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Oral Pathology - E-Book

Oral Pathology - E-Book

Joseph A. Regezi | James Sciubba | Richard C. K. Jordan

(2012)

Additional Information

Book Details

Abstract

Covering pathologic conditions by clinical appearance, Oral Pathology: Clinical Pathologic Correlations, 6th Edition uses an atlas-style format to help you identify, diagnose, and plan treatment for oral disease presentations. Two-page spreads include clinical photos of common conditions on one side while the facing page lists the central features, causes, and significance of each specific disease. Each chapter is organized by clinical appearance, such as white lesions, red-blue lesions, and cysts of the jaws and neck, and includes full-color photomicrographs and clinical photos to help you identify pathologic elements. This edition adds new coverage of oral cancer and new cone beam CT, regular CT, and MRI images. Expert authors Joseph Regezi, James Sciubba, and Richard Jordan provide a quick reference thatÕs ideal for the lab, NBDE review, or chairside use!

  • An atlas-style Clinical Overview section makes it easy to find key information, with one page showing clinical photos of common conditions and the facing page listing symptoms, causes, and significance.

  • Organization by clinical appearance -- such as including all red-blue lesions in one chapter along with possible causes -- matches what you would expect to see upon a patient's presentation, and provides a practical tool for developing differential diagnoses and planning treatment.
  • Hundreds of full-color clinical photographs and radiographs depict specific conditions for easier identification in real clinical scenarios.
  • Full-color photomicrographs help you identify pathologic elements and provide correct diagnoses and treatment plans.
  • Boxes and tables offer clear, at-a-glance information on the clinical features, diagnosis, and treatment for many conditions.
  • Student resources on a companion Evolve website include 30 case studies, a 150-question practice exam, and case-based learning to prepare you for the NBDE and for clinical practice.
  • Advanced imaging techniques include images such as CBCTs (cone beam computed tomography), regular CTs, and MRIs, reflecting the transition from a 2-dimensional to a 3-dimensional approach in acquiring data and reconstructing images, and helping you identify and assess disease entities -- especially tumors of the salivary glands, jaws, and soft tissues.
  • Expanded sections on etiology, treatment, and diagnosis of oral cancer (HPV) describe how subtypes can play an important role in the development and natural history of some head and neck cancers, most notably those arising in the oropharynx.
  • Expanded section on bisphosphonate-related osteonecrosis of the jaws helps you effectively manage patients taking bisphosphonates to prevent bone loss, including information on oral complications, risk factors, and benefits.

Table of Contents

Section Title Page Action Price
Front cover cover
Oral Pathology i
Copyright page iv
CONTRIBUTORS v
PREFACE vii
Who Will Benefit From this Book? vii
Organization vii
Distinctive Features of This Book vii
New to this Edition vii
Evolve Resources vii
For the Student vii
For the instructor viii
Acknowledgments viii
Table of Contents ix
Clinical Overview O-1
1 Vesiculobullous Diseases 1
Viral Disease 1
Herpes Simplex Infection 1
Pathogenesis. 1
Clinical Features 3
Primary Herpetic Gingivostomatitis. 3
Secondary, or Recurrent, Herpes Simplex Infection. 3
Immunodeficiency. 4
Herpetic Whitlow. 4
Histopathology. 5
Differential Diagnosis. 5
Treatment. 6
Varicella-Zoster Infection 6
Pathogenesis 6
Varicella. 6
2 Ulcerative Conditions 22
Reactive Lesions 22
Traumatic Ulcerations 22
Etiology. 22
Clinical Features. 23
Histopathology. 25
Diagnosis. 25
Treatment. 26
Bacterial Infections 26
Syphilis 26
Etiology and Pathogenesis. 26
Clinical Features. 27
Histopathology. 28
Differential Diagnosis. 28
3 White Lesions 79
Hereditary Conditions 79
Leukoedema 79
Etiology and Pathogenesis. 79
Clinical Features. 79
Histopathology. 79
Differential Diagnosis. 79
Treatment and Prognosis. 80
White Sponge Nevus 80
Clinical Features. 80
Histopathology. 80
Differential Diagnosis. 80
4 Red-Blue Lesions 114
Intravascular Lesions 114
Congenital Vascular Anomalies 114
Congenital Hemangiomas and Congenital Vascular Malformations 114
Etiology. 114
Clinical Features. 114
Histopathology. 115
Diagnosis. 115
Treatment. 115
Encephalotrigeminal Angiomatosis (Sturge-Weber Syndrome) 116
Hereditary Hemorrhagic Telangiectasia (Rendu-Osler-Weber Syndrome) 117
Reactive Lesions 118
Varix and Other Acquired Vascular Malformations 118
Pyogenic Granuloma 118
Etiology. 118
Clinical Features. 118
Histopathology. 119
Differential Diagnosis. 119
5 Pigmented Lesions 134
Melanocytic Lesions 134
Physiologic (Ethnic) Pigmentation 135
6 Verrucal-Papillary Lesions 149
Reactive/Infectious Lesions 149
Squamous Papilloma/Oral Wart 149
Etiology. 149
Clinical Features. 150
Histopathology. 150
Dysplastic Oral Warts. 151
Differential Diagnosis. 151
Treatment and Prognosis. 151
Papillary Hyperplasia 152
Etiology. 152
Clinical Features. 152
Histopathology. 152
Differential Diagnosis. 152
Treatment and Prognosis. 153
Condyloma Latum 153
Condyloma Acuminatum 153
Etiology and Pathogenesis. 153
Clinical Features. 153
Histopathology. 153
7 Connective Tissue Lesions 162
Fibrous Lesions 163
Reactive Hyperplasias 163
Peripheral Fibroma 163
Clinical Features. 163
Histopathology. 163
Differential Diagnosis. 164
Treatment. 164
Focal Fibrous Hyperplasia 164
Etiology. 164
Clinical Features. 164
Histopathology. 165
Differential Diagnosis. 165
8 Salivary Gland Diseases 186
Reactive Lesions 187
Mucus Extravasation Phenomenon 187
Etiology and Pathogenesis. 187
Clinical Features. 187
Histopathology. 188
Differential Diagnosis. 188
Treatment and Prognosis. 188
Mucus Retention Cyst (Obstructive Sialadenitis) 188
Etiology and Pathogenesis. 188
Clinical Features. 188
Histopathology. 189
Differential Diagnosis. 189
Treatment and Prognosis. 189
Maxillary Sinus Retention Cyst/Pseudocyst 190
Etiology and Pathogenesis. 190
Clinical Features. 190
Histopathology. 190
Differential Diagnosis. 190
Treatment. 190
Necrotizing Sialometaplasia 191
Etiology and Pathogenesis. 191
Clinical Features. 191
Histopathology. 191
9 Lymphoid Lesions 226
Reactive Lesions 226
Lymphoid Hyperplasia 226
Epithelioid Hemangioma (Angiolymphoid Hyperplasia With Eosinophilia) 227
Etiology. 227
Clinical Features. 227
Histopathology. 227
10 Cysts of the Jaws and Neck 246
Odontogenic Cysts 246
Periapical (Radicular) Cyst 246
Etiology and Pathogenesis. 246
Clinical Features. 247
Histopathology. 248
Differential Diagnosis. 249
Treatment and Prognosis. 249
Lateral Periodontal Cyst 249
Etiology and Pathogenesis. 249
Clinical Features. 250
Histopathology. 250
Differential Diagnosis. 250
Treatment and Prognosis. 251
Gingival Cyst of the Newborn 251
Dentigerous Cyst 251
Etiology and Pathogenesis. 251
Clinical Features. 251
Histopathology. 253
Differential Diagnosis. 253
Treatment. 253
Eruption Cyst 253
Glandular Odontogenic Cyst 254
Clinical Features. 254
Radiographic Features. 254
Histopathology. 254
Treatment and Prognosis. 254
Odontogenic Keratocyst/Keratocystic Odontogenic Tumor 255
Etiology and Pathogenesis. 255
Clinical Features. 255
Histopathology. 256
Differential Diagnosis. 258
Treatment and Prognosis. 258
Calcifying Odontogenic Cyst 259
Etiology and Pathogenesis. 259
Clinical Features. 259
Histopathology. 260
Differential Diagnosis. 260
Treatment and Prognosis. 260
Nonodontogenic Cysts 261
Globulomaxillary Cyst/Lesion 261
Nasolabial Cyst 261
Median Mandibular Cyst 261
Nasopalatine Canal Cyst 261
Etiology and Pathogenesis. 261
Clinical Features. 261
Histopathology. 262
Differential Diagnosis. 262
Treatment and Prognosis. 262
Pseudocysts 262
Aneurysmal Bone Cyst 262
Etiology and Pathogenesis. 263
Clinical Features. 263
Histopathology. 263
Differential Diagnosis. 263
Treatment and Prognosis. 263
Traumatic (Simple) Bone Cyst 263
Pathogenesis. 264
Clinical Features. 264
Histopathology. 264
Treatment and Prognosis. 264
Static Bone Cyst (Stafne’s Bone Defect) 264
Focal Osteoporotic Bone Marrow Defect 265
Soft Tissue Cysts of the Neck 265
Branchial Cyst/Cervical Lymphoepithelial Cyst 265
11 Odontogenic Tumors 270
Epithelial Tumors 270
Ameloblastoma 270
Pathogenesis. 271
Clinical Features. 271
Biological Subtypes. 272
Histopathology. 275
Differential Diagnosis. 277
Treatment and Prognosis. 277
Calcifying Epithelial Odontogenic Tumor (Pindborg Tumor) 277
Clinical Features. 277
Histopathology. 278
Differential Diagnosis. 278
Treatment. 279
Adenomatoid Odontogenic Tumor 279
Clinical Features. 279
Histopathology. 280
Differential Diagnosis. 280
Treatment. 280
Squamous Odontogenic Tumor 280
Clear Cell Odontogenic Tumor (Carcinoma) 280
Mesenchymal Tumors 282
Odontogenic Myxoma 282
Clinical Features. 282
Histopathology. 283
Differential Diagnosis. 283
Treatment. 283
Central Odontogenic Fibroma 283
Cementifying Fibroma 284
Cementoblastoma 284
Clinical Features. 284
Histopathology. 285
Differential Diagnosis. 285
Treatment. 285
Periapical Cemento-osseous Dysplasia 285
Clinical Features. 285
Histopathology. 287
Differential Diagnosis. 287
Treatment. 287
Mixed (Epithelial and Mesenchymal) Tumors 287
Ameloblastic Fibroma and Ameloblastic Fibro-odontoma 287
Clinical Features. 287
Histopathology. 288
Differential Diagnosis. 288
Treatment. 289
Odontoma 289
Clinical Features. 289
Histopathology. 290
Differential Diagnosis. 290
Treatment. 290
Bibliography 291
Odontogenic Tumors 291
12 Benign Nonodontogenic Tumors 293
Ossifying Fibroma 294
Etiology and Pathogenesis 294
Clinical Features 294
Histopathology 295
Differential Diagnosis 295
Treatment and Prognosis 296
Fibrous Dysplasia 296
Etiology and Pathogenesis 297
Clinical Features 297
Histopathology 298
Differential Diagnosis 298
Treatment and Prognosis 299
Cemento-Osseous Dysplasia 299
Osteoblastoma/Osteoid Osteoma 299
Clinical Features 299
Histopathology 300
Differential Diagnosis 300
Treatment and Prognosis 300
Osteoma 300
Clinical Features 300
13 Inflammatory Jaw Lesions 314
Pulpitis 314
Etiology. 315
Clinical and Histopathologic Features. 315
Focal Reversible Pulpitis. 315
Acute Pulpitis. 315
Chronic Pulpitis. 315
Chronic Hyperplastic Pulpitis. 316
Treatment and Prognosis. 316
Periapical Abscess 316
Etiology. 316
Clinical Features. 316
Histopathology. 317
Treatment and Prognosis. 318
Acute Osteomyelitis 318
Etiology. 318
Clinical Features. 318
Histopathology. 318
Treatment. 319
Chronic Osteomyelitis (Chronic Osteitis) 319
Etiology. 319
Osteoradionecrosis. 319
Clinical Features. 319
Histopathology. 320
Treatment. 320
Bisphosphonate-Related Osteonecrosis 320
Bisphosphonate Description. 320
Mechanisms of Action. 321
Benefits and Risks of Bisphosphonate Therapy. 321
Bisphosphonate-Related Osteonecrosis of the Jaws. 321
Precipitating Events and Risk Factors for Jaw Disease. 322
Treatment of Bisphosphonate-Related Osteonecrosis of the Jaws. 322
Dental Management of Patients Undergoing Bisphosphonate Therapy. 322
Chronic Osteomyelitis With Proliferative Periostitis (so-called Garré’s Osteomyelitis) 323
Etiology. 323
Clinical Features. 323
Histopathology. 324
Treatment. 324
Diffuse Sclerosing Osteomyelitis 324
Etiology. 324
Clinical Features. 324
14 Malignancies of the Jaws 328
Osteosarcoma 328
Clinical Features. 329
Histopathology. 330
Differential Diagnosis. 332
Management. 332
Prognosis. 335
Juxtacortical Osteosarcoma 335
Parosteal Osteosarcoma 335
Periosteal Osteosarcoma 335
Chondrosarcoma 336
Clinical Features. 336
Histopathology. 337
Differential Diagnosis. 337
Treatment and Prognosis. 337
Mesenchymal Chondrosarcoma 338
Ewing’s Sarcoma and Primitive Neuroectodermal Tumor 338
Clinical Features. 338
Histopathology. 339
Differential Diagnosis. 339
Treatment and Prognosis. 339
Burkitt’s Lymphoma 339
Clinical Features. 339
Histopathology. 340
Treatment and Prognosis. 340
Plasma Cell Neoplasms 341
Multiple Myeloma 341
Clinical Features. 341
Histopathology. 341
Differential Diagnosis. 342
Treatment and Prognosis. 342
Solitary Plasmacytoma of Bone 343
Metastatic Carcinoma 343
Clinical Features. 343
Histopathology. 344
Differential Diagnosis. 345
Osteonecrosis Related to Metastatic Disease. 345
Treatment and Prognosis. 345
Bibliography 346
Osteosarcoma 346
Chondrosarcoma 346
Ewing’s Sarcoma 346
Plasma Cell Neoplasms 346
Metastatic Carcinoma 346
Osteonecrosis Related to Metastatic Disease 346
15 Metabolic and Genetic Diseases 347
Metabolic Conditions 347
Paget’s Disease 347
Clinical Features. 347
Histopathology. 348
Treatment. 349
Hyperparathyroidism 349
Clinical Features. 350
Histopathology. 351
Treatment. 351
Hyperthyroidism 351
Hypothyroidism 351
Hypophosphatasia 352
Infantile Cortical Hyperostosis 352
Phantom Bone Disease 353
Acromegaly 353
Etiology. 353
Clinical Features. 353
Treatment. 354
Genetic Abnormalities 354
Cherubism 354
Clinical Features. 355
Histopathology. 356
Treatment and Prognosis. 356
Osteopetrosis 356
Clinical Features. 357
Histopathology. 358
Treatment and Prognosis. 358
Osteogenesis Imperfecta 358
Clinical Features. 358
Treatment and Prognosis. 359
Cleidocranial Dysplasia 359
Etiology and Pathogenesis. 359
Clinical Features. 359
Treatment. 360
Crouzon’s Syndrome (Craniofacial Dysostosis) 360
Etiology and Pathogenesis. 360
Clinical Features. 361
Treatment and Prognosis. 361
Treacher Collins Syndrome (Mandibulofacial Dysostosis) 361
Etiology and Pathogenesis. 361
Clinical Findings. 362
16 Abnormalities of Teeth 373
Alterations in Size 373
Microdontia 373
Macrodontia 373
Alterations in Shape 374
Gemination 374
Fusion 374
Concrescence 374
Dilaceration 374
Dens Invaginatus 375
Dens Evaginatus 375
Taurodontism 376
Supernumerary Roots 377
Enamel Pearls 377
Attrition, Abrasion, Erosion 377
Alterations in Number 378
Anodontia 378
Impaction 379
Supernumerary Teeth 379
Defects of Enamel 380
Environmental Defects of Enamel 380
Amelogenesis Imperfecta 381
Defects of Dentin 383
Dentinogenesis Imperfecta 383
Dentin Dysplasia 384
Defects of Enamel and Dentin 385
Regional Odontodysplasia 385
Abnormalities of Dental Pulp 385
Pulp Calcification 385
Internal Resorption 386
External Resorption 386
Alterations in Color 387
Exogenous Stains 387
Endogenous Stains 387
Bibliography 388
Index 391
A 391
B 392
C 392
D 394
E 395
F 395
G 396
H 396
I 398
J 398
K 398
L 398
M 400
N 401
O 402
P 403
R 403
S 404
T 405
U 406
V 406
W 407
X 407
Z 407