Abstract

The Handbook of Glycomics provides the first comprehensive overview of the emerging field of glycomics, defined as the study of all complex carbohydrates in an organism or cell ("the glycome"). Beginning with analytic approaches and bioinformatics, this work provides a detailed discussion of relevant databases, data integration, and analysis. It then moves on to a discussion of specific model organism and pathogen glycomes followed by therapeutic approaches to human disorders of glycosylization. Structure and function of glycomes are included along with state-of-the-art technologies and systems approaches to the analysis of glycans.

• Synthesizes contributions from experts in biology, chemistry, bioinformatics, biotechnology, and medicine
• Highlights chapters devoted to chemical synthesis, cancer glycomics and immune cell glycomics
• Includes discussions of proteomics, mass spectrometry, NMR, array technology, and transcriptomics analytic approaches

"Overall, this book is well presented; each chapter contains very valuable figures, an up-to-date bibliography, and tables and charts including 22 color plates at the end of the book. The subject index is useful for fast orientation in the numerous topics discussed in the book. A remarkable feature of this book is very wide range of high_ lighting scientific directions that currently unite in glycomics. This book will no doubt serve as an excellent comprehensive overview and will be handy reference book for scientists and teachers in glycobiology, biochemistry, molecular biology, biotechnology, and medicine." --Biochemistry 2010, Volume 75. No. 8, pp. 1064-65