Menu Expand
Eureka: Biochemistry & Metabolism

Eureka: Biochemistry & Metabolism

Andrew Davison | Anna Milan | Suzannah Phillips | Lakshminarayan Ranganath

(2018)

Abstract

Eureka – an innovative series for students that fully integrates core science, clinical medicine and surgery. With its engaging and authoritative text, featuring insightful clinical cases, graphic narratives, SBAs and a wealth of other learning tools, Eureka has everything students need to succeed in medicine and pass their exams.

 

Eureka – content that reflects today’s medical degree courses with their emphasis on:

  • relevance and application of core science to clinical practice
  • skills required to examine and communicate with patients
  • integrated care across primary and acute care settings

 

Eureka – 15 clinical titles, 5 science titles:

  • Clinical titles – disease-based, clinical cases, system-specific core science
  • Science titles – bedrock biomedical principles, clinical cases


Series features across titles:

  • Engaging clinical cases show how skilled clinician would work through a presentation, and put diseases and biomedical principles into patient context
  • Innovative graphic narratives bring clinical cases to life, show how to approach difficult scenarios and convey the experience of being a patient
  • Starter questions - stimulating answers to intriguing questions make learning fun 
  • Boxes highlight tips, tricks and key learning points

 

Biochemistry & Metabolism

  • First principles chapter clearly explains the key concepts and mechanisms relevant to the study of medicine e.g. types of biochemical reaction, enzymes and cofactors
  • Systems-based chapters describe the structures such as proteins and fats and processes such as haemoglobin metabolism that underpin normal functions, each chapter introduced by an engaging clinical case that features a unique graphic narrative
  • Self-Assessment – 80 multiple choice questions in clinical SBA format, in line with current exam format

Andrew Davison
Anna Milan
Suzannah Phillips
Lakshminarayan Ranganath

University of Liverpool, UK

 

Table of Contents

Section Title Page Action Price
Cover Cover
Half Title i
Title iii
Copyright iv
Contents viii
Series Editors’ Foreword v
About the Series Editors vi
About the Authors vi
Preface vii
Glossary x
Acknowledgements xii
Chapter 1 First principles 1
Introduction 1
Overview 1
Cell structure 3
Cell membranes and the transport of molecules and ions 8
Signalling pathways 14
Enzymes and cofactors 20
Biochemical bonds and reactions 26
Body fuels 32
Chapter 2 Nucleic acids 43
Introduction 43
Case 1 Pain and swelling in a big toe 44
Nucleotides 46
Nucleotide synthesis 49
Nucleotide degradation 54
Drugs targeting nucleotide metabolism 56
Nucleic acid structure 57
Nucleic acid synthesis 60
Mutations 65
Chapter 3 Proteins 69
Introduction 69
Case 2 Seizure and lethargy in a baby 70
Amino acids 72
Protein synthesis 79
Protein structure and function 83
Protein turnover 87
Chapter 4 Carbohydrates 93
Introduction 93
Case 3 Collapsed and unresponsive 94
Chemical energy 96
Glucose breakdown 102
The pentose phosphate pathway 107
The citric acid cycle 110
Oxidative phosphorylation 112
Glycogen 116
Gluconeogenesis 119
Other fuels: fructose and galactose 121
Chapter 5 Lipids 125
Introduction 125
Case 4 Tiredness and tingling fingers 126
Lipid structures 128
Lipolysis 129
Lipogenesis 135
Ketone body metabolism 140
Cholesterol metabolism 141
Chapter 6 Haemoglobin metabolism 153
Introduction 153
Case 5 Chest pain 154
Blood cells 156
Haemoglobin structure 159
Haemoglobin synthesis 160
Haemoglobin breakdown 163
Iron homeostasis 165
Haemoglobin function 170
Disorders of haemoglobin 174
Chapter 7 Body fluid homeostasis 179
Introduction 179
Case 6 Injuries sustained in a traffic collision 180
pH 181
Systems that maintain acid–base homeostasis 182
Acid–base balance 187
Maintenance of fluid balance 191
Maintenance of electrolyte balance 194
Chapter 8 Nutrition 203
Introduction 203
Case 7 Yellow skin and diarrhoea 205
Energy balance 207
Vitamins 209
Minerals and trace elements 223
Nutrition and disease 227
Chapter 9 Self-assessment 237
SBA questions 237
SBA answers 245
Index 253
A 253
B 253
C 254
D 255
E 255
F 255
G 255
H 256
I 257
J 257
K 257
L 257
M 257
N 257
O 258
P 258
R 259
S 259
T 259
U 260
V 260
W 260
X 260
Z 260