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Interventional Heart Failure, An Issue of Interventional Cardiology Clinics, E-Book

Interventional Heart Failure, An Issue of Interventional Cardiology Clinics, E-Book

Srihari S. Naidu

(2017)

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Book Details

Abstract

This issue of Interventional Cardiology Clinics, guest edited by Dr. Srihari S. Naidu, will discuss Interventional techniques for Heart Failure. Subjects covered in the articles include, but are not limited to: Invasive Hemodynamics of Myocardial Disease: Systolic and Diastolic Dysfunction; Invasive Hemodynamics of Pericardial Disease: Constriction and Tamponade; Invasive Hemodynamics of Pulmonary Disease and the Right Ventricle; TAVR and MitraClip to Reverse Heart Failure; Mechanical Circulatory Support in Acute Decompensated Heart Failure and Shock; Adult Congenital Interventions in Heart Failure; Future Directions in Device Treatment of Heart Failure; and Prioritizing and Combining Interventional Therapies for Heart Failure, among others.

Table of Contents

Section Title Page Action Price
Front Cover Cover
INTERVENTIONAL CARDIOLOGY CLINICS i
Copyright ii
CONTRIBUTORS iii
EDITOR-IN-CHIEF iii
EDITOR iii
AUTHORS iii
CONTENTS vii
Preface: Operationalizing Interventional Heart Failure: Adding Substance to the Concept\r vii
I - Hemodynamics of Heart Failure Disease States vii
Invasive Hemodynamics of Myocardial Disease: Systolic and Diastolic Dysfunction (and Hypertrophic Obstructive Cardiomyopath ...\r vii
Invasive Hemodynamics of Pericardial Disease\r vii
Invasive Hemodynamics of Valvular Heart Disease\r vii
Invasive Hemodynamics of Pulmonary Disease and the Right Ventricle\r viii
Invasive Hemodynamics of Adult Congenital Heart Disease: From Shunts to Coarctation\r viii
Hemodynamics of Cardiogenic Shock359 viii
II - Interventional Treatments to Improve/Reverse Heart Failure viii
Transcatheter Aortic Valve Replacement and MitraClip to Reverse Heart Failure\r viii
Mechanical Circulatory Support in Acute Decompensated Heart Failure and Shock\r ix
Multivessel Revascularization in Shock and High-Risk Percutaneous Coronary Intervention\r ix
Cardiac Resynchronization Therapy for Heart Failure\r ix
Adult Congenital Interventions in Heart Failure\r ix
Alcohol Septal Ablation to Reduce Heart Failure\r ix
Renal Denervation to Modify Hypertension and the Heart Failure State\r x
III - Interventional Heart Failure\r x
Prioritizing and Combining Therapies for Heart Failure in the Era of Mechanical Support Devices\r x
Integrating Interventional Cardiology and Heart Failure Management for Cardiogenic Shock\r x
INTERVENTIONAL HEART FAILURE\r xi
FORTHCOMING ISSUES xi
RECENT ISSUES xi
PREFACE\r xiii
Operationalizing Interventional Heart Failure: Adding Substance to the Concept xiii
Invasive Hemodynamics of Myocardial Disease 297
KEY POINTS 297
INTRODUCTION 297
ASSESSMENT OF CARDIAC CONTRACTILITY 297
THE PRESSURE-VOLUME LOOP AND LEFT VENTRICULAR FUNCTION 298
CONTRACTILITY, MYOCARDIAL WORK, AND CARDIAC POWER OUTPUT 298
DIASTOLE 301
PRELOAD 302
AFTERLOAD 302
RIGHT HEART DYSFUNCTION 302
HEART FAILURE WITH PRESERVED EJECTION FRACTION 302
HEMODYNAMIC PRESSURE WAVEFORM EXAMPLES OF MYOCARDIAL DYSFUNCTION 303
Pulsus Alternans 303
HYPERTROPHIC OBSTRUCTIVE CARDIOMYOPATHY 304
SUMMARY 306
REFERENCES 306
Invasive Hemodynamics of Pericardial Disease 309
KEY POINTS 309
Approach to Patients 309
CONSTRICTIVE PERICARDITIS 310
Pathophysiology 310
Invasive Hemodynamic Assessment 311
CARDIAC TAMPONADE 313
Pathophysiology 313
INVASIVE HEMODYNAMICS 315
REFERENCES 317
Invasive Hemodynamics of Valvular Heart Disease 319
KEY POINTS 319
INTRODUCTION 319
General Principles of Invasive Hemodynamic Assessment of Valvular Heart Disease 319
Valvular stenosis 319
AORTIC STENOSIS 320
Indication 320
Technique 320
Hemodynamic findings and interpretation 321
Challenges in hemodynamic assessment 321
Carabello sign 321
Aortic pressure 322
Low gradient aortic stenosis 322
MITRAL STENOSIS 322
Indication 322
Technique 323
Hemodynamic Findings and Interpretation 323
Pitfalls 323
Atrial fibrillation 323
Wedge pressure versus left atrial pressure measurement 323
Limitations of the Gorlin formula 323
Valvular Regurgitation 324
MITRAL REGURGITATION 325
Indication 325
Technique 325
Hemodynamic Findings and Interpretation 325
Pitfalls 326
AORTIC REGURGITATION 326
Indication 326
Technique 326
Hemodynamic Findings and Interpretation 326
SUMMARY 327
REFERENCES 327
Invasive Hemodynamics of Pulmonary Disease and the Right Ventricle 329
KEY POINTS 329
INTRODUCTION 329
HISTORY OF PULMONARY HYPERTENSION AND THE RIGHT VENTRICLE 329
ANATOMY OF THE RIGHT VENTRICLE AND PULMONARY CIRCULATION 330
PULMONARY HYPERTENSION 331
RIGHT HEART CATHETERIZATION 333
EXPECTED RIGHT HEART CATHETERIZATION FINDINGS BASED ON PULMONARY HYPERTENSION GROUP 335
PRESSURE–VOLUME LOOPS AND HEMODYNAMICS SEEN IN PULMONARY HYPERTENSION ON THE RIGHT VENTRICLE 336
TOOLS USED TO ASSESS RIGHT VENTRICULAR AND LEFT VENTRICULAR PRESSURE–VOLUME LOOPS 339
REVERSIBILITY STUDY IN PULMONARY HYPERTENSION 340
SUMMARY 341
REFERENCES 341
Invasive Hemodynamics of Adult Congenital Heart Disease 345
KEY POINTS 345
INTRODUCTION 345
BIVENTRICULAR CONGENITAL HEART DISEASE 346
Shunting Lesions 346
Atrial septal defects 347
Ventricular septal defects 347
Patent ductus arteriosus 347
Repaired Congenital Heart Disease 347
D-transposition of the great arteries 347
Tetralogy of Fallot and truncus arteriosus 349
Left-Sided Obstructive Lesions 349
Mitral stenosis 349
Valvar aortic stenosis 349
Valve area 350
Left ventricular outflow tract obstruction 350
Supravalvar aortic stenosis 350
Coarctation of the aorta 350
UNIVENTRICULAR CONGENITAL HEART DISEASE 350
Partial/Shunt Palliated 351
Palliative pulmonary artery banding surgery 351
Systemic artery to pulmonary artery shunts 351
Superior (partial) cavopulmonary shunt 352
Fully Palliated (Fontan) 352
Patent Fontan fenestration 354
Fontan baffle leak 354
Venovenous collaterals 355
Pulmonary arteriovenous malformations 355
Aortopulmonary collaterals 356
SUMMARY 357
REFERENCES 357
Hemodynamics of Cardiogenic Shock 359
KEY POINTS 359
INTRODUCTION 359
DEFINITIONS 359
ETIOLOGY 360
DIAGNOSIS AND EVALUATION OF CARDIOGENIC SHOCK PATIENTS 361
PATHOPHYSIOLOGY AND HEMODYNAMICS 362
Decreased Contractility 362
Autonomic Response to Decreased Contractility 363
Inflammatory Response 364
Remodeling 364
Right Ventricular Failure Involvement in Cardiogenic Shock 365
MECHANICAL COMPLICATIONS OF ACUTE MYOCARDIAL INFARCT PRESENTING AS CARDIOGENIC SHOCK 365
RISK STRATIFICATION AND PROGNOSIS 365
MANAGEMENT OF CARDIOGENIC SHOCK 366
SUMMARY 368
REFERENCES 369
Transcatheter Aortic Valve Replacement and MitraClip to Reverse Heart Failure 373
KEY POINTS 373
INTRODUCTION 373
TRANSCATHETER AORTIC VALVE REPLACEMENT IN PATIENTS WITH HEART FAILURE 373
Outcomes of Transcatheter Aortic Valve Replacement in Patients with Heart Failure 374
Left Ventricular Ejection Fraction Recovery After Transcatheter Aortic Valve Replacement: Determinants 376
MITRACLIP IN PATIENTS WITH SEVERE HEART FAILURE 377
MitraClip in Degenerative or Primary Mitral Regurgitation 378
MitraClip in Functional or Secondary Mitral Regurgitation 380
MitraClip Effect on Remodeling 383
SUMMARY 384
REFERENCES 385
Mechanical Circulatory Support in Acute Decompensated Heart Failure and Shock 387
KEY POINTS 387
INTRODUCTION 387
INTRA-AORTIC BALLOON PUMP 387
Introduction and Components 387
Hemodynamic Effects 387
Technical Considerations and Contraindications 389
Management 389
Clinical Data and Guidelines for Intra-aortic Balloon Pump 391
LEFT ATRIAL TO AORTA ASSIST DEVICE: TANDEM HEART 391
Introduction and Components 391
Inflow and outflow cannulae 392
Centrifugal pump 392
Console 392
Hemodynamic Effects 392
Technical Considerations and Contraindications 392
Management 393
Clinical Data and Guidelines for TandemHeart 394
LEFT VENTRICULAR TO AORTA ASSIST DEVICES: IMPELLA 394
Introduction and Components 394
Hemodynamic Effects 395
Technical Considerations and Contraindications 395
Management 395
Position monitoring 396
Suction alarm 396
Hemolysis 396
Heparin-induced thrombocytopenia 396
Weaning 396
Clinical Data and Guidelines: Impella 396
Impella RP 397
EXTRACORPOREAL MEMBRANE OXYGENATION 397
Introduction and Components 397
Hemodynamic Effects 399
Technical Considerations and Contraindications 399
Management 399
CLINICAL DATA AND GUIDELINES: EXTRACORPOREAL MEMBRANE OXYGENATION 400
PERCUTANEOUS HEART PUMP 400
SUMMARY 402
REFERENCES 404
Multivessel Revascularization in Shock and High-Risk Percutaneous Coronary Intervention 407
KEY POINTS 407
MULTIVESSEL CORONARY ARTERY DISEASE AND CARDIOGENIC SHOCK 407
CARDIOGENIC SHOCK 408
Patients with Multivessel Disease Presenting with Acute Coronary Syndrome 408
Patients with Multivessel Disease Presenting with Stable Coronary Artery Disease 411
SUMMARY 414
REFERENCES 414
Cardiac Resynchronization Therapy for Heart Failure 417
KEY POINTS 417
INTRODUCTION 417
SEQUELAE OF CONDUCTION ABNORMALITIES AND DYSSYNCHRONY IN HEART FAILURE 417
FAVORABLE EFFECTS OF RESYNCHRONIZATION 418
PACING IN HEART FAILURE 418
OPTIMAL HEART FAILURE PATIENT SELECTION FOR RESYNCHRONIZATION 418
CARDIAC RESYNCHRONIZATION THERAPY IN HEART FAILURE WITH SPECIFIC CONDITIONS 419
Cardiac Resynchronization Therapy in Atrial Fibrillation 419
Cardiac Resynchronization Therapy in Patients Who are Pacemaker-Dependent 419
Cardiac Resynchronization Therapy in Patients with Mitral Regurgitation 419
Cardiac Resynchronization Therapy in Patients with Right Ventricular Dysfunction 420
OPTIMIZATION OF CARDIAC RESYNCHRONIZATION THERAPY 420
TIMING OF RESPONSE TO RESYNCHRONIZATION 420
PREDICTORS OF RESPONSE TO RESYNCHRONIZATION 420
DEFIBRILLATOR BENEFITS 421
COMPLICATIONS OF CARDIAC RESYNCHRONIZATION THERAPY DEVICE 421
COST-EFFECTIVENESS OF CARDIAC RESYNCHRONIZATION THERAPY DEVICE IN HEART FAILURE 422
CURRENT INDICATIONS OF CARDIAC RESYNCHRONIZATION THERAPY IN HEART FAILURE 422
Class I 422
Class IIa 422
Class IIb 422
Class III: Contraindications for Cardiac Resynchronization Therapy 422
FUTURE DIRECTIONS OF CARDIAC RESYNCHRONIZATION THERAPY IN HEART FAILURE 423
SUMMARY 423
REFERENCES 423
Adult Congenital Interventions in Heart Failure 427
KEY POINTS 427
INTRODUCTION 427
PREPROCEDURAL ASSESSMENT 428
DEFECT-SPECIFIC CONDITIONS 429
Shunt Lesions 429
Atrial septal defects 429
Ventricular septal defect 430
Patent ductus arteriosus 431
Coronary artery fistula 432
Aortopulmonary collaterals 434
Congenital Valvular Defects 434
Pulmonary valve stenosis 434
Percutaneous pulmonary valve implantation 435
Aortic stenosis 436
Obstructive Vascular Lesions 437
Coarctation of aorta 437
Branch pulmonary artery stenosis 438
Complex Congenital Heart Disease 439
D-transposition of the great vessels 439
Post-Fontan 439
Miscellaneous conditions 440
SUMMARY 441
REFERENCES 441
Alcohol Septal Ablation to Reduce Heart Failure 445
KEY POINTS 445
INTRODUCTION 445
MECHANISMS OF HEART FAILURE IN HYPERTROPHIC CARDIOMYOPATHY 445
Left Ventricular Outflow Tract Obstruction 445
Mitral Regurgitation 446
Diastolic Dysfunction 446
Systolic Dysfunction 446
Pulmonary hypertension 446
Atrial fibrillation 446
ALCOHOL SEPTAL ABLATION 447
History 447
EVIDENCE OF BENEFIT 448
Decrease of Left Ventricular Outflow Tract Obstruction 448
Regression of Septal Hypertrophy 449
Improvement of Mitral Regurgitation 449
Improvement of Diastolic Dysfunction 449
Functional Status and Mortality 450
Longevity 450
SUMMARY 451
REFERENCES 451
Renal Denervation to Modify Hypertension and the Heart Failure State 453
KEY POINTS 453
INTRODUCTION 453
RENAL DENERVATION AND RESISTANT HYPERTENSION 453
Pathogenesis 454
Renal Denervation in Experimental Animal Models of Resistant Hypertension 454
Surgical Renal Denervation 454
Catheter-Based Renal Denervation 455
RENAL DENERVATION AND HEART FAILURE 456
Pathogenesis 456
Renal Denervation in Experimental Animal Models of Heart Failure 458
Renal Denervation in Heart Failure with Reduced Ejection Fraction 458
Renal Denervation in Heart Failure with Preserved Ejection Fraction 461
SUMMARY 461
REFERENCES 461
Prioritizing and Combining Therapies for Heart Failure in the Era of Mechanical Support Devices 465
KEY POINTS 465
GOALS DETERMINE PRIORITIZATION AND INTERVENTIONAL STRATEGY 465
ASSESSMENT OF HEMODYNAMIC STATUS AND MYOCARDIAL ISCHEMIA 466
Assessment of Myocardial Ischemia 466
Assessment of Hemodynamic Status 466
CARDIOGENIC SHOCK: A SPECIAL CIRCUMSTANCE 466
Importance of Recognizing Preshock 466
OPTIONS FOR PERCUTANEOUS MECHANICAL SUPPORT 466
CLINICAL SCENARIOS ILLUSTRATING ISCHEMIC HEART FAILURE STRATEGIES 467
High-risk Percutaneous Coronary Intervention 467
Prioritization Based on Hemodynamics and Acute Myocardial Ischemia 467
Elective percutaneous coronary intervention—hemodynamically stable 467
Hemodynamically unstable but non–acute coronary syndrome: sequenced or deferred percutaneous coronary interventions 468
Case illustration: high-risk percutaneous coronary intervention in ischemic cardiomyopathy 468
Initial stabilization 468
Supported high-risk complex percutaneous coronary intervention 469
Hemodynamic instability during acute coronary syndrome 469
Intervention sequencing and escalation 470
Acute Coronary Syndrome Patients with Pulmonary Congestion but Intact Blood Pressure and Perfusion 470
Acute Coronary Syndrome Patients with Pulmonary Congestion and Intact Blood Pressure but Clinical Hypoperfusion: Preshock 470
Acute Coronary Syndrome Patients with Cardiogenic Shock 470
Case illustration: acute anterior ST segment elevation myocardial infarction, cardiac arrest, and cardiogenic shock 471
Case illustration: escalation of support in anterior ST segment elevation myocardial infarction with cardiogenic shock 472
Valvular Heart Disease and Complex Heart Failure Syndromes 473
Case illustration: impella-supported aortic valvuloplasty and high-risk percutaneous coronary intervention 473
Valvular heart disease 473
Case illustration: severe mitral regurgitation and aortic stenosis 474
Decompensated left ventricular pump failure 474
Escalating therapies 475
Escalation step 1 475
Escalation step 2 476
Escalation step 3 476
Right Heart Failure Syndromes 477
Acute right ventricular infarction 477
Prereperfusion therapies 477
Rhythm 477
Preload 477
Inotropes/vasopressors 477
Reperfusion therapy 477
Persistent hemodynamic compromise in acute right ventricular infarciton 478
Right ventricular shock due to acute pulmonary embolus 478
Acute right ventricular pump failure post–left ventricular assist device or cardiovascular surgery 478
Chronic right ventricular failure 479
REFERENCES 479
Integrating Interventional Cardiology and Heart Failure Management for Cardiogenic Shock 481
KEY POINTS 481
THE SPECTRUM OF ADVANCED HEART FAILURE AND CARDIOGENIC SHOCK 481
CHANGING OBJECTIVES FOR THE MANAGEMENT OF CARDIOGENIC SHOCK 482
MECHANICAL CIRCULATORY SUPPORT: INTERVENTIONAL TOOLS FOR COMPLEX HEART FAILURE AND SHOCK 482
THE HEART TEAM: AN EVOLVING MULTISPECIALTY COLLABORATION 483
BEYOND SHOCK: THE EXPANDING ROLE OF INTERVENTIONAL CARDIOLOGY 483
INTERVENTIONAL HEART FAILURE TRAINING: IS THIS RIGHT FOR ME? 484
REFERENCES 484