BOOK
Bone Tumor Pathology, An Issue of Surgical Pathology Clinics, E-Book
(2017)
Additional Information
Book Details
Abstract
This issue of Surgical Pathology Clinics, edited by Dr. Judith V.M.G. Bovée, will discuss the latest updates in Bone Tumor Pathology. Topics covered in this issue include, but are not limited to Molecular pathology of bone tumors; Ewing sarcoma; Ewing-like tumors; Vascular tumors of bone; Giant cell containing tumours of bone; Cartilaginous tumours; bone forming tumours; jaw tumours, among others.
Table of Contents
| Section Title | Page | Action | Price |
|---|---|---|---|
| Front Cover | Cover | ||
| Bone Tumor Pathology | i | ||
| Copyright\r | ii | ||
| Contributors | iii | ||
| CONSULTING EDITOR | iii | ||
| EDITOR | iii | ||
| AUTHORS | iii | ||
| Contents | vii | ||
| Preface: Molecular pathology of bone tumors; what have we learned and how does it affect daily practice? | vii | ||
| Bone-Forming Tumors | vii | ||
| Integrating Morphology and Genetics in the Diagnosis of Cartilage Tumors | vii | ||
| Giant Cell–Containing Tumors of Bone | vii | ||
| Ewing Sarcoma, an Update on Molecular Pathology with Therapeutic Implications | vii | ||
| Update on Families of Round Cell Sarcomas Other than Classical Ewing Sarcomas | viii | ||
| Vascular Tumors of Bone: The Evolvement of a Classification Based on Molecular Developments | viii | ||
| Notochordal Tumors: An Update on Molecular Pathology with Therapeutic Implications | viii | ||
| Myoepithelial Tumors of Bone | viii | ||
| Hematopoietic Tumors Primarily Presenting in Bone | ix | ||
| Bone-Related Lesions of the Jaws | ix | ||
| Soft Tissue Tumors Rarely Presenting Primary in Bone; Diagnostic Pitfalls | ix | ||
| Conditions Simulating Primary Bone Neoplasms | ix | ||
| Tumor Syndromes That Include Bone Tumors: An Update | x | ||
| SURGICAL PATHOLOGY CLINICS\r | xi | ||
| FORTHCOMING ISSUES | xi | ||
| December 2017 | xi | ||
| March 2018 | xi | ||
| June 2018 | xi | ||
| RECENT ISSUES | xi | ||
| June 2017 | xi | ||
| March 2017 | xi | ||
| December 2016 | xi | ||
| Preface:\rMolecular Pathology of Bone Tumors: What Have We Learned and How Does It Affect Daily Practice? | xiii | ||
| REFERENCES | xiv | ||
| Bone-Forming Tumors | 513 | ||
| ABSTRACT | 513 | ||
| OVERVIEW | 513 | ||
| OSTEOID OSTEOMA | 513 | ||
| OSTEOBLASTOMA | 514 | ||
| FIBROUS DYSPLASIA | 517 | ||
| OSTEOSARCOMA | 520 | ||
| CONVENTIONAL OSTEOSARCOMA AND ITS HISTOLOGIC SUBTYPES | 521 | ||
| INTRAMEDULLARY WELL-DIFFERENTIATED OSTEOSARCOMA | 526 | ||
| SURFACE OSTEOSARCOMAS | 528 | ||
| REFERENCES | 534 | ||
| Integrating Morphology and Genetics in the Diagnosis of Cartilage Tumors | 537 | ||
| ABSTRACT | 537 | ||
| OVERVIEW | 537 | ||
| ENDOCHONDRAL BONE FORMATION | 538 | ||
| BENIGN CARTILAGE TUMORS | 538 | ||
| ENCHONDROMA | 538 | ||
| OSTEOCHONDROMA | 542 | ||
| MALIGNANT CARTILAGE TUMORS | 543 | ||
| HISTOLOGIC GRADING | 543 | ||
| CONVENTIONAL CENTRAL CHONDROSARCOMA | 544 | ||
| SECONDARY PERIPHERAL CHONDROSARCOMA | 545 | ||
| DEDIFFERENTIATED CHONDROSARCOMA | 547 | ||
| MESENCHYMAL CHONDROSARCOMA | 548 | ||
| CLEAR CELL CHONDROSARCOMA | 549 | ||
| PERIOSTEAL CHONDROSARCOMA | 549 | ||
| SUMMARY | 549 | ||
| REFERENCES | 550 | ||
| Giant Cell–Containing Tumors of Bone | 553 | ||
| ABSTRACT | 553 | ||
| OVERVIEW | 553 | ||
| GIANT CELL TUMOR OF BONE (GCTB) | 555 | ||
| RADIOGRAPHIC FEATURES | 555 | ||
| GROSS FEATURES | 555 | ||
| MICROSCOPIC FEATURES | 555 | ||
| MOLECULAR GENETIC FEATURES | 556 | ||
| PROGNOSIS AND TREATMENT | 557 | ||
| CHONDROBLASTOMA | 557 | ||
| RADIOLOGIC FEATURES | 557 | ||
| GROSS FEATURES | 557 | ||
| MICROSCOPIC FEATURES | 557 | ||
| MOLECULAR GENETIC FEATURES | 557 | ||
| PROGNOSIS AND TREATMENT | 559 | ||
| ANEURYSMAL BONE CYST (ABC) | 559 | ||
| RADIOLOGIC FEATURES | 559 | ||
| GROSS FEATURES | 559 | ||
| MICROSCOPIC FEATURES | 559 | ||
| MOLECULAR GENETIC FEATURES | 561 | ||
| PROGNOSIS | 561 | ||
| CHONDROMYXOID FIBROMA (CMF) | 561 | ||
| RADIOLOGIC FEATURES | 562 | ||
| GROSS FEATURES | 562 | ||
| MICROSCOPIC FEATURES | 562 | ||
| PROGNOSIS AND TREATMENT | 562 | ||
| NON-OSSIFYING FIBROMA (NOF) | 562 | ||
| RADIOLOGIC FEATURES | 563 | ||
| GROSS FEATURES | 563 | ||
| MICROSCOPIC FEATURES | 563 | ||
| PROGNOSIS AND TREATMENT | 563 | ||
| LANGERHANS CELL HISTIOCYTOSIS (LCH) | 563 | ||
| Ewing Sarcoma, an Update on Molecular Pathology with Therapeutic Implications | 575 | ||
| ABSTRACT | 575 | ||
| EWING SARCOMA | 575 | ||
| CLINICAL FEATURES | 576 | ||
| HISTOPATHOLOGY | 576 | ||
| IMMUNOHISTOCHEMISTRY | 577 | ||
| MOLECULAR PATHOLOGY | 579 | ||
| HOW TO USE ANCILLARY STUDIES FOR DIFFERENTIAL DIAGNOSIS | 579 | ||
| PROGNOSIS AND TREATMENT | 581 | ||
| PERSPECTIVES REGARDING NEW THERAPIES | 582 | ||
| REFERENCES | 584 | ||
| Update on Families of Round Cell Sarcomas Other than Classical Ewing Sarcomas | 587 | ||
| ABSTRACT | 587 | ||
| OVERVIEW | 587 | ||
| ROUND CELL SARCOMAS WITH EWSR1-REARRANGEMENTS INVOLVING NON–E26 TRANSFORMATION-SPECIFIC FUSION PARTNERS (EWSR1-NON ETS TRAN ... | 589 | ||
| CLINICAL FEATURES | 589 | ||
| MICROSCOPIC AND IMMUNOHISTOCHEMICAL FEATURES | 589 | ||
| EWSR1 REARRANGEMENTS | 589 | ||
| DIFFERENTIAL DIAGNOSIS | 591 | ||
| CAPICUA TRANSCRIPTIONAL REPRESSOR-REARRANGED ROUND CELL SARCOMAS (CAPICUA TRANSCRIPTIONAL REPRESSOR-SARCOMAS) | 592 | ||
| CLINICAL FEATURES | 593 | ||
| RADIOLOGICAL AND GROSS FEATURES | 593 | ||
| MICROSCOPIC FEATURES | 596 | ||
| IMMUNOHISTOCHEMICAL FEATURES | 596 | ||
| CAPICUA TRANSCRIPTIONAL REPRESSOR REARRANGEMENTS | 596 | ||
| MOLECULAR TESTING | 598 | ||
| DIFFERENTIAL DIAGNOSIS | 600 | ||
| MANAGEMENT AND PROGNOSIS | 604 | ||
| BCL6 COREPRESSOR-REARRANGED ROUND CELL SARCOMAS (BCL6 COREPRESSOR-ROUND CELL SARCOMAS) | 605 | ||
| CLINICAL FEATURES | 605 | ||
| RADIOLOGICAL AND GROSS FEATURES | 605 | ||
| MICROSCOPIC FEATURES | 605 | ||
| IMMUNOHISTOCHEMICAL FEATURES | 605 | ||
| BCL6 COREPRESSOR REARRANGEMENTS | 607 | ||
| MOLECULAR TESTING | 612 | ||
| Fluorescence In Situ Hybridization | 612 | ||
| Reverse-Transcriptase Polymerase Chain Reaction | 613 | ||
| Array-Comparative Genomic Hybridization | 613 | ||
| DIFFERENTIAL DIAGNOSIS | 614 | ||
| MANAGEMENT AND PROGNOSIS | 616 | ||
| UNDIFFERENTIATED/UNCLASSIFIED SMALL ROUND CELL SARCOMAS | 618 | ||
| SUMMARY | 619 | ||
| REFERENCES | 619 | ||
| Vascular Tumors of Bone | 621 | ||
| ABSTRACT | 621 | ||
| OVERVIEW | 621 | ||
| IMMUNOHISTOCHEMISTRY | 622 | ||
| HEMANGIOMA | 622 | ||
| DEFINITION, EPIDEMIOLOGY, AND CLINICAL FEATURES | 622 | ||
| HISTOLOGIC AND IMMUNOHISTOCHEMISTRY FEATURES | 624 | ||
| EPITHELIOID HEMANGIOMA | 624 | ||
| DEFINITION, EPIDEMIOLOGY, AND CLINICAL FEATURES | 624 | ||
| HISTOLOGIC AND IMMUNOHISTOCHEMISTRY FEATURES | 625 | ||
| Notochordal Tumors | 637 | ||
| ABSTRACT | 637 | ||
| OVERVIEW | 637 | ||
| BENIGN NOTOCHORDAL CELL TUMOR | 639 | ||
| Myoepithelial Tumors of Bone | 657 | ||
| ABSTRACT | 657 | ||
| OVERVIEW, HISTORICAL PERSPECTIVE | 657 | ||
| EPIDEMIOLOGY, SITES OF INVOLVEMENT, AND GROSS FEATURES | 657 | ||
| MICROSCOPIC FEATURES AND DIAGNOSIS | 658 | ||
| DIFFERENTIAL DIAGNOSIS | 661 | ||
| PROGNOSIS | 671 | ||
| REFERENCES | 674 | ||
| Hematopoietic Tumors Primarily Presenting in Bone | 675 | ||
| ABSTRACT | 675 | ||
| OVERVIEW | 675 | ||
| PLASMA CELL MYELOMA | 675 | ||
| RADIOLOGIC AND GROSS FEATURES | 676 | ||
| MICROSCOPY | 676 | ||
| DIFFERENTIAL DIAGNOSIS | 676 | ||
| DIAGNOSIS | 678 | ||
| Bone-Related Lesions of the Jaws | 693 | ||
| ABSTRACT | 693 | ||
| OVERVIEW AND DEVELOPMENTAL CONSIDERATIONS | 693 | ||
| FIBRO-OSSEOUS LESIONS | 694 | ||
| CEMENTO-OSSEOUS DYSPLASIA | 694 | ||
| CEMENTO-OSSIFYING FIBROMA | 694 | ||
| FIBROUS DYSPLASIA | 697 | ||
| GIANT CELL–CONTAINING LESIONS | 698 | ||
| CENTRAL GIANT CELL GRANULOMA | 698 | ||
| ANEURYSMAL BONE CYST | 700 | ||
| CHERUBISM | 700 | ||
| BONE-FORMING TUMORS | 701 | ||
| OSTEOMA | 701 | ||
| OSTEOID OSTEOMA AND OSTEOBLASTOMA | 701 | ||
| OSTEOSARCOMA | 701 | ||
| REFERENCES | 703 | ||
| Soft Tissue Tumors Rarely Presenting Primary in Bone; Diagnostic Pitfalls | 705 | ||
| ABSTRACT | 705 | ||
| OVERVIEW | 705 | ||
| LEIOMYOSARCOMA | 706 | ||
| UNDIFFERENTIATED PLEOMORPHIC SARCOMA | 709 | ||
| MYXOFIBROSARCOMA | 711 | ||
| SYNOVIAL SARCOMA | 712 | ||
| SOLITARY FIBROUS TUMOR | 717 | ||
| SCLEROSING EPITHELIOID FIBROSARCOMA | 720 | ||
| PSEUDOMYOGENIC HEMANGIOENDOTHELIOMA | 723 | ||
| MYOEPITHELIAL NEOPLASM | 725 | ||
| SUMMARY | 728 | ||
| REFERENCES | 729 | ||
| Conditions Simulating Primary Bone Neoplasms | 731 | ||
| ABSTRACT | 731 | ||
| OVERVIEW | 731 | ||
| STRESS FRACTURES | 731 | ||
| RADIOLOGIC FEATURES | 732 | ||
| MICROSCOPIC FEATURES | 732 | ||
| DIFFERENTIAL DIAGNOSIS | 732 | ||
| SUBCHONDRAL (SUBARTICULAR) CYSTS | 732 | ||
| RADIOLOGIC FEATURES | 734 | ||
| MICROSCOPIC FEATURES | 734 | ||
| DIFFERENTIAL DIAGNOSIS | 734 | ||
| OSTEONECROSIS | 734 | ||
| RADIOLOGIC FEATURES | 737 | ||
| MICROSCOPIC FEATURES | 738 | ||
| DIFFERENTIAL DIAGNOSIS | 738 | ||
| HETEROTOPIC OSSIFICATION | 738 | ||
| RADIOLOGY | 739 | ||
| MICROSCOPY | 739 | ||
| DIFFERENTIAL DIAGNOSIS | 739 | ||
| OSTEOMYELITIS | 741 | ||
| RADIOLOGIC FINDINGS | 743 | ||
| MICROSCOPIC FEATURES | 744 | ||
| DIFFERENTIAL DIAGNOSIS | 744 | ||
| SKELETAL SARCOIDOSIS | 745 | ||
| MICROSCOPIC FEATURES | 745 | ||
| DIFFERENTIAL DIAGNOSIS | 745 | ||
| AMYLOIDOMA | 746 | ||
| MICROSCOPIC FEATURES | 747 | ||
| SUMMARY | 747 | ||
| REFERENCES | 747 | ||
| Tumor Syndromes That Include Bone Tumors | 749 | ||
| ABSTRACT | 749 | ||
| OVERVIEW | 749 | ||
| TUMOR SYNDROMES AND OSTEOSARCOMA | 750 | ||
| LI-FRAUMENI SYNDROME | 750 | ||
| RETINOBLASTOMA | 753 | ||
| ROTHMUND-THOMSON SYNDROME | 754 | ||
| WERNER SYNDROME | 756 | ||
| SYNDROMES WITH INCREASED RISK FOR CHONDROSARCOMAS | 757 | ||
| MULTIPLE OSTEOCHONDROMAS | 758 | ||
| ENCHONDROMATOSIS (OLLIER DISEASE AND MAFFUCCI SYNDROME) | 759 | ||
| OTHER GENETIC SYNDROMES WITH OSTEOSARCOMA AND CHONDROSARCOMA | 760 | ||
| REFERENCES | 762 |