Abstract

Protein modules engage in a multitude of interactions with one another and with other cellular components, notably with DNA. These interactions are a central aspect of protein function of great relevance in the post-genomic era. This volume describes a panel of approaches for analyzing protein modules and their interactions, ranging from bioinformatics to physical chemistry, to biochemistry, with an emphasis on the structure-function relationship in protein-protein complexes involved in cellular processes including signal transduction.

• Comprehensive overview of different facets of macromolecule interactions
• Computational and bioinformatics aspects of analyzing protein modules and their interactions
• Emphasis on structure-function relationship in protein-protein complexes involved in cellular processes

PRAISE FOR THE SERIES: "The authority, originality, and editing of the reviews are first class." --NATURE

"The Advances in Protein Chemistry series has been a major factor in the education of protein chemists." --JOURNAL OF THE AMERICAN CHEMICAL SOCIETY