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Dermatology

Dermatology

David Gawkrodger | Michael R Ardern-Jones

(2012)

Additional Information

Book Details

Abstract

This concise textbook of dermatology is aimed at medical students, those preparing for the MRCP and MRCGP examinations and specialist nurses. The information is presented in a highly accessible format, using double page spreads for each topic. Extensive use of colour for both clinical photographs and graphics makes for a superb appearance. For review for examination preparation key point boxes are provided. In this fourth edition extensive revision has been made to the contents to reflect changes in the understanding of dermatological conditions at a molecular level and the changes in clinical practice. In addition the use of the internet for dermatological information by both doctors and patients is reviewed.

  • Information presented in easy to access double-page spreads.
  • Highly illustrated with full colour photographs and graphics.
  • Summary boxes for examination preparation.
  • Covers the subject from basic molecular mechanisms through to the principles of medical and surgical treatment.
  • Gives references to internet URLs for further information.
  • Includes a glossary of dermatological terms.

Table of Contents

Section Title Page Action Price
Front cover cover
Dermatology i
Copyright page iv
Preface to the fifth edition v
Preface to the first edition v
Acknowledgements vi
Table of Contents vii
Basic principles 1
Microanatomy of the skin 2
Introduction 2
Epidermis 2
Basal cell layer (stratum basale) 2
Prickle cell layer (stratum spinosum) 2
Granular cell layer (stratum granulosum) 2
Horny layer (stratum corneum) 3
Dermis 3
Subcutaneous layer 3
Web resource 3
Derivatives of the skin 4
Hair 4
Diseases 27
Eruptions 28
Psoriasis - Epidemiology, pathophysiology and presentation 28
Definition 28
Epidemiology 28
Aetiopathogenesis 28
Genetics 28
Epidermal kinetics and metabolism 28
Precipitating factors 28
Pathology 28
Clinical presentation 28
Plaque 28
Guttate 29
Flexural 29
Localized forms 29
Generalized pustular 29
Nail involvement 29
Web resource 29
Psoriasis -Management and complications 30
Management 30
Topical therapy 30
Vitamin D analogues 30
Topical corticosteroids 30
Coal tar preparations 30
Dithranol (anthralin) 30
Retinoids 30
Keratolytics and scalp preparations 30
Systemic therapy 30
Methotrexate 31
Retinoids 31
Ciclosporin 31
Biologic agents and other systemic treatments 31
Complications 31
Psoriatic arthropathy 31
Erythrodermic psoriasis 31
Web resource 31
Psoriasis - Biologics 32
Scientific background 32
Effects of activated chronic inflammatory cytokines 32
Associated joint disease 32
Types of biologic available 32
Pretreatment screening 33
Effectiveness of biologics 33
Therapeutic algorithm 33
Side-effects of biologics 33
Use of biologic agents in other skin diseases 33
Web resources 33
Eczema -Basic principles/contact dermatitis 34
Allergy and autoimmunity 76
Urticaria and angioedema 76
Aetiopathogenesis 76
Pathology 76
Clinical presentation 76
Chronic idiopathic urticaria 76
Acute urticaria 76
Physical urticarias 76
C1 esterase inhibitor deficiency 77
Urticarial vasculitis 77
Differential diagnosis 77
Investigation 77
Management 77
Antihistamines 77
Corticosteroids 77
Adrenaline (epinephrine) 77
Diet 77
Web resource 77
Blistering disorders 78
Pemphigus 78
Internal medicine 84
Skin changes in internal conditions 84
Skin signs of endocrine and metabolic disease 84
Diabetes mellitus 84
Thyroid disease 84
Flushing 84
Hyperlipidaemia 84
Skin signs of nutritional and other internal disorders 85
Nutritional deficiency 85
Gastrointestinal disease 85
Other internal disorders 85
Skin changes in pregnancy 85
Web resource 85
Drug eruptions 86
Aetiopathogenesis 86
Clinical presentation 86
Drug-induced exanthem 86
Stevens–Johnson syndrome, toxic epidermal necrolysis 86
Drug reaction with eosinophilia and systemic symptoms (DRESS) 86
Acute generalized exanthematous pustulosis (AGEP) 87
Fixed drug eruption 87
Differential diagnosis 87
Management 87
Web resource 87
Associations with malignancy 88
Conditions associated with malignancy 88
Acanthosis nigricans 88
Erythema gyratum repens 88
Necrolytic migratory erythema 88
Paget’s disease and extramammary Paget’s disease 88
Secondary deposits 88
Conditions occasionally associated with malignancy 89
Acquired ichthyosis 89
Generalized pruritus 89
Hyperpigmentation 89
Pyoderma gangrenosum 89
Superficial thrombophlebitis 89
Web resource 89
Inherited disorders 90
Keratinization and blistering syndromes 90
The ichthyoses 90
Skin tumours 94
Benign tumours 94
Benign epidermal tumours 94
Seborrhoeic wart (basal cell papilloma) 94
Special topics in dermatology 105
Ultraviolet radiation and the skin 106
The electromagnetic radiation spectrum 106
Effects of light on normal skin 106
Physiological 106
Sunburn 106
Sunbeds 106
Phototherapy and photochemotherapy 106
Ultraviolet B 106
Photochemotherapy (PUVA) 107
Photoageing 107
Management of photoageing 107
Web resource 107
Cosmetics 108
The range of cosmetics and their usage 108
Constituents of cosmetics 108
Para-phenylenediamine (PPD) hair dye 108
Nail preparations 108
Sunscreens 108
Camouflage cosmetics 108
Skin-lightening creams 108
Hypoallergenic formulations 108
Reactions to cosmetics 108
Irritant contact dermatitis 108
Allergic contact dermatitis 109
Contact urticaria and other adverse reactions 109
Management of cosmetic reactions 109
Web resource 109
Basic dermatological surgery 110
Instruments and methods 110
Basic surgical techniques 110
Excisional biopsy 110
Incisional, punch and shave biopsies 111
Curettage 111
Other surgical techniques 111
Cautery 111
Cryotherapy 111
Web resource 111
Advanced dermatological surgery 112
Simple plastic repairs 112
Skin flaps 112
Skin grafts 112
Mohs’ micrographic surgery 112
Lasers and intense pulsed light (IPL) 112
Photodynamic therapy 113
Cosmetic procedures 113
Web resource 113
New trends in dermatological treatment 114
Atopic eczema 114
Bullous diseases 114
Cutaneous T cell lymphoma 114
Erythema nodosum 114
Fungal infections 114
Hand dermatitis 114
Hidradenitis suppurativa 114
Hyperhidrosis 114
Leg ulcers 114
Psoriasis 115
Scabies 115
Scleroderma 115
Skin cancer 115
Toxic epidermal necrolysis 115
Vitiligo 115
Web resource 115
Paediatric dermatology 116
Childhood eczemas and related disorders 116
Napkin (diaper) dermatitis 116
Infantile seborrhoeic eczema 116
Candidiasis 116
Juvenile plantar dermatosis 116
Other childhood dermatoses 116
Urticaria pigmentosa 116
Langerhans cell histiocytosis (histiocytosis X) 117
Vascular naevi 117
Clinical presentation 117
Salmon patch 117
Port wine stain naevus 117
Infantile haemangioma 117
Arteriovenous malformation (AVM) 117
Management 117
Web resource 117
The skin in old age 118
Intrinsic ageing of the skin 118
Dermatoses in the elderly 118
Dry skin and asteatotic eczema 118
Pruritus 118
Psoriasis 118
Infections and infestations 118
Photodamage and skin tumours 118
Ulceration 119
Web resource 119
Genitourinary medicine 120
Syphilis (lues) 120
Index 134
A 134
B 134
C 134
D 135
E 135
F 135
G 136
H 136
I 136
J 136
K 136
L 136
M 137
N 137
O 137
P 137
R 138
S 138
T 139
U 139
V 139
W 139
X 139
Y 139
Z 139