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Update in Gynecologic Oncology, An Issue of Obstetrics and Gynecology Clinics - E-Book

Update in Gynecologic Oncology, An Issue of Obstetrics and Gynecology Clinics - E-Book

Carolyn Y. Muller

(2012)

Additional Information

Book Details

Abstract

This issue of the Obstetrics and Gynecology Clinics provides an update in Gynecologic Oncology.  Vulvar/Vaginal, cervical, uterine, and ovarian cancer are all covered, along with early detection and screening, and genetics and hereditary risk.  There is also an article on trends in cancer care in North America, which discusses cancer care and cost and sustainability as well as practice evloution.

Table of Contents

Section Title Page Action Price
Front Cover Cover
Obstetrics and Gynecology Clinics of North America i
Copyright Page ii
Table of Contents vii
Contributors v
Foreword: Gynecologic Oncology xiii
Preface xv
Chapter 1. Trends in Gynecologic Cancer Care in North America 107
NORTH AMERICAN HEALTH CARE SYSTEMS: CONTEXTUALIZING CANCER CARE 107
QUALITY OF CARE 109
METHODS 109
RESULTS 110
SUMMARY 122
ACKNOWLEDGMENTS 124
REFERENCES 124
Chapter 2. Biologic Therapies and Personalized Medicine in Gynecologic Malignancies 131
CELL SIGNALING PATHWAYS 132
HOMOLOGOUS RECOMBINATION PATHWAYS 134
OTHER MOLECULAR TARGETS OF INTEREST 135
ANTIANGIOGENESIS AGENTS 136
SUMMARY 140
REFERENCES 140
Chapter 3. Advances in Surgical Care 145
HISTORICAL PERSPECTIVE 145
UTERINE CANCER 146
CERVICAL CANCER 157
OVARIAN CANCER 158
ROBOTIC-ASSISTED SURGERY IN GYNECOLOGIC ONCOLOGY 159
VULVAR CANCER 160
SUMMARY 162
REFERENCES 162
Chapter 4. Hereditary Gynecologic Cancers: Risk Assessment, Counseling, Testing and Management 165
OVARIAN CANCER 165
ENDOMETRIAL CANCER 166
HEREDITARY BREAST/OVARIAN CANCER SYNDROME 166
THE LYNCH SYNDROME 170
RARE SYNDROMES THAT INCREASE THE RISK OF GYNECOLOGIC MALIGNANCY 173
GENETIC RISK EVALUATION AND COUNSELING IN HEREDITARY GYNECOLOGIC CANCERS 173
SUMMARY 174
REFERENCES 174
Chapter 5. Ovarian Cancer: Screening and Early Detection 183
SCREENING 183
DIAGNOSIS 187
SUMMARY 192
REFERENCES 192
Chapter 6. Gestational Trophoblastic Neoplasia 195
PATHOLOGY 196
TUMOR BIOMARKERS 198
DIAGNOSIS AND STAGING 200
PRIMARY TREATMENT 202
METASTATIC DISEASE 205
SURGERY FOR GTN 207
DISCUSSION 207
REFERENCES 208
Chapter 7. Vulvar and Vaginal Cancer 213
VULVAR CANCER 213
VAGINAL CANCER 222
SUMMARY 226
REFERENCES 226
Chapter 8. Cervical Cancer 233
EPIDEMIOLOGY 234
RISK FACTORS 234
SCREENING AND PREVENTION 235
PATHOPHYSIOLOGY 235
HISTOLOGIC SUBTYPES 236
DIAGNOSIS 237
TREATMENT 240
SURVEILLANCE 245
RECURRENT CERVICAL CANCER DISEASE 245
PALLIATIVE CARE 247
MANAGEMENT DURING PREGNANCY 247
INVASIVE CERVICAL CANCER FOUND AFTER SIMPLE HYSTERECTOMY 248
SUMMARY 248
REFERENCES 248
Chapter 9. Endometrial Cancer 255
DIAGNOSIS 256
STAGING 256
SURGICAL PROCEDURE FOR ENDOMETRIAL CANCER 257
RISK STRATIFICATION AND ADJUVANT THERAPY 258
CHEMOTHERAPY 258
MOLECULAR THERAPIES FOR ENDOMETRIAL CANCER 259
SUMMARY 264
CLINICAL UPDATE 264
REFERENCES 264
Chapter 10. Epithelial Ovarian Cancer 269
PATHOLOGY AND STAGING 269
CAUSES 270
SCREENING 270
CLINICAL PRESENTATION 271
ADJUVANT TREATMENT 274
NEW MOLECULAR TARGETED THERAPY 277
POSTTREATMENT SURVEILLANCE 277
RECURRENCE 277
REFERENCES 279
Chapter 11. What is Integrative Oncology and Can It Help My Patients? 285
WHY DOES QUALITY OF LIFE MATTER AND HOW CAN I IMPROVE IT? 289
WHO IS USING INTEGRATIVE MODALITIES, WHAT ARE THEY USING, AND ARE THEY SAFE? 290
WHAT INTEGRATIVE APPROACHES ARE THERE EVIDENCE FOR? LIFESTYLE MODIFICATION: DIET, EXERCISE, AND STRESS MANAGEMENT 294
WHAT INTEGRATIVE APPROACHES ARE THERE EVIDENCE FOR? SYMPTOM MANAGEMENT 300
SUMMARY 304
REFERENCES 305
Index 313