Additional Information
Book Details
Abstract
Part of the in-depth and practical Pattern Recognition series, Practical Surgical Soft Tissue Pathology, 2nd Edition, helps you arrive at an accurate diagnosis by using a proven pattern-based approach. Leading diagnosticians guide you through the most common patterns seen in soft tissue pathology, applying appropriate immunohistochemistry and molecular testing, avoiding pitfalls, and making the best diagnosis. High-quality illustrations capture key morphologic patterns for a full range of common and rare tumor types, and a "visual index" at the beginning of the book directs you to the exact location of in-depth diagnostic guidance.
- A consistent chapter organization by histologic pattern considers soft tissue tumors the way you approach them in daily practice, helping you arrive at a quick and accurate diagnosis.
- A user-friendly design color-codes patterns to specific entities, and key points are summarized in tables and text boxes, so you can quickly and easily find what you are looking for.
- Sweeping content updates keep you at the forefront of recent findings regarding all major neoplastic and non-neoplastic diseases of the soft tissues.
- Improved pattern call-outs are now linked directly within the chapter, reinforcing the patterns for more efficient and complete understanding.
Table of Contents
| Section Title | Page | Action | Price |
|---|---|---|---|
| Front Cover | cover | ||
| Inside Front Cover | ifc1 | ||
| Half title page | i | ||
| Front Matter | iii | ||
| Practical Soft Tissue Pathology A Diagnostic Approach | iii | ||
| Copyright Page | iv | ||
| Dedication | v | ||
| Contributors | vii | ||
| Series Preface | ix | ||
| Preface to the First Edition | x | ||
| Preface | xi | ||
| Acknowledgment | xiii | ||
| Table Of Contents | xv | ||
| Pattern-Based Approach to Diagnosis | xvii | ||
| Pattern 1 Spindle Cell | xviii | ||
| Pattern 2 Epithelioid | xxiii | ||
| Pattern 3 Pleomorphic | xxvi | ||
| Pattern 4 Round Cell | xxviii | ||
| Pattern 5 Biphasic or Mixed | xxx | ||
| Pattern 6 Myxoid | xxxii | ||
| 1 Introduction: Tumor Classification and Immunohistochemistry | 1 | ||
| Tumor Classification | 1 | ||
| Immunohistochemistry | 1 | ||
| Intermediate Filament Proteins | 2 | ||
| Other Myogenic Markers | 3 | ||
| Endothelial Markers | 3 | ||
| Schwannian Markers | 4 | ||
| Other Diagnostic Markers | 4 | ||
| Protein Correlates of Genetic Alterations | 4 | ||
| Novel Markers Discovered by Gene Expression Profiling | 5 | ||
| References | 6 | ||
| 2 Biologic Potential, Grading, Staging, and Reporting of Sarcomas | 9 | ||
| Biologic Potential | 9 | ||
| Sarcoma Grading | 9 | ||
| Sarcoma Staging | 12 | ||
| Surgical Margins | 13 | ||
| References | 14 | ||
| 3 Spindle Cell Tumors of Adults | 15 | ||
| General Concepts | 16 | ||
| Approach to the Diagnosis of Spindle Cell Tumors of Soft Tissue | 16 | ||
| Frequency | 17 | ||
| Clinical Context | 17 | ||
| Histologic Parameters | 17 | ||
| Ancillary Techniques | 18 | ||
| Nonmesenchymal Neoplasms With Spindle Cell Cytomorphology | 18 | ||
| Spindle Cell Carcinoma | 18 | ||
| Spindle Cell Melanoma and Variants | 18 | ||
| Malignant Mesothelioma | 19 | ||
| Nodular Fasciitis and Similar Pseudosarcomatous Myofibroblastic Lesions | 20 | ||
| Nodular Fasciitis | 20 | ||
| Clinical Features | 20 | ||
| Pathologic Features | 20 | ||
| Immunohistochemistry | 25 | ||
| Molecular Genetics | 25 | ||
| Differential Diagnosis | 25 | ||
| Prognosis and Treatment | 25 | ||
| Pseudosarcomatous Myofibroblastic Proliferation | 25 | ||
| Clinical Features | 26 | ||
| Pathologic Features | 26 | ||
| Immunohistochemistry | 26 | ||
| Molecular Genetics | 26 | ||
| Differential Diagnosis | 26 | ||
| Prognosis and Treatment | 27 | ||
| Mycobacterial Spindle Cell Pseudotumor | 27 | ||
| Myofibroma and Myopericytoma | 27 | ||
| Clinical Features | 27 | ||
| Pathologic Features | 27 | ||
| Immunohistochemistry | 29 | ||
| Molecular Genetics | 29 | ||
| Differential Diagnosis | 29 | ||
| Prognosis and Treatment | 29 | ||
| Phosphaturic Mesenchymal Tumor | 30 | ||
| Clinical Features | 30 | ||
| Pathologic Features | 30 | ||
| Immunohistochemistry | 30 | ||
| Molecular Genetics | 30 | ||
| Differential Diagnosis | 31 | ||
| Prognosis and Treatment | 31 | ||
| Myofibroblastoma and Variants | 31 | ||
| Mammary-Type Myofibroblastoma | 31 | ||
| Intranodal Palisaded Myofibroblastoma | 32 | ||
| Fibroma | 33 | ||
| Fibroma of Tendon Sheath | 33 | ||
| Clinical Features | 33 | ||
| Pathologic Features | 33 | ||
| Immunohistochemistry | 33 | ||
| Molecular Genetics | 33 | ||
| Differential Diagnosis | 33 | ||
| Prognosis and Treatment | 34 | ||
| Desmoplastic Fibroblastoma (Collagenous Fibroma) | 34 | ||
| Clinical Features | 34 | ||
| Pathologic Features | 34 | ||
| Immunohistochemistry | 34 | ||
| Molecular Genetics | 34 | ||
| Differential Diagnosis | 34 | ||
| Prognosis and Treatment | 35 | ||
| Nuchal-Type Fibroma | 35 | ||
| Clinical Features | 35 | ||
| Pathologic Features | 35 | ||
| Immunohistochemistry | 36 | ||
| Differential Diagnosis | 36 | ||
| Prognosis and Treatment | 36 | ||
| Elastofibroma | 36 | ||
| Clinical Features | 36 | ||
| Pathologic Features | 36 | ||
| Immunohistochemistry | 37 | ||
| Differential Diagnosis | 37 | ||
| Prognosis and Treatment | 37 | ||
| Calcifying Fibrous Tumor | 37 | ||
| Angiofibroma of Soft Tissue | 37 | ||
| Clinical Features | 37 | ||
| Pathologic Features | 37 | ||
| Immunohistochemistry | 38 | ||
| Molecular Genetics | 38 | ||
| Differential Diagnosis | 38 | ||
| 4 Pediatric Spindle Cell Tumors | 101 | ||
| Fibroblastic-Myofibroblastic Tumors | 101 | ||
| Benign Tumors That Mimic Sarcomas | 102 | ||
| Nodular Fasciitis | 102 | ||
| Clinical Features | 102 | ||
| Pathologic Features | 102 | ||
| Immunohistochemistry | 102 | ||
| Molecular Genetics | 103 | ||
| Differential Diagnosis | 103 | ||
| Prognosis and Treatment | 103 | ||
| Cranial Fasciitis | 103 | ||
| 5 Tumors With Myxoid Stroma | 135 | ||
| Ganglion Cyst | 135 | ||
| Clinical Features | 135 | ||
| Pathologic Features | 136 | ||
| Differential Diagnosis | 136 | ||
| Prognosis and Treatment | 137 | ||
| Intramuscular/Cellular Myxoma | 137 | ||
| Clinical Features | 137 | ||
| Pathologic Features | 137 | ||
| Immunohistochemistry | 137 | ||
| Molecular Genetics | 137 | ||
| Differential Diagnosis | 137 | ||
| Prognosis and Treatment | 138 | ||
| Juxtaarticular Myxoma | 138 | ||
| Clinical Features | 138 | ||
| Pathologic Features | 138 | ||
| Immunohistochemistry | 138 | ||
| Molecular Genetics | 138 | ||
| Differential Diagnosis | 138 | ||
| Prognosis and Treatment | 139 | ||
| Dermal Nerve Sheath Myxoma | 139 | ||
| Clinical Features | 139 | ||
| Pathologic Features | 139 | ||
| 6 Epithelioid and Epithelial-Like Tumors | 165 | ||
| Approach to the Diagnosis of Epithelioid Tumors of Soft Tissue | 165 | ||
| Clinical Presentation | 165 | ||
| Microscopic Examination | 167 | ||
| Immunohistochemistry | 168 | ||
| Cytogenetics | 168 | ||
| Epithelioid Hemangioma | 168 | ||
| Clinical Features | 168 | ||
| Pathologic Features | 169 | ||
| Immunohistochemistry | 170 | ||
| Molecular Genetics | 170 | ||
| Differential Diagnosis | 170 | ||
| Prognosis and Treatment | 171 | ||
| Glomus Tumor | 171 | ||
| Clinical Features | 171 | ||
| Pathologic Features | 171 | ||
| Immunohistochemistry | 172 | ||
| Molecular Genetics | 173 | ||
| Differential Diagnosis | 173 | ||
| Prognosis and Treatment | 173 | ||
| Myoepithelioma/Mixed Tumor/Myoepithelial Carcinoma of Soft Tissue | 173 | ||
| Clinical Features | 174 | ||
| Pathologic Features | 174 | ||
| Immunohistochemistry | 174 | ||
| Molecular Genetics | 176 | ||
| Differential Diagnosis | 176 | ||
| Prognosis and Treatment | 177 | ||
| PEComa of Soft Tissue | 177 | ||
| Clinical Features | 177 | ||
| 7 Pleomorphic Sarcomas | 209 | ||
| Atypical Fibroxanthoma | 210 | ||
| Clinical Features | 210 | ||
| Pathologic Features | 210 | ||
| Immunohistochemistry | 210 | ||
| Molecular Genetics | 212 | ||
| Differential Diagnosis | 212 | ||
| Prognosis and Treatment | 212 | ||
| Undifferentiated Pleomorphic Sarcoma | 212 | ||
| Clinical Features | 213 | ||
| Pathologic Features | 213 | ||
| Immunohistochemistry | 213 | ||
| Molecular Genetics | 214 | ||
| Differential Diagnosis | 214 | ||
| Prognosis and Treatment | 214 | ||
| Pleomorphic Hyalinizing Angiectatic Tumor | 216 | ||
| Clinical Features | 216 | ||
| Pathologic Features | 216 | ||
| Immunohistochemistry | 216 | ||
| Molecular Genetics | 216 | ||
| Differential Diagnosis | 217 | ||
| Prognosis and Treatment | 217 | ||
| Myxoinflammatory Fibroblastic Sarcoma | 217 | ||
| 8 Round Cell Tumors | 233 | ||
| The Role of Immunohistochemistry and Molecular Genetics | 233 | ||
| How Should Small Round Cell Sarcoma Samples Be Handled? | 234 | ||
| Should Molecular Techniques to Detect Translocations Always Be Performed? | 234 | ||
| Ewing Sarcoma | 235 | ||
| Clinical Features | 236 | ||
| Pathologic Features | 236 | ||
| Immunohistochemistry | 237 | ||
| Molecular Genetics | 238 | ||
| Differential Diagnosis | 238 | ||
| Prognosis and Treatment | 239 | ||
| Alveolar Rhabdomyosarcoma | 239 | ||
| Clinical Features | 239 | ||
| Pathologic Features | 240 | ||
| Immunohistochemistry | 240 | ||
| Molecular Genetics | 241 | ||
| Differential Diagnosis | 242 | ||
| Prognosis and Treatment | 242 | ||
| Embryonal Rhabdomyosarcoma | 242 | ||
| Clinical Features | 242 | ||
| Pathologic Features | 242 | ||
| Immunohistochemistry | 243 | ||
| Molecular Genetics | 243 | ||
| Differential Diagnosis | 243 | ||
| Prognosis and Treatment | 243 | ||
| “Round Cell” Liposarcoma | 243 | ||
| Desmoplastic Small Round Cell Tumor | 243 | ||
| Clinical Features | 243 | ||
| 9 Biphasic Tumors and Tumors With Mixed Patterns | 249 | ||
| Biphasic Synovial Sarcoma | 249 | ||
| Clinical Features | 249 | ||
| Pathologic Features | 249 | ||
| Immunohistochemistry | 250 | ||
| Molecular Genetics | 250 | ||
| Differential Diagnosis | 251 | ||
| Prognosis and Treatment | 252 | ||
| Mixed Tumor/Myoepithelioma/ Myoepithelial Carcinoma | 252 | ||
| Clinical Features | 252 | ||
| Pathologic Features | 252 | ||
| Immunohistochemistry | 252 | ||
| Molecular Genetics | 252 | ||
| Differential Diagnosis | 253 | ||
| Prognosis and Treatment | 254 | ||
| Malignant Peripheral Nerve Sheath Tumor With Divergent (Heterologous) Differentiation (Including Glandular Type) | 254 | ||
| Clinical Features | 254 | ||
| Pathologic Features | 254 | ||
| Immunohistochemistry | 255 | ||
| Molecular Genetics | 255 | ||
| Differential Diagnosis | 255 | ||
| Prognosis and Treatment | 256 | ||
| Ectopic Hamartomatous Thymoma | 256 | ||
| Clinical Features | 256 | ||
| Pathologic Features | 256 | ||
| Immunohistochemistry | 257 | ||
| Differential Diagnosis | 257 | ||
| Prognosis and Treatment | 257 | ||
| Gastrointestinal Stromal Tumor, Mixed Type | 258 | ||
| Clinical Features | 258 | ||
| Pathologic Features | 258 | ||
| Immunohistochemistry | 258 | ||
| Molecular Genetics | 258 | ||
| 10 Soft Tissue Tumors With Prominent Inflammatory Cells | 269 | ||
| Inflammatory Myofibroblastic Tumor | 269 | ||
| Clinical Features | 269 | ||
| Pathologic Features | 270 | ||
| Immunohistochemistry | 270 | ||
| Molecular Genetics | 270 | ||
| Differential Diagnosis | 270 | ||
| Prognosis and Treatment | 273 | ||
| Inflammatory Leiomyosarcoma | 273 | ||
| Histiocytic and Dendritic Cell Tumors | 273 | ||
| Follicular Dendritic Cell Sarcoma | 274 | ||
| Clinical Features | 274 | ||
| Pathologic Features | 274 | ||
| Immunohistochemistry | 275 | ||
| Molecular Genetics | 275 | ||
| Differential Diagnosis | 275 | ||
| Prognosis and Treatment | 277 | ||
| Fibroblastic Reticular Cell Sarcoma | 277 | ||
| Interdigitating Dendritic Cell Sarcoma | 277 | ||
| Clinical Features | 277 | ||
| Pathologic Features | 277 | ||
| Immunohistochemistry | 279 | ||
| Differential Diagnosis | 280 | ||
| Prognosis and Treatment | 280 | ||
| Langerhans Cell Histiocytosis and Langerhans Cell Sarcoma | 280 | ||
| Clinical Features | 280 | ||
| Pathologic Features | 280 | ||
| Immunohistochemistry | 280 | ||
| Molecular Genetics | 281 | ||
| Differential Diagnosis | 281 | ||
| Prognosis and Treatment | 281 | ||
| Indeterminate Cell Histiocytosis | 282 | ||
| Extranodal Rosai-Dorfman Disease | 283 | ||
| Histiocytic Sarcoma | 283 | ||
| Clinical Features | 284 | ||
| Pathologic Features | 284 | ||
| Immunohistochemistry | 284 | ||
| Molecular Genetics | 284 | ||
| Differential Diagnosis | 284 | ||
| Prognosis and Treatment | 285 | ||
| Angiomatoid Fibrous Histiocytoma | 285 | ||
| Clinical Features | 285 | ||
| Pathologic Features | 285 | ||
| Immunohistochemistry | 285 | ||
| Molecular Genetics | 285 | ||
| Differential Diagnosis | 285 | ||
| Prognosis and Treatment | 286 | ||
| Myxoinflammatory Fibroblastic Sarcoma | 286 | ||
| Well-Differentiated Inflammatory Liposarcoma | 286 | ||
| Inflammatory Malignant Fibrous Histiocytoma | 288 | ||
| Mass-Forming Idiopathic Fibroinflammatory Disorders | 289 | ||
| Sclerosing Mesenteritis | 289 | ||
| Idiopathic Retroperitoneal Fibrosis | 289 | ||
| Immunoglobulin G4–Related Disease | 290 | ||
| References | 293 | ||
| 11 Giant Cell–Rich Tumors | 297 | ||
| Tenosynovial Giant Cell Tumors | 298 | ||
| Giant Cell Tumor of Tendon Sheath (Localized-Type Tenosynovial Giant Cell Tumor) | 298 | ||
| Clinical Features | 298 | ||
| Pathologic Features | 298 | ||
| Immunohistochemistry | 298 | ||
| Molecular Genetics | 299 | ||
| Differential Diagnosis | 300 | ||
| Prognosis and Treatment | 300 | ||
| Diffuse-Type (Tenosynovial) Giant Cell Tumor | 301 | ||
| Clinical Features | 301 | ||
| Pathologic Features | 301 | ||
| Immunohistochemistry | 302 | ||
| 12 Adipocytic Tumors | 311 | ||
| Lipoma | 312 | ||
| Clinical Features | 312 | ||
| Pathologic Features | 312 | ||
| Immunohistochemistry | 312 | ||
| Molecular Genetics | 312 | ||
| Differential Diagnosis | 312 | ||
| Prognosis and Treatment | 313 | ||
| Lipofibromatosis | 313 | ||
| Clinical Features | 313 | ||
| 13 Vascular Tumors | 341 | ||
| Immunohistochemistry | 341 | ||
| Classification of Vascular Tumors | 342 | ||
| Vasoformative Pattern | 344 | ||
| Papillary Endothelial Hyperplasia (Masson Tumor) | 344 | ||
| Clinical Features | 344 | ||
| Pathologic Features | 344 | ||
| Differential Diagnosis | 344 | ||
| 14 Cartilaginous and Osseous Soft Tissue Lesions | 391 | ||
| Myositis Ossificans and Heterotopic Ossification | 391 | ||
| Clinical Features | 391 | ||
| 15 Cutaneous Mesenchymal Tumors | 403 | ||
| Spindle Cell Tumors | 405 | ||
| Benign Fibrous Histiocytoma (Dermatofibroma) and Variants | 405 | ||
| Clinical Features | 405 | ||
| Pathologic Features | 407 | ||
| Immunohistochemistry | 409 | ||
| Differential Diagnosis | 409 | ||
| Prognosis and Treatment | 410 | ||
| Cellular Benign Fibrous Histiocytoma | 410 | ||
| Aneurysmal Benign Fibrous Histiocytoma | 411 | ||
| Atypical (Pseudosarcomatous) Fibrous Histiocytoma | 411 | ||
| Dermatomyofibroma | 412 | ||
| 16 Mesenchymal Tumors of the Gastrointestinal Tract | 459 | ||
| Gastrointestinal Stromal Tumor | 460 | ||
| Clinical Features | 460 | ||
| Pathologic Features | 461 | ||
| Immunohistochemistry | 465 | ||
| Molecular Genetics | 466 | ||
| Differential Diagnosis | 468 | ||
| Prognosis and Treatment | 469 | ||
| Leiomyoma | 471 | ||
| Clinical Features | 471 | ||
| Pathologic Features | 472 | ||
| Immunohistochemistry | 472 | ||
| Molecular Genetics | 472 | ||
| 17 Lower Genital Soft Tissue Tumors | 499 | ||
| General Approach to Soft Tissue Lesions of the Lower Genital Tract | 499 | ||
| Deep (Aggressive) Angiomyxoma | 499 | ||
| Clinical Features | 499 | ||
| Pathologic Features | 499 | ||
| Immunohistochemistry | 500 | ||
| Molecular Genetics | 500 | ||
| Differential Diagnosis | 500 | ||
| Prognosis and Treatment | 500 | ||
| Fibroepithelial Stromal Polyp | 501 | ||
| Clinical Features | 501 | ||
| Pathologic Features | 501 | ||
| Immunohistochemistry | 501 | ||
| Differential Diagnosis | 501 | ||
| Prognosis and Treatment | 502 | ||
| Angiomyofibroblastoma | 502 | ||
| Clinical Features | 502 | ||
| Pathologic Features | 502 | ||
| Immunohistochemistry | 502 | ||
| Molecular Genetics | 502 | ||
| Differential Diagnosis | 503 | ||
| Prognosis and Treatment | 504 | ||
| Cellular Angiofibroma | 504 | ||
| Clinical Features | 504 | ||
| Pathologic Features | 504 | ||
| Immunohistochemistry | 504 | ||
| Molecular Genetics | 504 | ||
| Differential Diagnosis | 504 | ||
| 18 Applications of Molecular Testing to Differential Diagnosis | 513 | ||
| Keywords | 513 | ||
| Genetic Classification of Sarcomas | 513 | ||
| Approaches to Molecular Diagnostics | 514 | ||
| The Paradigm of Ewing Sarcoma | 514 | ||
| Techniques | 518 | ||
| Chromosomal Karyotype | 518 | ||
| Fluorescence In Situ Hybridization | 519 | ||
| Reverse Transcription Polymerase Chain Reaction | 519 | ||
| Next-Generation Sequencing Molecular Assays. | 523 | ||
| Molecular Features of Particular Entities | 524 | ||
| Soft Tissue Sarcomas With Complex Cytogenetic Features | 525 | ||
| Soft Tissue Sarcomas With Simple Cytogenetic Features | 525 | ||
| Alveolar Soft Part Sarcoma | 525 | ||
| Angiomatoid Fibrous Histiocytoma | 526 | ||
| Angiosarcoma | 526 | ||
| Benign Fibrous Histiocytoma (Dermatofibroma) | 526 | ||
| Biphenotypic Sinonasal Sarcoma | 526 | ||
| Clear Cell Sarcoma | 526 | ||
| Dermatofibrosarcoma Protuberans | 529 | ||
| Desmoid-Type Fibromatosis | 530 | ||
| Desmoplastic Small Round Cell Tumor | 531 | ||
| Endometrial Stromal Sarcoma | 533 | ||
| Epithelioid Hemangioendothelioma | 533 | ||
| Ewing Sarcoma | 533 | ||
| Ewing-Like Tumors With Alternative Fusion Transcripts | 533 | ||
| Extraskeletal Myxoid Chondrosarcoma | 533 | ||
| Glomus Tumors | 534 | ||
| Gastrointestinal Stromal Tumor | 534 | ||
| Infantile Fibrosarcoma | 535 | ||
| Inflammatory Myofibroblastic Tumor | 536 | ||
| Leiomyoma | 536 | ||
| Lipoma Variants (Benign Adipocytic Tumors) | 539 | ||
| Conventional Lipoma. | 539 | ||
| Other Lipoma Variants. | 539 | ||
| Liposarcoma | 540 | ||
| Myxoid Liposarcoma. | 540 | ||
| Well-Differentiated and Dedifferentiated Liposarcoma. | 540 | ||
| Lipofibromatosis-Like Neural Tumors | 540 | ||
| Low-Grade Fibromyxoid Sarcoma | 540 | ||
| Mesenchymal Chondrosarcoma | 541 | ||
| Myoepithelial Tumors of Soft Tissue | 541 | ||
| Myxoinflammatory Fibroblastic Sarcoma and Hemosiderotic Fibrolipomatous Tumor | 542 | ||
| Myxomas | 542 | ||
| Neurofibroma | 542 | ||
| Nodular Fasciitis | 542 | ||
| Ossifying Fibromyxoid Tumor | 543 | ||
| Pericytoma With t(7;12) | 543 | ||
| Pseudomyogenic Hemangioendothelioma | 543 | ||
| Rhabdomyosarcoma | 543 | ||
| Sclerosing Epithelioid Fibrosarcoma | 544 | ||
| Schwannoma | 544 | ||
| Synovial Sarcoma | 544 | ||
| Solitary Fibrous Tumor | 544 | ||
| Tenosynovial Giant Cell Tumor | 544 | ||
| Practical Applications of Molecular Diagnostic Testing | 545 | ||
| Desmoplastic Small Round Cell Tumor Versus Ewing Sarcoma | 545 | ||
| Clear Cell Sarcoma Versus Metastatic Melanoma | 545 | ||
| Well-Differentiated Liposarcoma With Myxoid Stroma Versus Myxoid Liposarcoma | 546 | ||
| Solid Alveolar Rhabdomyosarcoma Versus Embryonal Rhabdomyosarcoma | 547 | ||
| Extraskeletal Myxoid Chondrosarcoma Versus Soft Tissue Myoepithelioma/Myoepithelial Carcinoma | 547 | ||
| Small Cell (Poorly Differentiated) Synovial Sarcoma Versus Ewing Sarcoma | 548 | ||
| Gastrointestinal Stromal Tumor With Unusual Features | 548 | ||
| Significance of Detecting an EWSR1 Gene Rearrangement by Fluorescence In Situ Hybridization | 549 | ||
| Conclusions | 549 | ||
| References | 551 | ||
| Index | 557 | ||
| A | 557 | ||
| B | 559 | ||
| C | 559 | ||
| D | 561 | ||
| E | 563 | ||
| F | 564 | ||
| G | 566 | ||
| H | 568 | ||
| I | 569 | ||
| J | 570 | ||
| K | 570 | ||
| L | 570 | ||
| M | 572 | ||
| N | 575 | ||
| O | 576 | ||
| P | 576 | ||
| R | 578 | ||
| S | 579 | ||
| T | 583 | ||
| U | 583 | ||
| V | 583 | ||
| W | 584 | ||
| X | 584 | ||
| Inside Back Cover | ibc1 |