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Fundamentals of Oncologic PET/CT E-Book

Fundamentals of Oncologic PET/CT E-Book

Gary A. Ulaner

(2018)

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Book Details

Abstract

In the fast-changing age of precision medicine, PET/CT is increasingly important for accurate cancer staging and evaluation of treatment response. Fundamentals of Oncologic PET/CT, by Dr. Gary A. Ulaner, offers an organized, systematic introduction to reading and interpreting PET/CT studies, ideal for radiology and nuclear medicine residents, practicing radiologists, medical oncologists, and radiation oncologists. Synthesizing eight years’ worth of cases and lectures from one of the largest cancer centers in the world, this title provides a real-world, practical approach, taking you through the body organ by organ as it explains how to integrate both the FDG PET and CT findings to best interpret each lesion.


Table of Contents

Section Title Page Action Price
Front Cover cover
IFC_ExCon page IFC2
Fundamentals of Oncologic PET/CT i
Copyright Page iv
Dedication v
Preface vii
Table Of Contents ix
I Introduction and Fundamentals 1
1 Introduction to FDG PET/CT 1
Abstract 1.e1
Keywords 1.e1
2 FDG PET/CT Performance and Reporting 5
Abstract 5.e1
Keywords 5.e1
Performing FDG PET/CT 5
Quantifying FDG Avidity With Standardized Uptake Values 5
Reporting FDG PET/CT Examinations 6
Structured Reports 6
Conveying Diagnostic Certainty 7
PET Findings Versus CT Findings 8
Reference Lesions 8
Suggested Readings 8
II Musculoskeletal System and Body Wall 9
3 Skeleton on FDG PET/CT 9
Abstract 9.e1
Keywords 9.e1
FDG-Avid Cancer 9
Metastases 9
Lymphoma 9
Multiple Myeloma 10
Primary Osseous Sarcomas 10
Not FDG Avid and Not Cancer 12
Not FDG Avid but Cancer 14
FDG Avid but Not Cancer 14
Granulocyte Colony-Stimulating Factors 16
Degenerative Changes 17
Inflammatory Diseases 23
Fractures 23
Bone Infarcts (Avascular Necrosis of Bone) 24
Paget Disease 25
Transient Osteoporosis of the Hip 26
Benign Neoplasms 26
Nonossifying Fibromas 26
Biopsy Tracts 29
Radiation-Induced Osteoradionecrosis 30
Conclusion 32
Suggested Readings 32
4 Muscle and Nerve on FDG PET/CT 33
Abstract 33.e1
Keywords 33.e1
Conclusion 41
Suggested Readings 42
5 Skin and Breast on FDG PET/CT 43
Abstract 43.e1
Keywords 43.e1
Suggested Readings 50
III Head and Neck 51
6 Brain on FDG PET/CT 51
Abstract 51.e1
Keywords 51.e1
Normal Brain 51
Initial Detection of Brain Malignancy 51
Treatment Response of Brain Malignancy 57
Tumor Recurrence Versus Radiation Necrosis 57
Benign Intracranial Lesions 58
Infarcts and Seizures 58
Suggested Readings 62
7 Head and Neck on FDG PET/CT 63
Abstract 63.e1
Keywords 63.e1
Head and Neck Anatomy 63
Physiology FDG Avidity in the Head and Neck 66
Anatomic and Metabolic Alterations by Surgery and Chemoradiation 67
Salivary Glands 69
Thyroid Gland 69
Vocal Cords 74
Squamous Cell Carcinomas 74
Lymphoma 81
Orbit 82
Perineural Disease 83
Concurrent Pathology 83
Suggested Readings 85
IV Thorax 87
8 Lung on FDG PET/CT 87
Abstract 87.e1
Keywords 87.e1
Solitary Pulmonary Nodules 87
Multiple Pulmonary Nodules 87
Lung Cancer 87
Benign Lung Lesions With Distinct Appearances 93
Suggested Readings 98
9 Pleura on FDG PET/CT 99
Abstract 99.e1
Keywords 99.e1
Postpleurodesis Inflammation 99
Pleural Metastases 99
Pleural Mesothelioma 99
Suggested Readings 101
10 Heart on FDG PET/CT 103
Abstract 103.e1
Keywords 103.e1
Suggested Readings 107
11 Thymus Masses on FDG PET/CT 109
Abstract 109.e1
Keywords 109.e1
Suggested Readings 111
V Abdominal Solid Organs 113
12 Hepatobiliary FDG PET/CT 113
Abstract 113.e1
Keywords 113.e1
Liver 113
Hepatic Metastases 113
Lymphoma 118
Hepatocellular Carcinoma 118
Cholangiocarcinoma 118
Hepatocellular Adenoma 119
Hepatic Hemangioma 121
Hepatic Focal Nodular Hyperplasia 121
Hepatic Cysts 122
Hepatic Infections 122
Iatrogenic FDG Avidity in the Liver 122
Gallbladder 122
Gallbladder Cancer 123
Gallbladder Metastases 124
Cholecystitis 124
Suggested Readings 126
13 Spleen on FDG PET/CT 127
Abstract 127.e1
Keywords 127.e1
Splenic Lymphoma 127
Splenic Metastases 127
Primary Splenic Neoplasms 127
Granulomatosis Inflammation 127
Splenic Repopulation 129
Suggested Readings 131
14 Pancreas on FDG PET/CT 133
Abstract 133.e1
Keywords 133.e1
Solid Pancreatic Lesions 133
Pancreatic Adenocarcinoma 133
Pancreatic Neuroendocrine Tumors 133
Pancreatic Lymphoma 135
Pancreatic Metastases 136
Cystic Pancreatic Lesions 136
True Pancreatic Cysts 136
Pancreatic Pseudocysts 136
Pancreatic Cystic Neoplasms 136
Pancreatic Ductal Dilatation 137
Pancreatitis 137
Suggested Readings 141
15 Adrenal Glands on FDG PET/CT 143
Abstract 143.e1
Keywords 143.e1
Adrenal Metastases 143
Adrenal Lymphoma 143
Adrenocortical Carcinoma 143
Adenoma 143
Adrenal Pheochromocytoma 148
Myelolipoma 148
Ganglioneuroma 148
Physiologic Adrenal FDG Avidity 148
Adrenal Hyperplasia 148
Infection, Hemorrhage, and Trauma 149
Adrenal Collision Tumors 149
Suggested Readings 150
VI Gastrointestinal Tract and Peritoneum 151
16 Gastrointestinal Tract on FDG PET/CT 151
Abstract 151.e1
Keywords 151.e1
Esophagus 151
Stomach 153
Small Bowel 157
Appendix 161
Colorectal 161
Anus 165
Suggested Readings 169
17 Peritoneum on FDG PET/CT 171
Abstract 171.e1
Keywords 171.e1
Peritoneal Metastases 171
Primary Peritoneal Malignancies 171
Benign Peritoneal Processes 176
Suggested Readings 177
VII Genitourinary 179
18 Urinary Tract on FDG PET/CT (Kidneys, Ureters, Bladder) 179
Abstract 179.e1
Keywords 179.e1
Kidney 179
Renal Cell Carcinoma 179
Oncocytoma 179
Transitional Cell Carcinoma 182
Angiomyolipoma 182
Wilms Tumor 182
Renal Lymphoma 182
Renal Metastases 184
Renal Cysts 184
Renal Infections 184
Bladder 186
Bladder Cancer 186
Bladder Diverticula Versus Pericystic Nodes/Masses 187
Urachal Lesions 187
Suggested Readings 190
19 Female Pelvis on FDG PET/CT 191
Abstract 191.e1
Keywords 191.e1
Physiologic FDG Avidity in the Female Reproductive Tract 191
Ovary 191
Ovarian Cancer 191
Benign Ovarian Lesions 197
Endometrium 197
Endometrial Cancer 197
Benign Endometrial FDG Avidity 197
Myometrium 197
Myometrial Leiomyomata 197
Myometrial Leiomyosarcoma 200
Cervix 200
Cervical Carcinoma 200
Suggested Readings 203
20 Male Pelvis on FDG PET/CT 205
Abstract 205.e1
Keywords 205.e1
Testes 205
Physiologic FDG Avidity in the Testes 205
Testicular Malignancies 205
Orchitis 205
Prostate 205
Suggested Readings 210
VIII Additional Issues in FDG PET/CT 211
21 Lymph Nodes on FDG PET/CT 211
Abstract 211.e1
Keywords 211.e1
Lymphoma 211
Nodal Metastases 213
Benign FDG-Avid Nodes 213
Suggested Readings 223
22 Measuring Treatment Response on FDG PET/CT 225
Abstract 225.e1
Keywords 225.e1
Suggested Readings 229
23 Artifacts on FDG PET/CT 231
Abstract 231.e1
Keywords 231.e1
Motion 231
Attenuation Correction Artifacts 231
Partial Volume Effect Artifacts 231
Biodistribution of FDG 232
“Blooming” Of Highly Concentrated FDG 232
Suggested Readings 234
IX Radiotracers Other Than FDG for Oncologic PET/CT 235
24 Radiotracers Other Than FDG for Oncologic PET/CT 235
Abstract 235.e1
Keywords 235.e1
18F-Sodium Fluoride (Na18F) 235
68Ga-DOTATATE 236
11C-Choline 237
Fluciclovine 239
68Ga-PSMA-11 240
Conclusion 242
Suggested Readings 242
Index 243
A 243
B 243
C 243
D 244
E 244
F 244
G 244
H 245
I 245
K 245
L 245
M 246
N 246
O 246
P 246
R 247
S 247
T 248
U 248
V 248
W 248
IBC_Clinical Key ad IBC3