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Book Details
Abstract
Prevalence of allergic diseases has increased several folds in western world over the last two decades, and similar trend is being observed recently in India. There have been several postulations to explain increasing occurrence of allergic diseases. "Allergic march" refers to sequence of events that starts during fetal life as a result of sensitization to foods and may manifest as eczema, gastrointestinal symptoms, asthma, or hay fever, or combinations of any of these symptoms. A link between genetics and immunology is hypothesized that results in such allergic diseases.
Table of Contents
| Section Title | Page | Action | Price |
|---|---|---|---|
| Front Cover\r | Front Cover | ||
| Front Matter\r | ia | ||
| Copyright | id | ||
| ECAB Clinical Update:Pediatrics | ie | ||
| Contributors | ie | ||
| About the Authors | if | ||
| Contents | ih | ||
| ECAB Clinical Update InformationALLERGY AND ASTHMA | i | ||
| ELSEVIER CLINICAL ADVISORY BOARD (ECAB)INDIA | i | ||
| STATEMENT OF NEED | i | ||
| ALLERGY AND ASTHMA | ii | ||
| TARGET AUDIENCE | ii | ||
| EDUCATIONAL OBJECTIVES | ii | ||
| DISCLAIMER | ii | ||
| DISCLOSURE OF UNLABELED USES | ii | ||
| DISCLOSURE OF FINANCIAL RELATIONSHIPSWITH ANY COMMERCIAL INTEREST | iii | ||
| RESOLUTION OF CONFLICT OF INTEREST | iii | ||
| CONTENT DEVELOPMENT COMMITTEE | iii | ||
| ENQUIRIES | iv | ||
| Preface | v | ||
| Food Allergy in Children | 1a | ||
| Classification of Food Allergy | 2 | ||
| IgE-Mediated Reactions | 2 | ||
| Non-IgE Mediated Reactions | 3 | ||
| Nonallergic Hypersensitivity | 4 | ||
| Prevalence of Food Allergy | 4 | ||
| Common Allergenic Food Items | 4 | ||
| Relation of Food Allergy to Specific Diseases | 6 | ||
| Methods of Evaluation of Food Allergy | 7 | ||
| Therapy for Food Allergy Disorders | 9 | ||
| Prevention | 9 | ||
| Other Exampes of Food Allergy or Intolerance | 10 | ||
| Case Studies Food Allergy in Children | 13 | ||
| IgE-Mediated Anaphylaxis Due to Cow'S Milk | 13 | ||
| Probable Igg-Mediated Allergic Alveolitis | 14 | ||
| Non-Ige-Mediated Eosinophilic Gastroenteritis | 15 | ||
| T-Cell Mediated Celiac Disease | 15 | ||
| Recurrent and Persistent Wheezing in Young Children | 17a | ||
| Significance of Wheezing \"Phenotypes | 18 | ||
| Is Recurrent Wheezing in Early Childhood Related to Asthma in Later Life? | 22 | ||
| Management Issues | 24 | ||
| Clinical Evaluation | 24 | ||
| Investigations | 24 | ||
| Treatment | 25 | ||
| Bronchodilators | 25 | ||
| Anticholinergic Drugs | 25 | ||
| Inhaled Corticosteroids | 26 | ||
| Conclusion | 26 | ||
| Acute Asthma: Advances in\rManagement | 29a | ||
| Global Update | 30 | ||
| Update in Indian Context | 30 | ||
| Pathophysiology | 31 | ||
| Clinical Presentation and Assessment2,3,6,9 | 31 | ||
| Management of Acute Severe Asthma | 34 | ||
| Pharmacotherapy | 34 | ||
| Short-Acting 2-agonists | 34 | ||
| Anticholinergics | 36 | ||
| Corticosteroids | 36 | ||
| Magnesium Sulfate | 36 | ||
| Methylxanthines | 37 | ||
| Systemic Epinephrine and Terbutaline | 37 | ||
| Nonstandard Therapies | 37 | ||
| Nonpharmacologic Management | 38 | ||
| Noninvasive Mechanical Ventilation | 38 | ||
| Mechanical Ventilation | 38 | ||
| Summary (Table 4) | 39 | ||
| In Mild Exacerbation | 40 | ||
| In Moderate Exacerbation | 40 | ||
| In Severe Exacerbation | 41 | ||
| Follow-up2,6 | 41 | ||
| Conclusion | 41 | ||
| Case Studies Acute Asthma: Advances in Management | 43 | ||
| Case Study 1 | 43 | ||
| Long-Term Management of Asthma | 45a | ||
| Management | 46 | ||
| Identification and Elimination of Exacerbating Factors | 47 | ||
| Pharmacotherapy | 50 | ||
| Bronchodilators | 48 | ||
| Corticosteroids | 49 | ||
| Mast-Cell Stabilizers | 53 | ||
| Leukotriene Modifiers | 53 | ||
| Theophylline | 53 | ||
| Steps in the Pharmacological Management | 54 | ||
| Education of Parents | 60 | ||
| Exercise-Induced Bronchoconstriction | 60 | ||
| Seasonal Asthma | 62 | ||
| Home Treatment of Acute Exacerbation | 62 | ||
| Immunotherapy in Children | 69a | ||
| Immune System Development and Hygiene Hypothesis | 70 | ||
| Global Update | 71 | ||
| Update in Indian Context | 72 | ||
| Clinical Experience | 72 | ||
| Allergic Rhinitis and Asthma | 72 | ||
| Anaphylactic Reactions | 73 | ||
| Principles of Immunotherapy | 74 | ||
| Contraindications for Immunotherapy | 74 | ||
| Factors to Consider Before Commencing Allergen Immunotherapy7,8 | 74 | ||
| Mechanisms of Action | 75 | ||
| The Immunologic Effects of Immunotherapy on the Allergic Response | 75 | ||
| Allergic Response | 75 | ||
| Immunologic Effects of Immunotherapy | 75 | ||
| Types of Immunotherapy | 76 | ||
| Conventional Immunotherapy | 76 | ||
| Optimal Dose Immunotherapy | 77 | ||
| Pre-seasonal Method | 77 | ||
| Perennial Method | 77 | ||
| How to Manage Pitfalls?8,13-15 | 78 | ||
| Rush Immunotherapy7 | 79 | ||
| Bee-Venom Immunotherapy | 79 | ||
| Oral Immunotherapy | 79 | ||
| Sublingual Swallow and Spit Therapy | 79 | ||
| Intranasal Immunotherapy | 80 | ||
| Inappropriate Immunotherapy | 81 | ||
| When to Discontinue Immunotherapy | 81 | ||
| Choice of Allergens for Immunotherapy | 82 | ||
| Allergen Extract | 82 | ||
| Aqueous Extracts (e.g., Weeds, Grass Pollen) | 82 | ||
| Depot Extracts | 82 | ||
| Standardization and Storage | 83 | ||
| Reactions of Immunotherapy | 83 | ||
| Outcome And Benefits Of Successful Immunotherapy | 85 | ||
| The Future | 86 | ||
| Conclusion | 86 | ||
| Case Studies Immunotherapy in Children | 94 | ||
| Case Study 1 | 94 | ||
| Case Study 2 | 94 | ||
| Summary | 96 | ||
| Other Books in this Series | 98 |