This highly practical book, and successor to Volume 13 in the Laboratory Techniques series, explores further and provides more comprehensive, autoritative information on the production of Mabs. Much new and illuminating material has been included covering the concepts behind the application of recombinant DNA technology and biosensor technology to monoclonal antibodies, and all the human Mab technology facilitated by PCR of antibody genes.
Also included in this latest volume is a section focussing on other methods of obtaining B cell clones such as short-term culture and oncogene transformation and an interesting section on Mab patents.
...this is a readable and well-written book that should be of great use to all those involved in the production and use of monoclonal antibodies.
...a clear and detailed account of mAb production, analysis and use, and should be an essential addition to all academic and industrial biotechnology libraries.
Trends in Biotechnology
...essential reading for the would-be immunosensor technologist...also for those considering entering the field of Mab technology.