BOOK
Eureka: Biochemistry & Metabolism
Andrew Davison | Anna Milan | Suzannah Phillips | Lakshminarayan Ranganath
(2018)
Additional Information
Book Details
Abstract
Eureka – an innovative series for students that fully integrates core science, clinical medicine and surgery. With its engaging and authoritative text, featuring insightful clinical cases, graphic narratives, SBAs and a wealth of other learning tools, Eureka has everything students need to succeed in medicine and pass their exams.
Eureka – content that reflects today’s medical degree courses with their emphasis on:
- relevance and application of core science to clinical practice
- skills required to examine and communicate with patients
- integrated care across primary and acute care settings
Eureka – 15 clinical titles, 5 science titles:
- Clinical titles – disease-based, clinical cases, system-specific core science
- Science titles – bedrock biomedical principles, clinical cases
Series features across titles:
- Engaging clinical cases show how skilled clinician would work through a presentation, and put diseases and biomedical principles into patient context
- Innovative graphic narratives bring clinical cases to life, show how to approach difficult scenarios and convey the experience of being a patient
- Starter questions - stimulating answers to intriguing questions make learning fun
- Boxes highlight tips, tricks and key learning points
Biochemistry & Metabolism
- First principles chapter clearly explains the key concepts and mechanisms relevant to the study of medicine e.g. types of biochemical reaction, enzymes and cofactors
- Systems-based chapters describe the structures such as proteins and fats and processes such as haemoglobin metabolism that underpin normal functions, each chapter introduced by an engaging clinical case that features a unique graphic narrative
- Self-Assessment – 80 multiple choice questions in clinical SBA format, in line with current exam format
Andrew Davison
Anna Milan
Suzannah Phillips
Lakshminarayan Ranganath
University of Liverpool, UK
Table of Contents
| Section Title | Page | Action | Price |
|---|---|---|---|
| Cover | Cover | ||
| Half Title | i | ||
| Title | iii | ||
| Copyright | iv | ||
| Contents | viii | ||
| Series Editors’ Foreword | v | ||
| About the Series Editors | vi | ||
| About the Authors | vi | ||
| Preface | vii | ||
| Glossary | x | ||
| Acknowledgements | xii | ||
| Chapter 1 First principles | 1 | ||
| Introduction | 1 | ||
| Overview | 1 | ||
| Cell structure | 3 | ||
| Cell membranes and the transport of molecules and ions | 8 | ||
| Signalling pathways | 14 | ||
| Enzymes and cofactors | 20 | ||
| Biochemical bonds and reactions | 26 | ||
| Body fuels | 32 | ||
| Chapter 2 Nucleic acids | 43 | ||
| Introduction | 43 | ||
| Case 1 Pain and swelling in a big toe | 44 | ||
| Nucleotides | 46 | ||
| Nucleotide synthesis | 49 | ||
| Nucleotide degradation | 54 | ||
| Drugs targeting nucleotide metabolism | 56 | ||
| Nucleic acid structure | 57 | ||
| Nucleic acid synthesis | 60 | ||
| Mutations | 65 | ||
| Chapter 3 Proteins | 69 | ||
| Introduction | 69 | ||
| Case 2 Seizure and lethargy in a baby | 70 | ||
| Amino acids | 72 | ||
| Protein synthesis | 79 | ||
| Protein structure and function | 83 | ||
| Protein turnover | 87 | ||
| Chapter 4 Carbohydrates | 93 | ||
| Introduction | 93 | ||
| Case 3 Collapsed and unresponsive | 94 | ||
| Chemical energy | 96 | ||
| Glucose breakdown | 102 | ||
| The pentose phosphate pathway | 107 | ||
| The citric acid cycle | 110 | ||
| Oxidative phosphorylation | 112 | ||
| Glycogen | 116 | ||
| Gluconeogenesis | 119 | ||
| Other fuels: fructose and galactose | 121 | ||
| Chapter 5 Lipids | 125 | ||
| Introduction | 125 | ||
| Case 4 Tiredness and tingling fingers | 126 | ||
| Lipid structures | 128 | ||
| Lipolysis | 129 | ||
| Lipogenesis | 135 | ||
| Ketone body metabolism | 140 | ||
| Cholesterol metabolism | 141 | ||
| Chapter 6 Haemoglobin metabolism | 153 | ||
| Introduction | 153 | ||
| Case 5 Chest pain | 154 | ||
| Blood cells | 156 | ||
| Haemoglobin structure | 159 | ||
| Haemoglobin synthesis | 160 | ||
| Haemoglobin breakdown | 163 | ||
| Iron homeostasis | 165 | ||
| Haemoglobin function | 170 | ||
| Disorders of haemoglobin | 174 | ||
| Chapter 7 Body fluid homeostasis | 179 | ||
| Introduction | 179 | ||
| Case 6 Injuries sustained in a traffic collision | 180 | ||
| pH | 181 | ||
| Systems that maintain acid–base homeostasis | 182 | ||
| Acid–base balance | 187 | ||
| Maintenance of fluid balance | 191 | ||
| Maintenance of electrolyte balance | 194 | ||
| Chapter 8 Nutrition | 203 | ||
| Introduction | 203 | ||
| Case 7 Yellow skin and diarrhoea | 205 | ||
| Energy balance | 207 | ||
| Vitamins | 209 | ||
| Minerals and trace elements | 223 | ||
| Nutrition and disease | 227 | ||
| Chapter 9 Self-assessment | 237 | ||
| SBA questions | 237 | ||
| SBA answers | 245 | ||
| Index | 253 | ||
| A | 253 | ||
| B | 253 | ||
| C | 254 | ||
| D | 255 | ||
| E | 255 | ||
| F | 255 | ||
| G | 255 | ||
| H | 256 | ||
| I | 257 | ||
| J | 257 | ||
| K | 257 | ||
| L | 257 | ||
| M | 257 | ||
| N | 257 | ||
| O | 258 | ||
| P | 258 | ||
| R | 259 | ||
| S | 259 | ||
| T | 259 | ||
| U | 260 | ||
| V | 260 | ||
| W | 260 | ||
| X | 260 | ||
| Z | 260 |