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Sleep in Older Adults, An Issue of Sleep Medicine Clinics, E-Book

Sleep in Older Adults, An Issue of Sleep Medicine Clinics, E-Book

Cathy A. Alessi | Jennifer L. Martin

(2018)

Additional Information

Book Details

Abstract

This issue of Sleep Medicine Clinics focuses on Sleep in Older Adults, with topics including: Sleep in Normal Aging; Insomnia in the Older Adult; Sleep Apnea in the Older Adult; Circadian Rhythm Sleep-Wake Disorders in the Older Adult; Restless Legs Syndrome; Periodic Limb Movement Disorder and Other Sleep Related Movement Disorders in the Older Adult; REM Sleep Behavior Disorder and Other Parasomnias in the Older Adult; Neurodegenerative Disorders and Sleep; Medical Conditions and Sleep in the Older Adult; Psychiatric Illness and Sleep in the Older Adult; Sleep and Cognition in the Older Adult; Sleep and Nocturia in the Older Adult; Sleep and Long Term Care; and Sleep in the Hospitalized Older Adult.

Table of Contents

Section Title Page Action Price
Front Cover Cover
Sleep in Older Adults\r i
Copyright\r ii
CME Accreditation Page iii
PROGRAM OBJECTIVE iii
TARGET AUDIENCE iii
LEARNING OBJECTIVES iii
ACCREDITATION iii
DISCLOSURE OF CONFLICTS OF INTEREST iii
UNAPPROVED/OFF-LABEL USE DISCLOSURE iii
TO ENROLL iii
METHOD OF PARTICIPATION iv
CME INQUIRIES/SPECIAL NEEDS iv
SLEEP MEDICINE CLINICS\r v
FORTHCOMING ISSUES v
June 2018 v
September 2018 v
December 2018 v
RECENT ISSUES v
December 2017 v
September 2017 v
June 2017 v
Contributors vii
CONSULTING EDITOR vii
EDITORS vii
AUTHORS vii
Contents xi
Preface: Sleep in Older Adults: Challenges and Opportunities xi
Sleep in Normal Aging xi
Insomnia in the Older Adult xi
Apnea in Older Adults xi
Circadian Rhythm Sleep-Wake Disorders in Older Adults xi
Parasomnias and Sleep-Related Movement Disorders in Older Adults xii
Neurodegenerative Disorders and Sleep xii
Chronic Medical Conditions and Sleep in the Older Adult xii
Psychiatric Illness and Sleep in Older Adults: Comorbidity and Opportunities for Intervention xii
Sleep and Cognition in Older Adults xiii
Sleep and Nocturia in Older Adults xiii
Sleep and Long-Term Care xiii
Sleep in Hospitalized Older Adults xiii
Preface:\rSleep in Older Adults: Challenges and Opportunities xv
Sleep in Normal Aging 1
Key points 1
INTRODUCTION 1
AGE-RELATED CHANGES IN SLEEP 1
Sleep Duration 2
Sleep Initiation 2
Sleep Efficiency 2
Sleep Maintenance 2
Sleep Stages 2
Daytime Napping and Daytime Sleepiness 3
Self-Reported Sleep Quality 4
AGE-RELATED CHANGES IN CIRCADIAN RHYTHMS 4
Phase Advance 4
Reduced Amplitude in Circadian Rhythms 4
Decreased Ability Adjusting to Phase Shifting 5
Changes in Sleep Homeostasis 5
SLEEP-RELATED HORMONES, AGING, AND SLEEP 5
Growth Hormone 5
Cortisol 6
Prolactin 6
Thyroid-Stimulating Hormone 6
Melatonin 6
Sex Hormones 6
RISK FACTORS FOR SLEEP DISTURBANCES IN OLDER ADULTS 6
Medical Comorbidities and Psychiatric Illness 7
Primary Sleep Disorders 7
Social, Lifestyle, and Environmental Factors 7
SUMMARY 7
REFERENCES 8
Insomnia in the Older Adult 13
Key points 13
INTRODUCTION 13
Prevalence and Diagnosis of Insomnia 13
Risk Factors of Insomnia 14
EVALUATION OF INSOMNIA 15
TREATMENTS FOR INSOMNIA 16
Nonpharmacologic Treatment Options 16
Pharmacologic Treatment Options 17
Comparative Effectiveness of Cognitive-Behavioral Therapy for Insomnia and Medications 18
SUMMARY 18
REFERENCES 18
Apnea in Older Adults 21
Key points 21
INTRODUCTION 21
EPIDEMIOLOGY 21
CLINICAL MANIFESTATIONS 22
DIAGNOSTIC TESTING 22
PATHOPHYSIOLOGY 22
CONSEQUENCES OF SLEEP-DISORDERED BREATHING IN OLDER ADULTS 23
Hypertension 24
Cardiovascular Events 24
Cerebrovascular Disease 29
Excessive Daytime Sleepiness and Cognitive Function 29
Depression 29
Type 2 Diabetes 29
Function and Quality of Life 32
THERAPY 32
Positive Airway Pressure Therapy 32
Oral appliance 32
SUMMARY 33
REFERENCES 33
Circadian Rhythm Sleep-Wake Disorders in Older Adults 39
Key points 39
INTRODUCTION 39
CIRCADIAN RHYTHM SLEEP-WAKE DISORDERS 40
THE CIRCADIAN TIMING SYSTEM IN HUMANS 40
CIRCADIAN REGULATION OF SLEEP AND WAKEFULNESS 40
AGE-RELATED CHANGES IN CIRCADIAN RHYTHMS 41
DIAGNOSIS OF CIRCADIAN RHYTHM SLEEP-WAKE DISORDERS 42
PREVALENCE OF CIRCADIAN RHYTHM SLEEP-WAKE DISORDERS IN OLDER ADULTS 42
NEUROLOGIC IMPLICATIONS OF CIRCADIAN RHYTHM CHANGES IN OLDER ADULTS 42
CIRCADIAN RHYTHM DISRUPTION IN OLDER PATIENTS WITH NEURODEGENERATIVE DISEASE 44
TREATMENT OF CIRCADIAN SLEEP-WAKE DISORDERS IN OLDER ADULTS 45
LIGHT THERAPY 45
TREATMENT OF IRREGULAR SLEEP-WAKE RHYTHM DISORDER IN OLDER ADULTS 45
TREATMENT OF SHIFT-WORK SLEEP DISORDER IN OLDER ADULTS 45
SUMMARY 46
ACKNOWLEDGMENTS 46
REFERENCES 46
Parasomnias and Sleep-Related Movement Disorders in Older Adults 51
Key points 51
INTRODUCTION 51
SLEEP PARALYSIS 51
DISORDERS OF AROUSALS 52
RAPID EYE MOVEMENT SLEEP BEHAVIOR DISORDER 52
Idiopathic Rapid Eye Movement Sleep Behavior Disorder 53
The Transition Between Idiopathic Rapid Eye Movement Sleep Behavior Disorder and Clinical Diagnosis of Parkinson Disease, D ... 53
Rapid Eye Movement Sleep Behavior Disorder in Patients Already Diagnosed with Parkinson Disease 54
Rapid Eye Movement Sleep Behavior Disorder in Patients Already Diagnosed with Multiple System Atrophy 55
Rapid Eye Movement Sleep Behavior Disorder in Patients Already Diagnosed with Dementia with Lewy Bodies 55
PARASOMNIA OVERLAP DISORDER 56
ANTI-IGLON5 DISEASE 56
RESTLESS LEGS SYNDROME 57
PERIODIC LIMB MOVEMENTS IN SLEEP 58
SUMMARY 59
REFERENCES 59
Neurodegenerative Disorders and Sleep 63
Key points 63
INTRODUCTION 63
PARKINSON DISEASE AND OTHER SYNUCLEINOPATHIES 63
Insomnia 64
Hypersomnia 65
Sleep-Disordered Breathing 66
Parasomnias 66
ALZHEIMER DEMENTIA AND OTHER TAUOPATHIES 67
Insomnia 67
Obstructive Sleep Apnea 68
PROGRESSIVE SUPRANUCLEAR PALSY 68
SUMMARY 68
REFERENCES 69
Chronic Medical Conditions and Sleep in the Older Adult 71
Key points 71
INTRODUCTION 71
CHRONIC MEDICAL CONDITIONS AND SLEEP INTERACTIONS 72
Pain 72
Clinical aspects and dual relationship between pain and sleep disturbance 72
Interventions to improve comorbid sleep disturbance and pain 73
Cancer 73
Clinical aspects and dual relationship between cancer and sleep disturbance 73
Interventions to improve sleep disturbance for patients with cancer 74
Falls 74
Clinical aspects and relationship between falls, insomnia, sedative drugs, and sleep apnea 74
Interventions to improve sleep disturbance in older fallers 75
Chronic Heart Failure 75
Clinical aspects and dual relationship between congestive heart failure and sleep disturbance 75
Interventions to improve sleep apnea (central and obstructive sleep apnea) for patients with congestive heart failure 76
SUMMARY 77
REFERENCES 77
Psychiatric Illness and Sleep in Older Adults 81
Key points 81
SLEEP DISTURBANCES AND DISORDERS 82
DEPRESSION AND SLEEP DISORDERS 82
Depression and Insomnia 82
Depression and Obstructive Sleep Apnea 82
Depression and Nightmares 84
Depression and Sleep Quality 84
ANXIETY AND SLEEP DISORDERS 84
Anxiety and Insomnia 84
Anxiety and Obstructive Sleep Apnea 85
Anxiety and Nightmares 85
SUICIDE AND SLEEP DISORDERS 85
Suicide and Insomnia 85
Suicide and Nightmares 86
Suicide and Obstructive Sleep Apnea 86
NEURODEGENERATIVE DISEASES AND SLEEP DISORDERS 86
Rapid Eye Movement Sleep Behavior Disorder and Parkinson Disease 86
Sleep in Dementia 86
SUMMARY 87
Summary of Findings and Conclusions 87
REFERENCES 88
Sleep and Cognition in Older Adults 93
Key points 93
INTRODUCTION 93
SLEEP AND COGNITION IN NORMAL-SLEEPING OLDER ADULTS 94
Self-Reported Sleep Duration and Cognition 94
Polysomnography-Measured Sleep and Cognition 94
Actigraphy-Measured Sleep and Cognition 94
Sleep Deprivation and Cognition 94
Sleep Restriction and Cognition 95
Sleep and Learning 95
SLEEP AND COGNITION IN OLDER ADULTS WITH INSOMNIA 95
Insomnia Status and Normal Cognitive Aging 95
Insomnia and Cognitive Decline/Dementia Diagnoses 96
Insomnia Treatment and Cognitive Functioning 97
SLEEP AND COGNITION IN OLDER ADULTS WITH SLEEP DISORDERED BREATHING 97
Sleep Disordered Breathing Severity and Cognitive Performance 100
Sleep Disordered Breathing Treatment and Cognitive Performance 102
UNIFYING THEORIES AND MECHANISMS 103
SUMMARY AND FUTURE DIRECTIONS 103
REFERENCES 103
Sleep and Nocturia in Older Adults 107
Key points 107
INTRODUCTION 107
MULTIFACTORIAL ASSESSMENT OF CONTRIBUTING CONDITIONS 107
Common Comorbid Conditions 107
Medication Review 108
Physical Examination and Clinical Evaluation 108
MULTICOMPONENT TREATMENT APPROACH 109
Lifestyle and Behavioral Treatment 109
Pharmacologic Treatment 110
Minimally Invasive and Surgical Treatment 113
SUMMARY 114
REFERENCES 114
Sleep and Long-Term Care 117
Key points 117
POOR SLEEP AND THE RISK OF LONG-TERM CARE PLACEMENT 117
SLEEP DISTURBANCE IN LONG-TERM CARE 118
CONSEQUENCES OF SLEEP DISTURBANCE IN LONG-TERM CARE 118
CLINICAL ASSESSMENT OF SLEEP DISTURBANCE IN LONG-TERM CARE 118
FACTORS THAT CONTRIBUTE TO SLEEP DISTURBANCE IN LONG-TERM CARE 118
Age-Related Factors 118
Environmental Factors 119
Behavioral Factors 119
Medical and Psychiatric Factors 119
MANAGEMENT OF SLEEP DISTURBANCE IN LONG-TERM CARE 120
Summary and Management Goals 120
Nonpharmacologic Strategies 120
Bright light 120
Exercise and social activity 120
Multicomponent interventions 121
Continuous positive airway pressure and other treatments for obstructive sleep apnea 121
Pharmacologic Strategies 122
Complementary and Alternative Treatments 122
Dietary and herbal supplements 122
Massage and acupressure 122
IMPLICATIONS FOR RESEARCH AND PRACTICE 122
Implications for Future Research 122
Recommendations for Practice 123
REFERENCES 123
Sleep in Hospitalized Older Adults 127
Key points 127
INTRODUCTION 127
SLEEP LOSS IN OLDER ADULTS 127
HEALTH EFFECTS OF SLEEP LOSS FOR HOSPITALIZED OLDER ADULTS 128
BARRIERS TO PROPER SLEEP FOR HOSPITALIZED OLDER ADULTS 129
Medical Care Interruptions 129
Patient Factors 129
Environmental Disruptions 129
PREVALENCE OF SLEEP DISORDERS AMONG HOSPITALIZED OLDER ADULTS 129
INTERVENTIONS TO IMPROVE SLEEP IN HOSPITALIZED ADULTS 130
Pharmacologic Interventions 130
Melatonin 130
Sleep aids 130
Pain treatment 131
Nonpharmacologic Interventions 131
Relaxation techniques 131
Sleep hygiene program 131
Bright light therapy 131
Noise reduction 132
Reducing nighttime interruptions 132
Sleep education and empowerment 132
Multifaceted Protocols 132
Assessment and Treatment of Underlying Sleep Disorders 132
SUMMARY 132
REFERENCES 132