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Book Details
Abstract
This issue of Surgical Pathology Clinics, edited by Dr. Thomas Brenn, will discuss the latest updates in Dermatopathology. Topics covered in this issue include, but are not limited to EBV-related cutaneous lymphoproliferative disease; CD30-positive lymphoproliferative disorders of the skin; Spitz tumors; Atypical fibroxanthoma; Cutaneous malignant peripheral nerve sheath tumour; Sebaceous Neoplasms; Sweat gland tumors; and Cutaneous immunobullous disorders, among others.
Table of Contents
| Section Title | Page | Action | Price |
|---|---|---|---|
| Front Cover | Cover | ||
| Dermatopathology | i | ||
| Copyright\r | ii | ||
| Contributors | iii | ||
| CONSULTING EDITOR | iii | ||
| EDITOR | iii | ||
| AUTHORS | iii | ||
| Contents | v | ||
| Preface: Diagnostic Challenges in Dermatopathology | v | ||
| Spitz Tumors of the Skin | v | ||
| Advances in the Genetic Characterization of Cutaneous Mesenchymal Neoplasms: Implications for Tumor Classification and Nove ... | v | ||
| Atypical Fibroxanthoma Revisited | v | ||
| Cutaneous Malignant Peripheral Nerve Sheath Tumor | v | ||
| Histopathology of Spindle Cell Vascular Tumors | vi | ||
| Sebaceous Neoplasms | vi | ||
| Update on Malignant Sweat Gland Tumors | vi | ||
| Merkel Cell Carcinoma | vi | ||
| Cutaneous Lymphomas with Cytotoxic Phenotype | vii | ||
| Epstein-Barr Virus–associated Lymphoproliferative Disorders in the Skin | vii | ||
| Cutaneous Pseudolymphoma | vii | ||
| Histopathologic Spectrum of Connective Tissue Diseases Commonly Affecting the Skin | vii | ||
| Immunofluorescence of Autoimmune Bullous Diseases | viii | ||
| SURGICAL PATHOLOGY CLINICS\x0B | ix | ||
| FORTHCOMING ISSUES | ix | ||
| September 2017 | ix | ||
| December 2017 | ix | ||
| March 2018 | ix | ||
| RECENT ISSUES | ix | ||
| March 2017 | ix | ||
| December 2016 | ix | ||
| September 2016 | ix | ||
| Preface:\rDiagnostic Challenges in Dermatopathology | xi | ||
| Spitz Tumors of the Skin | 281 | ||
| ABSTRACT | 281 | ||
| OVERVIEW | 281 | ||
| SPITZ NEVUS: CLINICAL FEATURES | 282 | ||
| SPITZ NEVUS: HISTOLOGIC FEATURES | 282 | ||
| SPITZ NEVUS VARIANTS | 285 | ||
| MELANOCYTIC BRCA-ASSOCIATED INTRADERMAL TUMOR | 288 | ||
| SPITZOID MELANOMA: CLINICAL AND HISTOLOGIC FEATURES | 289 | ||
| SPITZ TUMORS OF UNCERTAIN MALIGNANT POTENTIAL | 290 | ||
| SPITZ TUMORS WITH INCOMPLETE METASTATIC POTENTIAL | 291 | ||
| NOVEL DIAGNOSTIC MODALITIES | 295 | ||
| NONMELANOCYTIC SIMULATORS OF SPITZ NEVUS AND SPITZOID MELANOMA | 296 | ||
| SUMMARY | 296 | ||
| REFERENCES | 296 | ||
| Advances in the Genetic Characterization of Cutaneous Mesenchymal Neoplasms | 299 | ||
| ABSTRACT | 299 | ||
| OVERVIEW | 299 | ||
| PSEUDOMYOGENIC HEMANGIOENDOTHELIOMA | 300 | ||
| EPITHELIOID HEMANGIOENDOTHELIOMA | 301 | ||
| HEMOSIDEROTIC FIBROLIPOMATOUS TUMOR | 305 | ||
| CONVENTIONAL FIBROUS HISTIOCYTOMA | 306 | ||
| EPITHELIOID FIBROUS HISTIOCYTOMA | 306 | ||
| CUTANEOUS MYOEPITHELIAL TUMORS | 307 | ||
| CLEAR CELL SARCOMA | 309 | ||
| SUMMARY | 313 | ||
| REFERENCES | 314 | ||
| Atypical Fibroxanthoma Revisited | 319 | ||
| ABSTRACT | 319 | ||
| OVERVIEW | 319 | ||
| CLINICAL FEATURES | 320 | ||
| HISTOPATHOLOGICAL FEATURES | 322 | ||
| IMMUNOHISTOCHEMICAL FEATURES | 322 | ||
| MOLECULAR FEATURES | 323 | ||
| DIFFERENTIAL DIAGNOSIS | 324 | ||
| MORPHOLOGIC VARIANTS | 325 | ||
| SPINDLE-CELL NONPLEOMORPHIC ATYPICAL FIBROXANTHOMA | 325 | ||
| CLEAR-CELL ATYPICAL FIBROXANTHOMA | 328 | ||
| PIGMENTED ATYPICAL FIBROXANTHOMA | 329 | ||
| MYXOID ATYPICAL FIBROXANTHOMA | 330 | ||
| OSTEOCLAST-LIKE GIANT-CELL RICH ATYPICAL FIBROXANTHOMA | 331 | ||
| KELOIDAL ATYPICAL FIBROXANTHOMA | 332 | ||
| GRANULAR CELL ATYPICAL FIBROXANTHOMA | 332 | ||
| PROBLEMATIC RELATIONSHIP OF ATYPICAL FIBROXANTHOMA AND PLEOMORPHIC DERMAL SARCOMA | 332 | ||
| REFERENCES | 334 | ||
| Cutaneous Malignant Peripheral Nerve Sheath Tumor | 337 | ||
| ABSTRACT | 337 | ||
| OVERVIEW | 337 | ||
| CUTANEOUS MALIGNANT PERIPHERAL NERVE SHEATH TUMOR | 338 | ||
| CUTANEOUS CONVENTIONAL MALIGNANT PERIPHERAL NERVE SHEATH TUMOR | 338 | ||
| Clinical Features | 338 | ||
| Pathologic Features | 338 | ||
| Immunohistochemical Features | 339 | ||
| Differential Diagnosis | 339 | ||
| CUTANEOUS EPITHELIOID MALIGNANT PERIPHERAL NERVE SHEATH TUMOR | 340 | ||
| Clinical Features | 340 | ||
| Pathologic Features | 340 | ||
| Immunohistochemical Features | 341 | ||
| Differential Diagnosis | 341 | ||
| REFERENCES | 342 | ||
| Histopathology of Spindle Cell Vascular Tumors | 345 | ||
| ABSTRACT | 345 | ||
| OVERVIEW | 345 | ||
| SPINDLE CELL HEMANGIOMA | 345 | ||
| ACQUIRED TUFTED ANGIOMA (ANGIOBLASTOMA OF NAKAGAWA) | 348 | ||
| KAPOSIFORM HEMANGIOENDOTHELIOMA | 351 | ||
| KAPOSI SARCOMA | 355 | ||
| ANGIOSARCOMA | 360 | ||
| REFERENCES | 364 | ||
| Sebaceous Neoplasms | 367 | ||
| ABSTRACT | 367 | ||
| OVERVIEW | 367 | ||
| PATHOGENESIS AND GENETIC ASPECTS OF SEBACEOUS TUMORS | 367 | ||
| MORPHOLOGIC CLUES AND IMMUNOHISTOCHEMICAL MARKERS OF SEBACEOUS DIFFERENTIATION | 368 | ||
| SEBACEOUS SKIN TUMORS AS MARKER LESIONS OF MUIR-TORRE SYNDROME I AND II | 369 | ||
| SEBACEOUS ADENOMA AND SEBACEOUS HYPERPLASIA | 371 | ||
| SEBACEOMA | 373 | ||
| Differential Diagnoses | 374 | ||
| PERIOCULAR SEBACEOUS CARCINOMA | 374 | ||
| Differential Diagnoses | 376 | ||
| EXTRAOCULAR SEBACEOUS CARCINOMA | 378 | ||
| Differential Diagnoses | 380 | ||
| SUMMARY | 380 | ||
| REFERENCES | 380 | ||
| Update on Malignant Sweat Gland Tumors | 383 | ||
| ABSTRACT | 383 | ||
| OVERVIEW | 383 | ||
| MICROCYSTIC ADNEXAL CARCINOMA | 384 | ||
| CLINICAL PRESENTATION | 384 | ||
| MICROSCOPIC FEATURES | 384 | ||
| BEHAVIOR AND TREATMENT | 384 | ||
| DIFFERENTIAL DIAGNOSIS | 384 | ||
| SQUAMOID ECCRINE DUCTAL CARCINOMA | 384 | ||
| CLINICAL PRESENTATION | 386 | ||
| MICROSCOPIC FEATURES | 386 | ||
| BEHAVIOR AND TREATMENT | 387 | ||
| DIFFERENTIAL DIAGNOSIS | 387 | ||
| “AGGRESSIVE” DIGITAL PAPILLARY ADENOCARCINOMA | 387 | ||
| CLINICAL PRESENTATION | 388 | ||
| MICROSCOPIC FEATURES | 389 | ||
| BEHAVIOR AND TREATMENT | 390 | ||
| DIFFERENTIAL DIAGNOSIS | 390 | ||
| SPIRADENOCARCINOMA AND CYLINDROCARCINOMA | 390 | ||
| CLINICAL PRESENTATION | 390 | ||
| MICROSCOPIC FEATURES | 393 | ||
| BEHAVIOR AND TREATMENT | 393 | ||
| DIFFERENTIAL DIAGNOSIS | 395 | ||
| REFERENCES | 397 | ||
| Merkel Cell Carcinoma | 399 | ||
| ABSTRACT | 399 | ||
| OVERVIEW | 399 | ||
| GROSS FEATURES | 399 | ||
| MICROSCOPIC FEATURES | 400 | ||
| DIFFERENTIAL DIAGNOSIS | 400 | ||
| BASAL CELL CARCINOMA | 400 | ||
| MELANOMA | 400 | ||
| METASTATIC NEUROENDOCRINE CARCINOMA | 400 | ||
| METASTATIC WELL-DIFFERENTIATED NEUROENDOCRINE TUMOR | 402 | ||
| EWING SARCOMA | 402 | ||
| LYMPHOMA | 402 | ||
| SEBACEOUS CARCINOMA | 402 | ||
| SQUAMOUS CELL CARCINOMA | 402 | ||
| DIAGNOSIS | 402 | ||
| PROGNOSIS | 404 | ||
| REFERENCES | 406 | ||
| Cutaneous Lymphomas with Cytotoxic Phenotype | 409 | ||
| ABSTRACT | 409 | ||
| OVERVIEW | 409 | ||
| KEY POINTS T-CELL AND NATURAL KILLER CELL SUBSETS | 411 | ||
| SUBCUTANEOUS PANNICULITIS-LIKE T-CELL LYMPHOMA | 411 | ||
| OVERVIEW | 411 | ||
| CLINICAL FEATURES | 411 | ||
| MICROSCOPIC FEATURES | 411 | ||
| PROGNOSIS | 412 | ||
| DIFFERENTIAL DIAGNOSIS | 412 | ||
| PRIMARY CUTANEOUS CD8+ AGGRESSIVE EPIDERMOTROPIC CYTOTOXIC T-CELL LYMPHOMAS | 413 | ||
| OVERVIEW | 413 | ||
| CLINICAL FEATURES | 413 | ||
| MICROSCOPIC FEATURES | 413 | ||
| PROGNOSIS | 413 | ||
| DIFFERENTIAL DIAGNOSIS | 413 | ||
| PRIMARY CUTANEOUS γ/δ T-CELL LYMPHOMA | 415 | ||
| OVERVIEW | 415 | ||
| CLINICAL FEATURES | 415 | ||
| MICROSCOPIC FEATURES | 416 | ||
| PROGNOSIS | 417 | ||
| DIFFERENTIAL DIAGNOSIS | 417 | ||
| PRIMARY CUTANEOUS ACRAL CD8+ T-CELL LYMPHOMA | 418 | ||
| OVERVIEW | 418 | ||
| CLINICAL FEATURES | 418 | ||
| HISTOLOGIC FEATURES | 419 | ||
| PROGNOSIS | 419 | ||
| DIFFERENTIAL DIAGNOSIS | 420 | ||
| MYCOSIS FUNGOIDES WITH CD8 PHENOTYPE | 420 | ||
| OVERVIEW | 420 | ||
| CLINICAL FEATURES | 421 | ||
| HISTOLOGIC FEATURES | 421 | ||
| PROGNOSIS | 422 | ||
| DIFFERENTIAL DIAGNOSIS | 422 | ||
| SUMMARY | 423 | ||
| ACKNOWLEDGMENTS | 424 | ||
| REFERENCES | 424 | ||
| Epstein-Barr Virus–associated Lymphoproliferative Disorders in the Skin | 429 | ||
| ABSTRACT | 429 | ||
| OVERVIEW | 429 | ||
| EPSTEIN-BARR VIRUS–ASSOCIATED B-CELL LYMPHOPROLIFERATIVE DISORDERS IN THE SKIN | 430 | ||
| EPSTEIN-BARR VIRUS–POSITIVE MUCOCUTANEOUS ULCER | 430 | ||
| LYMPHOMATOID GRANULOMATOSIS | 432 | ||
| EPSTEIN-BARR VIRUS–POSITIVE DIFFUSE LARGE B-CELL LYMPHOMA, NOT OTHERWISE SPECIFIED | 434 | ||
| DIFFERENTIAL DIAGNOSIS | 436 | ||
| EPSTEIN-BARR VIRUS–ASSOCIATED T-CELL/NATURAL KILLER–CELL PROLIFERATIONS ENCOUNTERED IN THE SKIN | 441 | ||
| HYDROA VACCINIFORME–LIKE LYMPHOPROLIFERATIVE DISORDER | 441 | ||
| EXTRANODAL NATURAL KILLER/T-CELL LYMPHOMA, NASAL TYPE | 443 | ||
| DIFFERENTIAL DIAGNOSIS | 446 | ||
| SUMMARY | 450 | ||
| REFERENCES | 450 | ||
| Cutaneous Pseudolymphoma | 455 | ||
| ABSTRACT | 455 | ||
| OVERVIEW | 455 | ||
| DEFINITION | 455 | ||
| CLASSIFICATION | 455 | ||
| DIAGNOSTIC APPROACH | 456 | ||
| CLINICAL COURSE AND TREATMENT | 456 | ||
| NODULAR PSEUDOLYMPHOMA | 456 | ||
| CUTANEOUS B-CELL PSEUDOLYMPHOMA | 457 | ||
| Clinical Findings | 457 | ||
| Histology | 457 | ||
| Immunohistochemistry and Molecular Diagnostics | 457 | ||
| Differential Diagnoses | 458 | ||
| BORRELIA-ASSOCIATED B-CELL PSEUDOLYMPHOMA | 459 | ||
| Clinical Findings | 459 | ||
| Histology | 459 | ||
| Immunohistochemistry and Molecular Diagnostics | 459 | ||
| Laboratory Tests | 460 | ||
| PSEUDOLYMPHOMA T-CELL AND MIXED PSEUDOLYMPHOMA | 460 | ||
| Clinical Findings | 460 | ||
| Histology | 460 | ||
| Immunohistochemistry and Molecular Diagnostics | 461 | ||
| Differential Diagnosis | 461 | ||
| CD30+ T-CELL PSEUDOLYMPHOMA | 462 | ||
| PSEUDO-MYCOSIS FUNGOIDES—HISTOLOGIC SIMULATORS OF MYCOSIS FUNGOIDES | 462 | ||
| HISTOLOGY | 462 | ||
| IMMUNOHISTOCHEMISTRY | 462 | ||
| DIFFERENTIAL DIAGNOSES | 463 | ||
| Lymphomatoid Contact Dermatitis | 463 | ||
| Lymphomatoid Drug Reaction | 463 | ||
| Actinic Reticuloid | 463 | ||
| CD8+ T-Cell Pseudolymphoma in Immunodeficiency | 466 | ||
| Borrelia-Associated T-Cell Pseudolymphoma | 467 | ||
| Papuloerythroderma Ofuji | 468 | ||
| Lymphocytic Infiltration of the Skin and Palpable Arciforme Migratory Erythema | 468 | ||
| Infections as Simulators of Lymphomas | 469 | ||
| Inflammatory Disorders as Simulators of T-Cell Lymphoma | 470 | ||
| OTHER PSEUDOLYMPHOMA (ALPHABETICAL ORDER) | 470 | ||
| ACRAL PSEUDOLYMPHOMATOUS ANGIOKERATOMA | 470 | ||
| ANGIOLYMPHOID HYPERPLASIA WITH EOSINOPHILIA | 470 | ||
| CUTANEOUS PLASMOCYTOSIS | 471 | ||
| LYMPHOPLASMACYTIC PLAQUE | 471 | ||
| Pseudolymphomatous Folliculitis | 472 | ||
| INTRAVASCULAR PSEUDOLYMPHOMA | 472 | ||
| REFERENCES | 473 | ||
| Histopathologic Spectrum of Connective Tissue Diseases Commonly Affecting the Skin | 477 | ||
| ABSTRACT | 477 | ||
| OVERVIEW | 477 | ||
| LUPUS ERYTHEMATOSUS | 478 | ||
| CLINICAL FEATURES | 478 | ||
| MICROSCOPIC FEATURES | 478 | ||
| HISTOLOGIC PATTERNS SEEN IN LUPUS ERYTHEMATOSUS | 478 | ||
| INTERFACE DERMATITIS | 478 | ||
| PANNICULITIS | 480 | ||
| THROMBOTIC VASCULOPATHY | 481 | ||
| VASCULITIS | 483 | ||
| NEUTROPHILIC DERMATOSIS | 484 | ||
| DIFFERENTIAL DIAGNOSIS | 487 | ||
| INTERFACE DERMATITIS | 487 | ||
| PANNICULITIS | 488 | ||
| THROMBOTIC VASCULOPATHY | 490 | ||
| VASCULITIS | 492 | ||
| NEUTROPHILIC DERMATOSIS | 493 | ||
| DIAGNOSIS | 495 | ||
| PROGNOSIS | 495 | ||
| DERMATOMYOSITIS | 496 | ||
| CLINICAL FEATURES | 496 | ||
| MICROSCOPIC FEATURES | 496 | ||
| HISTOLOGIC PATTERNS SEEN IN DERMATOMYOSITIS | 496 | ||
| Immunofluorescence of Autoimmune Bullous Diseases | 505 | ||
| ABSTRACT | 505 | ||
| OVERVIEW | 505 | ||
| DIRECT VERSUS INDIRECT IMMUNOFLUORESCENCE | 506 | ||
| PEMPHIGUS | 506 | ||
| PEMPHIGOID | 508 | ||
| SUMMARY | 510 | ||
| REFERENCES | 511 |