 552
Non-orthopaedic applications (see Chapters 2, 3, 4, 6, 7, 8 and 14) 552
Procedure 553
Interpretation 553
Ultrasonographic parameters. 553
Terminology 553
Tissue characteristics 553
Common artefacts 553
Advantages/disadvantages of ultrasonography 554
Advantages 554
Disadvantages 554
25.3 Scintigraphy 554
Introduction 554
Underlying principle 554
Choice of radiopharmaceutical and dose 554
Detection of radiation and image formation 554
Indications in the horse 554
Procedure 555
Interpretation 555
Advantages/disadvantages of scintigraphy 556
Advantages 556
Disadvantages 556
25.4 Computed tomography (CT) and magnetic resonance imaging (MRI) 556
Computed tomography (CT) 556
Underlying principle 556
Interpretation 556
Indications in the horse 556
Magnetic resonance imaging (MRI) 558
History 558
Underlying principle 558
Advantages/disadvantages of MRI 558
Indications in the horse 558
Further reading 559
Radiography and radiology 559
Ultrasonography 559
Scintigraphy 559
CT and MRI 559
Radiation safety 559
26 Common problems and techniques in equine critical care 561
Contents 561
26.1 Principles of fluid therapy 561
Reasons to administer fluids 561
Components of a fluid plan 562
Fluid volume 562
Type of fluid 562
Route of fluid administration 563
Rate of fluid administration 563
Management of common electrolyte and acid–base disturbances 564
Sodium derangements 564
Hyponatraemia 564
Hypernatraemia 564
Potassium derangements 565
Hypokalaemia 565
Hyperkalaemia 565
Other electrolyte derangements 565
Hypocalcaemia 565
Hypomagnesaemia 565
Metabolic acidosis 565
Metabolic alkalosis 565
Fluid therapy in neonatal foals: special considerations 565
26.2 Pathophysiology and management of shock 565
Definition of shock 565
Pathophysiology of shock 566
Classifications and types of shock 566
Hypovolaemic shock 566
Cardiogenic shock 566
Distributive shock 566
Sepsis 566
Anaphylaxis 566
Obstructive shock 566
Metabolic shock 567
Stages of shock 567
Stage I: Compensated (also known as hyperdynamic) shock 567
Stage II: Early decompensated shock 567
Stage III: Late decompensated (also known as irreversible) shock 567
Management of shock 567
Therapies directed at restoring cardiac output 567
Therapies directed at maximizing the oxygen content in the blood 568
Therapies directed at correcting the underlying disease 568
Monitoring 568
26.3 Administration of blood products in equine critical care 568
Commonly used blood products 568
Plasma 568
Whole blood 568
Products used in specific circumstances 569
Blood transfusions 569
Indications for blood transfusion 569
General considerations for whole blood transfusion 569
Whole blood collection and administration 569
Supportive care and other management considerations in the anaemic patient 571
Treatment of the underlying cause 571
Plasma transfusions 571
Indications for plasma transfusion 571
Plasma and serum products 571
Fresh-frozen plasma (FFP) 571
Fresh plasma (FP) 571
High-gammaglobulin plasma 572
Hyperimmune plasma and serum 572
Administration and monitoring 572
Alternatives to plasma – synthetic colloids 572
26.4 Nutritional support in the critically ill horse and foal 572
Introduction and key points 572
Nutritional requirements 572
Enteral nutrition 572
Parenteral nutrition 573
Circumstances necessitating parenteral nutrition 573
Types of parenteral nutrition 573
Intravenous fluids containing dextrose 573
Partial parenteral nutrition (PPN) 573
Total parenteral nutrition (TPN) 573
Important considerations in the administration of parenteral nutrition 573
Preparation and administration 573
Rate of administration 573
Monitoring and complications 574
Some other potential complications 574
Nutrition in the sick foal: special considerations 574
26.5 Evaluation and management of the sick neonatal foal 574
Introduction 574
Evaluation of the neonatal foal 574
History 574
Physical examination 574
Ancillary diagnostics 575
Stabilization and management of the sick neonatal foal 576
General supportive/nursing care 577
Gastric ulcer prophylaxis 577
Additional management 577
Colic 577
Respiratory disease 577
Neonatal isoerythrolysis (NI) 577
Neonatal encephalopathy 577
Septic arthritis/septic physitis 577
26.6 Management of acute respiratory distress (See also Chapters 5 and 6) 578
Causes of respiratory distress 578
Index 585
A 585
B 587
C 587
D 589
E 590
F 591
G 592
H 593
I 594
J 595
K 595
L 595
M 596
N 597
O 597
P 598
Q 600
R 600
S 601
T 603
U 604
V 605
W 605
X 606
Y 606
Z 606