BOOK
Common Toxicologic Issues in Small Animals, An Issue of Veterinary Clinics: Small Animal Practice - E-Book
Safdar N. Khan | Stephen B. Hooser
(2012)
Additional Information
Book Details
Abstract
A comprehensive review of toxicology for the small animal practitioner! Guest editors Safdar Khan and Stephen Hooser present articles on trends of animal poisoning cases in the USA, use of lipid emulsions, epidemiology of mushroom poisoning cases, toxicology of ADHD drugs, toxicology of human NSAIDS, diagnostic toxicology with emphasis on how to investigate or what to do in food-related outbreaks, toxicology of avermectins (ivermectins, moxidectin, doramectin, selamectin), rodenticides toxicosis, include difethiolone, toxicology of newer pesticides, toxicology of explosives, recently recognized nephrotoxic agents/toxicants, calcium channel blocker toxicosis, adverse effects, and more!
Table of Contents
| Section Title | Page | Action | Price |
|---|---|---|---|
| Front Cover | Cover | ||
| Common Toxicologic\rIssues in Small Animals | i | ||
| Copyright Page | ii | ||
| Contributors | iii | ||
| Table of Contents | v | ||
| Preface | xi | ||
| Chapter 1. An Overview of Trends in Animal Poisoning Cases in the United States: 2002–2010 | 219 | ||
| MATERIALS AND METHODS | 219 | ||
| WHERE AND WHEN EXPOSURES/POISONINGS OCCUR | 219 | ||
| TYPES OF ANIMALS INVOLVED IN POISONING CASES | 221 | ||
| TRENDS IN THE TYPES OF TOXICANTS INVOLVED | 222 | ||
| TRENDS IN THERAPIES | 226 | ||
| SUMMARY | 227 | ||
| REFERENCES | 228 | ||
| Chapter 2. Investigative Diagnostic Toxicology and the Role of the Veterinarian in Pet Food–Related Outbreaks | 229 | ||
| PET FOOD–RELATED OUTBREAKS AND RECALLS | 229 | ||
| THE ROLE OF THE VETERINARIAN AND THE HUMAN ELEMENT | 230 | ||
| ESTABLISHING A CAUSAL RELATIONSHIP BETWEEN CLINICAL SIGNS ANDSUSPECT FOODSTUFFO | 231 | ||
| EFFECTIVE USE OF VETERINARY DIAGNOSTIC LABORATORIES | 232 | ||
| REPORTING A PET FOOD COMPLAINT | 233 | ||
| SUMMARY | 234 | ||
| REFERENCES | 234 | ||
| Chapter 3. Pet Food Recalls and Pet Food Contaminants in Small Animals | 237 | ||
| NATURAL CONTAMINANTS | 239 | ||
| MISFORMULATION | 242 | ||
| ADULTERATION | 245 | ||
| SUMMARY | 247 | ||
| ACKNOWLEDGMENTS | 247 | ||
| REFERENCES | 247 | ||
| Chapter 4. Use of Intravenous Lipid Emulsions for Treating Certain Poisoning Cases in Small Animals | 251 | ||
| BACKGROUND | 251 | ||
| PROPOSED MECHANISMS OF ACTION | 253 | ||
| BEYOND LOCAL ANESTHETIC TOXICOSES | 254 | ||
| CLINICAL APPLICATION OF ILE IN VETERINARY MEDICINE | 258 | ||
| SUMMARY | 259 | ||
| REFERENCES | 260 | ||
| Chapter 5. Calcium Channel Blocker Toxicity in Dogs and Cats | 263 | ||
| PATHOPHYSIOLOGY | 264 | ||
| PHARMACOLOGY | 265 | ||
| CLINICAL SIGNS | 269 | ||
| DIAGNOSIS | 270 | ||
| TREATMENT | 270 | ||
| SUMMARY | 274 | ||
| REFERENCES | 274 | ||
| Chapter 6. Management of Attention-Deficit Disorder and Attention-Deficit/Hyperactivity Disorder Drug Intoxication in Dogs and Cats | 279 | ||
| AMPHETAMINE SALTS AND OTHER SIMILAR AGENTS | 280 | ||
| ATOMOXETINE | 284 | ||
| SUMMARY | 286 | ||
| REFERENCES | 287 | ||
| Chapter 7. Toxicology of Frequently Encountered Nonsteroidal Anti-Inflammatory Drugsin Dogs and Cats | 289 | ||
| GENERAL USES AND CLASSIFICATION | 289 | ||
| INCIDENT DATA | 290 | ||
| GENERAL INFORMATION REGARDING ABSORPTION, DISTRIBUTION, METABOLISM,AND EXCRETION | 291 | ||
| GENERAL MECHANISMS OF ACTIONS | 292 | ||
| PROSTAGLANDINS | 293 | ||
| GENERAL TREATMENT RECOMMENDATIONS FOR ACUTE NSAID OVERDOSE | 295 | ||
| SPECIFIC TOXICITY INFORMATION REGARDING THE TOP 10 MOST FREQUENTLYREPORTED NSAIDS IN DOGS AND CATS | 296 | ||
| REFERENCES | 303 | ||
| Chapter 8. Xylitol Toxicosis in Dogs | 307 | ||
| SOURCES | 307 | ||
| TOXICOKINETICS | 308 | ||
| TOXICITY | 308 | ||
| CLINICAL SIGNS AND LABORATORY CHANGES | 309 | ||
| TREATMENT AND MONITORING | 310 | ||
| SUMMARY | 311 | ||
| REFERENCES | 311 | ||
| Chapter 9. Toxicology of Avermectins and Milbemycins (Macrocylic Lactones) and the Role of P-Glycoprotein in Dogs and Cats | 313 | ||
| CHEMISTRY OF MACROCYCLIC LACTONES | 313 | ||
| MECHANISMS OF TOXICITY AND THE ROLE OF P-GLYCOPROTEIN | 314 | ||
| EXPOSURE SOURCES, FORMULATIONS, AND THERAPEUTIC AND TOXIC DOSAGES | 315 | ||
| TOXICOKINETICS OF MACROCYCLIC LACTONES AND THE ROLE OF P-GLYCOPROTEIN | 320 | ||
| SENSITIVE POPULATIONS | 321 | ||
| TREATMENT | 325 | ||
| DIAGNOSTICS | 328 | ||
| OUTCOME | 328 | ||
| SUMMARY | 328 | ||
| REFERENCES | 329 | ||
| Chapter 10. Toxicology of Newer Insecticides in Small Animals | 335 | ||
| ORGANOPHOSPHATES AND CARBAMATES | 335 | ||
| PYRETHRINS/PYRETHROIDS | 337 | ||
| AVERMECTINS | 339 | ||
| IMIDACLOPRID | 339 | ||
| NITENPYRAM | 340 | ||
| FIPRONIL | 340 | ||
| BORATES | 341 | ||
| HYDRAMETHYLNON | 341 | ||
| SPINOSAD | 342 | ||
| INDOXACARB | 342 | ||
| SULFLURAMID | 343 | ||
| ESSENTIAL OILS | 343 | ||
| LUFENURON | 344 | ||
| METHOPRENE | 344 | ||
| PYRIPROXYFEN | 345 | ||
| SUMMARY | 345 | ||
| REFERENCES | 345 | ||
| Chapter 11. Common RodenticideToxicoses in Small Animals | 349 | ||
| KEYWORDS | 349 | ||
| ANTICOAGULANT RODENTICIDES | 349 | ||
| BROMETHALIN | 352 | ||
| CHOLECALCIFEROL | 355 | ||
| SUMMARY | 359 | ||
| REFERENCES | 359 | ||
| Chapter 12. Toxicology of Explosives and Fireworks in Small Animals | 361 | ||
| KEYWORDS | 361 | ||
| EXPLOSIVES | 361 | ||
| FIREWORKS | 367 | ||
| SUMMARY | 371 | ||
| REFERENCES | 371 | ||
| Chapter 13. Mushroom Poisoning Cases in Dogs and Cats: Diagnosis and Treatment of Hepatotoxic, Neurotoxic, Gastroenterotoxic, Nephrotoxic, and Muscarinic Mushrooms | 375 | ||
| KEYWORDS | 375 | ||
| INCIDENCES | 376 | ||
| HEPATOTOXIC MUSHROOMS | 376 | ||
| NEUROTOXIC MUSHROOMS | 380 | ||
| MUSCARINE-CONTAINING MUSHROOMS | 381 | ||
| MUSHROOMS RESULTING IN GASTROINTESTINAL IRRITATION | 382 | ||
| NEPHROTOXIC MUSHROOMS | 383 | ||
| SUMMARY | 385 | ||
| REFERENCES | 386 | ||
| Chapter 14. Differential Diagnosis of Common Acute Toxicologic Versus Nontoxicologic Illness | 389 | ||
| FURTHER READINGS | 401 | ||
| Chapter 15. Common Reversal Agents/Antidotes in Small Animal Poisoning | 403 | ||
| FURTHER READINGS | 406 | ||
| Index | 407 |