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Eureka: Physiology

Eureka: Physiology

Jake Mann | David Marples

(2018)

Abstract

Eureka – an innovative series for students that fully integrates core science, clinical medicine and surgery. With its engaging and authoritative text, featuring insightful clinical cases, graphic narratives, SBAs and a wealth of other learning tools, Eureka has everything students need to succeed in medicine and pass their exams.

 

Eureka – content that reflects today’s medical degree courses with their emphasis on:

  • relevance and application of core science to clinical practice
  • skills required to examine and communicate with patients
  • integrated care across primary and acute care settings

 

Eureka – 15 clinical titles, 5 science titles:

  • Clinical titles – disease-based, clinical cases, system-specific core science
  • Science titles – bedrock biomedical principles, clinical cases


Series features across titles:

  • Engaging clinical cases show how skilled clinician would work through a presentation, and put diseases and biomedical principles into patient context
  • Innovative graphic narratives bring clinical cases to life, show how to approach difficult scenarios and convey the experience of being a patient
  • Starter questions - stimulating answers to intriguing questions make learning fun 
  • Boxes highlight tips, tricks and key learning points

 

Physiology

  • First principles chapter clearly explains key concepts and mechanisms relevant to the study of medicine e.g. cell signalling mechanisms and homeostasis
  • Systems-based chapters describe the processes that underpin normal functions such as circulation, respiration and digestion, each chapter introduced by an engaging clinical case that features a unique graphic narrative
  • Self-Assessment – 80 multiple choice questions in clinical SBA format, in line with current exam format

 


Jake Mann BMedSc MBChB MRCP MAcadMEd
Department of paediatrics, University of Cambridge, UK


David Marples
University of Leeds, UK

 


Table of Contents

Section Title Page Action Price
Cover Cover
Half Title i
Title iii
Copyright iv
Contents viii
Series Editors’ Foreword v
About the Series Editors vi
About the Authors vi
Preface vii
Glossary x
Acknowledgements xiv
Chapter 1 First principles 1
Introduction 1
Levels of organisation 1
The cell 4
Cell membranes 15
Cell signalling mechanisms 20
Tissues 25
Homeostasis 29
Body fluids and their compartments 30
Chapter 2 Neuromuscular systems 39
Introduction 39
Case 1 Two days of leg weakness 40
Neurones and action potentials 42
Synapses 46
Motor control 48
Muscle structure and function 52
Autonomic nervous system 62
Chapter 3 Cardiovascular system and blood 67
Introduction 67
Case 2 Chest pain on exertion 68
Principles of circulation 69
The heart 73
Arteries and arterioles 80
Microcirculation 84
Lymphatic vessels 88
Veins 88
Coronary circulation 89
Blood pressure 91
Blood cells and the immune system 93
Chapter 4 Respiratory system 105
Introduction 105
Case 3 Laboured breathing in a premature baby 106
Properties of gases 107
Lungs, pleurae and muscles of respiration 108
Ventilation 110
Gaseous exchange 115
Gas transport in blood 120
Ventilation and perfusion 124
Control of breathing 126
Chapter 5 Renal system 131
Introduction 131
Case 4 Collapse, confusion and shortness of breath 132
Kidney structure and function 133
Filtration 135
Tubular functions 140
Regulation of body fluid volume 150
Acid–base balance 155
Micturition 160
Chapter 6 Endocrine system and reproduction 163
Introduction 163
Case 5 Excessive thirst and frequent urination 164
Case 6 Painless lump in right breast 165
Pituitary gland 166
Thyroid gland 170
Endocrine pancreas 173
Adrenal glands 177
Parathyroid glands and calcium regulation 180
Female reproductive system 182
Male reproductive system 187
Chapter 7 Gastrointestinal system 193
Introduction 193
Case 7 Abdominal pain and weeks of diarrhoea 194
Overview of gastrointestinal anatomy 195
Gastrointestinal processes 198
The enteric nervous system 201
Gastrointestinal hormones 204
The gastrointestinal immune system 204
The mouth and oesophagus 205
The stomach 208
The small intestine 213
The pancreas 223
The liver and biliary system 226
The large intestine 234
Chapter 8 Higher neural functions 239
Introduction 239
Case 8 Seizure 240
Perception: an overview 241
The visual system 244
The auditory and vestibular systems 252
The gustatory and olfactory systems 256
Perception of pain by the somatosensory system 258
Functions of the basal ganglia 261
Functions of the cerebellum 262
Functions of the limbic system 264
Functions of the cerebral cortex 265
Consciousness 267
Chapter 9 Applied physiology 269
Introduction 269
Case 9 Massive blood loss 270
Exercise 271
Thermoregulation 275
Maintenance of effective circulating volume 277
Stress 279
High altitude 279
Chapter 10 Self-assessment 283
SBA questions 283
SBA answers 291
Index 297
A 297
B 297
C 298
D 299
E 299
F 300
G 300
H 301
I 301
J 301
K 302
L 302
M 302
N 303
O 303
P 303
R 304
S 304
T 305
U 306
V 306
W 306