BOOK
Eureka: Biochemistry & Metabolism
Andrew Davison | Anna Milan | Suzannah Phillips | Lakshminarayan Ranganath
(2018)
Additional Information
Book Details
Abstract
Eureka – an innovative series for students that fully integrates core science, clinical medicine and surgery. With its engaging and authoritative text, featuring insightful clinical cases, graphic narratives, SBAs and a wealth of other learning tools, Eureka has everything students need to succeed in medicine and pass their exams.
Eureka – content that reflects today’s medical degree courses with their emphasis on:
- relevance and application of core science to clinical practice
- skills required to examine and communicate with patients
- integrated care across primary and acute care settings
Eureka – 15 clinical titles, 5 science titles:
- Clinical titles – disease-based, clinical cases, system-specific core science
- Science titles – bedrock biomedical principles, clinical cases
Series features across titles:
- Engaging clinical cases show how skilled clinician would work through a presentation, and put diseases and biomedical principles into patient context
- Innovative graphic narratives bring clinical cases to life, show how to approach difficult scenarios and convey the experience of being a patient
- Starter questions - stimulating answers to intriguing questions make learning fun
- Boxes highlight tips, tricks and key learning points
Biochemistry & Metabolism
- First principles chapter clearly explains the key concepts and mechanisms relevant to the study of medicine e.g. types of biochemical reaction, enzymes and cofactors
- Systems-based chapters describe the structures such as proteins and fats and processes such as haemoglobin metabolism that underpin normal functions, each chapter introduced by an engaging clinical case that features a unique graphic narrative
- Self-Assessment – 80 multiple choice questions in clinical SBA format, in line with current exam format
Andrew Davison
Anna Milan
Suzannah Phillips
Lakshminarayan Ranganath
University of Liverpool, UK
Table of Contents
Section Title | Page | Action | Price |
---|---|---|---|
Cover | Cover | ||
Half Title | i | ||
Title | iii | ||
Copyright | iv | ||
Contents | viii | ||
Series Editors’ Foreword | v | ||
About the Series Editors | vi | ||
About the Authors | vi | ||
Preface | vii | ||
Glossary | x | ||
Acknowledgements | xii | ||
Chapter 1 First principles | 1 | ||
Introduction | 1 | ||
Overview | 1 | ||
Cell structure | 3 | ||
Cell membranes and the transport of molecules and ions | 8 | ||
Signalling pathways | 14 | ||
Enzymes and cofactors | 20 | ||
Biochemical bonds and reactions | 26 | ||
Body fuels | 32 | ||
Chapter 2 Nucleic acids | 43 | ||
Introduction | 43 | ||
Case 1 Pain and swelling in a big toe | 44 | ||
Nucleotides | 46 | ||
Nucleotide synthesis | 49 | ||
Nucleotide degradation | 54 | ||
Drugs targeting nucleotide metabolism | 56 | ||
Nucleic acid structure | 57 | ||
Nucleic acid synthesis | 60 | ||
Mutations | 65 | ||
Chapter 3 Proteins | 69 | ||
Introduction | 69 | ||
Case 2 Seizure and lethargy in a baby | 70 | ||
Amino acids | 72 | ||
Protein synthesis | 79 | ||
Protein structure and function | 83 | ||
Protein turnover | 87 | ||
Chapter 4 Carbohydrates | 93 | ||
Introduction | 93 | ||
Case 3 Collapsed and unresponsive | 94 | ||
Chemical energy | 96 | ||
Glucose breakdown | 102 | ||
The pentose phosphate pathway | 107 | ||
The citric acid cycle | 110 | ||
Oxidative phosphorylation | 112 | ||
Glycogen | 116 | ||
Gluconeogenesis | 119 | ||
Other fuels: fructose and galactose | 121 | ||
Chapter 5 Lipids | 125 | ||
Introduction | 125 | ||
Case 4 Tiredness and tingling fingers | 126 | ||
Lipid structures | 128 | ||
Lipolysis | 129 | ||
Lipogenesis | 135 | ||
Ketone body metabolism | 140 | ||
Cholesterol metabolism | 141 | ||
Chapter 6 Haemoglobin metabolism | 153 | ||
Introduction | 153 | ||
Case 5 Chest pain | 154 | ||
Blood cells | 156 | ||
Haemoglobin structure | 159 | ||
Haemoglobin synthesis | 160 | ||
Haemoglobin breakdown | 163 | ||
Iron homeostasis | 165 | ||
Haemoglobin function | 170 | ||
Disorders of haemoglobin | 174 | ||
Chapter 7 Body fluid homeostasis | 179 | ||
Introduction | 179 | ||
Case 6 Injuries sustained in a traffic collision | 180 | ||
pH | 181 | ||
Systems that maintain acid–base homeostasis | 182 | ||
Acid–base balance | 187 | ||
Maintenance of fluid balance | 191 | ||
Maintenance of electrolyte balance | 194 | ||
Chapter 8 Nutrition | 203 | ||
Introduction | 203 | ||
Case 7 Yellow skin and diarrhoea | 205 | ||
Energy balance | 207 | ||
Vitamins | 209 | ||
Minerals and trace elements | 223 | ||
Nutrition and disease | 227 | ||
Chapter 9 Self-assessment | 237 | ||
SBA questions | 237 | ||
SBA answers | 245 | ||
Index | 253 | ||
A | 253 | ||
B | 253 | ||
C | 254 | ||
D | 255 | ||
E | 255 | ||
F | 255 | ||
G | 255 | ||
H | 256 | ||
I | 257 | ||
J | 257 | ||
K | 257 | ||
L | 257 | ||
M | 257 | ||
N | 257 | ||
O | 258 | ||
P | 258 | ||
R | 259 | ||
S | 259 | ||
T | 259 | ||
U | 260 | ||
V | 260 | ||
W | 260 | ||
X | 260 | ||
Z | 260 |