Abstract

High Throughput Analysis for Early Drug Discovery offers concise and unbiased presentations by synthetic and analytical chemists who have been involved in creating and moving the field of combinatorial chemistry into the academic and industrial mainstream. Since the synthetic method often dictates the appropriate types of analysis, each chapter or section begins with a description of the synthesis approach and its advantages. The description of various combinatorial and high-throughput parallel synthesis techniques provide a relevant point of entry for synthetic chemists who need to set up appropriate characterisation methods for his/her organisation. This is an invaluable resource for all organic and analytical chemists in the pharmaceutical, agrochemical, and biotechnology fields who are either involved in, or beginning to investigate combinatorial techniques to increase overall efficiency and productivity.

• First reference to focus on the analytical side of synthesis

"The volume provides useful information to scientists interested in the topic specially organic and analytical chemists dealing with drug development and discovery and therefore it would be highly recommended."
Hassan Y. Aboul-Enein, Centre for Clinical Research, Saudi Arabia, BIOMEDICAL CHROMATOGRAPHY, 2005
"Overall this book is very informative and meets its goal of enlightening readers about current high-throughput analysis methods used to analyze combinatorial products. "
ANAL BIOANAL CHEM (2006) 385, Sapna Deo, Indiana University, IN, USA