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Conjugation-Dependent Carcinogenicity and Toxicity of Foreign Compounds

Conjugation-Dependent Carcinogenicity and Toxicity of Foreign Compounds

J. Thomas August | Ferid Murad | M. W. Anders | Wolfgang Dekant

(1994)

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Book Details

Abstract

Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular basis of drug action, both applied and experimental.
Conjugation reactions have long been associated with the detoxification of xenobiotics. Recent studies suggest that Phase II reactions are an important mechanism for the bioactivation of xenobiotics.
This special volume of Advances in Pharmacology features a two-color dust jacket.

Summarizes the most recent information on:

  • Xenobiotic conjugation
  • Drug toxicity, hypersensitivity, and targeting
  • Chemical carcinogenesis
  • Glutathione-, sulfate conjugate-, and glucuranide conjugate-dependent toxicity
  • Bioactivation and bioconversion

Praise for the Serial
"The book provides superb reading material which chemists and pharmacologists interested in the area of chemotherapy will surely enjoy reading." --JOURNAL OF PHARMACEUTICAL SCIENCES