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Cardiology, An Issue of Physician Assistant Clinics, E-Book

Cardiology, An Issue of Physician Assistant Clinics, E-Book

Daniel T. Thibodeau

(2017)

Additional Information

Abstract

This issue of Physician Assistant Clinics, guest edited by Daniel Thibodeau MHP, PA-C, DFAAPA, is devoted to Cardiology. Articles in this issue include: Hypertension: Evaluation, Management and Keeping Patients in the Safe Zone; Cardiovascular Risk and Assessment: Impact of Comorbidities to the Cardiovascular System; Arrhythmia Detection and Management; Anticoagulation: The Successes and Pitfalls of Long-term Management; Dyslipidemia: Long-term Management and Other Uses of Statins for Cardiac Disease; Acute Coronary Syndrome: Care After a Patient Event and Strategies to Improve Adherence; Evaluation of Chest Pain in the Primary Care Setting; Ischemic Heart Disease; Heart Failure and Cardiomyopathy; Pulmonary Hypertension and Thromboembolism: Long-term Management and Chronic Oral Anticoagulation; Approaches to Valvular Disease in the Primary Care Setting; and Syncope: Initial Evaluation and Workup in the Primary Care Office.

Table of Contents

Section Title Page Action Price
Front Cover Cover
Cardiology i
Copyright\r ii
CME Accreditation Page iii
PROGRAM OBJECTIVE iii
TARGET AUDIENCE iii
LEARNING OBJECTIVES iii
ACCREDITATION iii
DISCLOSURE OF CONFLICTS OF INTEREST iii
UNAPPROVED/OFF-LABEL USE DISCLOSURE iii
TO ENROLL iii
METHOD OF PARTICIPATION iii
CME INQUIRIES/SPECIAL NEEDS iii
Contributors v
CONSULTING EDITOR v
EDITOR v
AUTHORS v
Contents vii
Foreword: Getting Ready for Boards? vii
Preface: Cardiology vii
Hypertension: An Evidence Informed, Case Based Approach vii
Evaluation of Chest Pain in the Primary Care Setting vii
Cardiac Arrhythmias: Moving to the Beat of a Different Drummer vii
Anticoagulation: The Successes and Pitfalls of Long-Term Management viii
Acute Coronary Syndrome: Care After a Patient Event and Strategies to Improve Adherence viii
Dyslipidemia: How Low Should We Go? A Review of Current Lipid Guidelines viii
Heart Failure viii
Ischemic Heart Disease: Evaluating for Potential Disease in the Previously Undiagnosed, Those Experiencing Angina, and in T ... ix
Approaches to Valvular Heart Disease in the Primary Care Setting: Classic Presentations and Current Management Guidelines ix
Syncope: Primary Care Office Evaluation and Workup ix
Pulmonary Hypertension and Thrombembolism—Long-Term Management and Chronic Oral Anticoagulation ix
Preventative Cardiology x
PHYSICIAN ASSISTANT CLINICS\r xi
FORTHCOMING ISSUES xi
January 2018 xi
April 2018 xi
RECENT ISSUES xi
July 2017 xi
April 2017 xi
January 2017 xi
Foreword: Getting Ready for Boards?\r\r xiii
Preface:\rCardiology xv
Hypertension: An Evidence Informed, Case Based Approach 557
Key points 557
BACKGROUND 557
CASES 560
Monday 560
Tuesday 561
Wednesday 563
Thursday 564
SUMMARY 567
REFERENCES 568
Evaluation of Chest Pain in the Primary Care Setting 571
Key points 571
INTRODUCTION 571
STATISTICS AND DEMOGRAPHICS 571
CASE EXAMPLE 1 572
HISTORY 573
RISK FACTORS 574
Coronary Artery Calcium Imaging 575
CASE EXAMPLE 2 575
PHYSICAL EXAMINATION 575
DIFFERENTIAL DIAGNOSIS 576
CASE EXAMPLE 3 576
CLINICAL WORK-UP 576
LABORATORY STUDIES 578
Complete Blood Count 578
Comprehensive Metabolic Profile 578
Troponin 578
Brain Natriuretic Peptide 579
Other Blood Testing 580
ANCILLARY TESTING 580
Electrocardiogram 580
Chest Radiograph 580
Echocardiogram 581
NONINVASIVE TESTING 581
Can the Patient Perform the Test Being Ordered? 582
Does the Patient Have Evidence of Abnormal Changes to the Electrocardiogram? 582
Does the Patient Need an Assessment of Myocardial Viability or Evidence of Disease? 582
Regular Treadmill Stress Test 583
Nuclear Stress Testing 584
Pharmacologic 584
Stress Radionuclide Myocardial Perfusion Imaging 584
Vasodilator 584
Inotrope or Chronotropic 584
Stress Echocardiography 585
Stress MRI 585
Sensitivity and Specificity of Testing 585
INVASIVE TESTING 587
Cardiac Catheterization 587
TREATMENT CONSIDERATIONS 587
SUMMARY 587
REFERENCES 587
Cardiac Arrhythmias 589
Key points 589
INTRODUCTION 589
ATRIAL FIBRILLATION 589
Risk Factors 590
What is Atrial Fibrillation? 590
Symptoms 591
Treatment 591
Rate Control Strategies 592
Rhythm Control 593
Anticoagulation 594
ATRIAL FLUTTER 595
ATRIOVENTRICULAR BLOCK 596
SICK SINUS SYNDROME 597
LONG QT SYNDROME 597
WOLFF-PARKINSON-WHITE SYNDROME 598
SINUS ARRHYTHMIA 599
REFERENCES 599
Anticoagulation: The Successes and Pitfalls of Long-Term Management 603
Key points 603
INTRODUCTION 603
ANTICOAGULATION MEDICATIONS 604
VITAMIN K ANTAGONISTS 604
DIRECT ORAL ANTICOAGULATION 605
DIRECT THROMBIN INHIBITOR 605
Dabigatran Etexilate Mesylate 605
FACTOR XA INHIBITORS 605
Rivaroxaban 605
Apixaban 607
Edoxaban 607
Reversal Agents 607
What Direct Oral Anticoagulant Should I Choose for My Patient? 608
Anticoagulation: Indications and Duration of Therapies 611
Venous Thromboembolism/Pulmonary Embolism 612
Atrial Fibrillation/Atrial Flutter 613
Prevention of Deep Vein Thrombosis/Pulmonary Embolism Following Joint Surgery 613
Discontinuation 613
SUMMARY 614
REFERENCES 614
Acute Coronary Syndrome 623
Key points 623
MEDICATION THERAPY IN THE POST–MYOCARDIAL INFARCTION OR POSTINTERVENTION PATIENT 623
FOLLOW-UP SCHEDULE IN THE POST–MYOCARDIAL INFARCTION OR POSTINTERVENTION PATIENT 625
STRATEGIES TO IMPROVE PATIENT ADHERENCE 626
POSTINTERVENTION COMPLICATIONS 628
SUMMARY 629
REFERENCES 630
Dyslipidemia 633
Key points 633
INTRODUCTION 633
LABORATORY ASSESSMENT OF HYPERLIPIDEMIA 635
DIFFERENCES BETWEEN THE GUIDELINES 636
Focus 636
Therapeutic Target 636
Risk Assessment 637
SPECIFIC PROVISIONS OF THE 2013 GUIDELINE 637
NONSTATIN DRUG THERAPY 640
LIPID MANAGEMENT IN SPECIAL POPULATIONS 642
Children and Adolescents 642
The Elderly 644
Chronic Kidney Disease 644
Comorbid Conditions Affecting Statin Therapy 645
Human Immunodeficiency Virus Patients 645
SUMMARY 646
ADDITIONAL RESOURCES 646
REFERENCES 646
Heart Failure 651
Key points 651
INTRODUCTION 651
Definition of Heart Failure 651
Clinical case 652
Epidemiology 652
Impact on Health Care System 653
Pathophysiology of Heart Failure 653
Classifications of Heart Failure 654
Systolic heart failure 654
Diastolic heart failure 654
Combined systolic and diastolic heart failure 655
Clinical case 655
Risk Factors and Comorbidities 655
The Heart Failure Continuum 655
History and Physical Examination 656
Differential Diagnosis 658
Testing and Diagnostic Studies 658
Natriuretic peptides 659
Echocardiography 659
Chest radiography 660
Electrocardiogram 660
Goals for Treatment 661
Clinical Management 661
Drug Therapies 662
Angiotensin-converting enzyme inhibitors 664
Angiotensin receptor blockers 664
β-Adrenergic receptor blockers 664
Hydralazine and nitrates 665
Diuretics 665
Angiotensin II receptor blocker/neprilysin inhibitor 665
Ivabradine 666
Lifestyle Modifications 666
Weight and fluid monitoring 666
Sodium restriction and diet 667
Blood pressure management 667
Activity and exercise 667
Additional therapies 667
End of Life and Palliative Care 667
SUMMARY 669
REFERENCES 669
Ischemic Heart Disease 671
Key points 671
NONINVASIVE STRESS TESTING MODALITIES: STRESSING METHODS 672
Exercise (Treadmill) Electrocardiogram Stress 672
Approaches to Valvular Heart Disease in the Primary Care Setting 689
Key points 689
INTRODUCTION 689
Aortic Stenosis 691
Risk factors for aortic stenosis 691
Presentation and natural history of aortic stenosis 692
Key features of the physical examination:8 692
Key features of the history:8 693
Natural history 693
Evaluation and grading of aortic stenosis 693
Treatment: surgical versus nonsurgical 693
Aortic Regurgitation 697
Risk factors for aortic regurgitation 698
Syncope: Primary Care Office Evaluation and Workup 715
Key points 715
INTRODUCTION 715
CAUSES 716
NEURAL CAUSES 716
Vasovagal 717
Carotid Sinus Sensitivity 717
Situational 717
Postexertional 717
ORTHOSTATIC CAUSES 718
Volume Deficit 718
Medications 718
Autonomic Failure 719
Shock 719
CARDIOVASCULAR CAUSES 719
Arrhythmias 720
Sinus bradycardia and heart blocks 720
Congenital long QT syndrome and secondary QT prolongation 720
Brugada syndrome 720
Other potential arrhythmia causes to consider 721
Postural orthostatic tachycardia syndrome 721
Pacemaker or automatic implantable cardioverter defibrillator 722
Structural 722
Indirect Cardiac 722
WORKUP 722
Laboratory Testing 722
Electrocardiogram and Telemetry 722
Holter Monitor 723
Event Monitor 723
Electrophysiologic Study 723
Tilt-Table Testing 723
Echocardiogram 723
Stress Test 724
Head Computed Tomography 724
DISPOSITION 724
REFERENCES 725
Pulmonary Hypertension and Thrombembolism—Long-Term Management and Chronic Oral Anticoagulation 727
Key points 727
INTRODUCTION 727
GROUP 1—PULMONARY ARTERY HYPERTENSION 728
Group 1.1—Idiopathic Pulmonary Arterial Hypertension 729
Group 1.2—Heritable Pulmonary Arterial Hypertension 730
Group 1.3—Drugs and Toxin Induced 730
Group 1.4—Associated with 730
Group 1.4.1—Connective tissue disease 730
Group 1.4.2—HIV infection 731
Group 1.4.3—Portal hypertension 731
Group 1.4.4—Congenital heart disease 731
Group 1.4.5—Schistosomiasis 731
Group 1’ 731
GROUP 1’’ 731
GROUP 2—PULMONARY HYPERTENSION DUE TO LEFT HEART DISEASE 731
GROUP 3—PULMONARY HYPERTENSION DUE TO LUNG DISEASES AND/OR HYPOXIA 731
GROUP 4—CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION 732
GROUP 5—PULMONARY HYPERTENSION WITH UNCLEAR MULTIFACTORIAL MECHANISMS 732
Symptoms 732
Evaluation and Screening 732
Treatment and Management of Pulmonary Artery Hypertension 734
Medical Therapies 734
Anticoagulation 735
REFERENCES 736
Preventative Cardiology 743
Key points 743
INTRODUCTION 743
PATHOGENESIS OF ATHEROSCLEROSIS 747
IDENTIFICATION OF RISK FACTORS 748
QUANTIFICATION AND MEASUREMENT OF CARDIOVASCULAR RISK 750
STRATEGIES FOR RISK PREVENTION 751
CONNECTING RISK ASSESSMENT AND PREVENTION STRATEGIES TO INTERVENTIONS 753
SUMMARY 755
REFERENCES 755