Abstract

This four-volume laboratory manual contains comprehensive state-of-the-art protocols essential for research in the life sciences. Techniques are presented in a friendly step-by-step fashion, providing useful tips and potential pitfalls. The important steps and results are beautifully illustrated for further ease of use. This collection enables researchers at all stages of their careers to embark on basic biological problems using a variety of technologies and model systems.
This thoroughly updated third edition contains 165 new articles in classical as well as rapidly emerging technologies.
Topics covered include:
* Cell and Tissue Culture: Associated Techniques, Viruses, Antibodies, Immunocytochemistry (Volume 1)
* Organelle and Cellular Structures, Assays (Volume 2)
* Imaging Techniques, Electron Microscopy, Scanning Probe and Scanning Electron Microscopy, Microdissection, Tissue Arrays, Cytogenetics and In Situ Hybridization, Genomics and Transgenic Knockouts and Knock-down Methods (Volume 3)
* Transfer of Macromolecules, Expression Systems, Gene Expression Profiling (Volume 4)
* Indispensable bench companion for every life science laboratory
* Provides the latest information on the plethora of technologies needed to tackle complex biological problems
* Includes numerous illustrations, some in full color, supporting steps and results
"4 Stars - These 4 volumes provide a modern, near encyclopedic review of cell biology protocols."
--Gregory Jay Bix, Thomas Jefferson University in DOODY'S (May 2006)
Praise for the Previous Edition:
"The terms bible and encyclopedic collection are often used of scientific works aspiring to present to the scientific community all the branches of a discipline. Often these terms are misleading! Here they are paradigmatic... could not be more accurate and user-friendly... The book is not only helpful for writing papers, but invaluable for bench work... a masterpiece among scientific publications."
--EUROPEAN JOURNAL OF HISTOCHEMISTRY
"This compendium is a welcome addition to the cell biology laboratory, assembling a wide array of techniques of value to cell biologists...Contributions are by recognized experts in their fields, in some cases the originator of the technique or procedure.
--CHOICE