Additional Information
Book Details
Abstract
Covering pathologic conditions by clinical appearance, Oral Pathology: Clinical Pathologic Correlations, 6th Edition uses an atlas-style format to help you identify, diagnose, and plan treatment for oral disease presentations. Two-page spreads include clinical photos of common conditions on one side while the facing page lists the central features, causes, and significance of each specific disease. Each chapter is organized by clinical appearance, such as white lesions, red-blue lesions, and cysts of the jaws and neck, and includes full-color photomicrographs and clinical photos to help you identify pathologic elements. This edition adds new coverage of oral cancer and new cone beam CT, regular CT, and MRI images. Expert authors Joseph Regezi, James Sciubba, and Richard Jordan provide a quick reference thatÕs ideal for the lab, NBDE review, or chairside use!
- An atlas-style Clinical Overview section makes it easy to find key information, with one page showing clinical photos of common conditions and the facing page listing symptoms, causes, and significance.
- Organization by clinical appearance -- such as including all red-blue lesions in one chapter along with possible causes -- matches what you would expect to see upon a patient's presentation, and provides a practical tool for developing differential diagnoses and planning treatment.
- Hundreds of full-color clinical photographs and radiographs depict specific conditions for easier identification in real clinical scenarios.
- Full-color photomicrographs help you identify pathologic elements and provide correct diagnoses and treatment plans.
- Boxes and tables offer clear, at-a-glance information on the clinical features, diagnosis, and treatment for many conditions.
- Student resources on a companion Evolve website include 30 case studies, a 150-question practice exam, and case-based learning to prepare you for the NBDE and for clinical practice.
- Advanced imaging techniques include images such as CBCTs (cone beam computed tomography), regular CTs, and MRIs, reflecting the transition from a 2-dimensional to a 3-dimensional approach in acquiring data and reconstructing images, and helping you identify and assess disease entities -- especially tumors of the salivary glands, jaws, and soft tissues.
- Expanded sections on etiology, treatment, and diagnosis of oral cancer (HPV) describe how subtypes can play an important role in the development and natural history of some head and neck cancers, most notably those arising in the oropharynx.
- Expanded section on bisphosphonate-related osteonecrosis of the jaws helps you effectively manage patients taking bisphosphonates to prevent bone loss, including information on oral complications, risk factors, and benefits.
Table of Contents
Section Title | Page | Action | Price |
---|---|---|---|
Front cover | cover | ||
Oral Pathology | i | ||
Copyright page | iv | ||
CONTRIBUTORS | v | ||
PREFACE | vii | ||
Who Will Benefit From this Book? | vii | ||
Organization | vii | ||
Distinctive Features of This Book | vii | ||
New to this Edition | vii | ||
Evolve Resources | vii | ||
For the Student | vii | ||
For the instructor | viii | ||
Acknowledgments | viii | ||
Table of Contents | ix | ||
Clinical Overview | O-1 | ||
1 Vesiculobullous Diseases | 1 | ||
Viral Disease | 1 | ||
Herpes Simplex Infection | 1 | ||
Pathogenesis. | 1 | ||
Clinical Features | 3 | ||
Primary Herpetic Gingivostomatitis. | 3 | ||
Secondary, or Recurrent, Herpes Simplex Infection. | 3 | ||
Immunodeficiency. | 4 | ||
Herpetic Whitlow. | 4 | ||
Histopathology. | 5 | ||
Differential Diagnosis. | 5 | ||
Treatment. | 6 | ||
Varicella-Zoster Infection | 6 | ||
Pathogenesis | 6 | ||
Varicella. | 6 | ||
2 Ulcerative Conditions | 22 | ||
Reactive Lesions | 22 | ||
Traumatic Ulcerations | 22 | ||
Etiology. | 22 | ||
Clinical Features. | 23 | ||
Histopathology. | 25 | ||
Diagnosis. | 25 | ||
Treatment. | 26 | ||
Bacterial Infections | 26 | ||
Syphilis | 26 | ||
Etiology and Pathogenesis. | 26 | ||
Clinical Features. | 27 | ||
Histopathology. | 28 | ||
Differential Diagnosis. | 28 | ||
3 White Lesions | 79 | ||
Hereditary Conditions | 79 | ||
Leukoedema | 79 | ||
Etiology and Pathogenesis. | 79 | ||
Clinical Features. | 79 | ||
Histopathology. | 79 | ||
Differential Diagnosis. | 79 | ||
Treatment and Prognosis. | 80 | ||
White Sponge Nevus | 80 | ||
Clinical Features. | 80 | ||
Histopathology. | 80 | ||
Differential Diagnosis. | 80 | ||
4 Red-Blue Lesions | 114 | ||
Intravascular Lesions | 114 | ||
Congenital Vascular Anomalies | 114 | ||
Congenital Hemangiomas and Congenital Vascular Malformations | 114 | ||
Etiology. | 114 | ||
Clinical Features. | 114 | ||
Histopathology. | 115 | ||
Diagnosis. | 115 | ||
Treatment. | 115 | ||
Encephalotrigeminal Angiomatosis (Sturge-Weber Syndrome) | 116 | ||
Hereditary Hemorrhagic Telangiectasia (Rendu-Osler-Weber Syndrome) | 117 | ||
Reactive Lesions | 118 | ||
Varix and Other Acquired Vascular Malformations | 118 | ||
Pyogenic Granuloma | 118 | ||
Etiology. | 118 | ||
Clinical Features. | 118 | ||
Histopathology. | 119 | ||
Differential Diagnosis. | 119 | ||
5 Pigmented Lesions | 134 | ||
Melanocytic Lesions | 134 | ||
Physiologic (Ethnic) Pigmentation | 135 | ||
6 Verrucal-Papillary Lesions | 149 | ||
Reactive/Infectious Lesions | 149 | ||
Squamous Papilloma/Oral Wart | 149 | ||
Etiology. | 149 | ||
Clinical Features. | 150 | ||
Histopathology. | 150 | ||
Dysplastic Oral Warts. | 151 | ||
Differential Diagnosis. | 151 | ||
Treatment and Prognosis. | 151 | ||
Papillary Hyperplasia | 152 | ||
Etiology. | 152 | ||
Clinical Features. | 152 | ||
Histopathology. | 152 | ||
Differential Diagnosis. | 152 | ||
Treatment and Prognosis. | 153 | ||
Condyloma Latum | 153 | ||
Condyloma Acuminatum | 153 | ||
Etiology and Pathogenesis. | 153 | ||
Clinical Features. | 153 | ||
Histopathology. | 153 | ||
7 Connective Tissue Lesions | 162 | ||
Fibrous Lesions | 163 | ||
Reactive Hyperplasias | 163 | ||
Peripheral Fibroma | 163 | ||
Clinical Features. | 163 | ||
Histopathology. | 163 | ||
Differential Diagnosis. | 164 | ||
Treatment. | 164 | ||
Focal Fibrous Hyperplasia | 164 | ||
Etiology. | 164 | ||
Clinical Features. | 164 | ||
Histopathology. | 165 | ||
Differential Diagnosis. | 165 | ||
8 Salivary Gland Diseases | 186 | ||
Reactive Lesions | 187 | ||
Mucus Extravasation Phenomenon | 187 | ||
Etiology and Pathogenesis. | 187 | ||
Clinical Features. | 187 | ||
Histopathology. | 188 | ||
Differential Diagnosis. | 188 | ||
Treatment and Prognosis. | 188 | ||
Mucus Retention Cyst (Obstructive Sialadenitis) | 188 | ||
Etiology and Pathogenesis. | 188 | ||
Clinical Features. | 188 | ||
Histopathology. | 189 | ||
Differential Diagnosis. | 189 | ||
Treatment and Prognosis. | 189 | ||
Maxillary Sinus Retention Cyst/Pseudocyst | 190 | ||
Etiology and Pathogenesis. | 190 | ||
Clinical Features. | 190 | ||
Histopathology. | 190 | ||
Differential Diagnosis. | 190 | ||
Treatment. | 190 | ||
Necrotizing Sialometaplasia | 191 | ||
Etiology and Pathogenesis. | 191 | ||
Clinical Features. | 191 | ||
Histopathology. | 191 | ||
9 Lymphoid Lesions | 226 | ||
Reactive Lesions | 226 | ||
Lymphoid Hyperplasia | 226 | ||
Epithelioid Hemangioma (Angiolymphoid Hyperplasia With Eosinophilia) | 227 | ||
Etiology. | 227 | ||
Clinical Features. | 227 | ||
Histopathology. | 227 | ||
10 Cysts of the Jaws and Neck | 246 | ||
Odontogenic Cysts | 246 | ||
Periapical (Radicular) Cyst | 246 | ||
Etiology and Pathogenesis. | 246 | ||
Clinical Features. | 247 | ||
Histopathology. | 248 | ||
Differential Diagnosis. | 249 | ||
Treatment and Prognosis. | 249 | ||
Lateral Periodontal Cyst | 249 | ||
Etiology and Pathogenesis. | 249 | ||
Clinical Features. | 250 | ||
Histopathology. | 250 | ||
Differential Diagnosis. | 250 | ||
Treatment and Prognosis. | 251 | ||
Gingival Cyst of the Newborn | 251 | ||
Dentigerous Cyst | 251 | ||
Etiology and Pathogenesis. | 251 | ||
Clinical Features. | 251 | ||
Histopathology. | 253 | ||
Differential Diagnosis. | 253 | ||
Treatment. | 253 | ||
Eruption Cyst | 253 | ||
Glandular Odontogenic Cyst | 254 | ||
Clinical Features. | 254 | ||
Radiographic Features. | 254 | ||
Histopathology. | 254 | ||
Treatment and Prognosis. | 254 | ||
Odontogenic Keratocyst/Keratocystic Odontogenic Tumor | 255 | ||
Etiology and Pathogenesis. | 255 | ||
Clinical Features. | 255 | ||
Histopathology. | 256 | ||
Differential Diagnosis. | 258 | ||
Treatment and Prognosis. | 258 | ||
Calcifying Odontogenic Cyst | 259 | ||
Etiology and Pathogenesis. | 259 | ||
Clinical Features. | 259 | ||
Histopathology. | 260 | ||
Differential Diagnosis. | 260 | ||
Treatment and Prognosis. | 260 | ||
Nonodontogenic Cysts | 261 | ||
Globulomaxillary Cyst/Lesion | 261 | ||
Nasolabial Cyst | 261 | ||
Median Mandibular Cyst | 261 | ||
Nasopalatine Canal Cyst | 261 | ||
Etiology and Pathogenesis. | 261 | ||
Clinical Features. | 261 | ||
Histopathology. | 262 | ||
Differential Diagnosis. | 262 | ||
Treatment and Prognosis. | 262 | ||
Pseudocysts | 262 | ||
Aneurysmal Bone Cyst | 262 | ||
Etiology and Pathogenesis. | 263 | ||
Clinical Features. | 263 | ||
Histopathology. | 263 | ||
Differential Diagnosis. | 263 | ||
Treatment and Prognosis. | 263 | ||
Traumatic (Simple) Bone Cyst | 263 | ||
Pathogenesis. | 264 | ||
Clinical Features. | 264 | ||
Histopathology. | 264 | ||
Treatment and Prognosis. | 264 | ||
Static Bone Cyst (Stafne’s Bone Defect) | 264 | ||
Focal Osteoporotic Bone Marrow Defect | 265 | ||
Soft Tissue Cysts of the Neck | 265 | ||
Branchial Cyst/Cervical Lymphoepithelial Cyst | 265 | ||
11 Odontogenic Tumors | 270 | ||
Epithelial Tumors | 270 | ||
Ameloblastoma | 270 | ||
Pathogenesis. | 271 | ||
Clinical Features. | 271 | ||
Biological Subtypes. | 272 | ||
Histopathology. | 275 | ||
Differential Diagnosis. | 277 | ||
Treatment and Prognosis. | 277 | ||
Calcifying Epithelial Odontogenic Tumor (Pindborg Tumor) | 277 | ||
Clinical Features. | 277 | ||
Histopathology. | 278 | ||
Differential Diagnosis. | 278 | ||
Treatment. | 279 | ||
Adenomatoid Odontogenic Tumor | 279 | ||
Clinical Features. | 279 | ||
Histopathology. | 280 | ||
Differential Diagnosis. | 280 | ||
Treatment. | 280 | ||
Squamous Odontogenic Tumor | 280 | ||
Clear Cell Odontogenic Tumor (Carcinoma) | 280 | ||
Mesenchymal Tumors | 282 | ||
Odontogenic Myxoma | 282 | ||
Clinical Features. | 282 | ||
Histopathology. | 283 | ||
Differential Diagnosis. | 283 | ||
Treatment. | 283 | ||
Central Odontogenic Fibroma | 283 | ||
Cementifying Fibroma | 284 | ||
Cementoblastoma | 284 | ||
Clinical Features. | 284 | ||
Histopathology. | 285 | ||
Differential Diagnosis. | 285 | ||
Treatment. | 285 | ||
Periapical Cemento-osseous Dysplasia | 285 | ||
Clinical Features. | 285 | ||
Histopathology. | 287 | ||
Differential Diagnosis. | 287 | ||
Treatment. | 287 | ||
Mixed (Epithelial and Mesenchymal) Tumors | 287 | ||
Ameloblastic Fibroma and Ameloblastic Fibro-odontoma | 287 | ||
Clinical Features. | 287 | ||
Histopathology. | 288 | ||
Differential Diagnosis. | 288 | ||
Treatment. | 289 | ||
Odontoma | 289 | ||
Clinical Features. | 289 | ||
Histopathology. | 290 | ||
Differential Diagnosis. | 290 | ||
Treatment. | 290 | ||
Bibliography | 291 | ||
Odontogenic Tumors | 291 | ||
12 Benign Nonodontogenic Tumors | 293 | ||
Ossifying Fibroma | 294 | ||
Etiology and Pathogenesis | 294 | ||
Clinical Features | 294 | ||
Histopathology | 295 | ||
Differential Diagnosis | 295 | ||
Treatment and Prognosis | 296 | ||
Fibrous Dysplasia | 296 | ||
Etiology and Pathogenesis | 297 | ||
Clinical Features | 297 | ||
Histopathology | 298 | ||
Differential Diagnosis | 298 | ||
Treatment and Prognosis | 299 | ||
Cemento-Osseous Dysplasia | 299 | ||
Osteoblastoma/Osteoid Osteoma | 299 | ||
Clinical Features | 299 | ||
Histopathology | 300 | ||
Differential Diagnosis | 300 | ||
Treatment and Prognosis | 300 | ||
Osteoma | 300 | ||
Clinical Features | 300 | ||
13 Inflammatory Jaw Lesions | 314 | ||
Pulpitis | 314 | ||
Etiology. | 315 | ||
Clinical and Histopathologic Features. | 315 | ||
Focal Reversible Pulpitis. | 315 | ||
Acute Pulpitis. | 315 | ||
Chronic Pulpitis. | 315 | ||
Chronic Hyperplastic Pulpitis. | 316 | ||
Treatment and Prognosis. | 316 | ||
Periapical Abscess | 316 | ||
Etiology. | 316 | ||
Clinical Features. | 316 | ||
Histopathology. | 317 | ||
Treatment and Prognosis. | 318 | ||
Acute Osteomyelitis | 318 | ||
Etiology. | 318 | ||
Clinical Features. | 318 | ||
Histopathology. | 318 | ||
Treatment. | 319 | ||
Chronic Osteomyelitis (Chronic Osteitis) | 319 | ||
Etiology. | 319 | ||
Osteoradionecrosis. | 319 | ||
Clinical Features. | 319 | ||
Histopathology. | 320 | ||
Treatment. | 320 | ||
Bisphosphonate-Related Osteonecrosis | 320 | ||
Bisphosphonate Description. | 320 | ||
Mechanisms of Action. | 321 | ||
Benefits and Risks of Bisphosphonate Therapy. | 321 | ||
Bisphosphonate-Related Osteonecrosis of the Jaws. | 321 | ||
Precipitating Events and Risk Factors for Jaw Disease. | 322 | ||
Treatment of Bisphosphonate-Related Osteonecrosis of the Jaws. | 322 | ||
Dental Management of Patients Undergoing Bisphosphonate Therapy. | 322 | ||
Chronic Osteomyelitis With Proliferative Periostitis (so-called Garré’s Osteomyelitis) | 323 | ||
Etiology. | 323 | ||
Clinical Features. | 323 | ||
Histopathology. | 324 | ||
Treatment. | 324 | ||
Diffuse Sclerosing Osteomyelitis | 324 | ||
Etiology. | 324 | ||
Clinical Features. | 324 | ||
14 Malignancies of the Jaws | 328 | ||
Osteosarcoma | 328 | ||
Clinical Features. | 329 | ||
Histopathology. | 330 | ||
Differential Diagnosis. | 332 | ||
Management. | 332 | ||
Prognosis. | 335 | ||
Juxtacortical Osteosarcoma | 335 | ||
Parosteal Osteosarcoma | 335 | ||
Periosteal Osteosarcoma | 335 | ||
Chondrosarcoma | 336 | ||
Clinical Features. | 336 | ||
Histopathology. | 337 | ||
Differential Diagnosis. | 337 | ||
Treatment and Prognosis. | 337 | ||
Mesenchymal Chondrosarcoma | 338 | ||
Ewing’s Sarcoma and Primitive Neuroectodermal Tumor | 338 | ||
Clinical Features. | 338 | ||
Histopathology. | 339 | ||
Differential Diagnosis. | 339 | ||
Treatment and Prognosis. | 339 | ||
Burkitt’s Lymphoma | 339 | ||
Clinical Features. | 339 | ||
Histopathology. | 340 | ||
Treatment and Prognosis. | 340 | ||
Plasma Cell Neoplasms | 341 | ||
Multiple Myeloma | 341 | ||
Clinical Features. | 341 | ||
Histopathology. | 341 | ||
Differential Diagnosis. | 342 | ||
Treatment and Prognosis. | 342 | ||
Solitary Plasmacytoma of Bone | 343 | ||
Metastatic Carcinoma | 343 | ||
Clinical Features. | 343 | ||
Histopathology. | 344 | ||
Differential Diagnosis. | 345 | ||
Osteonecrosis Related to Metastatic Disease. | 345 | ||
Treatment and Prognosis. | 345 | ||
Bibliography | 346 | ||
Osteosarcoma | 346 | ||
Chondrosarcoma | 346 | ||
Ewing’s Sarcoma | 346 | ||
Plasma Cell Neoplasms | 346 | ||
Metastatic Carcinoma | 346 | ||
Osteonecrosis Related to Metastatic Disease | 346 | ||
15 Metabolic and Genetic Diseases | 347 | ||
Metabolic Conditions | 347 | ||
Paget’s Disease | 347 | ||
Clinical Features. | 347 | ||
Histopathology. | 348 | ||
Treatment. | 349 | ||
Hyperparathyroidism | 349 | ||
Clinical Features. | 350 | ||
Histopathology. | 351 | ||
Treatment. | 351 | ||
Hyperthyroidism | 351 | ||
Hypothyroidism | 351 | ||
Hypophosphatasia | 352 | ||
Infantile Cortical Hyperostosis | 352 | ||
Phantom Bone Disease | 353 | ||
Acromegaly | 353 | ||
Etiology. | 353 | ||
Clinical Features. | 353 | ||
Treatment. | 354 | ||
Genetic Abnormalities | 354 | ||
Cherubism | 354 | ||
Clinical Features. | 355 | ||
Histopathology. | 356 | ||
Treatment and Prognosis. | 356 | ||
Osteopetrosis | 356 | ||
Clinical Features. | 357 | ||
Histopathology. | 358 | ||
Treatment and Prognosis. | 358 | ||
Osteogenesis Imperfecta | 358 | ||
Clinical Features. | 358 | ||
Treatment and Prognosis. | 359 | ||
Cleidocranial Dysplasia | 359 | ||
Etiology and Pathogenesis. | 359 | ||
Clinical Features. | 359 | ||
Treatment. | 360 | ||
Crouzon’s Syndrome (Craniofacial Dysostosis) | 360 | ||
Etiology and Pathogenesis. | 360 | ||
Clinical Features. | 361 | ||
Treatment and Prognosis. | 361 | ||
Treacher Collins Syndrome (Mandibulofacial Dysostosis) | 361 | ||
Etiology and Pathogenesis. | 361 | ||
Clinical Findings. | 362 | ||
16 Abnormalities of Teeth | 373 | ||
Alterations in Size | 373 | ||
Microdontia | 373 | ||
Macrodontia | 373 | ||
Alterations in Shape | 374 | ||
Gemination | 374 | ||
Fusion | 374 | ||
Concrescence | 374 | ||
Dilaceration | 374 | ||
Dens Invaginatus | 375 | ||
Dens Evaginatus | 375 | ||
Taurodontism | 376 | ||
Supernumerary Roots | 377 | ||
Enamel Pearls | 377 | ||
Attrition, Abrasion, Erosion | 377 | ||
Alterations in Number | 378 | ||
Anodontia | 378 | ||
Impaction | 379 | ||
Supernumerary Teeth | 379 | ||
Defects of Enamel | 380 | ||
Environmental Defects of Enamel | 380 | ||
Amelogenesis Imperfecta | 381 | ||
Defects of Dentin | 383 | ||
Dentinogenesis Imperfecta | 383 | ||
Dentin Dysplasia | 384 | ||
Defects of Enamel and Dentin | 385 | ||
Regional Odontodysplasia | 385 | ||
Abnormalities of Dental Pulp | 385 | ||
Pulp Calcification | 385 | ||
Internal Resorption | 386 | ||
External Resorption | 386 | ||
Alterations in Color | 387 | ||
Exogenous Stains | 387 | ||
Endogenous Stains | 387 | ||
Bibliography | 388 | ||
Index | 391 | ||
A | 391 | ||
B | 392 | ||
C | 392 | ||
D | 394 | ||
E | 395 | ||
F | 395 | ||
G | 396 | ||
H | 396 | ||
I | 398 | ||
J | 398 | ||
K | 398 | ||
L | 398 | ||
M | 400 | ||
N | 401 | ||
O | 402 | ||
P | 403 | ||
R | 403 | ||
S | 404 | ||
T | 405 | ||
U | 406 | ||
V | 406 | ||
W | 407 | ||
X | 407 | ||
Z | 407 |