BOOK
Neurologic Manifestations of Rheumatic Diseases, An Issue of Rheumatic Disease Clinics of North America, E-Book
John Imboden | Sarah E. Goglin
(2017)
Additional Information
Book Details
Abstract
This issue of Rheumatic Disease Clinics, edited by Drs. John Imboden and Sarah Goglin, will cover a variety of important aspects of the neurological manifestations of rheumatic diseases. Topics discussed in the issue will include: Primary vasculitis of the central nervous system; Neurologic manifestations of primary Sjogren Syndrome; Neurologic manifestations of antiphospholipid antibody syndrome; Neurologic manifestations of rheumatoid arthritis and ankylosing spondylitis; Neuromyelitis optica; Neurosarcoid; Central nervous system infections associated with immunosuppressive therapy; and Neurologic manifestations of IgG4-related disease, among others.
Table of Contents
| Section Title | Page | Action | Price |
|---|---|---|---|
| Front Cover | Cover | ||
| Neurologic Manifestations of Rheumatic Diseases\r | i | ||
| Copyright\r | ii | ||
| Contributors | iii | ||
| CONSULTING EDITOR | iii | ||
| EDITORS | iii | ||
| AUTHORS | iii | ||
| Contents | v | ||
| Foreword: Neurologic Manifestations of Rheumatic Diseases | v | ||
| Preface: Neurologic Manifestations of Rheumatic Diseases | v | ||
| Primary Angiitis of the Central Nervous System | v | ||
| Neurologic Manifestations of Primary Sjögren Syndrome | v | ||
| Central Nervous System Manifestations of Systemic Lupus Erythematosus | v | ||
| Central Nervous System Manifestations of Antiphospholipid Syndrome | vi | ||
| Neurologic Manifestations of Rheumatoid Arthritis | vi | ||
| Central Nervous System Disease in Antineutrophil Cytoplasmic Antibody–associated Vasculitis | vi | ||
| Neuromyelitis Optica | vi | ||
| Neurosarcoidosis | vii | ||
| Central Nervous System Infections Associated with Immunosuppressive Therapy for Rheumatic Disease | vii | ||
| Neurologic Features of Immunoglobulin G4–related Disease | vii | ||
| Involvement of the Peripheral Nervous System in Polyarteritis Nodosa and Antineutrophil Cytoplasmic Antibody–associated Vas ... | viii | ||
| RHEUMATIC DISEASE CLINICS\rOF NORTH AMERICA\r | ix | ||
| FORTHCOMING ISSUES | ix | ||
| February 2018 | ix | ||
| May 2018 | ix | ||
| RECENT ISSUES | ix | ||
| August 2017 | ix | ||
| May 2017 | ix | ||
| February 2017 | ix | ||
| Foreword: Neurologic Manifestations of Rheumatic Diseases\r | xi | ||
| Preface:\rNeurologic Manifestations of Rheumatic Diseases | xiii | ||
| Primary Angiitis of the Central Nervous System | 503 | ||
| Key points | 503 | ||
| INTRODUCTION | 503 | ||
| HISTORICAL CONTEXT | 504 | ||
| EPIDEMIOLOGY | 504 | ||
| CLINICAL MANIFESTATIONS | 504 | ||
| Disease Subtypes | 505 | ||
| Granulomatous Angiitis of the Central Nervous System | 505 | ||
| Lymphocytic Angiitis of the Central Nervous System | 505 | ||
| Amyloid Beta-Related Angiitis | 506 | ||
| Mass-like Lesions | 506 | ||
| Spinal Cord Vasculitis | 507 | ||
| DIAGNOSTIC APPROACH | 507 | ||
| Serologic Tests | 507 | ||
| Lumbar Puncture | 507 | ||
| MRI | 507 | ||
| Magnetic Resonance Angiography and Computed Tomography Angiography | 508 | ||
| Conventional Cerebral Angiography | 508 | ||
| Brain Biopsy | 509 | ||
| TREATMENT | 509 | ||
| Remission Induction Therapy | 510 | ||
| Remission Maintenance Therapy | 510 | ||
| DIFFERENTIAL DIAGNOSIS | 510 | ||
| Reversible Cerebral Vasoconstriction Syndrome | 510 | ||
| Intravascular Lymphoma | 514 | ||
| SUMMARY | 515 | ||
| REFERENCES | 515 | ||
| Neurologic Manifestations of Primary Sjögren Syndrome | 519 | ||
| Key points | 519 | ||
| PERIPHERAL NEUROPATHY | 520 | ||
| Painful Sensory Neuropathy | 520 | ||
| “Pure” Small Fiber Dorsal Root Ganglionitis | 520 | ||
| “Mixed” Small and Large Fiber Dorsal Root Ganglionitis | 522 | ||
| Sensorimotor Polyneuropathy | 522 | ||
| Mononeuritis Multiplex | 522 | ||
| Cranial Neuropathies | 522 | ||
| Radiculoneuropathy | 523 | ||
| Autonomic Neuropathy | 523 | ||
| CENTRAL NERVOUS SYSTEM | 523 | ||
| Subacute Encephalopathy | 524 | ||
| Multiple Sclerosis–like Disease | 524 | ||
| Headache | 524 | ||
| Psychiatric Disease | 524 | ||
| Ischemic Stroke | 525 | ||
| MYOPATHY | 525 | ||
| Treatment | 525 | ||
| REFERENCES | 526 | ||
| Central Nervous System Manifestations of Systemic Lupus Erythematosus | 531 | ||
| Key points | 531 | ||
| INTRODUCTION | 531 | ||
| DEFINITION AND CLASSIFICATION | 532 | ||
| PATHOGENESIS OF NEUROPSYCHIATRIC SYSTEMIC LUPUS ERYTHEMATOSUS | 533 | ||
| Autoantibodies and Blood–Brain Barrier Dysfunction | 533 | ||
| Anti-DNA and Anti–N-Methyl-d-Aspartate Receptor Antibodies | 533 | ||
| Anti-P Antibodies | 533 | ||
| Antiphospholipid Antibodies | 534 | ||
| Cytokines | 534 | ||
| CLINICAL MANIFESTATIONS | 534 | ||
| Diffuse Manifestations | 534 | ||
| Cognitive Dysfunction | 534 | ||
| Acute Confusional State and Psychosis | 535 | ||
| Posterior Reversible Encephalopathy Syndrome | 535 | ||
| FOCAL MANIFESTATIONS | 536 | ||
| Stroke | 536 | ||
| Seizure | 536 | ||
| Transverse Myelitis | 537 | ||
| DIAGNOSTIC APPROACH AND DIFFERENTIAL DIAGNOSIS OF NEUROPSYCHIATRIC SYSTEMIC LUPUS ERYTHEMATOSUS | 537 | ||
| TREATMENT STRATEGIES OF NEUROPSYCHIATRIC SYSTEMIC LUPUS ERYTHEMATOSUS | 538 | ||
| OUTCOMES | 540 | ||
| SUMMARY | 540 | ||
| REFERENCES | 540 | ||
| Central Nervous System Manifestations of Antiphospholipid Syndrome | 547 | ||
| Key points | 547 | ||
| INTRODUCTION | 547 | ||
| CLINICAL MANIFESTATIONS | 548 | ||
| Cerebral Vascular Accident | 548 | ||
| Cognitive Impairment and Dementia | 549 | ||
| Venous Sinus Thrombosis | 550 | ||
| Seizures and Epilepsy | 550 | ||
| Chorea | 551 | ||
| Headache and Migraine | 551 | ||
| Multiple Sclerosis–like Disease | 551 | ||
| Neuropsychiatric Disease | 552 | ||
| CLASSIFICATION CRITERIA, LABORATORY, AND IMAGING FINDINGS | 552 | ||
| Classification Criteria for Antiphospholipid Syndrome and Laboratory Testing | 552 | ||
| Neuroimaging | 554 | ||
| Treatment | 555 | ||
| REFERENCES | 556 | ||
| Neurologic Manifestations of Rheumatoid Arthritis | 561 | ||
| Key points | 561 | ||
| INVOLVEMENT OF THE CERVICAL SPINE | 561 | ||
| Overview | 561 | ||
| Atlantoaxial Subluxation | 562 | ||
| Symptoms and Signs of Atlantoaxial Subluxation | 562 | ||
| Vertical Subluxation due to Atlantooccipital Arthritis | 563 | ||
| Subaxial Cervical Spine Subluxation | 563 | ||
| Imaging of the Cervical Spine in Rheumatoid Arthritis | 563 | ||
| The Effect of Disease-Modifying Antirheumatic Drugs and Biological Agents on Cervical Spine Disease | 566 | ||
| Nonoperative Management | 566 | ||
| Operative Management | 566 | ||
| Special Considerations | 567 | ||
| RHEUMATOID MENINGITIS | 567 | ||
| Overview | 567 | ||
| Presentation and Diagnosis of Rheumatoid Meningitis | 568 | ||
| Differential Diagnosis | 568 | ||
| Treatment of Rheumatoid Meningitis | 568 | ||
| COMPRESSION NEUROPATHIES | 569 | ||
| ISCHEMIC NEUROPATHY DUE TO RHEUMATOID VASCULITIS | 570 | ||
| REFERENCES | 570 | ||
| Central Nervous System Disease in Antineutrophil Cytoplasmic Antibodies–Associated Vasculitis | 573 | ||
| Key points | 573 | ||
| OVERVIEW | 573 | ||
| PITUITARY INVOLVEMENT | 574 | ||
| MENINGEAL INVOLVEMENT | 575 | ||
| CEREBRAL VASCULITIS | 576 | ||
| REFERENCES | 577 | ||
| Neuromyelitis Optica | 579 | ||
| Key points | 579 | ||
| INTRODUCTION | 579 | ||
| EPIDEMIOLOGY | 579 | ||
| PATHOPHYSIOLOGY | 580 | ||
| CLINICAL PRESENTATION | 581 | ||
| Transverse Myelitis | 581 | ||
| Optic Neuritis | 581 | ||
| Brainstem Syndromes | 583 | ||
| DIAGNOSTIC EVALUATION | 583 | ||
| Serum Aquaporin 4–Immunoglobulin G Testing | 583 | ||
| Cerebrospinal Fluid | 583 | ||
| Ophthalmologic Examination | 583 | ||
| Neuroimaging | 584 | ||
| DIAGNOSTIC CRITERIA | 584 | ||
| DIFFERENTIAL DIAGNOSIS | 584 | ||
| TREATMENT: ACUTE ATTACK | 584 | ||
| TREATMENT: ATTACK PREVENTION | 584 | ||
| Rituximab | 585 | ||
| Other Immunosuppressive Agents | 586 | ||
| EMERGING THERAPIES | 587 | ||
| Eculizumab | 587 | ||
| Tocilizumab | 587 | ||
| Novel Therapeutics Targeting Aquaporin 4–Immunoglobulin G and Aquaporin 4 | 588 | ||
| PROGNOSIS | 588 | ||
| REFERENCES | 588 | ||
| Neurosarcoidosis | 593 | ||
| Key points | 593 | ||
| INTRODUCTION | 593 | ||
| CLINICAL FEATURES | 593 | ||
| Cranial Neuropathy | 594 | ||
| Meningeal Involvement | 595 | ||
| Brain Parenchymal Disease | 595 | ||
| Neuroendocrinologic Dysfunction | 595 | ||
| Spinal Cord Disease | 596 | ||
| Peripheral Neuropathy | 596 | ||
| DIAGNOSTIC TESTS | 596 | ||
| Neuroimaging | 596 | ||
| Cerebrospinal Fluid Analysis | 599 | ||
| TREATMENTS | 600 | ||
| Glucocorticoids | 600 | ||
| Immunosuppressive Agents | 601 | ||
| Biologic Agents | 602 | ||
| SUMMARY | 602 | ||
| REFERENCES | 602 | ||
| Central Nervous System Infections Associated with Immunosuppressive Therapy for Rheumatic Disease | 607 | ||
| Key points | 607 | ||
| INTRODUCTION | 607 | ||
| Case 1 | 608 | ||
| Case 2 | 608 | ||
| Broadly Immunosuppressive Agents | 609 | ||
| Glucocorticoids | 609 | ||
| Methotrexate | 610 | ||
| Cyclophosphamide | 610 | ||
| Biologic Immunomodulatory Therapies | 611 | ||
| Tumor necrosis factor inhibitors | 611 | ||
| B cell–targeted agents | 613 | ||
| SUMMARY | 614 | ||
| REFERENCES | 614 | ||
| Neurologic Features of Immunoglobulin G4–Related Disease | 621 | ||
| Key points | 621 | ||
| INTRODUCTION | 621 | ||
| GENERAL CLINICAL FEATURES AND COMMON PRESENTATIONS | 622 | ||
| PATHOLOGIC FINDINGS | 622 | ||
| PATHOPHYSIOLOGY | 623 | ||
| SEROLOGY | 623 | ||
| CLINICAL AND RADIOLOGICAL PRESENTATIONS OF NEUROLOGIC IMMUNOGLOBULIN G4–RELATED DISEASE | 623 | ||
| MENINGEAL DISEASE | 624 | ||
| CEREBROSPINAL FLUID FINDINGS IN IMMUNOGLOBULIN G4–RELATED PACHYMENINGITIS | 626 | ||
| ORBITAL DISEASE | 626 | ||
| PITUITARY GLAND AND STALK DISEASE | 627 | ||
| PERIPHERAL NERVE DISEASE | 628 | ||
| CENTRAL NERVOUS SYSTEM PARENCHYMAL DISEASE | 629 | ||
| TREATMENT | 629 | ||
| REFERENCES | 629 | ||
| Involvement of the Peripheral Nervous System in Polyarteritis Nodosa and Antineutrophil Cytoplasmic Antibodies–Associated V ... | 633 | ||
| Key points | 633 | ||
| OVERVIEW | 633 | ||
| PATHOLOGIC FINDINGS | 634 | ||
| CLINICAL SYNDROMES | 634 | ||
| DIAGNOSIS | 634 | ||
| ELECTRODIAGNOSTIC STUDIES | 636 | ||
| NERVE BIOPSY | 636 | ||
| DIFFERENTIAL DIAGNOSIS | 637 | ||
| TREATMENT AND OUTCOMES | 637 | ||
| REFERENCES | 638 |