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Obstetrics & Gynecology Morning Report: Beyond the Pearls E-Book

Obstetrics & Gynecology Morning Report: Beyond the Pearls E-Book

Kate V. Meriwether | Joey England | Rajkumar Dasgupta | R. Michelle Koolaee

(2018)

Additional Information

Book Details

Abstract

Concise and easy to read, Obstetrics & Gynecology Morning Report: Beyond the Pearls is a case-based reference that covers the key material included on the USMLE Step 2 and Step 3, as well as the OB-GYN clerkship. Focusing on the practical information you need to know, it teaches how to analyze a clinical vignette in the style of a morning report conference, sharpening your clinical decision-making skills and helping you formulate an evidence-based approach to realistic patient scenarios.


Table of Contents

Section Title Page Action Price
Front Cover Cover
IFC\r ES1
OBSTETRICS & GYNECOLOGY MORNING REPORT: Beyond the Pearls\r i
Copyright ii
Dedication iii
LIST OF CONTRIBUTORS iv
PREFACE x
FOREWORD xi
CONTENTS xii
1 - A 34-Year-Old Woman With Cervical Dysplasia in Pregnancy\r 1
What is the etiology of cervical cancer? 1
What are the vaccination options for cervical cancer? 2
What are screening recommendations for cervical cancer? 2
What are the recommendations for management of HSIL in the nonpregnant woman? 2
How is a colposcopy performed? 2
What additional considerations are made in pregnancy? 3
How do you counsel this patient about her biopsy results? 4
How should her cervical dysplasia affect her mode of delivery? 5
Does the patient’s cervical dysplasia limit her options for postpartum contraception? 5
What are your options for management? 5
What is the follow-up plan for this patient? 6
Case Summary 7
References 7
2 - A 23-Year-Old Woman with Hyperemesis Gravidarum\r 8
What questions should be asked when interviewing this patient? 8
What should the physical exam include? 9
What is the differential diagnosis? 9
What is the working diagnosis? 10
What laboratory evaluation and radiologic testing should be performed on this patient? 10
What is the etiology of NVP? 11
What are the risk factors for NVP? 12
How is NVP treated? 12
What is the more severe form of NVP? 14
Case Summary 14
References 14
3 - A 31-Year-Old Woman With Rash in Pregnancy\r 16
When a pregnant woman develops blisters, what is important to know in her history? 16
What clues in the history point away from a diagnosis of allergic contact dermatitis? 17
What clues in the patient’s history could point toward a diagnosis of an arthropod assault? 18
What clues in this patient’s history might point toward gestational pemphigoid? 20
What treatment options can begin before the patient sees the dermatologist? 22
She is curious if this condition will recur in future pregnancies; what advice can you give her? 24
Case Summary 24
References 24
4 - A 38-Year-Old Woman with GDM\r 26
What is GDM? 26
What are some relevant questions in your history that might suggest GDM? 26
What risk factors does this patient have for GDM? 27
Who should be screened for GDM? 27
How is GDM diagnosed? 27
What are the risks of untreated GDM? 31
Is antenatal testing indicated with GDM? 31
How should labor and delivery be managed in patients with GDM? 32
How should the patient be managed postpartum? 32
Case Summary 33
Resources 33
References 33
5 - A 27-Year-Old Woman With Human Immunodeficiency Virus in Pregnancy\r 34
Describe the pertinent history and physical examination for the patient with HIV 34
What laboratory evaluation provides the diagnosis for HIV? 35
What provides the diagnosis for acquired immune deficiency syndrome (AIDS)? 36
What laboratory, imaging studies, and management should be pursued? 37
What is the treatment for HIV during pregnancy? 37
For decreasing CD4 counts, what is the appropriate prophylaxis? 37
How do you counsel the patient postpartum? 38
Case Summary 38
References 39
6 - A 30-Year-Old Woman With Gestational Trophoblastic Disease\r 40
What is the initial differential diagnosis for the patient? 40
What laboratory, imaging studies, and management should be pursued? 41
What is your diagnosis? 41
Case Summary 43
References 44
7 - A 28-Year-Old Woman Presenting With Symptoms of Depression in the Postpartum Period\r 45
Why is it important to ask about and discuss emotional health in postpartum women? 45
Is it baby blues, depression, or psychosis? 45
What are additional questions you need answered at this point? 47
What immediate interaction and treatment should you undertake? 48
What referral and long-term treatment is appropriate? 49
Case Summary 50
References 50
8 - A 25-Year-Old Woman With Pica in Pregnancy\r 51
How does this information help you form a differential diagnosis? 52
What are the concerns that arise with the consumption of soils or “magnesia”? 52
Is consuming so much ice of concern? 54
How do you approach treating the underlying iron deficiency? 55
How do you approach addressing the actual pica substances? 56
How do you approach her long-term care? 57
Case Summary 57
References 58
9 - A 27-Year-Old Woman With Opiate Dependence in Pregnancy\r 59
Why is it important to screen for opioid abuse in pregnancy? 59
What is a validated method to screen for substance abuse in pregnancy? 59
Based on the history and physical exam for this patient, what is her COWS score? 62
What are the goals of treatment for opioid dependence in pregnancy? 62
What is NAS? 63
What additional testing should you perform prior to initiation of methadone therapy? 64
How should methadone opioid replacement therapy be initiated? 64
What additional care will your patient need throughout her pregnancy? 64
Case Summary 65
References 65
10 - A 29-Year-Old G1P0 Woman With Hypothyroidism in Pregnancy\r 67
What important questions should be asked to rule out other diagnoses? 67
What is your differential diagnosis at this point? 67
Does the thyroid exam have to be abnormal for thyroid disease? 68
What if a palpable nodule was noted on her thyroid exam? 68
What changes in the thyroid occur in pregnancy? 69
How important is treatment for overt hypothyroidism in pregnancy? 70
What can happen if overt hypothyroidism is not treated in pregnancy? 70
How would you approach treatment? 70
How do you adjust medication during pregnancy? 70
What do you do if she experiencing symptoms of overtreatment? 71
What nutritional requirements are there in pregnancy related to the thyroid? 71
What is the patient’s prognosis? 71
Case Summary 72
References 73
11 - A 30-Year-Old Woman Undergoes Carrier Screening\r 74
When is the optimal time to discuss the reported family history? 74
What genetic testing is typically available in the preconception period? 74
What is CF? 74
What is this patient’s risk to be a carrier and have a child with CF? 75
What testing should be offered to this patient? 76
Should you offer carrier screening for additional conditions? 77
Based on these results, what is this patient’s risk of having an affected child with CF? 78
What CF carrier screening, genotyping, or sequencing would you offer to the partner? 78
What is fragile X syndrome? 79
Should you offer to test the patient’s partner to see if he is a carrier for fragile X syndrome? 79
What does it mean to be an intermediate carrier for fragile X? 80
Is testing for fragile X syndrome recommended at delivery? 80
What is the most appropriate next step? 81
Should you recommend that they do not attempt a pregnancy? 81
Case Summary 81
References 82
12 - A 36-Year-Old Woman With 83
Why is it important to ask about headache in pregnancy? 83
In addition to her headache, what other information should be gathered from this patient? 83
Are there any fetal considerations that need to be evaluated? 84
What is your diagnosis at this time, and how would you manage her? 85
Are there any special considerations for her postpartum care? 86
What does the patient need to do at home, and can this happen again in a future pregnancy? 86
Case Summary 87
References\r 88
13 - A 20-Year-Old Woman With Preterm Premature Rupture of Membranes\r 89
What is the differential diagnosis during pregnancy for suspected vaginal loss of fluid? 89
What is the next step in evaluating this patient? 89
What is the appropriate laboratory and imaging evaluation? 90
What is your diagnosis? 90
What are the etiology and risk factors for PPROM? 91
How do you counsel the patient regarding this diagnosis? 91
What is the next step in management? 91
Describe the management of labor, delivery, and postpartum care for patients with PPROM 92
How do you counsel the patient regarding future pregnancy? 92
Case Summary 93
Acts of Grace Foundation 94
References 94
14 - A 36-Year-Old Woman at 33 Weeks’ Gestation With Bleeding\r 95
How does this information help you narrow your differential diagnosis? 95
How do you assess a patient like this in triage? 96
What laboratory values or imaging should you obtain? 96
What other complications can arise from a placenta previa? 97
What are the classifications of placenta previa? 97
What other life-threatening causes must be considered? 98
Case Summary 100
References 100
15 - A 36-Year-Old Woman With Placental Abruption\r 101
What lab evaluation is necessary? 101
What imaging would you like to perform for this patient? 102
What is your next step in management? 105
How do you diagnose disseminated intravascular coagulation? 105
What measures do you need to take to treat her DIC? 106
Case Summary 107
References 107
16 - A 35-Year-Old Woman With Lower Extremity Swelling\r 108
What are important questions to ask women in the puerperium period with leg swelling? 108
What clues in the history and exam will help you to narrow your differential diagnosis? 109
What further studies will you order? 109
What are the treatment options? 111
What further workup would you order? 112
What would be your next step of management? 112
Case Summary 114
References 114
17 - A 31-Year-Old Woman Admitted for Induction of Labor\r 115
What is induction of labor? 115
What are the reasons for inducing labor in a pregnant woman? 115
What are the contraindications to induction of labor? 115
How can the likelihood of a successful induction be determined? 116
What is cervical ripening, and how can it be performed? 117
What are the risks associated with cervical ripening and induction of labor? 117
What are some important criteria to consider (and document) before labor is induced? 120
How should this patient’s tachysystole and abnormal fetal heart rate be managed? 120
How is a failed induction diagnosed? 121
Case Summary 121
References 122
18 - A 35-Year-Old Pregnant Woman With Abdominal Pain\r 123
What are the imperative questions to ask in the patient who presents with abdominal pain? 123
How does the clinical picture develop in a patient with appendicitis? 123
What should be considered in your differential diagnosis? 124
What laboratory changes are associated with appendicitis? 126
What imaging studies are useful in diagnosing appendicitis? 126
Diagnosing acute appendicitis in a pregnant patient 128
What is the treatment of choice for a pregnant female with appendicitis? 128
Case Summary 129
References 129
19 - A 32-Year-Old Woman With Severe Postpartum Headache\r 131
What is the first step in evaluating the patient with a postpartum headache? 131
What are the diagnostic criteria by the International Headache Society? 131
Why is it important to elicit a history of headache? 132
How does this information help you form a differential diagnosis? 132
What is the anatomy of the spinal tract? 133
What other types of headaches have to be considered? 133
What is the pathophysiology of PDPH? 135
How do you treat this patient who complains of severe headache? 135
What is an EBP, and how is it performed? 136
How does EBP work? 136
What are the risks and benefits of an EBP? 136
What is your differential diagnosis at this point? 136
What would you do if she returned in a few days with a recurrence of the headache? 137
Case Summary 137
References 137
20 - A 25-Year-Old Woman With Obesity in Pregnancy\r 138
On presentation to prenatal care, what is the first assessment? 138
What are the goals during her first prenatal visit? 139
What are complications of obesity during pregnancy? 139
What are the recommendations for weight gain during pregnancy in obese women? 140
For patients with obesity, what type of skin incision is preferred during a cesarean delivery? 140
Are there any long-term implications of obesity on the women’s health? 140
What has been the impact of bariatric surgery on the health of a woman of reproductive age? 141
What is bariatric surgery? What are the types and their risk and benefit profiles? 141
Case Summary 142
References 142
21 - A 33-year-Old Woman With Postpartum Vaginal Edema\r 144
What is your differential diagnosis? 144
What is the initial management? 145
How would you manage the patient now? 146
Case Summary 148
References 148
22 - A 16-Year-Old Girl With Diabetic Ketoacidosis in Pregnancy\r 149
What is most likely causing this patient’s lethargy? 149
What other important questions or findings will help in our differential? 149
With the information provided, what is the likely diagnosis? 150
What is the clinical presentation of DKA? 151
What are the precipitating factors for the development of DKA? 152
23 - A 38-Year-Old Woman With Abnormal Quad Screen\r 157
What is prenatal genetic screening? What are its objectives? 157
Compare the various genetic screening methods during pregnancy 157
What are integrated, sequential, and contingent screenings? 158
What is the management plan for the patient? 158
What are the risk factors for Down syndrome in the fetus? 161
What is the significance of an increased NT finding in the first trimester? 161
What is a cystic hygroma? 161
With its high sensitivity and specificity, why can’t NIPT replace invasive diagnostic tests? 162
How does multifetal gestation affect the screening test’s performance? 162
Case Summary 163
References 163
24 - A 17-Year-Old Woman With a History of Sickle-Cell Disease Presenting With Bone Pain\r 164
What clues in the history and physical point to the diagnosis of SCD crisis? 165
How would you treat this patient? 165
How should you counsel the patient’s family? 166
Will the patient get a blood transfusion? 167
How do we manage SCD pain? 168
Will the patient require a cesarean delivery? 168
What are the postpartum recommendations for patients with SCD? 168
What type of contraception can be utilized in patients with SCD? 168
Case Summary 169
References 169
25 - A 28-Year-Old Woman With Valvular Heart Disease in Pregnancy\r 170
What is the differential diagnosis of a systolic murmur? 171
What cardiac exam findings will be altered during pregnancy? 171
Do heart murmurs during pregnancy require a workup? 171
What workup should be performed to evaluate a concerning heart murmur in pregnancy? 172
How common is aortic stenosis in pregnancy, and what are the common causes? 172
Should you be concerned about aortic stenosis in pregnancy? 172
How can pregnancy outcomes with aortic stenosis be predicted? 172
What workup should be performed for a pregnant patient with aortic stenosis? 172
What cardiac testing will be altered in pregnancy? 173
What is the familial inheritance risk of a bicuspid aortic valve? 173
How should a pregnant patient with aortic stenosis be managed during pregnancy? 173
Is surgical repair of aortic stenosis recommended during pregnancy? 173
How should women with aortic stenosis be delivered? 174
What is the role of a preconceptional counseling visit in women with valvular heart disease? 174
How should mechanical valves be monitored during pregnancy? 175
What anticoagulant should be used in pregnant women with prosthetic valves? 175
How should other valvular diseases in pregnancy be managed? 176
Case Summary 178
References 178
26 - A 25-Year-Old Woman Undergoes Noninvasive Aneuploidy Screening\r 179
What is noninvasive aneuploidy screening? 179
What facts and questions do you include in your counseling session? 180
What is the significance of these results? 180
What additional testing can be offered to diagnose or rule out Down syndrome? 180
Case Summary 183
References 183
27 - A 27-Year-Old Woman With Vaginal Bleeding in Pregnancy\r 184
Why is it important to ask about vaginal bleeding in pregnant women? 184
What are the risk factors for this finding? What are the conditions associated with it? 184
What is your differential diagnosis? 185
Case Summary 189
References 189
28 - A 27-Year-Old Woman With History of Asthma\r 190
What is asthma and its clinical presentation? 190
How is asthma diagnosed? 191
How is asthma treated? 192
What is the significance of asthma classification and approach to management? 193
What is the normal physiology of the respiratory system during pregnancy? 195
What is the effect of pregnancy on asthma? 196
What is the effect of asthma on pregnancy? 196
How does management differ for the pregnant patient with asthma? 197
What is status asthmaticus? 197
What is the optimal ventilator strategy for an acute asthma exacerbation? 198
Case Summary 199
References 200
29 - A 34-Year-Old Woman With Sleep Disturbance During Pregnancy\r 201
Are there physiologic reasons that OSA would be worse during pregnancy? 202
What are the testing options to diagnose sleep apnea? 204
What are the health risks associated with untreated OSA? 204
Are there any additional potential risks of untreated OSA to the mother that should be consideredin a patient who is pregnant?\r 204
Are there any potential risks of untreated OSA to the fetus? 205
What are the treatment options for OSA? Are there any specific recommendations for treatmentduring pregnancy?\r 205
Are there specific instructions you would give to this woman regarding her delivery and postpartum recovery with regard to her OSA?\r 206
Will OSA that was diagnosed during pregnancy “resolve” after pregnancy is over? 206
Case Summary 207
References 207
30 - A 25-Year-Old Woman in Her Third Trimester of Pregnancy\r 208
How does a prior history of SLE nephritis impact pregnancy? 208
What does the specific history of class IV nephritis mean for her pregnancy? 209
When is it safe for patients with SLE to become pregnant? 210
When should referral to a maternal–fetal medicine (MFM) specialist be considered? 210
How do you interpret her autoantibody profile as it relates to her pregnancy? 210
What is neonatal lupus? 211
What causes congenital heart block to occur? 212
What is the risk of her child developing cardiac neonatal lupus? 213
How does her historical treatment course impact her current pregnancy? 213
Are her current medications safe? 214
In a patient with a history of lupus nephritis, what specific physical exam findings should you look for?\r 214
What is your differential diagnosis based on the laboratory testing? 215
On inpatient admission, the primary team asks whether additional labs are warranted. What labs should be recommended and why?\r 215
What other antibodies would be useful to evaluate this patient? 216
How do you interpret this new information and additional labs from Table 30.8 and Figs. 30.5 and 30.6?\r 216
When would a repeat renal biopsy be indicated? 218
What are some other management considerations in patients with lupus nephritis in pregnancy?\r 220
Case Summary 220
References 221
31 - A 29-Year-Old Woman With Systemic Lupus Erythematosus Planning Pregnancy\r 222
How does SLE affect fertility and pregnancy? 223
Does this patient have active lupus? If so, how can you tell? 223
What immunosuppressive medications are safe to be given during pregnancy? 224
What immunosuppressive medications are safe to be given during pregnancy?\r 224
How should her mild arthritic flare be treated now that she is pregnant? 226
What medications should be avoided at this time for treatment of her arthritis? 226
Is it advisable for this patient to breastfeed? 227
Case Summary 228
References 228
32 - A 29-Year-Old Woman With Shortness of Breath\r 230
What is the differential diagnosis of SOB in pregnancy? 230
How does heart failure present on physical exam? 231
What is pulmonary hypertension? 231
What is the best screening test for pulmonary hypertension? 233
What is the most specific test for pulmonary hypertension? 235
What is the pathogenesis of PAH? 235
What are targeted therapies for PAH? 237
How does pregnancy impact PAH? 239
Case Summary 240
References 240
33 - A 42-Year-Old With Heavy Vaginal Bleeding\r 241
What are the next steps in evaluating this patient? 241
What is the definition of abnormal menstrual bleeding, and what are the causes? 242
What is the best imaging test to evaluate this patient’s abnormal physical exam? 242
What is the diagnosis? How do you counsel the patient about the ultrasound? 242
What are fibroids, and how are they related to bleeding and symptoms? 242
How are fibroids related to hormones? 243
What are the next steps in managing this patient’s bleeding and acute anemia? 243
Case Summary 245
References 245
34 - A 38-Year-Old Woman With Acute Pelvic Pain\r 246
What is your initial differential diagnosis? 246
Why is it important to consider the age of the patient? 246
What other risk factors should you ask about in the history? 247
What negative physical exam findings are important in this case? 247
Which laboratory test should be ordered for this patient? 248
What type of imaging test should be ordered for this patient’s evaluation? 248
Based upon this information, what is the most likely diagnosis in this patient? 250
How are adnexal masses categorized? 250
Case Summary 251
References 251
35 - A 17-Year-Old Girl With Recent Onset of Pelvic Pain\r 253
What are common causes of pelvic pain in a young female? 253
What should be done to evaluate this patient? 253
What is pelvic inflammatory disease? 254
How does PID present? What are the risks of not recognizing PID? 254
What history is needed when PID is suspected, and what are risk factors for PID? 254
What makes a patient a candidate for empiric treatment of PID? 256
How can the patient reduce her risk for recurrent PID? How does this affect her future fertility?\r 256
What contraception is safe for a woman with PID? 256
Case Summary 258
References 258
36 - A 28-Year-Old Woman With Abdominal Pain and Vaginal Bleeding\r 259
What are your differential diagnoses for this patient? 259
What is your next step in the evaluation of this patient? 259
Based on these findings, what diagnoses are possible or likely? 260
What physical exam findings would be concerning for an ectopic pregnancy? 260
What would be your concerns about observing this patient further? 262
Is medical management an option for this patient? 262
What is the patient’s diagnosis? 263
How would you counsel a patient with one former ectopic pregnancy and unilateral salpingectomy about future pregnancy?\r 263
Case Summary 264
References 264
37 - A 19-Year-Old With Postoperative Fever and Lower Abdominal Pain\r 265
What is the differential diagnosis for this patient? 265
What are the next steps in the patient’s evaluation? 266
What is the most likely cause of this patient’s symptoms? 267
What factors lead to increased risk for postabortal endometritis? 267
Could this postabortal endometritis have been prevented? 267
How is postabortal endometritis treated? 268
When should she follow up with her provider? 268
Why is it important to treat postabortal endometritis? 268
Could this patient have had postabortal placement of an intrauterine device (IUD)? 268
Case Summary 269
References 269
38 - A 34-Year-Old Woman With Postoperative Flank Pain\r 270
What is your differential diagnosis for this patient? 270
How do you classify the different types of urinary incontinence? 271
What is the most likely cause of the patient’s urinary incontinence? 272
What test can you do in the office to specifically evaluate this patient for a fistula? 272
What was the sequence of events that led to the formation of this patient’s fistula? 272
What patient and surgical factors lead to an increased risk of fistula formation? 273
What other imaging would be merited on suspicion of a vesico-vaginal or uretero-vaginal fistula?\r 273
How do you approach treatment of uretero-vaginal fistula? 273
How do you follow this patient after discharge? 274
Case Summary 275
References 275
39 - A 35-Year-Old Woman With an Abnormal Pap Smear\r 276
What are the risk factors for an abnormal Pap smear? 276
How do providers manage abnormal Pap smears? 277
How would you describe a colposcopy experience to a patient? 278
How would you prepare yourself, the examiner, to perform a colposcopy? 278
What is the transformation zone (TZ), and what is its role in colposcopy? 278
How do solutions applied to the cervix highlight lesions or dysplasia on colposcopy? 278
What if no lesions are seen on the colposcopic view of the cervix? 279
What descriptors are used to describe colposcopic lesions, and what is most concerning? 279
How is a cervical biopsy performed? 279
What different results might be seen on cervical biopsy? 279
What types of treatment are available? 280
Which types of dysplasia should be treated? 280
Case Summary 281
References 281
40 - A 28-Year-Old Woman With a History of Pulmonary Embolism Who Desires Contraception\r 282
What are the risk factors for venous thromboembolism (VTE)? 282
What tests should be ordered to evaluate for familial thrombophilic syndrome? 282
How should this patient be counseled regarding contraception recommendations? 283
What are the recommendations for a family history of VTE? 283
What should you tell the patient about hormone-containing methods? 283
What other reliable, progestin-only options are available for this patient? 284
What recommendations should be given to patients with thrombophilias and contraceptive management in the perioperative period? 285
Case Summary 286
References 286
41 - A 56-Year-Old Woman With Menopausal Symptoms\r 287
What history is necessary in a patient with these symptoms? 287
How is menopause defined, and what are the associated symptoms? 287
What are the physical exam findings in a postmenopausal patient? 288
What laboratory evaluation is indicated in a patient with menopausal symptoms? 288
What is the treatment of menopause, and when should it initiated? 288
When is hormone replacement therapy contraindicated? 289
What are alternatives to HRT for postmenopausal symptoms? 289
Are there advantages to HRT other than symptom control? 290
When should the patient consider stopping her estrogen? 290
Case Summary 291
References 291
42 - A 22-Year-Old Woman With Painful Menses\r 292
What is your differential diagnosis for this patient? 292
What factors of the history can differentiate these three diagnoses on the differential? 292
What types of laboratory testing or imaging studies would be useful for this patient? 293
How do you next counsel your patient? 293
What is the next step in management? 294
What surgical options should you discuss with her? 295
What is long-term follow-up for this patient? 295
Case Summary 296
For Further Reading 296
43 - A 26-Year-Old Woman With Irregular Menses\r 297
What additional information would you want to know from the patient? 297
What is the differential diagnosis for irregular menstrual bleeding? 297
What should you look for in the physical exam? 297
What is the pathophysiology of hirsutism, and what are some common causes? 298
How would you make a diagnosis of PCOS? 299
What comorbidities are associated with PCOS, and how can you screen for them? 299
What PCOS therapies are available to patients who do not currently desire pregnancy? 300
How would you manage hirsutism in a woman with PCOS? 300
What therapies are available for PCOS patients who currently desire pregnancy? 301
What are some important recommendations that you want to review with her? 301
Case Summary 302
References 302
44 - A 25-Year-Old With Recurrent Pregnancy Loss\r 303
What additional information do you want from this patient? 303
What would be your working diagnosis based on the information that you have on hand? 304
What are common causes of RPL? 304
What testing would you recommend for this patient for her RPL? 305
What do you recommend next? 305
How would you advise her on trying to get pregnant again? 305
Case Summary 307
References 308
45 - A 17-Year-Old Girl With Absent Menses\r 309
What other questions do you want to ask this patient? 309
How should one approach the diagnosis in primary amenorrhea? 309
What would be the most likely cause of amenorrhea in our patient? 310
What are the physical exam findings to look for when evaluating primary amenorrhea? 310
What labs should be part of her initial workup? 311
What additional workup would you like to order for this patient? 311
What physical exam findings are commonly seen in Turner syndrome? 311
What treatment options are available for her? 313
How would you counsel this patient about attempting pregnancy in the future? 313
Case Summary 314
References\r 314
46 - A 33-Year-Old Woman With Infertility and Endometriosis\r 315
What additional questions would you want to ask this patient? 315
What would be your working diagnosis based on this information? 316
What are common causes of infertility? 316
What testing would you recommend to this patient? 317
What would you recommend for this patient? 318
What would you discuss next with this patient? 318
What do you recommend next for this patient? 318
Case Summary 319
References 319
47 - A 22-Year-Old Woman With Amenorrhea\r 321
What is the difference between primary and secondary amenorrhea? 321
How is galactorrhea related to hyperprolactinemia? 321
What medications can cause amenorrhea? 322
What are the next steps in evaluation? 322
What are causes of hyperprolactinemia? 323
What if the patient is taking a medication that may elevate her prolactin? 323
What are secretory or pituitary tumor causes of hyperprolactinemia? 323
What is the next step in management? 324
How long should the patient continue her dopamine agonist? 324
What are contraindications to dopamine agonist therapy? 324
How should women be counseled about prepregnancy planning? 324
How are prolactinomas monitored during pregnancy? 324
How are growing, symptomatic prolactinomas treated during pregnancy? 325
Case Summary 326
References 326
48 - A 3-Year-Old Girl With Vaginal Discharge\r 327
How is the prepubertal genital tract different from older pubertal females? 327
What is the differential diagnosis of vulvovaginal symptoms in a prepubertal child? 328
Following a thorough history, how will you perform a physical exam? 328
What tests should you obtain? 329
How should the foreign body found on physical exam be removed? 330
How would the evaluation change if the parents reported continued vaginal bleeding and no foreign object was found in the vagina?\r 330
What after-care information should be provided to the patient’s parents? 331
Case Summary 331
References 331
49 - A 15-Year-Old Concerned About Not Having Her Period\r 332
When should delayed menarche be evaluated? 332
What is the most common cause of primary amenorrhea? 332
What is the differential diagnosis in this case? 332
What is the next step in evaluation? 334
What is this patient’s diagnosis, and what is the etiology? 334
What is the recommended treatment for this patient? 334
What are this patient’s fertility options? 335
What if the patient had no pubic hair but a short (2 cm) vagina? What is the most likely diagnosis in this scenario?\r 335
What is the pathophysiology of CAIS and the associated karyotype? 335
How do you counsel an adolescent with MRKH about sexuality? 336
Case Summary 336
References 337
50 - A 14-Year-Old Girl With Heavy Menstrual Bleeding Since Menarche\r 338
What additional history would be helpful to assess this patient? 338
What is in the differential diagnosis of abnormal uterine bleeding in an adolescent? 339
Should this patient be evaluated for a bleeding disorder? 340
How is iron deficiency anemia treated? 341
What is the pathophysiology of von Willebrand disease? 341
How should the patient’s heavy menses be treated? 342
What are the risks and benefits of combined OCPs? 342
How can acute, heavy vaginal bleeding be managed in an adolescent patient? 342
Case Summary 343
References 343
51 - An 11-Year-Old With Gender Identity Concerns\r 344
What is gender dysphoria? 344
What are the initial steps in caring for this patient? 344
How does the onset of puberty affect the management of this patient? 345
Is any additional history needed for this patient? 345
What medical treatment options are available to transgender patients? 346
Does hormonal treatment have an effect on future fertility? What are this patient’s options? 347
What surgical options are available to transgender patients? 347
What long-term health considerations need to be discussed specific to transgender patients? 347
Case Summary 349
References 349
52 - A 65-Year-Old Postmenopausal Woman With Abdominal Distension\r 350
What are the next steps in the evaluation of this patient? 350
How is epithelial ovarian cancer staged? 351
What are the goals of surgery for ovarian cancer? 351
What does the patient do next? 353
Case Summary 354
References 354
53 - A 52-Year-Old Perimenopausal Woman With Irregular Bleeding\r 355
What are your next steps? 355
What is the likely diagnosis? 355
What is the incidence of cervical cancer? 355
What are some risk factors for the development of cervical cancer? 355
What are the main histologic subtypes of cervical cancer? 356
What is the pathogenesis for cervical cancer? 356
How is cervical cancer staged? 356
How is cervical cancer treated? 357
What is the recommended treatment of early-stage cervical cancer? 357
What is chemoradiation for cervical cancer? 358
What is a radical hysterectomy? 358
Case Summary 359
References 360
54 - A 58-Year-Old Woman With Postmenopausal Bleeding\r 361
What can cause postmenopausal bleeding? 361
With what symptoms does a patient with endometrial cancer usually present? 361
What are risk factors for endometrial cancer? 361
How do you classify endometrial cancer? 362
What is the initial evaluation of endometrial cancer? 362
What tests should be ordered for evaluation of endometrial cancer and presurgical planning? 363
What is the treatment for endometrial cancer? 363
Does the patient need additional treatment? 364
How common is recurrence, and what could be done if the cancer returns? 364
What does the patient do next? 364
Case Summary 365
References 365
55 - A 35-Year-Old Woman With a Family History of Ovarian Cancer\r 366
Which inherited genetic disorders carry an increased risk of ovarian cancer? 366
Who should be offered hereditary cancer risk assessment for hereditary breast and ovarian cancers?\r 366
What genetic testing should be offered to women with or at increased risk of ovarian/fallopiantube/primary peritoneal cancer?\r 366
What is the BRCA gene, and how common are mutations? 367
What is the lifetime risk of ovarian and breast cancer in a patient with BRCA mutation? 368
How should a risk-reducing BSO be performed? 369
Case Summary 370
References 370
56 - A 29-Year-Old Woman With Vaginal Bleeding\r 371
What is the differential diagnosis of vaginal bleeding? 371
What is the most likely diagnosis? 371
Who is at risk for developing GTN? 373
What are the next steps for diagnosis in our patient? 373
Where is GTN most likely to metastasize? 373
What laboratory or imaging studies should be ordered? 373
How is GTN staged? 373
How is GTN treated? 373
How should this patient be monitored? 374
Case Summary 375
References 375
57 - A 63-Year-Old With Known Ovarian Cancer and New-Onset Abdominal Symptoms\r 376
What are the next steps in this patient’s care? 376
What are options for treatment for recurrent epithelial ovarian cancer? 376
What chemotherapy is given at the time of recurrent ovarian cancer? 378
What options does the patient have now? 378
What is palliative care? 378
What is the patient’s diagnosis at this time? 379
What is the management of SBO in this patient? 379
What is hospice? 380
Case Summary 381
References 381
58 - A 57-Year-Old Woman With Pain on Sexual Intercourse\r 382
Why is it important to ask about and address sexual concerns among women? 382
When a woman has pain with intercourse, what do you need to know about her history? 382
What clues in the history might point toward vaginal atrophy? 383
What clues in the history might point toward a musculoskeletal origin of the pain? 383
In addition to evaluating the vaginal mucosa for atrophy and the pelvic muscles for pain, what other information should be gathered from this patient on pelvic exam?\r 383
What is the foreign body in this woman’s vagina, and how does that relate to her pain? 384
What treatment options exist for this woman’s vaginal mesh erosion? 384
What does the patient need to know prior to having the mesh removed? 385
What treatments can you offer the patient at this point? 385
Case Summary 386
References 386
59 - A 62-Year-Old Woman With Urinary Urgency and Incontinence\r 387
What are some causes of urinary frequency and urgency? 387
What initial workup should be performed at her first visit? 387
What is the patient’s likely diagnosis? 388
What are some first-line therapies to treat OAB? 388
What medical treatment can you offer the patient, and what is the mechanism of action? 389
What third-line treatments exist for the treatment of OAB? 389
Case Summary 392
References 392
60 - A 51-Year-Old With Frequent Urinary Tract Infections and Vaginal Dryness and Burning\r 393
What type of history is important to discuss with this patient and why? 393
What are physical signs of GSM? What physical exam is indicated to evaluate this patient? 393
How do you establish a diagnosis of recurrent UTI in this patient? 394
What are the common organisms isolated in recurrent UTIs? 395
What are the risk factors for recurrent UTIs in postmenopausal women? 395
How would you manage recurrent UTIs in the postmenopausal woman? 395
What measures can be taken to prevent recurrent UTIs? 396
What treatments can you offer the patient for her GSM? 396
Case Summary 398
References 398
61 - A 32-Year-Old Woman With Urinary Leakage on Exercise\r 399
What are risks factors for stress incontinence? 399
Why does SUI occur? 399
Is there any additional workup needed to make the diagnosis of SUI? 399
What treatment options are available to her? 400
Do you need to perform urodynamic testing prior to antiincontinence surgery? 401
What surgical options are available to treat stress incontinence? 402
What are the potential risks to mid-urethral slings?\r 402
What is the success rate of the operations to treat stress incontinence? 402
Case Summary 403
References 403
62 - A 43-Year-Old Woman With Pelvic Pain, Symptoms of Bladder Infections Despite Negative Urine Cultures\r 404
Why is it important to differentiate urinary frequency with pain from urinary urgency? 404
What is the relationship between IC/BPS and other pain disorders? 405
What are important elements of the physical exam if IC/BPS is suspected? 405
Are there any diagnostic tests to solidify the IC/BPS diagnosis? 405
What is important for the patient to know about IC/BPS? 406
Which treatments are most effective for IC/BPS? 406
What other therapies can be offered to this patient? 407
Case Summary 408
References 408
63 - A 65-Year-Old With Vaginal Bulge and Pelvic Pressure\r 409
What questions should you ask when obtaining the patient’s history? 409
What are some risks factors for POP? 409
What are key physical findings that you should look for? 409
What additional workup should be performed for this patient? 412
What are the risks of not intervening? 412
What nonsurgical options can you offer to the patient? 412
What surgical modalities are available for her? 412
How do you counsel her about the long-term durability of a POP surgery? 413
Case Summary 414
References 414
64 - A 63-Year-Old Woman With Fecal Incontinence\r 415
Why is it important to ask about fecal incontinence in women? 415
When a woman presents with FI, what should you ask about her history? 415
What is the role of an obstetric history when evaluating a woman with FI? 416
In addition to obstetrical injuries, what are other risk factors associated with FI? 416
What is the physiology of normal defecation? 416
What anatomic components are responsible for continence? 416
What physical exam findings are important for the evaluation of FI? 417
What studies are necessary for the workup of FI? 417
What are other initial treatment options that should be offered to the patient? 418
What other nonsurgical interventions are available to patients for FI? 418
When should surgical options for FI be offered to patients, and what common surgical options are available?\r 418
Case Summary 419
References 419
INDEX 420
A 420
B 422
C 422
D 424
E 425
F 426
G 427
H 428
I 429
K 431
L 431
M 432
N 433
O 433
P 434
Q 439
R 439
S 440
T 441
U 442
V 443
W 444
X 444
Z 444