BOOK
Chronobiology and Cardiovascular Diseases, An Issue of Heart Failure Clinics, E-Book
(2017)
Additional Information
Book Details
Abstract
This issue of Heart Failure Clinics, edited by Dr. Roberto Manfredini, will cover an array of topics related to Chronobiology and Cardiovascular Diseases. Topics include, but are not limited to Clock genes, metabolism and cardiovascular risk; Cardiac clocks and preclinical translation; Chronobiology of arterial blood pressure; Circadian periodicity of ischemic heart disease; Seasonal periodicity of ischemic heart disease and heart failure; Chronobiologic aspects of venous thromboembolism; Chronobiologic aspects of acute aortic diseases; Circaseptan periodicity of CV diseases; Gender and periodicity of CV disease; Chronopharmacology of CV drugs; Chronotherapy of Hypertension; and Chronoprevention of CV diseases.
Table of Contents
| Section Title | Page | Action | Price |
|---|---|---|---|
| Front Cover | Cover | ||
| Chronobiology and Cardiovascular Diseases\r | i | ||
| Copyright\r | ii | ||
| Contributors | iii | ||
| CONSULTING EDITOR | iii | ||
| EDITOR | iii | ||
| AUTHORS | iii | ||
| Contents | vii | ||
| Preface: A Journey into the Science of Cardiovascular Chronobiology | vii | ||
| Clock Genes, Metabolism, and Cardiovascular Risk | vii | ||
| Cardiac Clocks and Preclinical Translation | vii | ||
| Circadian Periodicity of Ischemic Heart Disease: A Systematic Review of the Literature | vii | ||
| Seasonal Periodicity of Ischemic Heart Disease and Heart Failure | vii | ||
| Chronobiologic Aspects of Venous Thromboembolism | viii | ||
| Chronobiology of Acute Aortic Syndromes | viii | ||
| Circaseptan Periodicity of Cardiovascular Diseases | viii | ||
| Sex and Circadian Periodicity of Cardiovascular Diseases: Are Women Sufficiently Represented in Chronobiological Studies? | viii | ||
| Signal Transduction and Chronopharmacology of Regulation of Circadian Cardiovascular Rhythms in Animal Models of Human Hype ... | ix | ||
| Bedtime Blood Pressure Chronotherapy Significantly Improves Hypertension Management | ix | ||
| Bedtime Chronotherapy with Conventional Hypertension Medications to Target Increased Asleep Blood Pressure Results in Marke ... | ix | ||
| HEART FAILURE CLINICS\r | x | ||
| FORTHCOMING ISSUES | x | ||
| January 2018 | x | ||
| April 2018 | x | ||
| July 2018 | x | ||
| RECENT ISSUES | x | ||
| July 2017 | x | ||
| April 2017 | x | ||
| January 2017 | x | ||
| Erratum | xi | ||
| Preface:\rA Journey into the Science of Cardiovascular Chronobiology | xiii | ||
| REFERENCES | xiv | ||
| Clock Genes, Metabolism, and Cardiovascular Risk | 645 | ||
| Key points | 645 | ||
| INTRODUCTION | 645 | ||
| THE MOLECULAR CLOCKWORK | 646 | ||
| SIRTUINS AND THE BIOLOGICAL CLOCK | 646 | ||
| POSTTRANSLATIONAL AND EPIGENETIC MODIFICATIONS | 646 | ||
| AN AUXILIARY LOOP IN THE MOLECULAR CLOCKWORK | 647 | ||
| THE CLOCK-CONTROLLED GENES | 647 | ||
| THE BIOLOGICAL CLOCK AND THE NUCLEAR RECEPTORS | 648 | ||
| THE MOLECULAR CLOCKWORK AND INTERMEDIATE METABOLISM | 649 | ||
| Lipid Metabolism | 649 | ||
| Glucose Metabolism | 649 | ||
| THE BIOLOGICAL CLOCK AND DERANGED METABOLISM | 650 | ||
| THE CLOCK GENE MACHINERY, LIVER STEATOSIS, AND CARDIOVASCULAR DISEASE | 650 | ||
| THE BIOLOGICAL CLOCK AT THE CROSSROAD OF AUTOPHAGY, GUT MICROBIOTA, INFLAMMATION, BILE ACID SIGNALING, AND INTERMEDIATE MET ... | 651 | ||
| SUMMARY | 651 | ||
| REFERENCES | 651 | ||
| Cardiac Clocks and Preclinical Translation | 657 | ||
| Key points | 657 | ||
| INTRODUCTION | 657 | ||
| CIRCADIAN RHYTHMS IN THE CARDIOVASCULAR SYSTEM | 657 | ||
| Overview of the Circadian Mechanism in the Heart | 658 | ||
| Circadian Rhythms and Healthy Cardiovascular Physiology | 658 | ||
| Circadian Rhythms in the Timing of Onset of Adverse Cardiovascular Events | 658 | ||
| TRANSLATING CIRCADIAN RHYTHMS FOR THE TREATMENT OF HEART DISEASE | 659 | ||
| Chronotherapy Benefits Treatment of Heart Disease, Basic Research | 659 | ||
| Chronotherapy and Clinical Applications for Treatment of Heart Disease | 659 | ||
| Rhythms in the Intensive Care Unit | 659 | ||
| NEW FRONTIERS IN CARDIAC CLOCKS AND PRECLINICAL TRANSLATION | 662 | ||
| Circadian Rhythms and Cardiovascular Aging | 663 | ||
| Circadian Rhythms and Mitophagy | 665 | ||
| Circadian Rhythms and Depression in Patients with Heart Disease | 666 | ||
| SUMMARY | 666 | ||
| REFERENCES | 666 | ||
| Circadian Periodicity of Ischemic Heart Disease | 673 | ||
| Key points | 673 | ||
| INTRODUCTION | 673 | ||
| METHODS | 674 | ||
| RESULTS | 674 | ||
| DISCUSSION | 674 | ||
| LIMITATIONS | 675 | ||
| SUMMARY | 678 | ||
| REFERENCES | 678 | ||
| Seasonal Periodicity of Ischemic Heart Disease and Heart Failure | 681 | ||
| Key points | 681 | ||
| INTRODUCTION | 681 | ||
| “Look to the Seasons when Choosing Your Cures” (Hippocrates) | 681 | ||
| ISCHEMIC HEART DISEASE | 681 | ||
| Epidemiology | 681 | ||
| Influence of Influenza | 682 | ||
| Biochemical Factors | 682 | ||
| Role of Air Pollution | 682 | ||
| Effect of Temperature | 683 | ||
| HEART FAILURE | 683 | ||
| Epidemiology | 683 | ||
| Infectious Disease and Tachyarrhythmia | 683 | ||
| Hemodynamics | 684 | ||
| Effect of Weather | 685 | ||
| Effect of Air Pollution | 685 | ||
| REFERENCES | 686 | ||
| Chronobiologic Aspects of Venous Thromboembolism | 691 | ||
| Key points | 691 | ||
| INTRODUCTION | 691 | ||
| CHRONOBIOLOGY OF INCIDENCE AND MORTALITY FOR VENOUS THROMBOEMBOLIC EVENTS | 692 | ||
| Seasonal Variability | 692 | ||
| Circadian Variability | 693 | ||
| PATHOPHYSIOLOGY OF SEASONAL VARIATION OF VENOUS THROMBOEMBOLISM | 693 | ||
| DISCUSSION | 694 | ||
| REFERENCES | 694 | ||
| Chronobiology of Acute Aortic Syndromes | 697 | ||
| Key points | 697 | ||
| INTRODUCTION | 697 | ||
| REVIEW OF THE LITERATURE | 697 | ||
| PROPOSED PATHOPHYSIOLOGY | 699 | ||
| SUMMARY | 700 | ||
| REFERENCES | 700 | ||
| Circaseptan Periodicity of Cardiovascular Diseases | 703 | ||
| Key points | 703 | ||
| INTRODUCTION | 703 | ||
| CIRCASEPTAN PERIODICITY | 703 | ||
| WEEKEND EFFECT | 705 | ||
| Weekend Effect: Acute Myocardial Infarction | 705 | ||
| Weekend Effect: Stroke | 705 | ||
| Weekend Effect: Other Cardiovascular Diseases | 708 | ||
| WEEKEND EFFECT: SUMMARY | 708 | ||
| REFERENCES | 713 | ||
| Sex and Circadian Periodicity of Cardiovascular Diseases | 719 | ||
| Key points | 719 | ||
| CLINICAL TRIALS AND SEX DISPARITIES | 719 | ||
| CIRCADIAN PERIODICITY OF CARDIOVASCULAR DISEASES | 720 | ||
| ACUTE MYOCARDIAL INFARCTION | 720 | ||
| SUDDEN CARDIAC DEATH AND CARDIAC ARREST | 721 | ||
| AORTIC ANEURYSMS, RUPTURE, AND DISSECTION | 727 | ||
| CEREBROVASCULAR DISEASES | 731 | ||
| SUMMARY | 732 | ||
| ACKNOWLEDGMENTS | 734 | ||
| REFERENCES | 734 | ||
| Signal Transduction and Chronopharmacology of Regulation of Circadian Cardiovascular Rhythms in Animal Models of Human Hype ... | 739 | ||
| Key points | 739 | ||
| INTRODUCTION | 739 | ||
| TEMPORAL ASPECTS OF THE SYMPATHETIC NERVOUS SYSTEM | 740 | ||
| NOREPINEPHRINE CONTENT AND TURNOVER IN RAT HEART | 740 | ||
| THE BETA-RECEPTOR EFFECTOR SYSTEM | 743 | ||
| THE RENIN-ANGIOTENSIN-ALDOSTERONE-CORTICOSTERONE SYSTEM | 747 | ||
| THE NITRIC OXIDE SYSTEM | 747 | ||
| CIRCADIAN RHYTHMS IN CARDIOVASCULAR FUNCTION: RADIOTELEMETRY | 748 | ||
| CHRONOPHARMACOLOGY OF ANTIHYPERTENSIVE DRUGS | 753 | ||
| SUMMARY | 754 | ||
| ACKNOWLEDGMENTS | 754 | ||
| REFERENCES | 754 | ||
| Bedtime Blood Pressure Chronotherapy Significantly Improves Hypertension Management | 759 | ||
| Key points | 759 | ||
| INTRODUCTION | 760 | ||
| INGESTION-TIME DIFFERENCES IN PHARMACODYNAMICS OF HYPERTENSION MEDICATIONS | 760 | ||
| Angiotensin-Converting Enzyme Inhibitor Monotherapy | 761 | ||
| Angiotensin-II Receptor Blockers Monotherapy | 762 | ||
| Other Hypertension Monotherapies | 764 | ||
| Fixed Combination Hypertension Therapy | 764 | ||
| BEDTIME CHRONOTHERAPY FOR DIFFICULT TO CONTROL AND COMPLICATED HYPERTENSION | 765 | ||
| Resistant Hypertension | 765 | ||
| Chronic Kidney Disease | 766 | ||
| Diabetes | 767 | ||
| Non-Dipper Hypertension | 768 | ||
| SUMMARY | 769 | ||
| REFERENCES | 769 | ||
| Bedtime Chronotherapy with Conventional Hypertension Medications to Target Increased Asleep Blood Pressure Results in Marke ... | 775 | ||
| Key points | 775 | ||
| INTRODUCTION | 776 | ||
| AROUND-THE-CLOCK AMBULATORY BLOOD PRESSURE MONITORING VERSUS OFFICE BLOOD PRESSURE MONITORING IN THE DIAGNOSIS OF HYPERTENSION | 776 | ||
| SLEEP-TIME BLOOD PRESSURE: INDEPENDENT PROGNOSTIC MARKER OF CARDIOVASCULAR DISEASE RISK | 777 | ||
| THE MAPEC OUTCOMES TRIAL: VERIFICATION OF THE CRUCIAL IMPORTANCE OF ASLEEP BLOOD PRESSURE AS THE MOST SENSITIVE PREDICTOR O ... | 779 | ||
| Sleep-time Blood Pressure: Key Therapeutic Target for Cardiovascular Disease Risk Reduction | 780 | ||
| Evidence that the Chronoprevention of Cardiovascular Disease Events is Best Achieved by Bedtime Hypertension Chronotherapy | 784 | ||
| Heart Outcomes Prevention Evaluation Trial | 785 | ||
| Syst-Eur and Syst-China Trials | 785 | ||
| Controlled-onset Extended-release Verapamil Investigation of Cardiovascular Endpoints Trial | 785 | ||
| MAPEC Study | 786 | ||
| SUMMARY | 787 | ||
| REFERENCES | 789 |