BOOK
Innovations in Fetal and Neonatal Surgery, An Issue of Clinics in Perinatology - E-Book
Hanmin Lee | Ronald B. Hirschl
(2012)
Additional Information
Book Details
Abstract
The Guest Editors have assembled a list of topics that provide state-of-the-art coverage on fetal surgery. Topics covered include fetal cardiac intervention, abdominal wall defects, NEC, esophageal atresia, and spinia bifida. Some articles provide the clinical basics, like general concepts of fetal surgery, while others provide a detailed look at CDH in utero, CDH post natal, ECMO/placenta, stem cell, and anorectal malformations.
Table of Contents
| Section Title | Page | Action | Price |
|---|---|---|---|
| Front Cover | Cover | ||
| Clinics in Perinatology | i | ||
| Copyright Page | ii | ||
| Contributors | iii | ||
| Table of Contents | vii | ||
| Foreword: The Surgical Neonate: We Need to Track Outcomes | xiii | ||
| Preface | xv | ||
| Chapter 1. Maternal-Fetal Surgery:\r History and General Considerations | 269 | ||
| INTRODUCTION | 269 | ||
| LAYING THE FOUNDATION | 270 | ||
| ENABLING FACTORS | 270 | ||
| ANIMAL MODELS | 271 | ||
| THE EARLY DAYS: UCSF AND BEYOND | 271 | ||
| FETAL SURGERY MATURES: TRIALS AND TRIBULATIONS | 272 | ||
| CONSIDERATIONS IN A FETAL TREATMENT PROGRAM | 275 | ||
| SUMMARY | 277 | ||
| REFERENCES | 277 | ||
| Chapter 2. Fetal Surgery for Myelomeningocele | 279 | ||
| BACKGROUND | 279 | ||
| RATIONALE FOR FETAL REPAIR OF MMC | 280 | ||
| ANIMAL MODELS | 280 | ||
| EARLY HUMAN EXPERIENCE | 281 | ||
| THE MANAGEMENT OF MYELOMENINGOCELE STUDY | 283 | ||
| NEW DIRECTIONS | 283 | ||
| SUMMARY | 285 | ||
| REFERENCES | 285 | ||
| Chapter 3. Advances in Prenatal Diagnosis and Treatment of Congenital Diaphragmatic Hernia | 289 | ||
| INTRODUCTION | 289 | ||
| REVERSING CDH-INDUCED LUNG HYPOPLASIA | 292 | ||
| OPEN REPAIR IN HUMANS | 293 | ||
| RANDOMIZED CONTROLLED TRIAL FOR FETAL TRACHEAL OCCLUSION | 296 | ||
| TRACHEAL OCCLUSION: THE EUROPEAN EXPERIENCE | 296 | ||
| FUTURE DIRECTIONS FOR TRACHEAL OCCLUSION | 297 | ||
| SUMMARY | 297 | ||
| REFERENCES | 297 | ||
| Chapter 4. In Utero Hematopoietic Cell Transplantation for the Treatment of Congenital Anomalies | 301 | ||
| INTRODUCTION | 301 | ||
| THERAPEUTIC RATIONALE | 302 | ||
| ANIMAL EXPERIENCE WITH IUHCTx | 303 | ||
| HUMAN CLINICAL EXPERIENCE | 304 | ||
| FACTORS LIMITING ENGRAFTMENT AFTER IUHCTx | 305 | ||
| COMPLICATIONS | 306 | ||
| FUTURE DIRECTIONS | 306 | ||
| REFERENCES | 306 | ||
| Chapter 5. Advances in Neonatal Extracorporeal Support: The Role of Extracorporeal Membrane Oxygenation and the Artificial Placenta | 311 | ||
| PROGRESS IN PERINATAL/NEONATAL EXTRACORPOREAL MEMBRANE OXYGENATION | 312 | ||
| NOVEL USES OF ECMO | 317 | ||
| ARTIFICIAL PLACENTA | 319 | ||
| REFERENCES | 323 | ||
| Chapter 6. Congenital Lung Lesions | 331 | ||
| PRENATAL DIAGNOSIS AND TREATMENT | 331 | ||
| POSTNATAL CLASSIFICATION OF CLLs | 334 | ||
| CLLs AND MALIGNANCY | 337 | ||
| POSTNATAL MANAGEMENT | 337 | ||
| SUMMARY | 341 | ||
| REFERENCES | 341 | ||
| Chapter 7. Surgical Advances in the Fetus and Neonate: Esophageal Atresia | 349 | ||
| EMBRYOLOGY | 350 | ||
| PRENATAL DIAGNOSIS | 350 | ||
| SHORT-GAP ATRESIA | 352 | ||
| LONG-GAP ATRESIA | 354 | ||
| SUMMARY | 358 | ||
| REFERENCES | 359 | ||
| Chapter 8. Innovations in the Surgical Management of Congenital Diaphragmatic Hernia | 363 | ||
| OBJECTIVES | 363 | ||
| INTRODUCTION | 363 | ||
| SURGICAL APPROACH | 364 | ||
| DIAPHRAGMATIC REPLACEMENTS | 365 | ||
| RISK STRATIFICATION FOR CDH | 369 | ||
| SUMMARY | 370 | ||
| REFERENCES | 370 | ||
| Chapter 9. Advances in Surgery for Abdominal Wall Defects: Gastroschisis and Omphalocele | 375 | ||
| OMPHALOCELE | 375 | ||
| GASTROSCHISIS | 379 | ||
| SUMMARY | 382 | ||
| REFERENCES | 382 | ||
| Chapter 10. Necrotizing Enterocolitis | 387 | ||
| INTRODUCTION | 387 | ||
| EPIDEMIOLOGY | 387 | ||
| PATHOGENESIS | 389 | ||
| DIFFERENTIAL DIAGNOSIS | 392 | ||
| TREATMENT | 392 | ||
| POSTOPERATIVE CARE AND SHORT-TERM OUTCOMES | 394 | ||
| PROGNOSIS/LONG-TERM OUTCOMES | 395 | ||
| PREVENTION | 396 | ||
| FUTURE DIRECTIONS | 397 | ||
| SUMMARY | 397 | ||
| REFERENCES | 397 | ||
| Chapter 11. Anorectal Malformations | 403 | ||
| HISTORY | 403 | ||
| EPIDEMIOLOGY | 404 | ||
| EMBRYOLOGY | 404 | ||
| GENETICS | 404 | ||
| DIAGNOSIS AND WORKUP | 405 | ||
| LESIONS IN THE MALE | 410 | ||
| LESIONS IN THE FEMALE | 415 | ||
| COMPLICATIONS AND LONG-TERM PROBLEMS | 419 | ||
| SUMMARY | 420 | ||
| REFERENCES | 420 | ||
| Index | 423 |