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Skin: Discourse on Emerging Science and Techniques, An Issue of Clinics in Plastic Surgery - E-Book

Skin: Discourse on Emerging Science and Techniques, An Issue of Clinics in Plastic Surgery - E-Book

Richard E. Baxter

(2011)

Additional Information

Book Details

Abstract

Information is presented from international authors in the realm of Biology, Physiology, Basic Science, and Clinical Medicine on aspects of skin of interest to the Plastic Surgeon. Topics range from Skin grafting and the Physiology of aging skin, through Dermal substitutes and Skin tissue engineering.

Table of Contents

Section Title Page Action Price
Front Cover Cover
Skin: Discourse on Emerging Science and Techniques i
Copyright Page ii
Table of Contents v
Contributors iii
Publisher’s Note ix
Chapter 1. Physiology of Skin Aging 1
INTRODUCTION 1
MECHANISMS OF SKIN AGING 1
POSTSYNTHETIC MECHANISMS OF SKIN AGING 3
INHIBITION OF AGE-RELATED HARMFUL EFFECTS 5
DISCUSSION 5
ACKNOWLEDGMENTS 7
REFERENCES 7
Chapter 2. Stiffening of Human Skin Fibroblasts with Age 9
INTRODUCTION 9
MATERIALS AND METHODS 10
RESULTS 12
DISCUSSION 17
SUPPORTING MATERIAL 19
REFERENCES 19
Chapter 3. Tissue Engineering of Skin 21
INTRODUCTION 21
DEVELOPMENT, ANATOMY, AND FUNCTION OF SKIN 22
THE POTENTIAL PREREQUISITE REQUIREMENTS FOR TE SKIN SOLUTIONS 24
CURRENT TE SKIN TECHNOLOGIES 25
TE SKIN SOLUTIONS IN CLINICAL PRACTICE 28
THE FUTURE 29
SUMMARY 29
REFERENCES 30
Chapter 4. Skin Tissue Engineering—In Vivo and In Vitro Applications 33
INTRODUCTION 33
IN VIVO APPLICATIONS 33
IN VITRO APPLICATIONS 40
DISEASE SKIN MODELS 46
CONCLUSIONS 51
ACKNOWLEDGMENTS 51
REFERENCES 51
Chapter 5. Pre- and Probiotics for Human Skin 59
INTRODUCTION 59
MICROFLORA OF HUMAN SKIN 59
PREBIOTICS AND SKIN 61
PROBIOTICS AND SKIN 61
ACKNOWLEDGMENTS 63
REFERENCES 63
Chapter 6. Dermal Substitutes Do Well on Dura: Comparison of Split Skin Grafting + / – Artificial Dermis for Reconstruction of Full-thickness Calvarial Defects 65
CASE REPORT 65
DISCUSSION 66
REFERENCES 67
Chapter 7. Management of Wounds with Exposed Bone Structures using an Artificial Dermis and Skin Grafting Technique 69
CLINICAL MATERIALS AND METHODS 72
FINDINGS AND RESULTS 73
FOLLOW-UP 73
DISCUSSION 73
SUMMARY 75
REFERENCES 75
Chapter 8. Management of Split Skin Graft Donor Sites–Results of a National Survey 77
MATERIALS AND METHODS 77
RESULTS 77
DISCUSSION 81
ACKNOWLEDGMENTS 82
REFERENCES 82
Chapter 9. Skin: Histology and Physiology of Wound Healing 85
SKIN HISTOLOGY 87
AGE IN WOUND HEALING 93
INFECTION IN WOUND HEALING 93
IMMUNE FUNCTION IN WOUND HEALING 94
DIABETES AND WOUND HEALING 94
HYPERTROPHIC SCARRING AND KELOIDS 94
OXYGEN DELIVERY IN WOUND HEALING 94
NUTRITION IN WOUND HEALING 95
SMOKING IN WOUND HEALING 95
RADIATION IN WOUND HEALING 95
CHEMOTHERAPY IN WOUND HEALING 95
FUTURE RESEARCH IN WOUND HEALING 95
REFERENCES 96
Index 99