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Handbook of Models for Human Aging

Handbook of Models for Human Aging

P. Michael Conn | Stephen A. Benjamin | Caleb E. Finch | John C. Guerin | James F. Nelson | S. Jay Olshansky | George Roth | Roy G. Smith

(2011)

Abstract

The Handbook of Models for Human Aging is designed as the only comprehensive work available that covers the diversity of aging models currently available. For each animal model, it presents key aspects of biology, nutrition, factors affecting life span, methods of age determination, use in research, and disadvantages/advantes of use. Chapters on comparative models take a broad sweep of age-related diseases, from Alzheimer's to joint disease, cataracts, cancer, and obesity. In addition, there is an historical overview and discussion of model availability, key methods, and ethical issues.

  • Utilizes a multidisciplinary approach
  • Shows tricks and approaches not available in primary publications
  • First volume of its kind to combine both methods of study for human aging and animal models
  • Over 200 illustrations

"Taken all together, this handbook gives an excellent impression of what is done in aging research nowadays, which models are applied for which question and where the limitations of the models are. It covers very broadly standard models as well as more exotic, just emerging modles of aging research. Michael Conn has indeed achieved his goal of creating a comprehensive handbook covering all models of research." --Martina Rauner in WIENER MEDIZINISCHE WOCHENSCHRIFT