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Clinical Gastroenterology

Clinical Gastroenterology

Nicholas J Talley

(2011)

Additional Information

Book Details

Abstract

A new edition of this respected Australian gastroenterology textbook

Completely updated, this comprehensive medical resource offers a practical, problem-based approach to the subject of clinical gastroenterology.

Containing specialist content from Australian and international contributors, Clinical Gastroenterology, 3rd Edition focuses on both common and uncommon gastroenterological problems as they present in clinical practice.

Building on the previous two editions, Clinical Gastroenterology features decision trees to assist clinicians in assessing patients and the treating digestive disorders.

This latest edition also includes clear medical illustrations suitable for patient education, along with summary tables highlighting key points to guide General Practitioners, gastroenterology specialist trainees and medical students

New to this edition
• each chapter commences with a case study and contains key point summaries at the end
• new chapters on inflammatory bowel disease; obesity and anti-obesity surgery; principles of anaesthesia for endoscopy and preparing patients for endoscopy; complications of endoscopy; liver transplant and end-stage liver disease
• expanded sections on pancreatic masses and cysts, and radiological evaluation including the place of cross-sectional imaging
• gastroenterological case studies and key point summaries in each chapter
• new chapters on gastroenterological and hepatological medical conditions, including inflammatory bowel disease, obesity and anti-obesity surgery, principles of anaesthesia for endoscopy and preparing patients for endoscopy, complications of endoscopy, liver transplant and end-stage liver disease
• an expanded section on pancreatic cysts and masses
• an expanded section on radiological evaluation including the place of cross-sectional imaging

Table of Contents

Section Title Page Action Price
Front Cover\r Cover
Clinical gastroenterology iii
Copyright\r iv
Dedication v
Foreword\r vii
Contents ix
Preface xi
Contributors xiii
Chapter 1 - Heartburn, regurgitation and non-cardiac chest pain 1
Case\r 1
History 1
Examination 3
Pathophysiology of GORD 3
Investigation of Heartburn and Acid Regurgitation 4
Treatment 7
Non-cardiac Chest Pain 12
Key Points 14
Chapter 2 - Difficulty swallowing and pain on swallowing 15
Case\r 15
Pain on Swallowing (Odynophagia) 15
Dysphagia 16
Key Points 26
Chapter 3 - Hiccups, sore mouth and bad breath 27
Case\r 27
Hiccups 27
Sore Mouth 31
Bad Breath 33
Key Points 35
Chapter 4 - Acute abdominal pain 37
Case\r 37
Introduction 37
Mechanisms Of Abdominal Pain 38
Pathological Causes 38
Clinical Evaluation 40
Generalised Abdominal Pain 40
Acute Abdominal Colic 46
Acute Epigastric Pain 50
Acute Pancreatitis And Its Complications 51
Right Upper Quadrant Pain 55
Right Iliac Fossa Pain 61
Left Iliac Fossa Pain 63
Key Points 64
Chapter 5 - When to test for Helicobacter pylori and what to do with a positive test 66
Case\r 66
Introduction 66
Pathogenesis 66
Management Guidelines 67
Summary 72
Key Points 72
Chapter 6 - Indigestion (chronic epigastric pain or meal-related discomfort) 73
Case\r 73
Indigestion and Dyspepsia 73
Mechanisms Underlying Epigastric Pain 73
Clinical Assessment 74
Chronic Peptic Ulcer 75
Management of Dyspepsia 76
Diseases Associated With Epigastric Pain or Discomfort 78
Key Points 86
Chapter 7 - Chronic lower abdominal pain or discomfort 88
Case\r 88
Introduction 88
History 88
Differential Diagnosis 90
Clinical Evaluation 94
Irritable Bowel Syndrome (IBS) 95
Key Points 98
Chapter 8 - Wind and gas 100
Case\r 100
Introduction 100
History 100
Physical Examination 100
Investigations 100
Laboratory Tests 102
Physiology of Gas 103
Composition 103
Symptoms Associated with Intestinal Gas 103
Key Points 105
Chapter 9 - Nausea and vomiting 106
Case\r 106
Definition 106
Physiology of Vomiting 106
History 107
Physical Examination 108
Investigation 108
Consequences of Nausea and Vomiting 110
Important Diseases that may cause Nausea and Vomiting 110
Principles of Treatment 112
Specific Clinical Scenarios 113
Key Points 113
Chapter 10 - Vomiting blood, black stools, blood per rectum, occult bleeding 115
Case\r 115
Introduction 115
Vomiting Blood 116
Passing Melaena Alone 122
Bright Red Blood Per Rectum 123
Iron Deficiency Anaemia 126
Positive Faecal Occult Blood Test 127
Key Points 128
Chapter 11 - Constipation 130
Case\r 130
Introduction 130
Clinical Approach to Patients with Constipation 131
Investigations 132
Approach to Management 135
Surgical Treatment 136
Clinical Approach to Specific Types of Constipation 137
Key Points 139
Chapter 12 - Perianal pain 141
Case\r 141
Introduction 142
History 142
Examination 142
Fissure-in-Ano 143
Anal Sepsis 145
Haemorrhoids 150
Pruritus Ani 154
Chronic Perianal Pain Syndromes 155
Key Points 156
Chapter 13 - Acute diarrhoea 158
Case\r 158
Introduction 158
Clinical Approach to Acute Diarrhoea 159
Therapy 162
Conditions Causing Food-borne Illnesses 162
Travellers’ Diarrhoea 164
Conditions Causing Acute Watery Diarrhoea 165
Conditions Causing Acute Blood Diarrhoea 167
Antibiotic-associated Diarrhoea and C. difficle Colitis 171
Cryptosporidiosis 172
Diarrhoea Associated with AIDS 172
Key Points 173
Chapter 14 - Chronic diarrhoea and fatty stools 174
Case\r 174
Introduction 174
History 174
Physical Examination 175
Assessment 176
Approach to Chronic Diarrhoea 176
Malabsorption 176
Clinical Approach to the Patient with Malabsorption 180
Disorders that may Cause Chronic Diarrhoea or Malabsorption 183
Inflammatory Bowel Disease 188
Collagenous and Microscopic Colitis 189
Key Points 189
Chapter 15 - Inflammatory bowel disease 190
Case\r 190
Introduction 190
Ulcerative Colitis 191
Crohn's Disease 198
Key Points 204
Chapter 16 - Faecal incontinence (leakage of stool) 206
Case\r 206
Introduction 206
Definitions 206
History 207
Examination 207
Physiological Anorectal Assessment 208
Conditions Causing Incontinence with a Normal Sphincter 211
Conditions Causing Incontinence with an Abnormal Sphincter 213
Key Points 218
Chapter 17 - Loss of appetite and loss of weight 220
Case\r 220
Introduction 220
Pathophysiology of Anorexia and Weight Loss 221
Clinical Approach to Anorexia and Weight Loss 222
Management of Patients with Weight Loss 226
Nutritional Support 228
Diseases Associated with Weight Loss 231
Key Points 237
Chapter 18 - Food allergies and intolerance 238
Case\r 238
Introduction 238
A Clinical Approach 238
Identification of Food Allergens 239
Food Intolerance 242
Summary 243
Key Points 244
Chapter 19 - Palpable asymptomatic abdominal masses 246
Case\r 246
Introduction 246
Examination of the Abdomen 247
Documenting the Finding of an Abdominal Mass 247
Masses within the Abdominal Wall 247
Retroperitoneal Masses 249
Intraabdominal Masses 249
Office Tests 255
Imaging 255
Other Investigations 261
Key Points 262
Chapter 20 - Abdominal distension 263
Case\r 263
Preliminary Examination of the Abdomen 263
History and Further Examination 264
Clinical Features 264
Investigations 267
Diagnosis of Ascites 268
Management of Ascites 269
Key Points 270
Chapter 21 - Lumps in the groin and hernia 271
Case\r 271
Introduction 271
History 271
Physical Examination 272
Management of Groin Lumps 276
Key Points 278
Chapter 22 - Rectal/perianal mass and colorectal cancer 279
Case\r 279
Rectal or Perianal Mass 279
Tumours of the Colon and Rectum 281
Anal Canal Cancer 290
Key Points 291
Chapter 23 - Jaundice and pruritus 293
Case\r 293
Introduction 293
Clinical Syndromes 296
Diagnostic Tests 298
Management of Suspected Obstructive Jaundice 301
Pruritus 303
The Postsurgical and Critically Ill Jaundiced Patient 303
The Immunocompromised Patient who is Jaundiced 304
Key Points 305
Chapter 24 - Abnormal liver function test results 307
Case\r 307
An Approach to the Patient with Liver Disease 307
Liver Function Test Interpretation 308
Tests of Liver Injury 309
The Well Patient with Abnormal Liver Function Profile 312
The Sick Patient with Jaundice: Acute Liver Disease 315
Acute Liver Failure 316
Patients Presenting with Cirrhosis and its Complications 318
The Well Patient with Cirrhosis 319
Complications of Portal Hypertension in the Patient with Chronic Liver Disease 319
Ascites in the Cirrhotic Patient with or without Renal Impairment 322
Ascites, Fever and Pain: Spontaneous Bacterial Peritonitis 323
Hepatic Encephalopathy in the Cirrhotic Patient 324
Liver Disease in Pregnancy 325
Specific Hepatic Diseases 327
Key Points 344
Chapter 25 - Management of end-stage liver disease and liver transplantation 346
Case\r 346
Introduction 346
End-stage Liver Disease 346
Orthotopic Liver Transplantation 353
Key Points 354
Chapter 26 - Abdominal incidentalomas 356
Case\r 356
Diagnosis and Management 356
Biliary Incidentalomas 358
Pancreatic Incidentalomas 361
Hepatic Incidentalomas 364
Retroperitoneal Masses 371
Mesenteric Masses 373
Key Points 374
Chapter 27 - Obesity and anti-obesity medical and surgical management 375
Case, Part 1\r 375
Introduction 375
Medical Management 375
Case, Part 2 376
Surgical Management 376
Pros and Cons of Weight-loss Surgery 378
Case, Conclusion 378
Conclusions 378
Key Points 379
Chapter 28 - Patient preparation and principles of sedation in gastrointestinal endoscopy 381
Case\r 381
Introduction 381
Preparing Patients for Endoscopy 382
Principles of Anaesthesia for Endoscopy 385
Key Points 389
Index 391