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Essential Echocardiography: A Companion to Braunwald’s Heart Disease E-Book

Essential Echocardiography: A Companion to Braunwald’s Heart Disease E-Book

Scott D Solomon | Justina Wu | Linda D. Gillam

(2017)

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Book Details

Abstract

Echocardiography remains the most commonly used imaging technique to visualize the heart and great vessels, and this clinically oriented text by Drs. Scott D. Solomon, Justina C. Wu, and Linda D. Gillam helps you make the most of its diagnostic and prognostic potential for your patients. Part of the highly regarded Braunwald’s family of cardiology references, Essential Echocardiography expertly covers basic principles of anatomy and physiology, the appearance of normal variants across a wide range of cardiovascular diseases, and the hands-on approaches necessary to acquire and interpret optimal echocardiographic images in the clinical setting.


Table of Contents

Section Title Page Action Price
Front Cover Cover
IFC ES1
Essential Echocardiography i
ESSENTIAL ECHOCARDIOGRAPHY: A Companion to Braunwald’s Heart Disease iii
Copyright iv
Dedication v
Contributors vii
Preface xi
Contents xiii
Video Contents xv
Braunwald’s Heart Disease Family of Books xxiii
I - PHYSICAL PRINCIPLES OF ULTRASOUND AND GENERATION OF IMAGES 1
1 - Physical Principles of Ultrasound and Generation of Images 1
INTRODUCTION 1
GENERATION OF IMAGES BY ULTRASOUND 1
Resolution of Echocardiographic Images 2
Phased Array and Matrix Array Transducers 4
Second Harmonic Imaging 4
PRINCIPLES OF DOPPLER IMAGING 4
Continuous Wave Doppler 6
Pulsed Wave Doppler 6
Color Flow Doppler 8
Doppler Tissue Imaging 14
2D Speckle Tracking Echocardiography 15
Suggested Readings 15
References 15.e1
2 - M-Mode Imaging 16
NORMAL M-MODE MEASUREMENTS 16
Normal M-Mode Examination of the Aortic Root, Aortic Cusp Separation, and Left Atrial Dimension 16
M-MODE ECHOCARDIOGRAPHY IN THE IDENTIFICATION OF ABNORMAL CARDIAC STRUCTURE AND FUNCTION 17
Bicuspid Aortic Valve 17
Subaortic Membrane 17
Mitral Valve Prolapse 17
Systolic Anterior Motion of the Mitral Valve 17
Valvular Vegetations 18
Rheumatic Mitral Valve Deformity 18
Left Ventricular Dyssynchrony 22
Constrictive Pericarditis 22
Cor Pulmonale 22
Severe Pulmonary Hypertension 23
Ebstein Anomaly 23
Increased Right Atrial Pressure 23
M-Mode Examination of Prosthetic Valves 23
Color M-Mode Echocardiography 24
SUMMARY 26
Suggested Readings 26
3 - Principles of Contrast Echocardiography 27
INTRODUCTION 27
MICROBUBBLE CONTRAST AGENTS 27
MICROVASCULAR BEHAVIOR OF MICROBUBBLES 29
Detection of Microbubble Ultrasound Signal 30
Contrast-Specific Imaging Methods 31
SAFETY OF MICROBUBBLE CONTRAST AGENTS 32
Suggested Readings 33
References 33.e1
4 - Principles of Transesophageal Echocardiography 34
INTRODUCTION 34
INDICATIONS 34
COMPLICATIONS 34
PATIENT MANAGEMENT 36
THE COMPREHENSIVE TEE EXAM 37
MID- AND UPPER-ESOPHAGEAL IMAGING 39
TRANSGASTRIC IMAGING 40
THORACIC AORTA 42
INTERVENTIONAL ECHOCARDIOGRAPHY 42
CONCLUSION 42
Suggested Reading 42
References 42.e1
5 - Principles of Three-Dimensional Ultrasound 43
INTRODUCTION 43
Fully Sampled Matrix Array Transducers 43
PHYSICS OF THREE-DIMENSIONAL ULTRASOUND 43
Multibeat ECG-Gated Acquisition 43
Real-Time Zoom Acquisition 44
Parallel Receive Beamforming 44
DISPLAY OF THREE-DIMENSIONAL ECHOCARDIOGRAPHIC IMAGES 45
Volume Rendering 45
Surface Rendering 46
Wireframe Rendering 46
CLINICAL APPLICATIONS OF THREE-DIMENSIONAL ECHOCARDIOGRAPHY 46
Quantification of Cardiac Chambers 46
CLINICAL APPLICATIONS OF THREE-DIMENSIONAL ECHOCARDIOGRAPHY 47
Left Ventricular Structure and Function 47
Right Ventricular Structure and Function 48
Left and Right Atria 49
Valvular Heart Disease 50
Mitral Valve 50
Aortic Valve 51
Tricuspid Valve 52
Prosthetic Valves 53
CONCLUSION 53
Suggested Reading 54
References 54.e1
6 - Principles and Practical Aspects of Strain Echocardiography 55
INTRODUCTION 55
PRINCIPLES OF STRAIN IMAGING 55
TWIST AND TORSION 55
REGIONAL AND GLOBAL FUNCTION 55
Left Ventricle 55
Right Ventricle 56
Left Atrium 56
CORONARY ARTERY DISEASE AND ISCHEMIC CARDIOMYOPATHY 57
NONISCHEMIC CARDIOMYOPATHY 57
Hypertrophic Cardiomyopathy 60
Chemotherapy-Related Cardiotoxicity 60
Other Cardiomyopathies 60
DILATED CARDIOMYOPATHY AND DYSSYNCHRONY ANALYSIS 62
VALVULAR HEART DISEASE 62
INFILTRATIVE DISEASE 62
Amyloidosis 62
Suggested Readings 63
References 63.e1
7 - Understanding Imaging Artifacts 64
INTRODUCTION 64
B-MODE ARTIFACTS 64
Shadowing (Attenuation) and Dropout Artifacts 64
Reverberation Artifacts 64
Multiple Reflection Artifacts 65
Side Lobe Artifacts 67
Refraction Artifacts 68
Beam-Width Artifacts/Partial Volume Artifacts 71
(COLOR) DOPPLER MIRROR IMAGE ARTIFACTS 71
FOUR-DIMENSIONAL ECHOCARDIOGRAPHY STITCH ARTIFACTS 72
Suggested Readings 72
References 72.e1
II - The Echocardiographic Examination 73
8 - Principles of Transthoracic Imaging Acquisition: The Standard Adult Transthoracic Echocardiographic Examination 73
INTRODUCTION 73
Transducer Positions 73
Cardiac Imaging Plane 73
Region or Structure of Interest 73
IMAGE ORIENTATION STANDARDS 77
TWO-DIMENSIONAL ECHOCARDIOGRAPHY: TOMOGRAPHIC SCAN PLANE ORIENTATION AND DISPLAY PROTOCOL 77
COMPLEMENTARY PROTOCOLS: DOPPLER, THREE-DIMENSIONAL ECHOCARDIOGRAPHY, AND MYOCARDIAL SEGMENTATION 77
Suggested Reading 95
References 95.e1
9 - The Transthoracic Examination, View by View 96
INTRODUCTION 96
LEFT PARASTERNAL VIEWS 96
APICAL VIEWS 96
SUBCOSTAL VIEWS 96
SUPRASTERNAL NOTCH VIEWS 96
Suggested Reading 108
References 108.e1
10 - Three-Dimensional Echocardiography: Image Acquisition 109
INTRODUCTION 109
THE THREE-DIMENSIONAL TRANSTHORACIC ECHOCARDIOGRAPHY DATA ACQUISITION PROTOCOL 109
TWO-DIMENSIONAL IMAGE OPTIMIZATION 110
ACQUISITION MODES 110
CROPPING AND RENDERING 112
IMAGE DISPLAY AND ANALYSIS 112
CHALLENGES AND OPTIMIZATION IN THREE-DIMENSIONAL DATA ACQUISITION 112
ELECTROCARDIOGRAPHY GATING AND BREATH HOLD 112
THREE-DIMENSIONAL GAIN OPTIMIZATION 114
LIVE THREE-DIMENSIONAL OPTIMIZATION 114
Suggested Reading 118
11 - Optimization of the Patient and Equipment 119
INTRODUCTION 119
OPTIMIZING PATIENT AND TRANSDUCER POSITIONS 119
OPTIMIZING TWO-DIMENSIONAL IMAGING: MACHINE SETTINGS 120
USE OF CONTRAST 121
OPTIMIZING THE SPECTRAL DOPPLER EXAMINATION 121
OPTIMIZING THE COLOR FLOW DOPPLER EXAMINATION 122
SUMMARY 122
Suggested Reading 129
12 - Utilizing Contrast Echocardiography in Practice 130
INTRODUCTION 130
LEFT VENTRICULAR OPACIFICATION 131
Endocardial Enhancement 131
Stress Echocardiography 132
Left Ventricular Opacification for Masses and Miscellaneous Left Ventricular Abnormalities 133
CONTRAST ECHOCARDIOGRAPHY FOR DOPPLER SPECTRAL ENHANCEMENT 134
SAFETY OF MICROBUBBLE CONTRAST AGENTS 134
General Recommendations for the Use of Contrast 134
MYOCARDIAL CONTRAST ECHOCARDIOGRAPHY 134
General Considerations 134
Assessment of Myocardial Blood Volume 135
Quantification of Myocardial Blood Flow 135
Myocardial Viability 135
SUMMARY 139
Suggested Readings 139
References 139.e1
13 - Echo On-Call: Echocardiographic Emergencies 140
INTRODUCTION 140
CARDIOVASCULAR EMERGENCIES 140
Acute Mitral Regurgitation (Flail Leaflet) 140
Ventricular Septal Defect 141
Pseudoaneurysm 141
Free Wall Rupture 142
Nonmechanical Causes of Cardiogenic Shock 143
Tamponade 143
Aortic Dissection 146
Pulmonary Embolus 147
CODES AND SHOCK: WHERE DOES STAT ECHOCARDIOGRAPHY FIT IN? 148
TRAUMA 149
Blunt Trauma 149
Penetrating Trauma 152
Suggested Reading 152
References 152.e1
III - Assessment of Cardiac Structureand Function 153
14 - Assessment of Left Ventricular Systolic Function 153
INTRODUCTION 153
LEFT VENTRICULAR SYSTOLE: CARDIAC CYCLE AND HEMODYNAMICS 155
Measurements of the Left Ventricle 155
Left Ventricular Structure: Size and Mass 155
Assessment of Cardiac Function 159
GLOBAL MEASURES OF LEFT VENTRICULAR SYSTOLIC FUNCTION 164
Myocardial Strain Imaging 164
REGIONAL MEASURES OF LEFT VENTRICULAR SYSTOLIC FUNCTION 169
Suggested Reading 170
15 - Left Ventricular Diastolic Function 171
INTRODUCTION 171
WHAT IS DIASTOLIC FUNCTION AND DYSFUNCTION? 171
Transmitral Doppler: E Wave Peak Velocity, A Wave Peak Velocity, and E/A Ratio 171
Tissue Doppler Imaging e′ 172
E/e′ Ratio 173
Left Atrial Size 173
Color M-Mode Propagation Velocity 173
Pulmonary Venous Flow 174
Tricuspid Regurgitation Velocity 175
Grading Diastolic Function 175
Estimation of Left Ventricle Filling Pressures in Specific Patient Populations 177
Atrial Fibrillation 177
AV Block and Pacing 177
Valvular Disease 177
DIASTOLIC STRESS TESTING IN PATIENTS WITH NORMAL DIASTOLIC FUNCTION AT REST: IS THERE A ROLE? 177
CONCLUSION 177
Suggested Readings 179
References 179.e1
16 - Assessment of Right Ventricular Structure and Function 180
INTRODUCTION 180
CLINICAL ASSESSMENT OF RIGHT VENTRICULAR ANATOMY AND FUNCTION 180
SUMMARY 189
Suggested Reading 189
References 189.e1
17 - Assessment of the Atria 190
INTRODUCTION 190
Left Atrium 190
Structure 190
Function 190
Right Atrium 192
The Interatrial Septum and Congenital Abnormalities of the Atria 192
Atrial Masses 193
Suggested Reading 194
References 194.e1
IV - Echocardiography for Diseases of theMyocardium 195
18 - Acute Myocardial Infarction 195
INTRODUCTION 195
ESTABLISHING THE DIAGNOSIS, EXTENT, AND LOCATION OF MYOCARDIAL INFARCTION 195
Patterns of Myocardial Infarction By Coronary Artery Territory 196
Anterior Myocardial Infarcts (Left Anterior Descending Territory) 196
Inferior Myocardial Infarcts 196
Urgent Consequences of Acute Myocardial Infarction 198
Limitations to Echocardiography In the Acute Setting 199
Suggested Reading 199
References 199.e1
19 - Mechanical Complications of Myocardial Infarction 200
INTRODUCTION 200
ACUTE MITRAL REGURGITATION 200
VENTRICULAR SEPTAL DEFECT 200
PSEUDOANEURYSM 201
FREE WALL RUPTURE 201
TAMPONADE 202
OTHER CAUSES OF CARDIOGENIC SHOCK AFTER MYOCARDIAL INFARCTION 202
Suggested Reading 203
References 203.e1
20 - Long-Term Consequences and Prognosis After Myocardial Infarction 204
INTRODUCTION 204
LEFT VENTRICULAR SCAR AND ANEURYSM 204
LEFT VENTRICULAR THROMBUS 205
LEFT VENTRICULAR REMODELING (ISCHEMIC CARDIOMYOPATHY) 205
FUNCTIONAL (SECONDARY) MITRAL REGURGITATION 206
RARE COMPLICATIONS OF MYOCARDIAL INFARCTION 207
PROGNOSIS AFTER MYOCARDIAL INFARCTION 207
Suggested Reading 208
References 208.e1
21 - Echocardiography in Heart Failure 209
ASSESSMENT OF CARDIAC STRUCTURE AND FUNCTION 209
Assessment of Ejection Fraction 209
Determination of Heart Failure Etiology 209
ASSESSMENT OF VALVULAR FUNCTION IN HEART FAILURE 211
MITRAL REGURGITATION IN HEART FAILURE 212
DOPPLER ASSESSMENT IN PATIENTS WITH HEART FAILURE 212
ASSESSMENT OF LEFT ATRIAL AND RIGHT VENTRICULAR FUNCTION 212
ASSESSMENT OF VENTRICULAR SYNCHRONY 213
DEFORMATION IMAGING IN HEART FAILURE 213
ASSESSMENT AFTER ORTHOTOPIC HEART TRANSPLANT 214
ASSESSMENT OF VENTRICULAR ASSIST DEVICES 214
ECHOCARDIOGRAPHY IN THE CONTEXT OF OTHER DIAGNOSTIC MEASURES IN HEART FAILURE 215
LUNG ULTRASOUND IN HEART FAILURE 216
Utility of Lung Ultrasound in Heart Failure 217
Limitations of Lung Ultrasound 217
Assessment of Pleural Effusions 217
Suggested Reading 218
References 218.e1
22 - Dilated Cardiomyopathies 219
INTRODUCTION 219
COMMON FEATURES OF DILATED CARDIOMYOPATHIES 219
Left Ventricular Dilation and Systolic Functional Impairment 219
Elevation of Left Ventricular Filling Pressures 221
Left Atrial Dilation 222
Right Heart Dilation and Functional Impairment 222
Functional Mitral Regurgitation 223
ARRHYTHMOGENIC CARDIOMYOPATHY 223
LEFT VENTRICULAR NONCOMPACTION 224
TACHYCARDIA-INDUCED CARDIOMYOPATHY 226
PERIPARTUM CARDIOMYOPATHY 226
TAKOTSUBO CARDIOMYOPATHY 226
ALCOHOLIC CARDIOMYOPATHY 227
CARDIOMYOPATHY IN CHAGAS DISEASE 228
CHEMOTHERAPY-INDUCED CARDIOMYOPATHY 229
Suggested Reading 229
References 229.e1
23 - Hypertrophic Cardiomyopathy 230
INTRODUCTION 230
SARCOMERE GENE MUTATIONS CAUSE HYPERTROPHIC CARDIOMYOPATHY 231
CARDIAC MORPHOLOGY 231
LEFT VENTRICULAR SYSTOLIC AND DIASTOLIC FUNCTION 235
DEVELOPMENT OF HYPERTROPHIC CARDIOMYOPATHY 237
LEFT VENTRICULAR OUTFLOW OBSTRUCTION AND MITRAL VALVE ABNORMALITIES 237
TREATMENT OF HYPERTROPHIC CARDIOMYOPATHY 239
USING ECHOCARDIOGRAPHY IN THE DIFFERENTIAL DIAGNOSIS OF HYPERTROPHIC CARDIOMYOPATHY 242
Athlete’s Heart 242
Focal Upper Septal Hypertrophy 242
Infiltrative and Metabolic Cardiomyopathies 242
CONCLUSION 244
Suggested Reading 244
References 244.e1
24 - Restrictive and Infiltrative Cardiomyopathies 245
INTRODUCTION 245
SPECTRUM OF RESTRICTIVE CARDIOMYOPATHY 245
Diagnosis of Restrictive Cardiomyopathy 245
ECHOCARDIOGRAPHY IN RESTRICTIVE CARDIOMYOPATHY 245
Doppler Features 245
CARDIAC AMYLOIDOSIS 247
MITOCHONDRIAL CARDIOMYOPATHY 248
ENDOMYOCARDIAL FIBROSIS AND LÖFFLER (EOSINOPHILIC) ENDOCARDITIS 248
IDIOPATHIC RESTRICTIVE CARDIOMYOPATHY 250
MUCOPOLYSACCHARIDOSES 250
ANDERSON-FABRY DISEASE 251
GLYCOGEN STORAGE DISEASES 252
IRON OVERLOAD CARDIOMYOPATHY 253
CARCINOID SYNDROME 253
POSTRADIATION THERAPY AND CHEMOTHERAPY-RELATED CARDIAC DYSFUNCTION 254
SYSTEMIC SCLEROSIS 254
PSEUDOXANTHOMA ELASTICUM 254
Suggested Reading 255
References 255.e1
25 - Echocardiography in Assessment of Cardiac Synchrony 256
INTRODUCTION 256
ECHOCARDIOGRAPHIC METHODS TO ASSESS DYSSYNCHRONY 256
NEW UNDERSTANDING OF MECHANICAL DYSSYNCHRONY 258
MYOCARDIAL SUBSTRATES OF SYNCHRONY AND DISCOORDINATION 259
LACK OF SYNCHRONY AND RISK FOR VENTRICULAR ARRHYTHMIAS 260
DYSSYNCHRONY ASSOCIATED WITH RIGHT VENTRICULAR PACING 261
FUTURE APPLICATIONS OF ECHOCARDIOGRAPHIC SYNCHRONY 262
Suggested Reading 263
References 263.e1
26 - Echocardiography in Assessment of Ventricular Assist Devices 264
INTRODUCTION 264
TYPES OF VENTRICULAR ASSIST DEVICES 264
Short-Term Ventricular Assist Devices 264
PLANNING FOR A LEFT VENTRICULAR ASSIST DEVICE 264
Left Ventricular Structure and Function 264
Right Ventricular Structure and Function 264
Valves 265
Endocarditis 266
Aorta 266
Congenital Heart Disease 266
INTRAOPERATIVE 266
Preimplantation 266
POSTIMPLANT 267
CONCLUSIONS 269
Suggested Reading 269
References 269.e1
27 - Stress Echocardiography and Echo in Cardiopulmonary Testing 270
INTRODUCTION 270
Ischemic Cascade 270
Stress Protocols 270
Exercise Protocols 270
Pharmacologic Stress Protocols 270
Assessment of Ischemia 270
Image Interpretation 270
UTILITY OF EXERCISE ECHOCARDIOGRAPHY BEYOND ISCHEMIA 273
Valvular Disease 273
Left Ventricle Function 274
Exercise-Induced Pulmonary Hypertension 274
Clinical Significance 274
Low-Flow, Low-Gradient Aortic Stenosis With Preserved Left Ventricle Ejection Fraction 274
Aortic Regurgitation 275
V - Valvular Heart Disease 279
28 - Mitral Valve Disease 279
INTRODUCTION 279
MITRAL VALVE ANATOMY 279
ECHOCARDIOGRAPHIC VIEWS OF THE MITRAL VALVE 279
Transthoracic Echocardiography 279
MITRAL REGURGITATION 281
Primary Mitral Regurgitation 283
Secondary Mitral Regurgitation 285
MITRAL STENOSIS 288
Rheumatic Mitral Stenosis 289
Calcific Mitral Stenosis 290
Radiation-Associated Mitral Valve Disease 290
CONGENITAL MITRAL VALVE DISORDERS 291
Mitral Valve Cleft 291
Mitral Valve Parachute 291
Mitral Arcade 291
Supravalvular Mitral Ring 293
CONCLUSION 293
Suggested Reading 293
References 293.e1
29 - Aortic Valve Disease 294
INTRODUCTION 294
NORMAL AORTIC VALVE ANATOMY AND COMMON CONGENITAL ANOMALIES 295
VALVULAR AORTIC STENOSIS 296
Quantitation of Aortic Stenosis Severity 296
Additional Measures of Aortic Stenosis Severity 298
Body Surface Area Correction for Aortic Valve Area 299
Low Gradient Severe Aortic Stenosis 299
SUBVALVULAR OR SUPRAVALVULAR AORTIC STENOSIS 299
AORTIC REGURGITATION 299
Suggested Reading 303
References 303.e1
30 - Tricuspid and Pulmonic Valve Disease 304
INTRODUCTION 304
NORMAL TRICUSPID VALVE ANATOMY 304
TWO-DIMENSIONAL ECHO VIEWS FOR ASSESSING THE TRICUSPID VALVE 304
THREE-DIMENSIONAL ECHO OF THE TRICUSPID VALVE 306
ABNORMALITIES OF THE TRICUSPID VALVE 308
Carcinoid Valve Disease 308
Rheumatic Valve Disease 308
Tricuspid Valve Endocarditis 308
Flail Tricuspid Leaflet 309
Functional Tricuspid Regurgitation 309
Ebstein Anomaly of the Tricuspid Valve 309
Tricuspid Atresia 309
ECHO DOPPLER ASSESSMENT OF TRICUSPID REGURGITATION SEVERITY 309
ROLE OF ECHOCARDIOGRAPHY IN PERCUTANEOUS TRICUSPID VALVE REPLACEMENT 310
ABNORMALITIES OF THE PULMONIC VALVE 310
THREE-DIMENSIONAL ECHO OF THE PULMONIC VALVE 311
PULMONIC VALVE ENDOCARDITIS 312
CONGENITAL VALVULAR PULMONIC STENOSIS 312
PULMONIC STENOSIS S/P VALVULOPLASTY 313
CARCINOID INVOLVEMENT OF THE PULMONIC VALVE 313
ECHO DOPPLER ASSESSMENT OF PULMONIC REGURGITATION SEVERITY 314
SUMMARY 314
Suggested Reading 314
References 314.e1
31 - Prosthetic Valves 315
INTRODUCTION 315
NORMAL APPEARANCE AND FUNCTION 315
PROSTHETIC VALVE STENOSIS 316
Gradients 317
Pressure Recovery 317
Patient-Prosthesis Mismatch 318
Causes of Prosthetic Valve Stenosis 319
PROSTHETIC VALVE REGURGITATION 320
PROSTHETIC VALVE ENDOCARDITIS 320
Suggested Reading 322
References 322.e1
32 - Echocardiography in Percutaneous Valvular Intervention 323
INTRODUCTION 323
TRANSCATHETER AORTIC VALVE REPLACEMENT 323
Preimplantation Assessment 323
INTRAPROCEDURAL IMAGING 325
Wire and Cannulation Position 326
Balloon Aortic Valvuloplasty 330
Ventricular and Baseline Valvular Function 330
Transcatheter Valve Positioning 330
POSTIMPLANTATION ASSESSMENT 330
Paravalvular Regurgitation 330
TRANSCATHETER MITRAL VALVE REPAIR 333
PREPROCEDURAL IMAGING 334
INTRAPROCEDURAL GUIDANCE 335
Transseptal Puncture 336
Positioning and Orienting the MitraClip 338
Grasping the Mitral Leaflets 339
Prerelease Assessment 339
Post-MitraClip Assessment 339
OTHER TRANSCATHETER MITRAL VALVE REPAIR DEVICES AND TRANSCATHETER MITRAL VALVE REPLACEMENT 340
TRICUSPID REPAIR DEVICES 341
ECHOCARDIOGRAPHY IN TRANSCATHETER VALVE-IN-SURGICAL-VALVE PROCEDURES 342
INTRAPROCEDURAL IMAGING 342
PROCEDURAL APPROACH 343
INTRAPROCEDURAL IMAGING 344
CONCLUSION 345
Suggested Reading 345
References 346.e1
VI - Diseases of the Pericardium and Great Vessels 347
33 - Pericardial Disease 347
INTRODUCTION 347
PERICARDIAL FLUID 347
Fluid Characteristics 347
Effusion Size 347
Distinguishing Features 347
ACUTE PERICARDITIS 347
RECURRENT PERICARDITIS 348
PERICARDIAL TAMPONADE 348
PERICARDIAL CONSTRICTION 349
OTHER PERICARDIAL DISORDERS AND ABNORMALITIES 352
Congenital Absence of Pericardium 352
Pericardial Cysts 352
Pericardial Involvement in Malignancy 352
MULTIMODALITY IMAGING 352
CONCLUSION 353
Suggested Reading 353
References 353.e1
34 - Diseases of the Aorta 354
INTRODUCTION 354
ANATOMY, NOMENCLATURE, AND DIMENSIONS 354
Aortic Measurements and Dimensions 354
ECHOCARDIOGRAPHIC VIEWS 354
Transthoracic Echocardiography 354
Transesophageal Echocardiography 355
Doppler Flows in the Aorta 356
AORTIC ANEURYSMS 356
Sinus of Valsalva Aneurysms 358
Associated Abnormalities 358
Surveillance of Thoracic Aortic Aneurysms 358
AORTIC DISRUPTIONS (ACUTE AORTIC SYNDROMES) 359
PERIOPERATIVE AND POSTOPERATIVE IMAGING 361
Postoperative Imaging 365
INTRALUMINAL PATHOLOGY 366
Atheroma 366
Aortic Thrombus 366
Aortic Tumors 366
COARCTATION OF THE AORTA 366
Suggested Reading 368
References 368.e1
VII - Diseases of the Pulmonary Artery and Veins 369
35 - Pulmonary Embolism 369
INTRODUCTION 369
UTILITY OF ECHOCARDIOGRAPHY IN PULMONARY EMBOLISM 369
Identification of Thrombus by Echocardiography 369
Assessment of the Right Ventricle in Pulmonary Embolism 369
Regional Right Ventricular Dysfunction: The “Mcconnell” Sign 370
The Influence of Elevated Pulmonary Pressures on Echocardiographic Features in Pulmonary Embolism 371
ECHOCARDIOGRAPHY IN PROGNOSIS AND MANAGEMENT OF PULMONARY EMBOLISM 371
Echocardiography in Assessment of Response to Therapy in Pulmonary Embolism 372
Novel Methods to Assess Right Ventricular Function in Pulmonary Embolism 372
Transesophageal Echocardiography in Pulmonary Embolism 372
DISTINGUISHING PULMONARY EMBOLISM FROM PULMONARY HYPERTENSION 374
Suggested Reading 375
36 - Pulmonary Hypertension 376
INTRODUCTION 376
ASSESSMENT OF RIGHT VENTRICLE AFTERLOAD/PULMONARY VASCULAR FUNCTION 376
Pulmonary Artery Systolic Pressure 376
Diastolic Pulmonary Artery Pressure 376
Mean Pulmonary Artery Pressure 376
The Right Atrium and Right Atrial Pressure 376
OTHER MEASURES OF RIGHT VENTRICLE AFTERLOAD 376
Pulmonary Arterial Acceleration Time 376
RIGHT VENTRICULAR STRUCTURE AND FUNCTION 379
Right Ventricular Wall Thickness 379
Tricuspid Annular Plane Systolic Excursion 379
Right Ventricular Area Assessment 380
Three-Dimensional Volume Assessment 380
Doppler Tissue Imagings’ cm/s 380
Iso-Volumetric Acceleration 381
Right Ventricular E/e′ 381
Strain/Strain Rate 381
TIMING MEASUREMENTS 381
Right Ventricular Isovolumetric Relaxation Time Measurement 381
Myocardial Performance Index or Tei Index 382
Right Ventricular Assessment During Exercise 383
Suggested Reading 384
References 384.e1
VIII - Cardiac Masses 385
37 - Primary and Secondary Tumors 385
INTRODUCTION 385
TUMOR TYPES 385
Primary Versus Secondary Tumors 385
Primary Benign Tumors 385
Myxoma 385
Lipoma 385
Papillary Fibroelastoma 386
Benign Versus Malignant 388
Primary Malignant Tumors 388
Secondary Tumors 389
TUMOR LOCATIONS: SITE-SPECIFIC DIFFERENTIAL 389
Atrial Tumors 389
Ventricular Tumors 389
Valvular Tumors 389
Pericardial Tumors 390
CLINICAL PRESENTATION OF TUMORS 390
Suggested Reading 391
References 391.e1
38 - Identification of Intracardiac Thrombus 392
INTRODUCTION 392
INTRACARDIAC SOURCES OF EMBOLI 392
Left Ventricle 392
Left Atrium 392
Right Ventricle/Right Atrium 392
Prosthetic Valves 392
Interatrial and Interventricular Septum 393
Nonthrombotic Causes of Embolism 394
PREVALENCE OF AND RISK FACTORS FOR LEFT VENTRICULAR AND ATRIAL THROMBI 394
ECHOCARDIOGRAPHIC APPEARANCE 395
RISK FACTORS FOR EMBOLIZATION 397
CHOICE OF INITIAL TEST 397
ROLE OF FOLLOW-UP IMAGING 397
PREVENTION OF THROMBOEMBOLISM 397
CONCLUSIONS 398
Suggested Reading 398
References 398.e1
39 - Other Cardiac Masses 399
INTRODUCTION 399
VARIANTS OF NORMAL STRUCTURE 399
DEGENERATIVE/ACQUIRED MASSES 400
POSTSURGICAL MASSES 401
EXTRACARDIAC STRUCTURES 402
ULTRASOUND ARTIFACTS 402
Suggested Reading 403
References 404.e1
IX - Systemic Diseases Involving the Heart 405
40 - Echocardiography in Infective Endocarditis 405
INTRODUCTION 405
DIAGNOSIS 405
Indications for Transthoracic Echocardiography and Transesophageal Echocardiography 405
VEGETATIONS 408
COMPLICATIONS OF ENDOCARDITIS 410
Abscess, Pseudoaneurysm, and Fistula 410
RIGHT-SIDED ENDOCARDITIS 411
NONVALVULAR ENDOCARDITIS 411
Device-Related Infective Endocarditis 411
Infection of Cardiac Shunts 412
PURULENT PERICARDITIS 412
ECHOCARDIOGRAPHIC PREDICTORS OF OUTCOMES 412
Embolism 412
Overall Prognosis 412
SURGERY FOR ENDOCARDITIS 412
Echocardiographic Indicators for Surgery 412
Frequency of Echocardiography 413
Role of 3D Echocardiography 413
Suggested Reading 415
References 415.e1
41 - Other Systemic Diseases and the Heart 416
INTRODUCTION 416
SARCOIDOSIS 416
HYPEREOSINOPHILIC SYNDROME (LOEFFLER ENDOCARDITIS) 416
THYROID DISEASE 417
CARCINOID HEART DISEASE (SEE ALSO CHAPTER 30) 418
HEMOCHROMATOSIS 418
MUSCULAR DYSTROPHIES 419
LYSOSOMAL STORAGE DISEASES 419
Glycogen Storage Diseases 419
Fabry Disease 419
Mucopolysaccharidoses 419
Sphingolipidoses 419
CONNECTIVE TISSUE DISORDERS 420
Ehlers-Danlos Syndrome 420
Marfan Syndrome 420
MARANTIC ENDOCARDITIS 420
DIABETES, HYPERTENSION, AND OBESITY 421
Suggested Reading 421
References 421.e1
42 - Echocardiography in Malignant Disease 422
INTRODUCTION 422
BASELINE ASSESSMENT PRIOR TO INITIATION OF CANCER TREATMENTS 422
DURING CANCER TREATMENT 422
Contrast Echocardiography 422
Three-Dimensional Echocardiography 423
Other Imaging Modalities 423
Left Ventricular Ejection Fraction Surveillance Schedules 423
Anthracyclines 423
Trastuzumab 423
Left Ventricular Diastolic Function 423
Other 424
Right Ventricular Function 424
Valvular Assessment 424
Pericardial Disease 425
Pulmonary Arterial Hypertension 425
Cardiac Masses 426
Stress Echocardiography 426
AFTER TREATMENT: SURVIVORSHIP 426
Survivors of Thoracic Radiation Therapy 426
Survivors of Childhood Malignancies 426
FUTURE DIRECTIONS 426
CONCLUSION 427
Suggested Reading 427
References 428.e1
X - Congenital Heart Disease in the Adult 429
43 - Atrial Septal Defect 429
INTRODUCTION 429
ANATOMY/EMBRYOLOGY 429
PATENT FORAMEN OVALE 429
CLINICAL PRESENTATION OF ATRIAL LEVEL DEFECTS 429
ATRIAL SEPTAL DEFECTS 429
VENOUS SEPTATION DEFECTS 430
IMAGING APPROACH 430
ATRIAL LEVEL SHUNTING CLOSURE 430
IMAGING DURING PERCUTANEOUS CLOSURE 430
ADDITIONAL TECHNIQUES AND PITFALLS 432
Clues To Undiagnosed Atrial Level Shunting 432
Common Mistakes in Diagnosis 432
Suggested Reading 434
References 434.e1
44 - Ventricular Septal Defect 435
INTRODUCTION 435
ADULT PRESENTATION 435
TYPES/LOCATIONS OF VENTRICULAR SEPTAL DEFECTS 435
Perimembranous Ventricular Septal Defects 435
Muscular/Trabecular Ventricular Septal Defects 435
Outlet Ventricular Septal Defects 435
Inlet Ventricular Septal Defects 435
Diagnostic Clues to Inlet Ventricular Septal Defect or Atrioventricular Septal Defect 435
BASIC IMAGING APPROACH TO VENTRICULAR SEPTAL DEFECTS 437
UNIQUE VENTRICULAR SEPTAL DEFECT PHYSIOLOGY 438
Double-Chambered Right Ventricle 438
Eisenmenger Syndrome 438
Suggested Reading 439
References 439.e1
45 - Other Common Congenital Defects in Adults 440
INTRODUCTION 440
SEGMENTAL ANATOMY 440
PATENT DUCTUS ARTERIOSUS 440
TETRALOGY OF FALLOT 440
Imaging Approach to the Adult With Repaired Tetralogy of Fallot 440
Key Imaging Views 441
TRANSPOSITION OF THE GREAT ARTERIES 441
COARCTATION 443
FONTAN 444
EBSTEIN ANOMALY 445
Suggested Reading 446
References 446.e1
XI - Miscellaneous Topics in Echocardiography 447
46 - Handheld Echocardiography 447
INTRODUCTION 447
CURRENT HANDHELD DEVICES 447
THE LEARNING CURVE 447
VALIDATION OF HANDHELD DEVICES 450
SUGGESTED PROTOCOL 450
QUANTITATIVE ASSESSMENT WITH HANDHELD ECHOCARDIOGRAPHY 451
SPECIFIC ROLES FOR HANDHELD ECHOCARDIOGRAPHY 454
HANDHELD ECHOCARDIOGRAPHY AS A SCREENING TOOL 454
COST AND WORKFLOW ISSUES 455
FUTURE DEVELOPMENTS 455
Suggested Reading 455
References 455.e1
47 - Appropriate Use of Echocardiography 456
INTRODUCTION 456
DEVELOPMENT OF APPROPRIATE USE CRITERIA 456
APPLICATION OF APPROPRIATE USE CRITERIA 456
FUTURE DIRECTIONS FOR APPROPRIATE USE CRITERIA 458
Suggested Reading 459
References 459.e1
48 - Echocardiography in the Context of Other Cardiac Imaging Modalities 460
INTRODUCTION 460
CHAMBER QUANTIFICATION: VOLUMES AND FUNCTION 460
MORPHOLOGY 462
TISSUE CHARACTERIZATION 464
CORONARY DISEASE 466
CARDIAC MASSES 469
PERICARDIAL DISEASE 470
DISEASES OF THE AORTA 472
CONCLUSION 472
Suggested Reading 473
References 473.e1
49 - Transesophageal Echocardiography for Cardiac Surgery 474
INTRODUCTION 474
ROLE OF THE INTRAOPERATIVE ECHOCARDIOGRAPHER 474
IMPACT OF INTRAOPERATIVE TRANSESOPHAGEAL ECHOCARDIOGRAPHY IN CARDIAC SURGERY 474
OBJECTIVES OF THE INTRAOPERATIVE TEE EXAM 474
THE INTRAOPERATIVE TRANSESOPHAGEAL ECHOCARDIOGRAPHY EXAM 475
IMPACT OF INTRAOPERATIVE TRANSESOPHAGEAL ECHOCARDIOGRAPHY IN NONCARDIAC SURGERY 478
Suggested Reading 479
References 479.e1
A - Reference Tables 480
B - COMMONLY UTILIZED EQUATIONS IN ECHOCARDIOGRAPHY 483
GENERAL BODY MEASURES 483
Body Mass Index 483
Body Surface Area (Mosteller Formula) 483
ECHOCARDIOGRAPHY 483
Left and Right Ventricle 483
Left Ventricular Volume (Teicholz Formula) 483
Left Ventricular Ejection Fraction (Simplified Quinones Equation) 483
Left Ventricular Fractional Shortening 483
Left Ventricular Mass (Linear Method, Cube Formula) 483
Relative Wall Thickness 483
Myocardial Performance, or Tei Index (Left Ventricular) (Fig. B.1; see also Fig. 14.12) 483
Myocardial Performance, or Tei Index (Right Ventricular) 483
Left Ventricular Wall Motion Score Index (for 17 Segment Left Ventricular Model) 484
Stroke Volume 484
Cardiac Output 484
Valves, General 484
Aortic Stenosis 484
Aortic Regurgitation 485
Regurgitant Volume by the PISA method 485
Regurgitant Volume by the Continuity Equation (Volumetric Method) 485
Regurgitant Fraction by the PISA/2D Method 485
Mitral Stenosis 485
Mitral Regurgitation 485
Regurgitant Volume by PISA Method 485
Regurgitant Volume by Continuity Equation (Volumetric Method) (see Fig. 28.13) 485
Regurgitant Fraction by PISA/2D Method 485
Tricuspid Regurgitation 486
Pulmonic Regurgitation 486
Pulmonary Vascular Resistance 486
EXERCISE STRESS TESTING 486
Suggested Reading 486
Index 487
A 487
B 488
C 488
D 489
E 489
F 490
G 490
H 490
I 491
L 491
M 492
N 492
O 492
P 492
Q 493
R 493
S 494
T 495
U 496
V 496
W 496
IBC 503