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Chronic Diarrhea, An Issue of Gastroenterology Clinics - E-Book

Chronic Diarrhea, An Issue of Gastroenterology Clinics - E-Book

Heinz F. Hammer

(2012)

Additional Information

Abstract

Dr. Hammer has assembled a international list of authors who fully update the topic of chronic diarrhea, from examining the causes of diarrhea (and the appropriate treatments) to various diagnostic tools. Among the topics covered are bacterial flora as a cause or treatment, the value of fecal analysis in the evaluation, circulating secretagogues, functional diarrhea, celiac disease, chronic inflammatory diseases, diarrhea as a symptom of food intolerance, immunosuppression and immune-deficiency, and chronic diarrhea in the developing world.

Table of Contents

Section Title Page Action Price
Front Cover Cover
Gastroenterology Clinics of North America: Chronic Diarrhea i
Copyright Page ii
Table of Contents v
Contributors iii
Preface Chronic Diarrheal Disorders ix
Chapter 1. The Practical Value of Comprehensive Stool Analysis in Detecting the Cause of Idiopathic Chronic Diarrhea 539
INTRODUCTION 539
PRESENT STUDY 541
STOOL COLLECTION, METHODS OF ANALYSIS, AND INTERPRETATION 541
DEFINITIONS 542
RESULTS AND COMMENTS 547
DISCUSSION AND SUMMARY 557
ACKNOWLEDGMENTS 558
REFERENCES 558
Chapter 2. Colorectal Normal Histology and Histopathologic Findings in Patients with Chronic Diarrhea 561
INTRODUCTION 561
NORMAL HISTOLOGY 562
MICROSCOPIC COLITIS 564
MAST CELL (MASTOCYTIC) ENTEROCOLITIS 568
INFLAMMATORY BOWEL DISEASE 570
SUMMARY 576
REFERENCES 576
Chapter 3. Bacterial Flora as a Cause or Treatment of Chronic Diarrhea 581
INTRODUCTION 581
MUCOSAL BARRIER, GUT MICROBIOTA, AND INTESTINAL HEALTH 582
CHRONIC DIARRHEA AND GUT MICROBIOTA: WHEN INTESTINAL HOMEOSTASIS IS DISTURBED 582
STUDYING GUT MICROBIOTA 584
GUT MICROBIOTA MODULATION 585
GUT MICROBIOTA MODULATION IN CHRONIC DIARRHEA 587
SUMMARY 595
ACKNOWLEDGMENT 596
REFERENCES 596
Chapter 4. Diarrhea Caused By Circulating Agents 603
INTRODUCTION 603
THE CLASSIC ENDOCRINE DIARRHEAL SYNDROME: VERNER-MORRISON SYNDROME OR VIPOMA SYNDROME 604
MALIGNANT CARCINOID SYNDROME 605
ZOLLINGER-ELLISON SYNDROME 606
MEDULLARY CARCINOMA OF THE THYROID 607
SOMATOSTATINOMA SYNDROME 607
SYSTEMIC MASTOCYTOSIS 607
HYPERTHYROIDISM 607
OTHER CAUSES 608
REFERENCES 608
Chapter 5. Diarrhea Caused By Carbohydrate Malabsorption 611
INTRODUCTION 611
METHODS FOR ESTABLISHING THE ROLE OF CARBOHYDRATE MALABSORPTION FOR THE PATHOGENESIS OF DIARRHEA 612
THE ROLE OF THE COLON FOR COLONIC SALVAGE OF MALABSORBED OR INCOMPLETELY ABSORBED CARBOHYDRATES AND GAS PRODUCTION 613
INFLUENCE OF ANTIBIOTICS ON COLONIC CARBOHYDRATE SALVAGE 614
THE ROLE OF COLONIC TRANSIT IN CARBOHYDRATE-INDUCED DIARRHEA 615
DIARRHEA IN CARBOHYDRATE MALABSORPTION—MULTIPLE INFLUENCING FACTORS 616
CARBOHYDRATE MALABSORPTION IN MALABSORPTIVE DISEASES: INNOCENT BYSTANDER OR RELEVANT FOR CALORIE LOSS AND DIARRHEA? 616
DOES CARBOHYDRATE MALABSORPTION CONTRIBUTE TO FECAL ENERGY LOSS IN ROUX-EN-Y GASTRIC BYPASS? 617
LACTASE DEFICIENCY AND LACTOSE MALABSORPTION 618
INCOMPLETE ABSORPTION AND INTOLERANCE OF FRUCTOSE (FRUCTOSE MALABSORPTION) 619
DISACCHARIDASE DEFICIENCIES AND TRANSPORT DEFECTS FOR MONOSACCHARIDES 620
DIAGNOSIS OF CARBOHYDRATE MALABSORPTION 621
SUMMARY 622
REFERENCES 623
Chapter 6. Functional Diarrhea 629
INTRODUCTION AND DEFINITION 629
EPIDEMIOLOGY 630
DIAGNOSTIC APPROACH 630
PATHOPHYSIOLOGIC MECHANISMS IN FUNCTIONAL DIARRHEA 631
TREATMENT APPROACH 631
INTESTINAL TRANSIT INHIBITORS 631
INTRALUMINAL AGENTS 633
PROABSORPTIVE DRUGS: CLONIDINE 634
ANTISECRETORY DRUGS: OCTREOTIDE 634
SUMMARY 634
REFERENCES 634
Chapter 7. Celiac Disease 639
CONTEMPORARY CELIAC DISEASE 639
DIAGNOSIS 641
DIARRHEA IN CELIAC DISEASE 643
SUMMARY 645
REFERENCES 645
Chapter 8. Diarrhea in Chronic Inflammatory Bowel Diseases 651
INTRODUCTION 651
BRIEF REVIEW OF NORMAL INTESTINAL FLUID TRANSPORT 652
MICROSCOPIC COLITIS 652
CLINICAL PRESENTATION 654
DIAGNOSIS 655
TREATMENT OF MICROSCOPIC COLITIS 655
ULCERATIVE COLITIS AND CD 658
CLINICAL PRESENTATION 658
PATHOPHYSIOLOGY OF DIARRHEA 659
INFLAMMATION AND DEFECTIVE INTESTINAL ION TRANSPORT 659
CAUSES OF DIARRHEA OTHER THAN INFLAMMATION RESULTING FROM ACTIVE DISEASE 660
TREATMENT 667
REFERENCES 668
Chapter 9. Diarrhea in the Immunocompromised Patient 677
INTRODUCTION 677
DIARRHEA AS A CONSEQUENCE OF INFECTION WITH HUMAN IMMUNODEFICIENCY VIRUS 679
INFECTIOUS DIARRHEA IN IMMUNOCOMPROMISED PATIENTS 679
PARASITIC INFECTIONS 680
BACTERIAL INFECTIONS 681
VIRAL INFECTIONS 684
FUNGAL INFECTIONS 686
NONINFECTIOUS DIARRHEA IN HIV-INFECTED PATIENTS 687
DIARRHEA AFTER HSCT AND AFTER SOLID ORGAN TRANSPLANTATION 688
DRUG-INDUCED DIARRHEA 690
CONGENITAL IMMUNODEFICIENCY SYNDROMES 691
REFERENCES 692
Index 703