BOOK
Breast Pathology: Diagnosis and Insights, An Issue of Surgical Pathology Clinics - E-Book
Stuart J. Schnitt | Sandra J. Shin
(2012)
Additional Information
Book Details
Abstract
Clinically accessible information for pathologists on histology, molecular pathology, differential diagnosis, and clinical overview is presented. Common and rare entities are covered with an abundance of images to highight key features.
Topics for pathologists covering the fast moving field of breast pathology include: Less common variants and mimics of DCIS; Invasive lobular carcinoma and its variants; Important inflammatory and reactive lesions; Small glandular proliferations; Vascular lesions of the breast; Combined epithelial-myoepithelial lesion; Immunhistochemical pitfalls in the diagnosis of breast lesions; Pathology considerations in patients treated with neoadjuvant chemotherapy; Molecular classification of breast cancer: Jorge Reis-Filho; Prognostic factors for patients with breast cancer: Traditional and New
Table of Contents
| Section Title | Page | Action | Price |
|---|---|---|---|
| Front Cover | Cover | ||
| Breast Pathology: Diagnosis\rand Insights | i | ||
| Copyright Page | ii | ||
| Table of Contents | v | ||
| Contributors | iii | ||
| Preface: Breast Pathology: Diagnostic Dilemmas | ix | ||
| CHAPTER 1. LESS COMMON VARIANTS AND MIMICS OF DCIS | 529 | ||
| ABSTRACT | 529 | ||
| OVERVIEW | 529 | ||
| GROSS FEATURES | 529 | ||
| VARIANTS OF DUCTAL CARCINOMA IN SITU | 530 | ||
| SUMMARY | 542 | ||
| REFERENCES | 543 | ||
| CHAPTER 2. INVASIVE LOBULAR CARCINOMA OF THE BREAST | 545 | ||
| ABSTRACT | 545 | ||
| OVERVIEW | 545 | ||
| DIAGNOSIS OF INVASIVE LOBULAR CARCINOMA | 545 | ||
| MICROSCOPIC FEATURES OF INVASIVE LOBULAR CARCINOMA | 546 | ||
| DIFFERENTIAL DIAGNOSIS | 546 | ||
| DIFFERENTIAL DIAGNOSIS - E-CADHERIN | 549 | ||
| DIFFERENTIAL DIAGNOSIS—OTHER PITFALLS | 555 | ||
| OTHER BIOMARKERS | 558 | ||
| STAGING AND PROGNOSIS | 560 | ||
| TREATMENT OF INVASIVE LOBULAR CARCINOMA | 562 | ||
| SUMMARY | 565 | ||
| REFERENCES | 565 | ||
| CHAPTER 3. IMPORTANT INFLAMMATORY AND REACTIVE LESIONS OF THE BREAST | 567 | ||
| ABSTRACT | 567 | ||
| MAMMARY DUCT ECTASIA (PERIDUCTAL MASTITIS) | 567 | ||
| LYMPHOCYTIC MASTOPATHY/DIABETIC MASTOPATHY | 571 | ||
| GRANULOMATOUS LESIONS | 574 | ||
| IGG4-RELATED SCLEROSING MASTITIS | 582 | ||
| EOSINOPHILIC MASTITIS | 582 | ||
| REACTIVE SPINDLE CELL NODULES | 582 | ||
| INFLAMMATORY MYOFIBROBLASTIC TUMOR | 582 | ||
| REACTIONS TO FOREIGN MATERIAL | 582 | ||
| TREATMENT EFFECTS | 586 | ||
| MIMICS OF INFLAMMATORY AND REACTIVE LESIONS | 588 | ||
| REFERENCES | 589 | ||
| CHAPTER 4. SMALL GLANDULAR PROLIFERATIONS OF THE BREAST | 591 | ||
| ABSTRACT | 591 | ||
| OVERVIEW | 591 | ||
| SCLEROSING ADENOSIS | 591 | ||
| RADIAL SCAR | 601 | ||
| TUBULAR CARCINOMA | 606 | ||
| MICROGLANDULAR ADENOSIS | 614 | ||
| LOW-GRADE ADENOSQUAMOUS CARCINOMA | 620 | ||
| SYRINGOMATOUS ADENOMA | 628 | ||
| EPITHELIAL DISPLACEMENT BY NEEDLING PROCEDURES | 633 | ||
| SUMMARY | 638 | ||
| REFERENCES | 638 | ||
| CHAPTER 5. VASCULAR LESIONS OF THE BREAST | 645 | ||
| ABSTRACT | 645 | ||
| ANGIOLIPOMA | 645 | ||
| PERILOBULAR HEMANGIOMA | 647 | ||
| HEMANGIOMA | 648 | ||
| CUTANEOUS ATYPICAL VASCULAR LESIONS | 651 | ||
| RADIATION-ASSOCIATED CUTANEOUS ANGIOSARCOMA | 652 | ||
| PRIMARY ANGIOSARCOMA | 655 | ||
| REFERENCES | 658 | ||
| CHAPTER 6. COMBINED EPITHELIAL- MYOEPITHELIAL LESIONS OF THE BREAST | 661 | ||
| ABSTRACT | 661 | ||
| OVERVIEW | 661 | ||
| ADENOSIS AND ADENOMYOEPITHELIAL ADENOSIS | 661 | ||
| ADENOSIS NODULE | 664 | ||
| COLLAGENOUS SPHERULOSIS | 665 | ||
| ADENOMYOEPITHELIOMA | 668 | ||
| ADENOMYOEPITHELIOMA WITH MALIGNANT PROGRESSION | 676 | ||
| PLEOMORPHIC ADENOMA (MIXED TUMOR OF THE BREAST) | 680 | ||
| PLEOMORPHIC ADENOMA WITH MALIGNANT PROGRESSION | 683 | ||
| ADENOID CYSTIC CARCINOMA | 686 | ||
| REFERENCES | 694 | ||
| CHAPTER 7. MOLECULAR CLASSIFICATION OF BREAST CANCER | 701 | ||
| ABSTRACT | 701 | ||
| OVERVIEW | 701 | ||
| MOLECULAR SUBTYPES OF BREAST CANCER | 702 | ||
| LIMITATIONS OF THE INTRINSIC SUBTYPE CLASSIFICATION | 706 | ||
| INTRINSIC CLASSIFICATION MAY NOT INCLUDE ALL BREAST CANCERS | 707 | ||
| INTRINSIC CLASSIFICATION CANNOT CLASSIFY INDIVIDUAL SAMPLES | 707 | ||
| GENE EXPRESSION PROFILING PROGNOSTIC ASSAYS | 708 | ||
| FIRST-GENERATION PROGNOSTIC GENE SIGNATURES: ARE THEY READY FOR CLINICAL PRACTICE? | 711 | ||
| PREDICTIVE SIGNATURES | 712 | ||
| SUMMARY | 713 | ||
| REFERENCES | 713 | ||
| CHAPTER 8. METASTASES TO AND FROM THE BREAST | 719 | ||
| ABSTRACT | 719 | ||
| OVERVIEW | 719 | ||
| REFERENCES | 741 | ||
| CHAPTER 9. PATHOLOGY CONSIDERATIONS IN PATIENTS TREATED WITH NEOADJUVANT CHEMOTHERAPY | 749 | ||
| ABSTRACT | 749 | ||
| OVERVIEW | 749 | ||
| EVALUATION OF PRETREATMENT CORE NEEDLE BIOPSIES | 751 | ||
| EVALUATION OF POST-TREATMENT SPECIMENS | 752 | ||
| SYSTEMS FOR EVALUATING DEGREE OF RESPONSE TO NAT | 767 | ||
| REPORTING POST-TREATMENT SPECIMENS | 770 | ||
| REFERENCES | 771 | ||
| CHAPTER 10. PROGNOSTIC FACTORS FOR PATIENTS WITH BREAST CANCER: TRADITIONAL AND NEW | 775 | ||
| ABSTRACT | 775 | ||
| OVERVIEW | 775 | ||
| SUMMARY | 782 | ||
| REFERENCES | 783 | ||
| Index | 787 |