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Current Therapy in Equine Medicine - E-Book

Current Therapy in Equine Medicine - E-Book

N. Edward Robinson | Kim A. Sprayberry

(2008)

Additional Information

Book Details

Abstract

Stay up-to-date on the latest advances and current issues in equine medicine with this handy reference for the busy equine practitioner, large animal veterinarian, or student. This edition of Current Therapy in Equine Medicine brings you thorough coverage and expert advice on selected topics in areas that have seen significant advances in the last 5 years. Content emphasizes the practical aspects of diagnosis and treatment and provides details for therapeutic regimens. Arranged primarily by body system, the text also features sections on infectious diseases, foal diseases, nutrition, and toxicology. With this cutting-edge information all in one reliable source, you’ll increase your awareness of key therapies in less time.

  • Focuses on the latest therapy for equine diseases, emphasizing detailed discussions and the most reliable and current information.
  • Organized approach to important problems brings you up-to-date, practical information organized by organ system.
  • Concise, easy-to-read format saves you time; most articles provide essential information in 2 to 5 pages.
  • Renowned group of contributors share their expertise on the timely topics you need to know about.
  • Photos enhance information.
  • Line drawings illustrate important concepts.
  • NEW! Emerging topics include issues such as disinfection in equine hospitals; complimentary modalities to traditional medicine; chemotherapy for oncological diseases; and protecting yourself with medical records.
  • Each section has NEW topics including medical management of critically ill foals in the field; oral cavity masses; radiology of sinuses and teeth; biochemical tests for myocardial injury; protozoal myeloencephalitis update; management of bladder uroliths; skin grafting; managing the high-risk pregnancy; shock wave therapy; and more!

Table of Contents

Section Title Page Action Price
Front Cover Cover
EQUINE MEDICINE iii
Copyright Page iv
Contributors v
Dedication xvii
Preface xviii
Contents xxi
SECTION I Clinical Pharmacology 1
CHAPTER 1 Adverse Drug Reactions 1
DEFINITIONS 1
CLASSIFICATION OF ADVERSE DRUG REACTIONS 1
DIAGNOSIS OF ADVERSE DRUG REACTIONS 2
DIAGNOSIS OF DRUG TOXICITY BY SYSTEM 2
PREVENTION OF ADVERSE DRUG REACTIONS 5
REPORTING ADVERSE DRUG REACTIONS 5
Suggested Reading 6
CHAPTER 2 Nonsteroidal Anti-inflammatory Drugs 7
Suggested Reading 9
CHAPTER 3 Update on Common Antimicrobials 10
β-LACTAM ANTIMICROBIALS 10
MACROLIDE ANTIMICROBIALS 11
UPDATE ON DOXYCYCLINE 12
ENROFLOXACIN 12
FLORFENICOL IN HORSES 13
ANTIMICROBIALS IN THE PREGNANT MARE 13
Suggested Reading 13
CHAPTER 4 Systemic Chemotherapy for oncologic Diseases 15
THEORETICAL CONCEPTS 15
PROTOCOLS 15
MONITORING 17
TOXICITY 17
SAFETY CONCERNS IN HANDLING CYTOTOXIC DRUGS 17
Suggested Reading 18
CHAPTER 5 Fluphenazine Toxicosis 19
USE OF FLUPHENAZINE 19
CLINICAL SIGNS 20
DIAGNOSIS 20
TREATMENT 20
PROGNOSIS 20
CHAPTER 6 Field Anesthesia 21
BASIC PRINCIPLES 23
KETAMINE AND TILETAMINE 24
USE OF ANESTHETIC ADJUNCTS TO RESOLVE COMMON PROBLEMS OF FIELD ANESTHESIA 24
Suggested Reading 26
CHAPTER 7 Anesthesia at High Altitude 27
PHYSIOLOGIC ADAPTATIONS 27
ANESTHETIC MANAGEMENT 27
ANESTHETIC EQUIPMENT 28
Suggested Reading 28
CHAPTER 8 Anesthesia and Sedation of Miniature Horses 29
PREOPERATIVE CONSIDERATIONS 29
INDUCTION OF ANESTHESIA 30
MAINTENANCE OF ANESTHESIA AND MONITORING 31
BLOOD PRESSURE MONITORING 31
RECOVERY AND POSTOPERATIVE ­ANALGESIA 32
SUMMARY 32
Suggested Reading 32
SECTION II Medico-Legal 33
CHAPTER 9 Reading and Interpreting scientific literature 33
CONFOUNDING AND THE ABSENCE OF GROUP COMPARABILITY 33
THE FALLACY OF STATISTICAL SIGNIFICANCE IN MEDICAL RESEARCH 34
CENSORING AND FOLLOW-UP VALIDITY 35
CONFLICTS OF INTEREST AND ETHICS OF AUTHORSHIP 35
CONCLUDING REMARKS 36
Suggested Reading 36
CHAPTER 10 Equine Insurance 37
TYPES OF INSURANCE 37
ROLE OF THE VETERINARIAN ON BEHALF OF THE INSURED HORSE 38
Suggested Reading 38
CHAPTER 11 Protecting yourself with Medical Records 39
THE CLIENT’S BILL IS NOT THE PATIENT’S MEDICAL RECORD 39
DOCUMENTATION GUIDELINES 40
OWNERSHIP AND CONTROL OF MEDICAL RECORDS 41
Suggested Reading 42
CHAPTER 12 The Unwanted Horse: An overview of the Issue 43
DEMOGRAPHICS OF THE UNWANTED HORSE 43
INFRASTRUCTURE COSTS FOR UNWANTED HORSES 44
CURRENT OPTIONS 44
PENDING LEGISLATION AND INDUSTRY INITIATIVES 45
Suggested Reading 46
CHAPTER 13 Field Necropsy of the Horse 47
PREPARING TO PERFORM THE NECROPSY 47
DOCUMENTING THE NECROPSY FINDINGS 48
COLLECTING SAMPLES DURING THE NECROPSY 48
STEPWISE NECROPSY PROCEDURE 48
SUMMARY 52
Suggested Reading 52
SECTION III Nutrition 53
CHAPTER 14 Nutritional Management of the Starved Horse 53
METABOLIC RESPONSE TO STARVATION 53
EVALUATION OF NUTRITIONAL STATUS 53
NUTRITIONAL SUPPORT 54
MONITORING 57
PROGNOSIS 58
Suggested Reading 58
CHAPTER 15 Dietary Management of the Obese Horse 59
DEFINITION OF OBESITY 59
ASSESSMENT OF ADIPOSITY IN THE HORSE 59
DEFINITION, PREVALENCE, AND UNDERLYING CAUSES OF OBESITY 62
DISEASE ASSOCIATION 62
WEIGHT MANAGEMENT PROGRAMS 63
Suggested Reading 65
CHAPTER 16 Updates to the Nutrient Requirements of the Horse: NRC 2007 Guidelines 66
NONBREEDING ADULT HORSES 66
REGULARLY EXERCISED ADULT HORSES 67
STALLIONS 69
BROODMARES 69
GROWING HORSES 70
Suggested Reading 72
CHAPTER 17 Antioxidants and Horse Health 73
ROLE OF OXIDANTS AND ANTIOXIDANTS FOR HEALTH 73
BIOMARKERS OF OXIDATIVE STRESS 75
CONDITIONS OF OXIDATIVE STRESS IN EQUINE MEDICINE 76
ANTIOXIDANTS AS FEED ADDITIVES 77
Suggested Reading 78
CHAPTER 18 Nutritional Factors in Developmental Orthopedic Disease 79
POTENTIAL NUTRITIONAL CAUSES OF ­DEVELOPMENTAL ORTHOPEDIC DISEASE 79
OTHER FACTORS TO BE CONSIDERED IN DOD 81
PREVENTION 82
Suggested Reading 82
CHAPTER 19 The Pros and Cons of Probiotics 83
SURVIVAL OF PROBIOTICS IN THE GASTROINTESTINAL TRACT 83
MODE OF ACTION OF PROBIOTICS 83
EFFECT OF PROBIOTICS 84
THE RISK OF PROBIOTIC ADMINISTRATION AND REGULATION IN EUROPE 85
CONCLUSION 85
PRACTICAL RECOMMENDATIONS FOR VETERINARIANS 86
Suggested Reading 86
CHAPTER 20 Herbs and Nutraceuticals 87
HERBAL ACTIONS AND USES 87
HERB-DRUG INTERACTIONS 87
SPECIFIC HERBS 90
SPICES 92
OTHER NUTRACEUTICALS 92
Suggested Reading 93
CHAPTER 21 Use of Nutraceuticals for Equine Joint Disease 94
WHAT ARE NUTRACEUTICALS? 94
LICENSING AND PROOF OF EFFICACY 94
Suggested Reading 96
CHAPTER 22 nutrition for the Critically Ill Horse 97
NUTRIENT METABOLISM IN HEALTH AND DISEASE 97
IMPORTANCE OF ENTERAL NUTRITION 97
PARENTERAL NUTRITION 99
Suggested Reading 102
SECTION IV Behavior 103
CHAPTER 23 Headshaking Syndrome 103
PRESENTING SIGNS 103
EXAMINATION AND DIAGNOSIS 104
ETIOLOGY 105
TREATMENT 106
PROGNOSIS 107
CONCLUSION 107
Suggested Reading 107
CHAPTER 24 Management of Stereotypic Behavior (Stable Vices) 108
GENERAL FACTORS AFFECTING THE RISK OF STEREOTYPIC BEHAVIOR 108
WEAVING AND STALL WALKING 108
CRIBBING AND WINDSUCKING 110
WOOD CHEWING 111
SUMMARY 111
Suggested Reading 111
CHAPTER 25 Aggression in Horses 112
HUMAN-DIRECTED AGGRESSION 112
SEXUAL AGGRESSION 114
MATERNAL AGGRESSION 115
OTHER AGGRESSION 115
Suggested Reading 115
CHAPTER 26 Foal Rejection 116
RISK FACTORS FOR FOAL REJECTION 116
TREATMENT OF FOAL REJECTION 116
CASE HISTORIES 118
Suggested Reading 118
CHAPTER 27 Transportation of Horses 119
TRANSPORT-RELATED STRESS 119
MAXIMUM DURATION OF TRANSPORT 119
DEHYDRATION AND WEIGHT LOSS 119
FATIGUE 120
PERSONALITY 121
REST STOPS 121
SECTION V Infectious Disease 124
CHAPTER 28 Strangles: Immunology and Management 124
IMMUNOLOGY OF STRANGLES 124
MANAGEMENT 126
DETECTION OF S. EQUI IN CLINICAL SPECIMENS 127
OUTBREAK MANAGEMENT 127
TREATMENT 128
Suggested Reading 128
CHAPTER 29 Epidemiology of Rhodococcus equi Pneumonia in Foals 129
PREVALENCE 129
AGENT, ENVIRONMENT, AND HOST 129
RISK FACTORS 130
Suggested Reading 130
CHAPTER 30 Control of Salmonella and Nosocomial Infections 132
SALMONELLA INFECTIONS 132
NOSOCOMIAL INFECTION BASICS 133
BIOSECURITY PLAN 134
COMMUNICATIONS AND CLIENT EDUCATION 135
SUMMARY 135
Suggested Reading 138
CHAPTER 31 Pneumonia Caused by Rhodococcus equi Infection in Foals 139
PATHOGENESIS 139
CLINICAL MANIFESTATIONS 139
DIAGNOSIS 140
TREATMENT 140
PREVENTION 141
Suggested Reading 142
CHAPTER 32 Lyme Disease 143
CLINICAL SIGNS 143
DIAGNOSIS 143
TREATMENT 144
Suggested Reading 144
CHAPTER 33 Leptospirosis 145
CLINICAL SYNDROMES 145
DIAGNOSIS 146
TREATMENT 146
PREVENTION 146
Suggested Reading 147
CHAPTER 34 Systemic Illness Caused by Corynebacterium pseudotuberculosis 148
DIAGNOSIS 148
TREATMENT 151
PROGNOSIS 151
Suggested Reading 152
CHAPTER 35 Equine Viral Arteritis 153
ETIOLOGY 153
EPIDEMIOLOGY 153
IMMUNITY 154
INDUSTRY TRENDS 154
CLINICAL SIGNS 154
ECONOMIC SIGNIFICANCE 155
DIAGNOSIS 155
TREATMENT 156
PREVENTION AND CONTROL 156
Suggested Reading 157
CHAPTER 36 Clostridial Diseases 158
CLOSTRIDIUM DIFFICILE COLITIS 158
CLOSTRIDIUM PERFRINGENS COLITIS 160
CLOSTRIDIAL MYONECROSIS 161
BOTULISM 163
GRASS SICKNESS 164
TETANUS 164
TYZZER’S DISEASE 166
DUODENITIS-PROXIMAL JEJUNITIS 166
ACUTE PASTURE MYODYSTROPHY 166
Suggested Reading 166
CHAPTER 37 Methicillin-Resistant Staphylococci 167
METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS 167
OTHER COAGULASE POSITIVE METHICILLIN-RESISTANT STAPHYLOCOCCI 170
METHICILLIN-RESISTANT COAGULASE NEGATIVE STAPHYLOCOCCI 171
Suggested Reading 171
CHAPTER 38 Lawsonia intracellularis Enteropathy in Foals 172
EPIDEMIOLOGY 172
PATHOGENESIS 172
CLINICAL SIGNS 173
LABORATORY FINDINGS 173
DIAGNOSIS 173
DIFFERENTIAL DIAGNOSIS 174
PATHOLOGIC CHANGES 175
TREATMENT 175
PROGNOSIS 175
PREVENTION 175
Suggested Reading 176
CHAPTER 39 Equine Herpesvirus Myeloencephalopathy 177
PATHOGENESIS 177
CLINICAL SIGNS 178
FACTORS THAT DETERMINE OCCURRENCE 178
EPIDEMIOLOGY 178
DIAGNOSIS 178
TREATMENT 179
THE RECUMBENT HORSE 180
OUTBREAK MANAGEMENT 180
PREVENTION 180
Suggested Reading 181
SECTION VI The Cardiovascular System 182
CHAPTER 40 Cardiovascular Pharmacology 182
ANTIARRHYTHMICS 182
DIGITALIS GLYCOSIDES 189
ADRENERGIC (SYMPATHOMIMETIC) AGENTS 189
ANTICHOLINERGIC (VAGOLYTIC) AGENTS 190
ANGIOTENSIN-CONVERTING ENZYME (ACE) INHIBITORS 190
VASODILATORS AND INODILATORS 190
DIURETICS 190
Suggested Reading 191
CHAPTER 41 Management of Atrial Fibrillation 192
MECHANISMS AND PATHOPHYSIOLOGY 192
CLINICAL PRESENTATION 192
TREATMENT 193
AFTERCARE 196
Suggested Reading 197
CHAPTER 42 The Effects of Training on Echocardiographic Measurements 198
STRUCTURAL MYOCARDIAL ALTERATIONS RESULTING FROM EXERCISE 198
EFFECT OF TRAINING ON VALVULAR REGURGITATION 198
ECHOCARDIOGRAPHIC EVALUATION IN EQUINE ATHLETES 199
VARIABILITY OF ECHOCARDIOGRAPHIC MEASUREMENTS OF CARDIAC DIMENSIONS 200
VALVULAR REGURGITATION 201
CARDIAC DIMENSIONS AND RELATIONSHIP TO PERFORMANCE 202
CONCLUSIONS 203
Suggested Reading 203
CHAPTER 43 CLINICAL SIGNS 204
CLINICAL SIGNS 204
DIAGNOSIS 205
TREATMENT 205
PROGNOSIS 206
Suggested Reading 206
CHAPTER 44 Pericarditis 207
CLINICAL SIGNS 207
DIAGNOSIS 208
TREATMENT 209
PROGNOSIS 211
Suggested Reading 211
CHAPTER 45 Infective Endocarditis 212
ETIOLOGY 212
CLINICAL SIGNS 212
DIAGNOSIS 213
TREATMENT 214
PROGNOSIS 215
CONCLUSION 215
Suggested Reading 215
CHAPTER 46 Pulmonary Hypertension 216
PATHOPHYSIOLOGY 216
PULMONARY HYPERTENSION AND ACQUIRED HEART DISEASE 216
PULMONARY HYPERTENSION AND CONGENITAL CARDIAC DISEASE 217
PULMONARY HYPERTENSION AND LUNG DISEASE 217
PERSISTENT PULMONARY HYPERTENSION OF THE NEWBORN 217
EMBOLIC PULMONARY HYPERTENSION 218
DIAGNOSIS 218
TREATMENT 220
Suggested Reading 220
CHAPTER 47 Biochemical Tests for Cardiac Injury 221
REFERENCE RANGES IN HEALTHY HORSES 221
CLINICAL APPLICATIONS 221
Suggested Reading 222
CHAPTER 48 Blood-Donor Horses and Whole-Blood Transfusion in Private Practice 224
TRANSFUSION TRIGGERS 224
EQUINE BLOOD TYPES 224
WHOLE BLOOD DONORS 224
WHOLE-BLOOD COLLECTION 225
WHOLE-BLOOD TRANSFUSION 225
Suggested Reading 226
CHAPTER 49 Coagulopathies 227
INHERITED COAGULOPATHIES 227
ACQUIRED COAGULOPATHIES 227
Suggested Reading 231
SECTION VII The Respiratory System 232
CHAPTER 50 Dental Radiography in Relation to Sinus Disease 232
DENTAL DISEASE 232
EXAMINATION 233
RADIOGRAPHIC EXAMINATION 233
RADIOGRAPHIC FINDINGS 235
Suggested Reading 238
CHAPTER 51 Sinoscopy and Sinus Surgery in the Standing Horse 239
SINOSCOPY 239
SINUS SURGERY 240
Suggested Reading 242
CHAPTER 52 Ultrasonographic Examination of the Upper Airway 243
EQUIPMENT AND PREPARATION 243
ULTRASOUND TECHNIQUE 244
CHARACTERIZATION OF ACOUSTIC WINDOWS 244
CLINICAL APPLICATIONS 245
Suggested Reading 249
CHAPTER 53 Disorders of the Guttural Pouch 250
GUTTURAL POUCH MYCOSIS 250
GUTTURAL POUCH EMPYEMA 252
GUTTURAL POUCH TYMPANY 253
TEMPOROHYOID OSTEOARTHROPATHY 254
Suggested Reading 254
CHAPTER 54 Efficacy of Surgery for Laryngeal Hemiplegia 255
LARYNGEAL REINNERVATION 255
ARYTENOIDECTOMY 256
Suggested Reading 257
CHAPTER 55 Surgical Advancement of the Larynx for Treatment of Dorsal Displacement of the Soft Palate 258
CASE SELECTION 258
SURGICAL TECHNIQUE 258
RESULTS 259
Suggested Reading 260
CHAPTER 56 Disorders of the Trachea 261
LATERAL TRACHEAL FLATTENING 261
DORSOVENTRAL TRACHEAL COLLAPSE 261
EXTERNAL TRACHEAL TRAUMA 262
TRACHEOBRONCHIAL FOREIGN BODIES 263
EXTRAMURAL TRACHEAL COMPRESSION 263
TRACHEAL TUMORS AND GROWTHS 263
Suggested Reading 263
CHAPTER 57 Cough 264
MECHANISM OF COUGH 264
EXAMINING THE COUGHING HORSE 265
PHYSICAL EXAMINATION 265
ULTRASOUND EVALUATION 267
RADIOGRAPHIC EXAMINATION 267
ENDOSCOPIC EXAMINATION 267
OTHER DIAGNOSTIC TESTS 267
TREATMENT 268
Suggested Reading 268
CHAPTER 58 Viral Respiratory Diseases 269
COMMON VIRUSES CAUSING UPPER RESPIRATORY TRACT DISEASE 269
OTHER VIRUSES ASSOCIATED WITH URTD 271
EXOTIC VIRUSES CAUSING RESPIRATORY DISEASE 271
DIAGNOSIS Of VIRAl RESPIRATORY DISEASE 272
MANAGEMENT, CONTROl, AND TREATMENT Of VIRAl RESPIRATORY DISEASES 273
Suggested Reading 273
CHAPTER 59 Antimicrobial Therapy of the Respiratory System 274
INDICATIONS FOR ANTIMICROBIAL THERAPY 274
CONSIDERATIONS REGARDING PULMONARY ANTIMICROBIAL THERAPY 274
ANTIVIRAL THERAPY 276
ANTIFUNGAL THERAPY 276
AEROSOL ADMINISTRATION 277
MONITORING TREATMENT 278
Suggested Reading 278
CHAPTER 60 Multimodal Management of the Horse with Airway Disease 279
RISK FACTORS FOR AIRWAY DISEASE 279
ASSESSMENT OF THE ENVIRONMENT 280
VARIATIONS IN ENVIRONMENTAL EXPOSURE 280
MANAGEMENT OF THE HORSE WITH AIRWAY DISEASE 281
Suggested Reading 283
CHAPTER 61 Management of Inflammatory Airway Disease in Pleasure Horses 284
MANAGEMENT 284
PHARMACOLOGIC MANAGEMENT 285
PROGNOSIS 287
SAMPLE TREATMENT REGIMENS 287
Suggested Reading 287
CHAPTER 62 Inflammatory Airway Disease in Racehorses 288
HISTORY 288
CLINICAL EXAMINATION 289
ADDITIONAL DIAGNOSTIC PROCEDURES 289
TREATMENT 290
PROGNOSIS 291
PREVENTION 291
Suggested Reading 291
CHAPTER 63 Pleuropneumonia 292
CLINICAL SIGNS AND DIAGNOSIS 292
TREATMENT 293
PROGNOSIS 296
Suggested Reading 296
CHAPTER 64 Granulomatous lung Disease 297
CLINICAL SIGNS 297
DIAGNOSIS 297
TREATMENT 298
Suggested Reading 298
CHAPTER 65 Equine Multinodular Pulmonary Fibrosis 299
SIGNALMENT AND CLINICAL FINDINGS 299
PATHOLOGY 300
EQUINE HERPESVIRUS-5 AND EQUINE MULTINODULAR PULMONARY FIBROSIS 300
GAMMAHERPESVIRUSES AND LUNG FIBROSIS 300
DIAGNOSIS 301
TREATMENT 301
PROGNOSIS 301
SUMMARY 302
Suggested Reading 302
CHAPTER 66 The Silicosis and Osteoporosis Syndrome 303
ETIOPATHOGENESIS 303
GEOGRAPHIC DISTRIBUTION 304
HISTORY AND SIGNALMENT 304
CLINICAL SIGNS 304
DIAGNOSIS 305
TREATMENT 306
Suggested Reading 306
CHAPTER 67 Respiratory Fungal Infections 307
CLINICAL SIGNS 307
DIAGNOSIS 307
DIAGNOSTIC TESTS 307
ETIOLOGIC AGENTS 308
TREATMENT AND PROGNOSIS 312
Suggested Reading 312
CHAPTER 68 Pneumothorax 313
CLINICAL SIGNS AND DIAGNOSIS 313
TREATMENT 314
PROGNOSIS 314
Suggested Reading 314
CHAPTER 69 Thoracoscopically guided Pulmonary Biopsy 315
TECHNIQUE FOR LUNG BIOPSY 315
COMPLICATIONS 316
Suggested Reading 316
CHAPTER 70 Management of Pulmonary Edema 317
PATHOGENESIS 317
CLINICAL SIGNS 318
DIAGNOSIS 318
TREATMENT 318
Suggested Reading 319
CHAPTER 71 Exercise-Induced Pulmonary Hemorrhage 320
RISK FACTORS 320
EFFECT ON RACING PERFORMANCE 320
ETIOLOGY 320
CLINICAL SIGNS 321
DIAGNOSIS 321
TREATMENT 321
Suggested Reading 323
SECTION VIII The Gastrointestinal System 324
CHAPTER 72 Iatrogenic Damage Caused by modern Dentistry Procedures 324
NORMAL DENTAL ANATOMY 324
REDUCTION OF ABNORMAL TOOTH OVERGROWTHS 325
THERMAL DAMAGE AND EXPOSURE OF SENSITIVE TOOTH STRUCTURES 326
TRAUMA TO SOFT TISSUES 327
CONCLUSION 327
Suggested Reading 327
CHAPTER 73 Periodontal Disease 328
ANATOMY 328
ORAL CAVITY FLORA 329
IMMUNE RESPONSE 329
PATHOGENESIS 329
EXAMINATION AND DIAGNOSIS 330
INCISOR PERIODONTAL DISEASE 332
CANINE TEETH 333
PREMOLARS AND MOLARS 333
Suggested Reading 334
CHAPTER 74 Dental nerve Blocks 335
TRIGEMINAL NERVE 335
MAXILLARY NERVE 335
GREATER PALATINE NERVE 337
MANDIBULAR NERVE 337
INFERIOR ALVEOLAR NERVE 338
COMPLICATIONS 338
Suggested Reading 338
CHAPTER 75 Dental Extraction 339
INCISOR REMOVAL 339
REMOVAL OF CANINE TEETH 339
EXTRACTION OF WOLF TEETH 340
EXTRACTION OF DECIDUOUS PREMOLARS 340
EXTRACTION OF PERMANENT PREMOLARS AND MOLARS 340
DENTAL EXTRACTION UNDER GENERAL ANESTHESIA 342
TECHNIQUE FOR ORAL EXTRACTION 342
AFTERCARE 343
COMPLICATIONS 343
Suggested Reading 344
CHAPTER 76 Management of Tongue Injuries 345
TRAUMATIC INJURIES 345
PENETRATING FOREIGN BODIES 346
NEUROGENIC TONGUE INJURY 347
Suggested Reading 347
CHAPTER 77 Oral Cavity Masses 348
NEOPLASIA 348
HAMARTOMA 349
GINGIVAL HYPERPLASIA 349
EPULIS 349
EXUBERANT GRANULATION TISSUE 349
ABSCESS 349
SALIVARY DUCT CYSTS, MUCOCELES, AND RANULAS 349
ORAL CAVITY CYSTS 349
AMYLOIDOSIS 350
LAMPUS 350
Suggested Reading 350
CHAPTER 78 Esophageal Obstruction 351
ANATOMY 351
ETIOLOGY 351
CLINICAL SIGNS 351
DIAGNOSIS 351
TREATMENT 352
COMPLICATIONS 353
PREVENTION 353
Suggested Reading 353
CHAPTER 79 Dysphagia of Neurogenic origin 354
CLINICAL SIGNS 354
CLINICAL PATHOLOGY 355
DIAGNOSIS 356
TREATMENT 356
Suggested Reading 357
CHAPTER 80 Esophageal Surgery 358
APPROACHES TO THE ESOPHAGUS 358
ESOPHAGOTOMY 358
ESOPHAGOSTOMY 358
RESECTION AND ANASTOMOSIS 359
SURGERY FOR ESOPHAGEAL STENOSIS OR STRICTURE 359
SURGERY FOR ESOPHAGEAL DIVERTICULUM 359
AFTERCARE 359
Suggested Reading 360
CHAPTER 81 Grass Sickness 361
EPIDEMIOLOGY 361
ETIOLOGY 361
CLINICAL SIGNS 362
ANTEMORTEM DIAGNOSIS 363
PATHOLOGY 364
TREATMENT AND PROGNOSIS 364
Suggested Reading 365
CHAPTER 82 Gastric Ulcer Syndrome 366
PATHOGENESIS 366
CLINICAL SYNDROMES 367
DIAGNOSIS 368
TREATMENT 369
Suggested Reading 371
CHAPTER 83 Imaging, Endoscopy, and other Diagnostic Procedures for the Acute Abdomen 372
ROUTINE DIAGNOSTIC PROCEDURES 372
DIAGNOSTIC IMAGING 373
GASTROINTESTINAL ENDOSCOPY 375
Suggested Reading 376
CHAPTER 84 Stabilizing the Horse with Surgical Colic for Referral 377
TIMING IS EVERYTHING 377
INDICATIONS FOR SURGERY 377
WHEN IS IT TOO LATE? 378
CLIENT COMMUNICATIONS 378
STABILIZING THE HORSE 378
OTHER CONSIDERATIONS 380
Suggested Reading 381
CHAPTER 85 Use of Laparoscopy in Abdominal Disease 382
EQUIPMENT, INSTRUMENTATION, AND TECHNIQUE 382
ADVANTAGES AND DISADVANTAGES OF LAPAROSCOPY 383
PROCEDURES 383
CONCLUSION 385
Suggested Reading 385
CHAPTER 86 Multimodal Pain Management of the Horse with Acute Abdomen 386
ANALGESICS 386
MANAGEMENT OF ACUTE SURGICAL PAIN 387
INTRAOPERATIVE PAIN MANAGEMENT 388
PAIN MANAGEMENT IN THE RECOVERY STALL 388
Suggested Reading 388
CHAPTER 87 Gastrointestinal Prokinetic Drugs 389
LOCAL ANESTHETICS 389
CHOLINERGIC AGONISTS 391
5-HYDROXYTRYPTAMINE RECEPTOR AGONISTS 392
MOTILIN AGONISTS 392
SUMMARY 393
Suggested Reading 393
CHAPTER 88 Medical Management of Horses After Colic Surgery 394
MONITORING 394
TREATMENT 397
POSTOPERATIVE COMPLICATIONS 399
Suggested Reading 401
CHAPTER 89 Ileal Impaction 402
ETIOLOGY 402
CLINICAL SIGNS 402
TREATMENT 403
PROGNOSIS 403
Suggested Reading 404
CHAPTER 90 Cecal Impaction 405
PRIMARY CECAL IMPACTIONS 405
SECONDARY CECAL IMPACTIONS 405
SURGICAL PROCEDURES FOR CECAL IMPACTION 405
PROGNOSIS 406
Suggested Reading 406
CHAPTER 91 Intraluminal Obstruction of the Large Colon 407
INGESTA IMPACTION 407
SAND IMPACTION 410
ENTEROLITH IMPACTION 411
Suggested Reading 412
CHAPTER 92 Extraluminal Obstruction of the Large Colon 413
LARGE COLON DISPLACEMENTS 413
LARGE COLON VOLVULUS 415
LARGE COLON STENOSIS 417
LARGE COLON HERNIATION 417
Suggested Reading 417
CHAPTER 93 Acute Equine Colitis 418
PATHOPHYSIOLOGY AND CLINICAL SIGNS 418
CLINICAL EVALUATION 419
LABORATORY TESTS 420
DETERMINATION OF AN ETIOLOGY 420
TREATMENT 421
RECOVERY AND PROGNOSIS 423
Suggested Reading 423
CHAPTER 94 Chronic Colic: Diagnosis and Treatment 424
DIAGNOSIS 424
TREATMENT 428
Suggested Reading 429
CHAPTER 95 Right Dorsal Ulcerative Colitis 430
CLINICAL SIGNS 430
DIAGNOSIS 430
THERAPY 430
Suggested Reading 432
CHAPTER 96 Antibiotic-Associated Diarrhea 433
CLINICAL SIGNS 433
DIAGNOSTIC TESTING 434
TREATMENT 434
PROGNOSIS 435
Suggested Reading 435
CHAPTER 97 Mesh Hernioplasty 436
ABDOMINAL INCISIONAL HERNIA 436
MESH IMPLANT BIOLOGY 436
MESH IMPLANTATION 437
COMPLICATIONS 438
Suggested Reading 438
CHAPTER 98 Infiltrative Bowel Diseases 439
GRANULOMATOUS ENTERITIS 439
LYMPHOCYTIC-PLASMACYTIC ENTEROCOLITIS 440
MULTISYSTEMIC EOSINOPHILIC EPITHELIOTROPIC DISEASE 440
IDIOPATHIC FOCAL EOSINOPHILIC ENTEROCOLITIS 441
INTESTINAL LYMPHOMA 441
LARVAL CYATHOSTOMIASIS 442
INTESTINAL TUBERCULOSIS 442
Suggested Reading 442
CHAPTER 99 Integrated Control of Equine Cyathostomes 443
CLINICAL SIGNS OF CYATHOSTOMIASIS 444
TREATMENT 444
TOOLS FOR INTEGRATED PARASITE CONTROL 444
DESIGNING INTEGRATED CONTROL PROGRAMS 446
Suggested Reading 447
CHAPTER 100 neoplastic Disease of the Gastrointestinal Tract 448
CLINICAL SIGNS 448
DIAGNOSIS 448
TREATMENT 449
Suggested Reading 450
CHAPTER 101 Management of Rectal Tears 451
CAUSES OF RECTAL TEARS 451
DIAGNOSIS 451
TREATMENT 452
PROGNOSIS 455
LEGAL ISSUES 455
Suggested Reading 455
CHAPTER 102 Icterus 456
BILIRUBIN METABOLISM 456
ICTERUS ASSOCIATED WITH SIMPLE ANOREXIA 456
IDIOPATHIC HYPERBILIRUBINEMIA 456
ICTERUS IN NEONATAL FOALS 456
ICTERUS ASSOCIATED WITH BODY CAVITY HEMORRHAGE OR BLOOD TRANSFUSION 457
ICTERUS ASSOCIATED WITH HEPATIC DISEASE 457
ICTERUS ASSOCIATED WITH HEMOLYTIC DISEASE 457
DIFFERENTIATION OF ICTERUS CAUSED BY HEMOLYSIS FROM ICTERUS CAUSED BY LIVER DISEASE 457
TREATMENT OF ICTERUS CAUSED BY LIVER DISEASE 458
TREATMENT OF ICTERUS CAUSED BY HEMOLYTIC DISEASE 459
Suggested Reading 460
SECTION IX The Musculoskeletal System 461
CHAPTER 103 Heritable Muscle Diseases 461
HYPERKALEMIC PERIODIC PARALYSIS 461
GLYCOGEN BRANCHING ENZYME DEFICIENCY 462
POLYSACCHARIDE STORAGE MYOPATHY 463
RECURRENT EXERTIONAL RHABDOMYOLYSIS 465
MALIGNANT HYPERTHERMIA 468
Suggested Reading 468
CHAPTER 104 Evaluation of Back Pain by Clinical Examination 469
CLINICAL EVALUATION 470
IMAGING 472
Suggested Reading 473
CHAPTER 105 STRUCTURE AND FIT OF THE SADDLE 474
STRUCTURE AND FIT OF THE SADDLE 474
SIGNS OF POOR SADDLE FIT 475
ASSESSMENT OF SADDLE FIT 476
SOLUTIONS TO SADDLE FIT PROBLEMS 477
Suggested Reading 478
CHAPTER 106 Vertebral Facet Joint Syndrome 479
CLINICAL SIGNS 479
IMAGING 480
TREATMENT 481
Suggested Reading 482
CHAPTER 107 Sacroiliac Disease 483
CLINICAL EXAMINATION 483
TREATMENT 486
Suggested Reading 486
CHAPTER 108 Pelvic Fractures 488
ANATOMY 488
ETIOLOGY 488
CLINICAL SIGNS 488
DIAGNOSIS 489
TREATMENT 490
PROGNOSIS 490
Suggested Reading 491
CHAPTER 109 Musculoskeletal Injuries in the Western Performance Horse 492
TEAM ROPING 492
BARREL RACING 493
CUTTING HORSES 493
Suggested Reading 494
CHAPTER 110 Diagnostic Imaging and Surgical Management of Conditions Involving the Stifle Joint 495
IMAGING MODALITIES 495
IDENTIFICATION AND TREATMENT OF STIFLE LESIONS 497
Suggested Reading 499
CHAPTER 111 Ultrasound of the Shoulder 500
TECHNIQUE 500
ULTRASOUND-GUIDED PROCEDURES 505
Suggested Reading 505
CHAPTER 112 Hypochoeris radicata–Associated Stringhalt 506
CLINICAL SIGNS 506
DIAGNOSIS 506
TREATMENT 506
PROGNOSIS 507
Suggested Reading 507
CHAPTER 113 Osteoarthritis 508
CLINICAL SIGNS AND DIAGNOSIS 508
THERAPY 509
Suggested Reading 511
CHAPTER 114 Osteochondrosis 512
PATHOGENESIS 512
CLINICAL FINDINGS 513
THE FUTURE 517
Suggested Reading 517
CHAPTER 115 Management of Tendon Injuries 518
ANTI-INFLAMMATORY THERAPY 519
CONTROLLED EXERCISE 519
STEM CELL THERAPY 519
GROWTH FACTORS 521
PLATELET-RICH PLASMA 521
SCAFFOLD-BASED APPROACH (ACELL VET POWDER) 522
EXTRACORPOREAL SHOCK-WAVE THERAPY 522
SURGICAL OPTIONS 523
CONCLUSIONS 523
Suggested Reading 523
CHAPTER 116 Extracorporeal Shock-Wave Therapy and Radial Pressure-Wave Therapy 524
SHOCK-WAVE GENERATORS 524
RADIAl PRESSURE-WAVE GENERATORS 526
EQUIPMENT SElECTION 527
UPDATE ON APPlICATIONS OF SHOCK-WAVE THERAPY IN HORSES 527
POTENTIAl COMPlICATIONS 528
Suggested Reading 528
Websites 528
CHAPTER 117 Regional Limb Perfusion with Antimicrobials 529
INDICATIONS 530
TECHNIQUE 530
COMPLICATIONS 530
Suggested Reading 530
CHAPTER 118 White line disease 532
ETIOLOGY 532
DIAGNOSIS 532
TREATMENT 533
Suggested Reading 534
CHAPTER 119 PASTERN AND HEEL BULB LACERATIONS 535
PASTERN AND HEEL BULB LACERATIONS 535
HOOF-WALL AVULSION INJURIES 537
PUNCTURE WOUNDS 539
CONCLUSION 540
Suggested Reading 540
CHAPTER 120 Pathogenesis of Laminitis 541
SEPSIS-RELATED LAMINITIS 541
LAMINITIS DUE TO EXCESSIVE FORCE 542
OBESITY, INSULIN RESISTANCE, METABOLIC SYNDROME 542
Suggested Reading 542
CHAPTER 121 Pharmacologic Management of Laminitis 543
ANTI-INFLAMMATORY MEDICATIONS 543
SYSTEMIC AND LOCAL ANALGESIA 544
USE OF VASOACTIVE DRUGS 545
Suggested Reading 546
CHAPTER 122 Prevention of Pasture-Associated Laminitis 547
CARBOHYDRATES IN PASTURE PLANTS 547
EQUINE CARBOHYDRATE DIGESTION AND METABOLISM 547
CAUSES OF PASTURE-ASSOCIATED LAMINITIS 547
COUNTERMEASURES TO PASTURE-ASSOCIATED LAMINITIS 548
Suggested Reading 549
CHAPTER 123 Chronic Laminitis 550
PATHOPHYSIOLOGY OF CHRONIC LAMINITIS 550
PRESENTATION, DIAGNOSIS, AND EVALUATION 551
RADIOLOGY 551
OUTCOME AND PROGNOSIS 552
TREATMENT 552
TREATMENT FAILURE 559
Suggested Reading 560
CHAPTER 124 Ultrasound of the Distal Portion of the Limb 561
PREPARATION OF THE HORSE AND LIMB 561
STRUCTURES OF THE DISTAL PORTION OF THE LIMB 562
Suggested Reading 566
CHAPTER 125 Diagnostic Value of Magnetic Resonance Imaging in Horses with Foot Pain 567
BRIEF OVERVIEW OF MRI PHYSICS 567
DISTRIBUTION OF TISSUE INJURIES WITHIN THE FOOT 570
MULTIPLE INJURIES 571
PROGNOSIS FOR MRI-IDENTIFIED LESIONS 572
CONCLUSION 572
Suggested Reading 572
CHAPTER 126 PATHOLOGIC CHANGES 573
PATHOLOGIC CHANGES 573
CLINICAL EXAMINATION 573
IMAGING MODALITIES 574
TREATMENT 577
OUTCOME 578
CONCLUSION 578
CHAPTER 127 Deep Digital Flexor Tendon Injuries in the Foot 579
ANATOMY AND JUNCTION OF THE DDFT 579
PATHOPHYSIOLOGY 579
PATHOLOGY 579
CLINICAL EXAMINATION 580
IMAGING MODALITIES 581
TREATMENT AND OUTCOME 584
CONCLUSION 584
Suggested Reading 584
CHAPTER 128 ossification of the Cartilages of the Foot (Sidebone) 586
PREVALENCE OF OSSIFICATION 586
FUNCTIONS OF THE CARTILAGES OF THE FOOT 586
OSSIFICATION OF THE CARTILAGES of the foot AND LAMENESS 587
SCINTIGRAPHY AND OSSIFICATION OF THE CARTILAGES OF THE FOOT 587
CLINICAL AND RADIOGRAPHIC ASSESSMENT 588
FRACTURE OF AN OSSIFIED CARTILAGE OF THE FOOT 588
OSSEOUS TRAUMA OF THE DISTAL PHALANX DISTAL TO AN OSSIFIED CARTILAGE 590
TRAUMA TO THE UNION OF SEPARATE CENTERS OF OSSIFICATION 591
INFECTION OF A CARTILAGE OF THE FOOT 592
CONCLUSIONS 592
Suggested Reading 592
CHAPTER 129 Rehabilitation Therapy 593
MECHANICAL WAVE AGENT-THERAPEUTIC ULTRASOUND 593
ELECTRIC CURRENTS 594
ELECTROMAGNETIC WAVES 595
THE EQUINE THERAPIST ON STAFF 596
Suggested Reading 596
SECTION X The Nervous System 598
CHAPTER 130 making a Neuroanatomic Diagnosis 598
DEFINITION OF THE DISCRETE COMPONENTS OF THE INTRACRANIAL REGION 598
GENERAL CLINICAL SIGNS OF SPINAL CORD DYSFUNCTION 600
GENERAL CLINICAL SIGNS OF NEUROMUSCULAR SYSTEM DYSFUNCTION 602
Suggested Reading 602
CHAPTER 131 Diagnostic Imaging in Neurologic Disease 603
SKULL 603
CERVICAL PORTION OF THE VERTEBRAL COLUMN 604
Suggested Reading 608
CHAPTER 132 Ataxia 609
INTRACRANIAL CONDITIONS 609
CONDITIONS INVOLVING THE SPINAL CORD 609
CERVICAL VERTEBRAL STENOTIC MYELOPATHY 609
VERTEBRAL FACET ARTHRITIS 612
VERTEBRAL BODY OSTEOMYELITIS 613
VERMINOUS MYELITIS 613
EQUINE PROTOZOAL MYELOENCEPHALITIS 613
Suggested Reading 614
CHAPTER 133 Equine Motor Neuron Disease 615
CLINICAL FINDINGS 615
LABORATORY FINDINGS AND DIAGNOSIS 615
TREATMENT 616
PROGNOSIS 616
PREVENTION 616
Suggested Reading 616
CHAPTER 134 Alphaviral Encephalomyelitis (EEE, WEE, VEE) 618
HISTORY AND DISTRIBUTION 618
NATURAL HISTORY 618
CLINICAL SIGNS 619
LABORATORY FINDINGS 619
DIAGNOSIS 620
TREATMENT 620
NECROPSY FINDINGS 620
CONTROL 620
Suggested Reading 621
CHAPTER 135 West Nile Encephalitis 622
HISTORY AND DISTRIBUTION 622
NATURAL HISTORY 622
CLINICAL SIGNS 623
LABORATORY FINDINGS 623
DIAGNOSIS 624
TREATMENT 624
NECROPSY FINDINGS 624
CONTROL 625
Suggested Reading 625
CHAPTER 136 Equine Protozoal Myeloencephalitis 626
ETIOLOGY AND LIFE CYCLE 626
EPIDEMIOLOGY 626
PATHOGENESIS 626
CLINICAL SIGNS 627
DIAGNOSIS 627
TREATMENT 628
PROGNOSIS 629
PREVENTION 629
Suggested Reading 629
CHAPTER 137 Atypical Myopathy 630
EPIDEMIOLOGY, RISK FACTORS, AND SUSPECTED CAUSES 630
DIAGNOSIS 631
PREVENTION AND THERAPY 633
PROGNOSIS 634
Suggested Reading 634
SECTION XI The Eye 635
CHAPTER 138 Equine Recurrent Uveitis 635
CLINICAL SIGNS 635
PATHOGENESIS 635
DIAGNOSIS 636
TREATMENT 636
LONG-TERM PROGNOSIS 637
Suggested Reading 638
CHAPTER 139 Ocular Squamous Cell Carcinoma 639
EXAMINATION AND DIAGNOSTIC PROCEDURES 639
TREATMENT 640
SUMMARY 643
Suggested Reading 644
CHAPTER 140 Eosinophilic Keratoconjunctivitis 645
HISTORY AND CLINICAL SIGNS 645
DIAGNOSIS 645
MANAGEMENT 646
Suggested Reading 647
CHAPTER 141 Medical and Surgical Therapies for Ulcerative Keratitis 648
TREATING THE EQUINE CORNEA 648
MEDICAL TREATMENT OF CORNEAL ULCERS 649
SURGICAL TREATMENT OF CORNEAL ULCERS 650
Suggested Reading 651
CHAPTER 142 Complications of Chronic Ocular Disease 652
MEDICAL TREATMENT 652
SURGICAL THERAPY 654
Suggested Reading 654
CHAPTER 143 Enucleation 655
ENUCLEATION AND ORBITAL PROSTHESIS 655
ENUCLEATION IN THE STANDING HORSE 657
SURGICAL CLOSURE OF ENUCLEATION 658
POSTOPERATIVE CARE 658
Suggested Reading 658
CHAPTER 144 Intraocular Surgery 659
CATARACTS 659
LENS LUXATION 661
INTRAOCULAR FOREIGN BODIES 662
Suggested Reading 663
CHAPTER 145 Acute Care of Soft Tissue Injuries Involving the Eyelids, Ears, and Face 664
EYELIDS 664
EARS 665
FACE 665
LIPS 666
NOSTRILS 667
Suggested Reading 667
CHAPTER 146 Electrodiagnostic Testingfor for Retinal Disease 668
TECHNICAL ASPECTS OF ELECTRORETINOGRAPHY 668
THE ELECTRORETINOGRAM IN CLINICALLY NORMAL HORSES 670
CLINICAL INDICATIONS FOR ELECTRORETINOGRAPHY 670
Suggested Reading 671
SECTION XII The Integument 672
CHAPTER 147 Topical Treatments for Skin Disease 672
TOPICAL FORMULATIONS 672
INGREDIENTS 673
USES OF TOPICAL TREATMENTS 674
Suggested Reading 677
CHAPTER 148 Insect Hypersensitivities 678
CLINICAL SIGNS 678
DIAGNOSIS 678
TREATMENT 679
Suggested Reading 680
CHAPTER 149 Non-neoplastic Nodular and Proliferative lesions 681
DIAGNOSIS 681
EXUBERANT GRANULATION TISSUE 682
EOSINOPHILIC GRANULOMA 682
CYSTS 683
HABRONEMIASIS 684
FUNGAL GRANULOMA 684
OTHER GRANULOMAS 684
BACTERIAL PSEUDOMYCETOMA (BOTRYOMYCOSIS) 685
PSEUDOLYMPHOMA 685
CALCINOSIS CIRCUMSCRIPTA 685
NODULAR AURICULAR CHONDROPATHY 685
OTHER LESIONS 685
Suggested Reading 686
Acknowledgments 686
CHAPTER 150 Fungal Skin Diseases 687
SUPERFICIAL FUNGAL INFECTIONS OF THE SKIN 687
SUBCUTANEOUS FUNGAL INFECTIONS 689
SYSTEMIC FUNGAL INFECTIONS 691
TAPE CYTOLOGY 691
Suggested Reading 691
CHAPTER 151 Skin Tumors 692
DIAGNOSIS 692
SARCOID 693
SQUAMOUS CELL CARCINOMA 694
MELANOCYTIC TUMORS 694
TREATMENT 695
Suggested Reading 697
CHAPTER 152 New Developments in Diagnosis and Treatment of Equine Sarcoid 698
SITE PREDILECTION 698
MALIGNANT TRANSFORMATION 698
VIRAL ETIOLOGY 699
DIAGNOSIS OF EQUINE SARCOID 699
TREATMENT 700
PREVENTION 702
Suggested Reading 702
CHAPTER 153 Chronic Progressive Lymphedema in draft Horses 703
CLINICAL SIGNS 703
DIAGNOSIS 704
TREATMENT 704
Suggested Reading 705
CHAPTER 154 CLINICAL PRESENTATION 706
CLINICAL PRESENTATION 706
DIAGNOSIS 706
TREATMENT 706
GENETICS 706
Suggested Reading 708
CHAPTER 155 Cutaneous Manifestations of Systemic Disease* 709
HEREDITARY DISEASES 709
ACQUIRED DISEASES 710
Suggested Reading 712
CHAPTER 156 INITIAL ASSESSMENT 713
INITIAL ASSESSMENT 713
WOUND PREPARATION AND EVALUATION 714
SELECTION OF TREATMENT PLAN 715
ADDITIONAL CONSIDERATIONS 716
SUMMARY 717
Suggested Reading 717
CHAPTER 157 Management of Wounds in High-Motion Areas 718
HEEL BULB AND PASTERN AND FETLOCK LACERATIONS 718
WOUNDS OVER PROXIMAL JOINTS 719
HEAD WOUNDS 719
Suggested Reading 720
CHAPTER 158 Skin Grafting 721
TYPES OF GRAFTS 721
GRAFT PHYSIOLOGY 721
PREPARATION OF THE WOUND BED 722
PREPARATION OF THE DONOR SITE 722
PREPARATION OF THE RECIPIENT SITE 724
POSTOPERATIVE WOUND MANAGEMENT 725
SUMMARY 725
Suggested Reading 726
SECTION XIII The Endocrine System 727
CHAPTER 159 Insulin Resistance and Equine Metabolic Syndrome 727
CLINICAL PRESENTATION 727
PATHOPHYSIOLOGY 728
TESTING FOR INSULIN RESISTANCE 729
MANAGING OBESITY 729
MANAGING INSULIN RESISTANCE 730
RELATIONSHIP WITH PITUITARY PARS INTERMEDIA DYSFUNCTION 730
USE OF LEVOTHYROXINE SODIUM 730
Suggested Reading 731
CHAPTER 160 Pituitary Pars Intermedia Dysfunction 732
PATHOPHYSIOLOGY 732
EPIDEMIOLOGY 732
CLINICAL SIGNS 733
CLINICOPATHOLOGIC FINDINGS 733
DIAGNOSIS 733
TREATMENT 734
PROGNOSIS 735
Suggested Reading 735
CHAPTER 161 Thyroid Disease 736
THYROID GLAND NEOPLASIA 736
HYPERTHYROIDISM 736
HYPOTHYROIDISM 737
NONTHYROIDAL ILLNESS SYNDROME 737
THYROID HORMONE SUPPLEMENTATION IN ADULT HORSES 738
THYROID FUNCTION IN NORMAL NEONATAL FOALS 738
CONGENITAL HYPOTHYROIDISM: GOITER 739
CONGENITAL HYPOTHYROIDISM—WESTERN SYNDROME 739
PREMATURITY AND THYROID FUNCTION 740
Suggested Reading 740
SECTION XIV The Urogenital System 741
CHAPTER 162 Management of Bladder Uroliths 741
CLINICAL SIGNS 741
DIAGNOSIS 741
PREOPERATIVE PREPARATION 742
SELECTION OF OPERATIVE TECHNIQUE 742
SURGICAL PROCEDURES 742
LONG-TERM MANAGEMENT 744
Suggested Reading 744
CHAPTER 163 Hematuria 745
DIAGNOSIS 745
TREATMENT AND PROGNOSIS 746
Suggested Reading 747
CHAPTER 164 Clinical Pathology of Renal Disease 748
SERUM BIOCHEMISTRY 748
Suggested Reading 752
CHAPTER 165 Diseases of the Accessory Sex Glands of the Stallion 753
BACTERIAL INFECTIONS 753
NEOPLASIA 754
SPERMIOSTASIS 754
EQUINE VIRAL ARTERITIS 754
Suggested Reading 755
CHAPTER 166 Inguinal Hernia 756
CONGENITAL INGUINAL HERNIA 756
ACQUIRED INGUINAL HERNIA 758
PROGNOSIS 759
Suggested Reading 759
CHAPTER 167 Diseases of the External genitalia of Stallions 760
TRAUMATIC INJURIES 760
INFLAMMATORY CONDITIONS 761
GENITAL NEOPLASMS AND TUMOR-LIKE LESIONS 762
TESTICULAR TORSION 763
Suggested Reading 763
CHAPTER 168 Conditions of the External Genitalia of Mares 764
EXAMINATION OF THE PERINEUM 764
CASLICK’S INDEX 765
CASLICK SUTURE 765
PERINEAL LACERATIONS 765
RECTOVAGINAL FISTULAS 766
VARICOSITIES 766
INFECTIOUS DISEASES OF THE EXTERNAL GENITALIA 766
NEOPLASIA 766
CONGENITAL PROBLEMS 767
Suggested Reading 768
CHAPTER 169 Diseases of the Uterus 769
REPRODUCTIVE EXAMINATION OF THE NONPREGNANT MARE 769
ENDOMETRITIS 770
SEXUALLY TRANSMITTED UTERINE DISEASES 772
OTHER POTENTIALLY SEXUALLY TRANSMITTED BACTERIA 772
ENDOMETRIOSIS 772
VENTRAL SACCULATIONS 773
ENDOMETRIAL CYSTS 773
TRANSLUMINAL ADHESIONS 774
PYOMETRA 774
NEOPLASMS 774
UTERINE LACERATIONS 775
UTERINE ARTERY RUPTURE 775
Suggested Reading 776
CHAPTER 170 Prevention of Estrous Behavior in Performance Mares 777
PERSISTENT ESTRUS 777
PELVIC PAIN DURING ESTRUS 777
PNEUMOVAGINA AS A CAUSE OF PELVIC PAIN 777
HORMONAL METHODS OF ESTRUS SUPPRESSION 778
NONHORMONAL METHODS OF ESTRUS SUPPRESSION 779
Suggested Reading 780
CHAPTER 171 Ovariectomy Techniques 781
NEOPLASTIC OVARIES 781
NORMAL OVARIES 782
Suggested Reading 784
SECTION XV Reproduction 785
CHAPTER 172 Complications in the Peripartum Mare 785
PERIPARTUM PROBLEMS 785
PREPARTUM PROBLEMS 786
PROBLEMS AT PARTURITION 788
POSTPARTUM PROBLEMS 788
OTHER CONDITIONS 788
Suggested Reading 788
CHAPTER 173 Postpartum Complications in the Mare 789
NORMAL POSTPARTUM STATUS 789
EARLY RECOGNITION OF POTENTIAL PROBLEMS 789
UTERINE RUPTURE 789
PARTIAL INVERSION (INTUSSUSCEPTION) OF THE UTERINE HORN 790
UTERINE PROLAPSE 790
PERIPARTURIENT HEMORRHAGE 791
RETENTION OF THE FETAL MEMBRANES 793
TOXIC METRITIS 795
RECTOVAGINAL FISTULAS AND PERINEAL LACERATIONS 795
PERINEAL BRUISING AND VULVAR HEMATOMAS 795
VAGINAL LACERATIONS AND BLADDER PROLAPSE 795
INTESTINAL HERNIATION 796
BLADDER PROLAPSE 796
EVERSION OF THE URINARY BLADDER 796
RUPTURE OF THE URINARY BLADDER 796
RECTAL PROLAPSE 796
MISCELLANEOUS GASTROINTESTINAL COMPLICATIONS 797
POSTPARTUM ECLAMPSIA (LACTATION TETANY) 797
Suggested Reading 797
CHAPTER 174 newer Techniques for Artificial Insemination 799
EQUIPMENT 799
SEMEN DEPOSITION AND SPERM TRANSPORT 799
SPERM NUMBERS 799
ARTIFICIAL INSEMINATION WITH LOW NUMBERS OF SPERM 800
Suggested Reading 801
CHAPTER 175 Semen Collection and Shipping 802
METHODS OF SEMEN COLLECTION 802
SEMEN FILTRATION 803
COLLECTION FAILURE 803
PHARMACOLOGIC EJACULATION 804
SEMEN COLLECTION 804
SHIPPING OF SEMEN 804
Suggested Reading 805
CHAPTER 176 Embryo Transfer in Private Practice 806
STALLION AND SEMEN SELECTION 806
SELECTION OF DONOR MARES 806
RECIPIENT MARE SELECTION 807
DONOR-RECIPIENT SYNCHRONIZATION 807
EMBRYO COLLECTION 808
EMBRYO QUALITY 808
COOLED EMBRYOS FOR SHIPMENT 808
EMBRYO TRANSFER TECHNIQUE 808
Acknowledgment 810
Suggested Reading 810
CHAPTER 177 Ovarian Diseases 811
AGE, SEASON, AND NUTRITION 811
POSTPARTUM ANESTRUS 811
CHROMOSOMAL ABNORMALITIES 812
EQUINE CUSHING’S DISEASE 812
EXOGENOUS HORMONE TREATMENT 812
GnRH VACCINES 812
GRANULOSA CELL TUMOR 812
CYSTADENOMA 813
TERATOMA AND DYSGERMINOMA 813
ANOVULATORY FOLLICLES 813
LUTEAL INSUFFICIENCY 813
PERSISTENT CORPUS LUTEUM 814
SHORTENED LUTEAL PHASE (PREMATURE LUTEOLYSIS) 814
INCLUSION CYSTS AND PAROVARIAN CYSTS 814
ABERRANT BEHAVIOR 814
Suggested Reading 814
CHAPTER 178 Infertility in the Aged Mare 815
DIAGNOSTIC PROCEDURES 815
CAUSES AND TREATMENT OF CHRONIC INFERTILITY IN AGED MARES 817
ADMINISTRATION OF CORTICOSTEROIDS FOR TREATMENT OF INTRAUTERINE FLUID ACCUMULATION 822
CONCLUSION 822
Suggested Reading 823
CHAPTER 179 Pregnancy diagnosis 824
RECTAL PALPATION 824
CERVICAL EXAMINATION 824
TRANSRECTAL ULTRASONOGRAPHY 824
OTHER TESTS OF PREGNANCY 827
Suggested Reading 829
CHAPTER 180 Early Embryonic loss 830
INCIDENCE 830
ETIOLOGY 830
DIAGNOSIS 831
MANAGEMENT 831
Suggested Reading 833
CHAPTER 181 Placentitis 834
DIAGNOSIS 834
CLINICAL MANAGEMENT 835
FETAL EFFECTS, ASSESSMENT, AND CLINICAL MANAGEMENT 835
Suggested Reading 835
CHAPTER 182 Causes of Abortion 836
INFECTIOUS CAUSES OF ABORTION AND NEONATAL LOSS 836
NONINFECTIOUS CAUSES OF ABORTION OR STILLBIRTH 838
Suggested Reading 842
CHAPTER 183 Diagnostic Approach to Abortion 843
ABORTION CAUSED BY MATERNAL ILLNESS VERSUS BY FETAL INFECTION 843
GROSS EXAMINATION OF THE EQUINE FETUS AND PLACENTA 844
GENERAL SAMPLE COLLECTION TECHNIQUES 845
Suggested Reading 845
CHAPTER 184 Managing the High-Risk Pregnancy 846
DIAGNOSTIC PROCEDURES 846
MANAGEMENT 847
Suggested Reading 847
SECTION XVI The Foal 848
CHAPTER 185 Rescuing Foals during Dystocia 848
FETAL RESUSCITATION 848
EXIT 848
MONITORING RESUSCITATION 849
BIRTH RESUSCITATION 850
Suggested Reading 850
CHAPTER 186 Placental Evaluation for Assessment of Foal Problems and Maternal Reproductive Health 851
THE NORMAL PLACENTA 851
FACTORS AFFECTING PLACENTAL DEVELOPMENT AND FUNCTION 852
EFFECTS OF PLACENTAL CHANGES ON THE FETUS 853
SUMMARY 856
Suggested Reading 857
CHAPTER 187 meconium impaction 858
CLINICAL SIGNS 858
RADIOGRAPHIC DIAGNOSIS 858
TREATMENT 858
Suggested Reading 859
CHAPTER 188 Assays for Evaluation of Transfer of Passive Immunity 860
Suggested Reading 861
CHAPTER 189 The Systemic Inflammatory Response Syndrome 862
CLINICAL SIGNS 863
TREATMENT 863
FUTURE THERAPIES 865
CONCLUSION 866
Suggested Reading 866
CHAPTER 190 Management of the Sick neonatal Foal in the Field 867
HISTORY 867
CLINICAL ASSESSMENT OF A NEONATAL FOAL 867
MANAGEMENT OF THE FOAL WITH GENERALIZED WEAKNESS 867
MANAGEMENT OF THE FOAL WITH SIGNS OR RISK FACTORS OF BIRTH ASPHYXIA 868
MANAGEMENT OF COLIC AND ABDOMINAL DISTENSION IN THE FOAL 868
Suggested Reading 869
CHAPTER 191 Inflammatory Bowel diseases in Foals 870
NONINFECTIOUS CAUSES OF BOWEL INFLAMMATION 870
INFECTIOUS CAUSES OF BOWEL INFLAMMATION 871
INFLAMMATORY BOWEL DISEASE IN THE OLDER FOAL 873
THERAPEUTIC GUIDELINES FOR FOALS WITH INFLAMMATORY BOWEL DISEASE 874
Suggested Reading 875
CHAPTER 192 Examination of the Foal with Colic 876
HISTORY AND PHYSICAL EXAMINATION 876
PHYSICAL EXAMINATION 876
DIFFERENTIAL DIAGNOSIS 877
MAINTAINING FLUID VOLUME 878
DIAGNOSTIC PROCEDURES 878
SURGICAL DECISION MAKING 881
Suggested Reading 881
CHAPTER 193 Urogenital Disease in Foals 882
PATENT URACHUS 882
UMBILICAL HERNIAS 883
OMPHALITIS-OMPHALOPHLEBITIS 883
UROPERITONEUM 884
RENAL DISEASE 885
Suggested Reading 886
CHAPTER 194 Angular Limb Deformities 887
ETIOLOGY 887
DIAGNOSIS 888
TREATMENT 889
Suggested Reading 890
CHAPTER 195 Juvenile Idiopathic Epilepsy in Arabian Foals of Egyptian lineage 891
EPIDEMIOLOGY 891
CLINICAL SIGNS 891
DIAGNOSIS 891
TREATMENT 892
PROGNOSIS 893
Suggested Reading 893
SECTION XVII Miscellaneous 894
CHAPTRE 196 The Geriatric Horse 894
NORMAL AGING CHANGES 894
DISEASES OF THE AGED HORSE 895
CONCLUSION 897
Suggested Reading 897
CHAPTER 197 Diagnostic Approach to Chronic Weight Loss 898
CAUSES OF CHRONIC WEIGHT LOSS 898
DIAGNOSTIC APPROACH 900
Suggested Reading 901
CHAPTER 198 Integrative Medicine: Applications of Acupuncture 902
NEUROPHYSIOLOGIC BASIS OF ACUPUNCTURE 903
EASTERN THEORY OF ACUPUNCTURE 903
DIAGNOSTIC ACUPUNCTURE EXAMINATION 903
CLINICAL APPLICATIONS OF ACUPUNCTURE 904
CONCLUSIONS 906
Suggested Reading 907
CHAPTER 199 Stem Cell Therapy 908
STEM CELL BIOLOGY 908
SOURCES OF STEM CELLS 908
APPLICATIONS IN EQUINE PRACTICE 909
CONCLUSIONS 910
Suggested Reading 911
CHAPTER 200 Purchasing Laser Equipment 912
RESEARCHING EQUIPMENT 912
LINKS TO LASER WEBSITES 913
CHAPTER 201 Hyperbaric Oxygen Therapy 914
HISTORY OF HYPERBARIC CHAMBERS 914
PHYSICAL PRINCIPLES OF HYPERBARIC THERAPY 914
THERAPEUTIC BENEFITS OF HYPERBARIC OXYGEN THERAPY 916
COMPLICATIONS OF HYPERBARIC OXYGEN THERAPY 916
INDICATIONS FOR HYPERBARIC OXYGEN THERAPY 916
Suggested Reading 917
CHAPTER 202 maintenance of Horses in Slings 918
TYPES OF SLINGS 918
CLINICAL INDICATIONS 918
APPLICATION OF THE SLING 920
CONCLUSION 921
Suggested Reading 921
CHAPTER 203 Nursing Care of the Recumbent Horse 922
POSTURAL ADJUSTMENTS 922
STIMULUS REDUCTION AND SEDATION TO LIMIT THRASHING 922
NUTRITION AND HYDRATION 923
FLUID THERAPY 923
URINARY AND FECAL CARE AND HYGIENE 923
SKIN AND WOUND CARE 924
SLINGS AND LIFTS TO CHECK STANDING ABILITY 924
PHYSICAL AND MENTAL THERAPY 925
COMMON COMPLICATIONS 925
Suggested Reading 925
CHAPTER 204 The Exhausted Horse 926
CLINICAL SIGNS 926
CLINICOPATHOLOGICAL FINDINGS 926
TREATMENT 927
PROGNOSIS AND SEQUELAE 928
PREVENTION 929
Suggested Reading 929
CHAPTER 205 Rattlesnake Envenomation 930
ETIOLOGY AND PATHOGENESIS 930
CLINICAL SIGNS 930
DIAGNOSIS 930
TREATMENT 930
Suggested Reading 932
CHAPTER 206 Mycotoxins 933
GRAIN-ASSOCIATED MYCOTOXICOSES 933
FORAGE-ASSOCIATED MYCOTOXICOSES 934
Suggested Reading 935
CHAPTER 207 Malignant Hyperthermia 936
CLINICAL SIGNS 936
CLINICOPATHOLOGIC FINDINGS 936
DIAGNOSIS 936
TREATMENT AND PREVENTION 937
Suggested Reading 937
Appendix 1 Table of Common drugs, Approximate doses 939
Appendix 2 Clinical Pathology Reference Data 956
HEMATOLOGY (Tables 1 to 3) 956
COAGULATION TESTS 956
PROTEINS (Tables 4 and 5) 957
GASTROINTESTINAL SYSTEM INCLUDING THE LIVER 957
LIVER FUNCTION TESTING (Tables 6 to 8) 958
ELECTROLYTES AND OSMOLALITY 958
CARDIOVASCULAR SYSTEM 958
URINARY SYSTEM 959
MUSCULOSKELETAL SYSTEM 959
ENDOCRINOLOGY 959
CEREBROSPINAL FLUID 959
PERITONEAL FLUID 960
PLEURAL FLUID 960
RESPIRATORY SYSTEM CYTOLOGY 960
SYNOVIAL FLUID 960
MISCELLANEOUS TESTS 961
References 978
Color Plates 1-6 1
Color Plates 7-13 2
Color Plates 14-19 1
Color Plates 20-31 1
Index 981
Index to the Fifth Edition 1021