Abstract

The Vaccine Book provides comprehensive information on the current and future world of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases such as AIDS, tuberculosis, and malaria. The Vaccine Book is designed for students, researchers, public health officials, and all others interested in increasing their understanding of vaccines.
Topics unique to this book:
* Ethics
* Economics
* Diseases that could be prevented
* Clinical trial designs
* Ideas about the future of vaccines
* Challenges facing research scientists in the vaccine area
* Burden of vaccine-preventable illness and the impact of vaccines
* Scientific obstacles to be overcome by existing and new vaccines
* Basic mechanisms of host immunity and pathogen interaction with host tissues
* New approaches to future vaccines against challenging diseases
* Real and perceived safety issues which dominate vaccine development and vaccination policies
* Microbial pathogenesis as a basis for vaccine design
* Planning vaccine trials
* Introducing new vaccines into the healthcare system
* Future challenges for vaccines and immunizations
"...should be a standard reference work for anyone from student to senior professional." (Richard T. Mahoney, Bulletin of the World Health Organization, September 2004)
"...should be a standard reference work for anyone from student to senior professional interested in the current challenges in and propsects for the science of vaccines."
-BULLETIN OF THE WORLD HEALTH ORGANIZATION (2004)
"...provides a thorough review on a wide variety of topics regarding vaccines and immunization."
-E-STREAMS (2003)
"...a useful reference book. ...should appeal to a wide audience, including health economists and strategists, microbiologists and epidemiologists."
-MICROBIOLOGY TODAY (2003)