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Book Details
Abstract
Visually stunning and easy to use, this volume in the highly regarded Diagnostic Pathology series covers the normal histology of every organ system. This edition incorporates the most recent scientific and technological knowledge in the field to provide a comprehensive overview of all areas of normal histology, including introductory chapters on electron microscopy, immunofluorescence, immunohistochemistry and histochemistry, the cell, and the basic organization of tissues. With nearly 1,800 outstanding images, this reference is an invaluable diagnostic aid for every practicing pathologist, resident, or fellow.
- Unparalleled visual coverage with carefully annotated photomicrographs, spectacular gross images, electron micrographs, and medical illustrations
- Time-saving reference features include bulleted text, a variety of test data tables, key facts in each chapter, annotated images, and an extensive index
- Thoroughly updated content throughout , with all-new chapters on synovium and histologic artifacts, a thoroughly revised skeletal muscle chapter that now addresses normal histology in the setting of neuromuscular biopsy, and coverage of additional histologic variations that cause diagnostic confusion
- New content on immunohistochemistry; more image examples of newly recognized normal variations, mimics, and pitfalls; and expanded text in many sections for greater clarity and ease of reference
Table of Contents
| Section Title | Page | Action | Price |
|---|---|---|---|
| Front Cover\r | Cover | ||
| Diagnostic Pathology: Normal Histology | ii | ||
| Copyright Page | iv | ||
| Dedication | v | ||
| Preface | vii | ||
| Acknowledgments | ix | ||
| Sections | xi | ||
| Table of Contents | xii | ||
| SECTION 1:\rIntroduction to Normal Histology and\rBasic Histological Techniques | 3 | ||
| Chapter 1.\rIntroduction to the Cell | 4 | ||
| TERMINOLOGY | 4 | ||
| OVERVIEW OF CELL ORGANIZATION | 4 | ||
| NUCLEUS | 4 | ||
| CYTOPLASM | 4 | ||
| CYTOSKELETON | 5 | ||
| CELL ADHESION | 5 | ||
| EXTRACELLULAR SUBSTANCES | 5 | ||
| Chapter\r2. Introduction to Histology | 12 | ||
| TERMINOLOGY | 12 | ||
| TYPES OF TISSUE | 12 | ||
| ORGAN SYSTEMS | 14 | ||
| Chapter\r3. General Histologic Artifacts | 22 | ||
| TERMINOLOGY | 22 | ||
| COMMON ARTIFACTS | 22 | ||
| Chapter\r4. Histochemistry (Special Stains) | 24 | ||
| TERMINOLOGY | 24 | ||
| NUCLEAR AND CYTOPLASMIC STAINING | 24 | ||
| CARBOHYDRATE STAINS | 24 | ||
| CONNECTIVE TISSUE STAINS | 25 | ||
| MUSCLE STAINS | 25 | ||
| FAT STAINS | 25 | ||
| NERVE STAINS | 25 | ||
| PIGMENTS, MINERALS, AND GRANULES | 25 | ||
| MISCELLANEOUS STAINS | 25 | ||
| Chapter\r5. Immunohistochemistry of Normal Tissues | 28 | ||
| TERMINOLOGY | 28 | ||
| GENERAL CATEGORIES OF\rIMMUNOHISTOCHEMICAL ANTIBODIES | 28 | ||
| ANTIGENIC PROPERTIES OF SELECTED\rORGANS AND TISSUES | 29 | ||
| Chapter\r6. Immunofluorescence | 32 | ||
| TERMINOLOGY | 32 | ||
| METHODOLOGY | 32 | ||
| ASSESSMENT OF CLINICAL SPECIMENS | 33 | ||
| SELECTED REFERENCES | 33 | ||
| Chapter\r7. Electron Microscopy | 36 | ||
| TERMINOLOGY | 36 | ||
| SPECIMEN HANDLING | 36 | ||
| ELECTRON MICROSCOPY ASSESSMENT OF\rCLINICAL SAMPLES | 36 | ||
| SELECTED REFERENCES | 37 | ||
| SECTION 2: Integument | 41 | ||
| Chapter\r8. Epidermis (Including Keratinocytes and Melanocytes) | 42 | ||
| EPIDERMIS | 42 | ||
| CONSIDERATIONS AND VARIATIONS | 42 | ||
| Chapter\r9. Dermis | 46 | ||
| DERMIS | 46 | ||
| CONSIDERATIONS AND VARIATIONS | 46 | ||
| Chapter\r10. Adnexal Structures | 50 | ||
| ADNEXAL STRUCTURES | 50 | ||
| CONSIDERATIONS AND VARIATIONS | 50 | ||
| Chapter\r11. Nail | 54 | ||
| NAIL | 54 | ||
| CONSIDERATIONS AND VARIATIONS | 54 | ||
| SECTION 3: Musculoskeletal System | 57 | ||
| Chapter\r12. Bone and Cartilage | 58 | ||
| BONE | 58 | ||
| CARTILAGE | 58 | ||
| CONSIDERATIONS AND VARIATIONS | 58 | ||
| Chapter\r13. Synovial Membrane | 66 | ||
| SYNOVIAL MEMBRANE | 66 | ||
| CONSIDERATIONS AND VARIATIONS | 66 | ||
| Chapter\r14. Connective Tissue | 68 | ||
| CONNECTIVE TISSUE | 68 | ||
| CONSIDERATIONS AND VARIATIONS | 68 | ||
| Chapter\r15. Adipose Tissue | 72 | ||
| ADIPOSE TISSUE | 72 | ||
| CONSIDERATIONS AND VARIATIONS | 72 | ||
| Chapter\r16. Skeletal Muscle | 76 | ||
| SKELETAL MUSCLE | 76 | ||
| VARIATIONS AND CONSIDERATIONS | 76 | ||
| SECTION 4: Circulatory System | 83 | ||
| Chapter\r17. Heart | 84 | ||
| HEART | 84 | ||
| CONSIDERATIONS AND VARIATIONS | 84 | ||
| Chapter\r18. Cardiac Valves | 88 | ||
| CARDIAC VALVES | 88 | ||
| CONSIDERATIONS AND VARIATIONS | 88 | ||
| Chapter\r19. Cardiac Conduction System | 90 | ||
| CARDIAC CONDUCTION SYSTEM | 90 | ||
| CONSIDERATIONS AND VARIATIONS | 90 | ||
| Chapter\r20. Arteries | 94 | ||
| ARTERIES | 94 | ||
| CONSIDERATIONS AND VARIATIONS | 94 | ||
| Chapter\r21. Capillaries, Veins, and Lymphatics | 98 | ||
| CAPILLARIES | 98 | ||
| VEINS | 98 | ||
| LYMPHATICS | 98 | ||
| CONSIDERATIONS AND VARIATIONS | 98 | ||
| SECTION 5: Nervous System | 103 | ||
| Chapter\r22. Peripheral Nervous System | 104 | ||
| PERIPHERAL NERVOUS SYSTEM | 104 | ||
| CONSIDERATIONS AND VARIATIONS | 104 | ||
| Chapter\r23. Central Nervous System | 108 | ||
| CENTRAL NERVOUS SYSTEM | 108 | ||
| CONSIDERATIONS AND VARIATIONS | 108 | ||
| Chapter\r24. Meninges | 112 | ||
| MENINGES | 112 | ||
| CONSIDERATIONS AND VARIATIONS | 112 | ||
| Chapter\r25. Choroid Plexus | 114 | ||
| CHOROID PLEXUS | 114 | ||
| CONSIDERATIONS AND VARIATIONS | 114 | ||
| SECTION 6: Hematopoietic and Immune Systems | 117 | ||
| Chapter\r26. Overview of Immune System | 118 | ||
| TERMINOLOGY | 118 | ||
| COMPONENTS OF INNATE IMMUNE SYSTEM | 119 | ||
| COMPONENTS OF ADAPTIVE IMMUNE\rSYSTEM | 120 | ||
| CLINICAL IMPLICATIONS | 120 | ||
| LYMPHOID ORGANS | 121 | ||
| BONE MARROW | 121 | ||
| THYMUS | 121 | ||
| Chapter\r27. Lymph Nodes | 122 | ||
| LYMPH NODES | 122 | ||
| CONSIDERATIONS AND VARIATIONS | 122 | ||
| Chapter\r28. Spleen | 126 | ||
| SPLEEN | 126 | ||
| CONSIDERATIONS AND VARIATIONS | 126 | ||
| Chapter\r29. Bone Marrow | 130 | ||
| BONE MARROW | 130 | ||
| CONSIDERATIONS AND VARIATIONS | 130 | ||
| Chapter\r30. Peripheral Blood | 138 | ||
| PERIPHERAL BLOOD | 138 | ||
| CONSIDERATIONS AND VARIATIONS | 138 | ||
| Chapter\r31. Thymus | 142 | ||
| THYMUS | 142 | ||
| CONSIDERATIONS AND VARIATIONS | 142 | ||
| SECTION 7:\rHead and Neck | 147 | ||
| Chapter\r32. Eye and Ocular Adnexa | 148 | ||
| EYE | 148 | ||
| OCULAR ADNEXA | 148 | ||
| CONSIDERATIONS AND VARIATIONS | 148 | ||
| Chapter\r33. Oral Mucosae | 158 | ||
| ORAL MUCOSAE | 158 | ||
| CONSIDERATIONS AND VARIATIONS | 158 | ||
| Chapter\r34. Gingivae | 160 | ||
| GINGIVAE | 160 | ||
| CONSIDERATIONS AND VARIATIONS | 160 | ||
| Chapter\r35. Teeth | 162 | ||
| TEETH | 162 | ||
| CONSIDERATIONS AND VARIATIONS | 162 | ||
| Chapter\r36. Tongue | 166 | ||
| TONGUE | 166 | ||
| CONSIDERATIONS AND VARIATIONS | 166 | ||
| Chapter\r37. Tonsils/Adenoids | 170 | ||
| TONSILS/ADENOIDS | 170 | ||
| CONSIDERATIONS AND VARIATIONS | 170 | ||
| Chapter\r38. Ear | 174 | ||
| EAR | 174 | ||
| CONSIDERATIONS AND VARIATIONS | 174 | ||
| Chapter\r39. Nose and Paranasal Sinuses | 178 | ||
| NOSE | 178 | ||
| PARANASAL SINUSES | 178 | ||
| Chapter\r40. Minor Salivary Glands | 182 | ||
| MINOR SALIVARY GLANDS | 182 | ||
| CONSIDERATIONS AND VARIATIONS | 182 | ||
| Chapter\r41. Major Salivary Glands | 184 | ||
| MAJOR SALIVARY GLANDS | 184 | ||
| CONSIDERATIONS AND VARIATIONS | 184 | ||
| Chapter\r42. Pharynx | 188 | ||
| PHARYNX | 188 | ||
| Chapter\r43. Larynx | 190 | ||
| LARYNX | 190 | ||
| CONSIDERATIONS AND VARIATIONS | 190 | ||
| SECTION 8: Respiratory System | 195 | ||
| Chapter\r44. Trachea | 196 | ||
| TRACHEA | 196 | ||
| CONSIDERATIONS AND VARIATIONS | 196 | ||
| Chapter\r45. Lung | 198 | ||
| LUNG | 198 | ||
| PITFALLS/ARTIFACTS | 198 | ||
| Chapter\r46. Pleura and Pericardium | 206 | ||
| PLEURA AND PERICARDIUM | 206 | ||
| CONSIDERATIONS AND VARIATIONS | 206 | ||
| SECTION 9: Breast\r | 209 | ||
| Chapter\r47. Breast | 210 | ||
| BREAST | 210 | ||
| CONSIDERATIONS AND VARIATIONS | 210 | ||
| SECTION 10: Tubular Gut and Peritoneum | 217 | ||
| Chapter\r48. Esophagus | 218 | ||
| ESOPHAGUS | 218 | ||
| VARIATIONS AND CONSIDERATIONS | 218 | ||
| Chapter\r49. Stomach | 224 | ||
| STOMACH | 224 | ||
| CONSIDERATIONS AND VARIATIONS | 224 | ||
| Chapter\r50. Small Intestine | 232 | ||
| SMALL INTESTINE | 232 | ||
| CONSIDERATIONS AND VARIATIONS | 232 | ||
| Chapter\r51. Large Intestine | 238 | ||
| LARGE INTESTINE (COLON) | 238 | ||
| CONSIDERATIONS AND VARIATIONS | 238 | ||
| Chapter\r52. Appendix | 246 | ||
| APPENDIX | 246 | ||
| CONSIDERATIONS AND VARIATIONS | 246 | ||
| Chapter\r53. Anus and Anal Canal | 252 | ||
| ANUS AND ANAL CANAL | 252 | ||
| CONSIDERATIONS AND VARIATIONS | 252 | ||
| Chapter\r54. Peritoneum | 256 | ||
| PERITONEUM | 256 | ||
| CONSIDERATIONS AND VARIATIONS | 256 | ||
| SECTION 11: Hepatobiliary Tract and Pancreas | 259 | ||
| Chapter\r55. Liver | 260 | ||
| LIVER | 260 | ||
| CONSIDERATIONS AND VARIATIONS | 260 | ||
| Chapter\r56. Gallbladder | 268 | ||
| GALLBLADDER | 268 | ||
| CONSIDERATIONS AND VARIATIONS | 268 | ||
| Chapter\r57. Extrahepatic Biliary Tract | 272 | ||
| EXTRAHEPATIC BILIARY TREE | 272 | ||
| CONSIDERATIONS AND VARIATIONS | 272 | ||
| Chapter\r58. Vaterian System | 276 | ||
| VATERIAN SYSTEM | 276 | ||
| Chapter\r59. Pancreas | 278 | ||
| PANCREAS | 278 | ||
| CONSIDERATIONS AND VARIATIONS | 278 | ||
| SECTION 12: Genitourinary and Male Genital Tract | 285 | ||
| Chapter\r60. Kidney | 286 | ||
| KIDNEY | 286 | ||
| CONSIDERATIONS AND VARIATIONS | 286 | ||
| Chapter\r61. Ureter and Renal Pelvis | 296 | ||
| URETER | 296 | ||
| RENAL PELVIS | 296 | ||
| CONSIDERATIONS AND VARIATIONS | 296 | ||
| Chapter\r62. Bladder | 300 | ||
| BLADDER | 300 | ||
| CONSIDERATIONS AND VARIATIONS | 300 | ||
| Chapter\r63. Urethra | 306 | ||
| URETHRA | 306 | ||
| CONSIDERATIONS AND VARIATIONS | 306 | ||
| Chapter\r64. Prostate: Regional Anatomy With Histologic Correlates | 312 | ||
| PROSTATE | 312 | ||
| CONSIDERATIONS AND VARIATIONS | 312 | ||
| Chapter\r65. Prostate: Benign Glandular and Stromal Histology | 322 | ||
| PROSTATE | 322 | ||
| CONSIDERATIONS AND VARIATIONS | 322 | ||
| Chapter\r66. Penis | 332 | ||
| PENIS | 332 | ||
| Chapter\r67. Testis and Associated Excretory Ducts | 336 | ||
| TESTIS | 336 | ||
| CONSIDERATIONS AND VARIATIONS | 336 | ||
| SECTION 13: Female Genital Tract | 345 | ||
| Chapter\r68. Vulva | 346 | ||
| VULVA | 346 | ||
| CONSIDERATIONS AND VARIATIONS | 346 | ||
| Chapter\r69. Vagina | 350 | ||
| VAGINA | 350 | ||
| CONSIDERATIONS AND VARIATIONS | 350 | ||
| Chapter\r70. Uterus | 354 | ||
| UTERUS | 354 | ||
| CONSIDERATIONS AND VARIATIONS | 354 | ||
| Chapter\r71. Fallopian Tube | 368 | ||
| FALLOPIAN TUBE | 368 | ||
| CONSIDERATIONS AND VARIATIONS | 368 | ||
| Chapter\r72. Ovary | 374 | ||
| OVARY | 374 | ||
| CONSIDERATIONS AND VARIATIONS | 374 | ||
| Chapter\r73. Placenta | 384 | ||
| PLACENTA | 384 | ||
| CONSIDERATIONS AND VARIATIONS | 384 | ||
| SECTION 14: Endocrine | 391 | ||
| Chapter\r74. Adrenal Gland | 392 | ||
| ADRENAL GLAND | 392 | ||
| CONSIDERATIONS AND VARIATIONS | 392 | ||
| Chapter\r75. Paraganglia | 398 | ||
| PARAGANGLIA | 398 | ||
| CONSIDERATIONS AND VARIATIONS | 398 | ||
| Chapter\r76. Thyroid | 400 | ||
| THYROID | 400 | ||
| Chapter\r77. Parathyroid | 404 | ||
| PARATHYROID | 404 | ||
| CONSIDERATIONS AND VARIATIONS | 404 | ||
| Chapter\r78. Pineal Gland | 408 | ||
| PINEAL GLAND | 408 | ||
| CONSIDERATIONS AND VARIATIONS | 408 | ||
| Chapter\r79. Pituitary | 410 | ||
| PITUITARY | 410 | ||
| CONSIDERATIONS AND VARIATIONS | 410 | ||
| INDEX | I-i |