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Urology, An Issue of Physician Assistant Clinics, E-Book

Urology, An Issue of Physician Assistant Clinics, E-Book

Todd J. Doran

(2017)

Additional Information

Book Details

Abstract

This issue of Physician Assistant Clinics, Guest Edited by Todd J. Doran, Ed.D., PA-C, DFAAPA, is devoted to Urology. Articles in this issue include: Male Factor Infertility; Elevated PSA/PCa Screening; PSA Recurrence/Advanced PCa; Hematuria; Kidney Stones; Frequent Urinary Tract Infection; Female Urinary Incontinence; Lower Urinary Tract Symptoms (LUTS); Erectile Dysfunction; Hypogonadism; Neurogenic Bladder; and Vesicoureteral Reflux.

Table of Contents

Section Title Page Action Price
Front Cover Cover
Urology i
Copyright \r ii
CME Accreditation Page iii
PROGRAM OBJECTIVE iii
TARGET AUDIENCE iii
LEARNING OBJECTIVES iii
ACCREDITATION iii
DISCLOSURE OF CONFLICTS OF INTEREST iii
UNAPPROVED/OFF-LABEL USE DISCLOSURE iii
TO ENROLL iii
METHOD OF PARTICIPATION iv
CME INQUIRIES/SPECIAL NEEDS iv
Contributors v
CONSULTING EDITOR v
EDITOR v
AUTHORS v
Contents vii
Foreword: Recertification—Really? vii
Preface: Plumbing Department on Aisle 2 vii
Prostate Cancer Screening vii
Metastatic Castrate-Resistant Prostate Cancer Practical Review vii
Evaluation and Workup of Hematuria in Adults vii
Kidney Stones viii
Frequent Urinary Tract Infection viii
Female Urinary Incontinence viii
Male Lower Urinary Tract Symptoms viii
Neurogenic Bladder and Its Management ix
Erectile Dysfunction ix
Hypogonadism: Evaluation Management and Treatment Considerations ix
Male Infertility ix
PHYSICIAN ASSISTANT CLINICS\r\r xi
FORTHCOMING ISSUES xi
April 2018 xi
July 2018 xi
October 2018 xi
RECENT ISSUES xi
October 2017 xi
July 2017 xi
April 2017 xi
Foreword: Recertification—Really?\r xiii
Preface:\rPlumbing Department on Aisle 2 xv
SUPPLEMENTARY DATA xvi
Prostate Cancer Screening 1
Key points 1
OVERVIEW 1
CONTROVERSIES OF PROSTATE-SPECIFIC ANTIGEN TESTING 1
GUIDELINES 2
MANAGING AN ELEVATED PROSTATE-SPECIFIC ANTIGEN 2
BEYOND THE PROSTATE-SPECIFIC ANTIGEN TEST 3
DIGITAL RECTAL EXAMINATION 4
AGE-SPECIFIC REFERENCE RANGES 4
PROSTATE-SPECIFIC ANTIGEN VELOCITY 4
FREE PROSTATE-SPECIFIC ANTIGEN 4
PROSTATE HEALTH INDEX 5
4KSCORE 5
RISK CALCULATORS 5
IMAGING TECHNIQUES 5
SUMMARY 6
REFERENCES 6
Metastatic Castrate-Resistant Prostate Cancer Practical Review 11
Key points 11
DEFINITIONS 11
INTRODUCTION 12
EVALUATION OF PATIENTS WITH METASTATIC CASTRATE-RESISTANT PROSTATE CANCER 12
General Considerations 12
History 12
Physical examination 12
Laboratory evaluation 13
Imaging 13
Frequency of visits 13
Adjunctive services 14
TREATMENT CONSIDERATIONS 14
Androgen Deprivation Therapy 14
Oral therapy 14
Injection therapy 15
Therapies for Castrate-Resistant Prostate Cancer 15
Sipuleucel-T 15
Enzalutamide 16
Abiraterone 16
Radium-223 16
Docetaxel 17
Cabazitaxel 18
ADJUVANT TREATMENT AND EVALUATION CONSIDERATIONS 18
Hot Flashes 18
Gynecomastia 18
Bone Health 18
SUMMARY 19
REFERENCES 19
Evaluation and Workup of Hematuria in Adults 23
Key points 23
DEFINITION 23
EPIDEMIOLOGY 24
ETIOLOGY 24
PATIENT HISTORY 25
Medications 27
Past Medical History 27
Past Surgical History 27
Social History 27
Physical Examination 27
HEMATURIA WORKUP 28
LABORATORY TESTING 29
IMAGING 29
FOLLOW-UP 31
Guidelines for Workup for Microscopic Hematuria 32
SUMMARY 33
REFERENCES 34
Kidney Stones 37
Key points 37
EPIDEMIOLOGY 37
Demographics 38
Environment 38
Comorbidities 38
PATHOPHYSIOLOGY 38
Calcium Stones 38
Hypercalciuria 39
Hyperoxaluria 39
Frequent Urinary Tract Infection 55
Key points 55
RECURRENT URINARY TRACT INFECTION 60
WORKUP OF RECURRENT URINARY TRACT INFECTION 60
PREVENTION STRATEGIES AND TREATMENT 61
ANTIBIOTIC STEWARDSHIP 62
STERILE PYURIA 64
REFERENCES 65
Female Urinary Incontinence 69
Key points 69
TYPES OF URINARY INCONTINENCE 70
Stress Urinary Incontinence 70
Urgency Urinary Incontinence 70
Mixed Incontinence 70
Functional Urinary Incontinence 70
Continuous Urinary Incontinence 71
Overflow Urinary Incontinence 71
EVALUATION OF THE INCONTINENT PATIENT 71
PHYSICAL EXAMINATION OF THE INCONTINENT PATIENT 73
DIAGNOSTIC STUDIES IN THE INCONTINENT FEMALE 75
TREATMENT OF FEMALE INCONTINENCE 76
Stress Urinary Incontinence 77
Urgency Incontinence 78
CHALLENGING INCONTINENCE PATIENTS 80
SUMMARY 80
REFERENCES 81
Male Lower Urinary Tract Symptoms 83
Key points 83
INTRODUCTION 83
EVALUATION OF LOWER URINARY TRACT SYMPTOMS 84
History 84
Physical Examination 85
Laboratory Testing 86
Special Testing 86
TREATMENT 87
INDICATIONS FOR UROLOGIC REFERRAL 93
SURGICAL OPTIONS 93
Minimally Invasive 93
Surgical 93
SUMMARY 101
REFERENCES 101
Neurogenic Bladder and Its Management 103
Key points 103
BACKGROUND 103
RISK FACTORS AND EPIDEMIOLOGY 104
EXAMINATION 104
Laboratory Examination 104
Urodynamics 104
DISEASES THAT CONTRIBUTE TO NEUROPATHIC VOIDING DYSFUNCTION 105
Cortical Lesions 105
Parkinson Disease 105
Cerebral Palsy 105
Disease Primarily Involving the Spinal Cord 105
Spinal cord injuries 106
Multiple sclerosis 106
Transverse myelitis 107
Spina bifida 107
DISEASE DISTAL TO THE SPINAL CORD 107
TREATMENT OF VOIDING DYSFUNCTION AND GOALS OF MANAGEMENT 108
REFERENCES 109
Erectile Dysfunction 113
Key points 113
HISTORY 113
EPIDEMIOLOGY AND RISK FACTORS 114
ERECTILE PHYSIOLOGY 114
ETIOLOGIES AND ASSOCIATED CONDITIONS 115
EVALUATION: HISTORY 117
EVALUATION: PHYSICAL EXAMINATION 119
EVALUATION: LABORATORY VALUES AND OTHER TESTS 119
MANAGEMENT 120
Phosphodiesterase Type 5 Inhibitors 120
Vacuum Erection Device 122
Intraurethral Suppositories 122
Intracavernosal Injections 122
Penile Implant Surgery 123
SUMMARY 124
REFERENCES 124
Hypogonadism 129
Key points 129
INTRODUCTION 129
EVALUATION OF HYPOGONADISM 130
TESTOSTERONE REPLACEMENT THERAPY 132
HYPOGONADISM AND PROSTATE CANCER 132
HYPOGONADISM AND CARDIOMETABOLIC SYNDROME 132
DISCUSSION 135
SOCIETAL ISSUES 135
SUMMARY 136
REFERENCES 136
Male Infertility 139
Key points 139
INTRODUCTION 139
EVALUATION OF THE MALE 140
HISTORY 140
PHYSICAL EXAMINATION 141
Routine Serum Laboratory Testing 142
SEMEN ANALYSIS 142
PROPER REFERRAL 143
FURTHER TESTING 143
Klinefelter Syndrome: 47, XXY 144
EXOGENOUS TESTOSTERONE 145
REFERENCES 146