Abstract

The Practice of Medicinal Chemistry, 2E, is a single-volume source on the practical aspects of medicinal chemistry. The successful first edition was nicknamed "The Bible" by medicinal chemists, and the second edition has been updated, expanded and refocused to reflect developments over the last decade. Emphasis is put on how medicinal chemists conduct their search for and design of new drug entities. In contrast to competing books, it focuses on the chemistry rather than pharmacological concepts or descriptions of the various therapeutic classes of drugs. Most medicinal chemists working in the pharmaceutical industry are organic synthetic chemists who must acquire a strong knowledge of medicinal chemistry as they enter the industry. This book aims to be their practical handbook - a complete guide to the drug discovery process.
* The only book available dealing with the practical aspects of medicinal chemistry
* Serves as a complete guide to the drug discovery process, from conception of the molecules to drug production
* Updated chapters devoted to the discovery of new lead compounds, including combinatorial chemistry
"...it serves as an excellent introduction to those just starting a career in medicinal chemistry."
-John W. Ellingboe, Wyeth Research, New York
"The Practice of Medicinal Chemistry is highly recommended for medical libraries and academic libraries that support a chemistry program."
-E-STREAMS (May 2004)
"...capture[s] the whole spectrum of activities associated with both the theory and practice of rational drug design."
-BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2003)