Abstract

Since publication of the Third Edition in 1998, the understanding of the immune mechanisms underlying autoimmunity and autoimmune disease has significantly deepened and broadened. This Fourth Edition incorporates new material and combines common themes underlying inductive and effector mechanisms and therapies that relate generally to the autoimmune disorders. It discusses the biological basis of disease at genetic, molecular, cellular, and epidemiologic levels.
New to This Edition:
* Tissue-specific interventions to arrest or "cure" autoimmune disease
* Bone marrow eradication and replacement
* Both basic science and clinical medicine is covered
* Boxed points to emphasize key features of each chapter
"...This thoughtfully updated new edition takes into consideration important developments in basic and clinical science...This book will be a valuable resource..."
- Martha M. Eibl, M.D. for NEW ENGLAND JOURNAL OF MEDICINE (Jan 2006)