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Cartilage Injuries in the Pediatric Knee, An Issue of Orthopedic Clinics - E-Book

Cartilage Injuries in the Pediatric Knee, An Issue of Orthopedic Clinics - E-Book

Harpal Gahunia | Paul Babyn

(2012)

Additional Information

Book Details

Abstract

This Clinics issue will encompass the following topics pertaining to articular cartilage:structure, biochemistry, biomechanics, function, injury, degeneration, repair, cartilage-engineering strategies, and other treatment options.

Table of Contents

Section Title Page Action Price
Front Cover Cover
Orthopedic Clinics of North America i
Copyright Page ii
Contributors iii
Table of Contents v
Preface ix
Chapter 1. Articular Cartilage Development: A Molecular Perspective 155
STRUCTURE AND FUNCTION OF ARTICULAR CARTILAGE 155
ARTICULAR-EPIPHYSEAL CARTILAGE (IMMATURE) 156
ARTICULAR CARTILAGE (MATURE) 157
CHONDROGENESIS 158
ENDOCHONDRAL OSSIFICATION 162
CARTILAGE MATRIX MODELING DURING ENDOCHONDRAL OSSIFICATION 165
SUMMARY 167
REFERENCES 167
Chapter 2. Structural and Functional Maturation of Distal Femoral Cartilage and Bone During Postnatal Development and Growth in Humans and Mice 173
MATERIALS AND METHODS 174
RESULTS 176
DISCUSSION 180
REFERENCES 183
Chapter 3. Effect of Exercise on Articular Cartilage 187
ARTICULAR CARTILAGE 188
CHONDRONS 188
CARTILAGE EXTRACELLULAR MATRIX 188
ARTICULAR CARTILAGE COLLAGENS 188
PROTEOGLYCANS 189
NONCOLLAGENOUS PROTEINS 189
CARTILAGE MATRIX COMPARTMENTALIZATION 190
AGING OF ARTICULAR CARTILAGE 190
EFFECT OF PHYSICAL ACTIVITY ON ARTICULAR CARTILAGE AND ADJACENT TISSUES 191
JOINT ARTHROPATHY AND EFFECT OF EXERCISE 192
CARTILAGE-STRENGTHENING PHYSICAL ACTIVITY 193
SUMMARY 194
REFERENCES 194
Chapter 4. Imaging of Osteochondritis Dissecans 201
CLINICAL PRESENTATION 201
IMAGING WORK-UP 202
TREATMENT OF OCD 206
IMAGING TO ASSESS HEALING 207
SUMMARY 209
REFERENCES 209
Chapter 5. Epidemiology, Pathogenesis, and Imaging of Arthritis in Children 213
EPIDEMIOLOGY 213
CLASSIFICATION 213
PATHOGENESIS 215
IMAGING EVALUATION AND SPECTRUM OF IMAGING FINDINGS 216
SUMMARY 223
REFERENCES 224
Chapter 6. Acute Traumatic and Sports-Related Osteochondral Injury of the Pediatric Knee 227
BACKGROUND AND MECHANISM OF OC FRACTURE DURING PATELLAR DISLOCATION 227
CLINICAL PRESENTATION AND DIAGNOSIS 228
MANAGEMENT AND SURGICAL TECHNIQUE 229
REDUCTION AND REPAIR OF OC FRACTURES 230
RESULTS 231
MANAGEMENT OF POSTTRAUMATIC KNEE HEMARTHROSIS 232
SUMMARY 233
REFERENCES 233
Chapter 7. “One Step” Treatment of Juvenile Osteochondritis Dissecans in the Knee: Clinical Results and T2 Mapping Characterization 237
MATERIALS AND METHODS 238
PATIENTS 238
CLINICAL EVALUATION 238
MRI EVALUATION 238
STATISTICAL ANALYSIS 239
SURGICAL TECHNIQUE 239
RESULTS 241
DISCUSSION 242
REFERENCES 243
Chapter 8. Clinical Relevance of Scaffolds for Cartilage Engineering 245
NONOPERATIVE THERAPY 246
NONREPARATIVE/NONRESTORATIVE PROCEDURES 246
REPAIR/BONE MARROW–STIMULATING TECHNIQUES 246
RESTORATIVE TECHNIQUES 247
TISSUE ENGINEERING/SCAFFOLDS 248
SUMMARY 251
REFERENCES 251
Chapter 9. Implantation of Orthobiologic, Biodegradable Scaffolds in Osteochondral Repair 255
MACI 256
HYALURONAN-BASED SCAFFOLDS 257
TISSUE ENGINEERED COLLAGEN SCAFFOLDS WITH MECHANICAL STIMULATION 258
SUMMARY 258
REFERENCES 259
Index 263