Menu Expand
Thoracic Imaging The Requisites E-Book

Thoracic Imaging The Requisites E-Book

Jo-Anne O Shepard

(2018)

Additional Information

Book Details

Abstract

Now in its 3rd Edition, this outstanding volume by Dr. Jo-Anne O. Shepard in the popular Requisites series thoroughly covers the fast-changing field of chest imaging. Ideal for residency, clinical practice, and board certification, it covers the full range of basic and advanced modalities used in thoracic imaging including digital radiography, chest fluoroscopy, CT, PET, and MRI. Compact and authoritative, Thoracic Imaging: The Requisites provides the up-to-date conceptual, factual, and interpretive information you need for success on exams and in clinical practice.


Table of Contents

Section Title Page Action Price
Front Cover cover
Inside Front Cover ifc1
Half title page i
The Requisites Series ii
Thoracic Imaging The Requisites iii
Copyright Page iv
Dedication v
Foreword vi
Preface vii
Contributors viii
Table Of Contents xi
Acknowledgments xii
1 Radiologic Techniques and Dose Reduction Strategies in Chest Imaging 1
Introduction 1
Conventional, Computed, and Digital Radiography 1
Chest Radiography: Projections and Views 1
Digital Subtraction Techniques in Chest Radiography 3
Chest Fluoroscopy 4
Digital Tomosynthesis in the Chest 5
Computed Tomography 5
Applications of Computed Tomography of the Chest 6
Dual-Energy Computed Tomography of the Chest 7
Dual-Energy Computed Tomography Techniques 7
Dual-Energy Computed Tomography Image Processing 8
Radiation Doses With Dual-Energy Computed Tomography 9
Clinical Applications of Dual-Energy Computed Tomography 10
Computed Tomography Protocols and Radiation Dose 11
Scan Parameters 12
Tube Current 12
Tube Potential 12
Gantry Rotation Time 12
Detector Configuration or Beam Collimation 13
Pitch 13
Scan Length 13
Number of Phases 13
Indication-Specific Chest Computed Tomography Protocols 13
Routine Chest Protocol 14
Pulmonary Embolism Protocol 14
Lung Nodule Follow-up Computed Tomography 14
Low-Dose Computed Tomography for Lung Cancer Screening 14
Tracheal or Airway Protocol Computed Tomography 15
High-Resolution Computed Tomography for Diffuse Lung Diseases 16
Contrast Usage in Chest Computed Tomography: Guidelines 17
Conclusions 18
Suggested Readings 18
2 Normal Anatomy and Atelectasis 19
Normal Anatomy 19
Trachea and Main Bronchi 19
Lobar Bronchi and Bronchopulmonary Segments 19
Right Side 19
Left Side 22
Variants 22
Pulmonary Vessels 23
Pericardial Recesses 23
Fissures 25
The Diaphragm 25
Normal Mediastinal Contours: The Frontal Projection 27
Normal Mediastinal Contours: The Lateral Projection 36
The Hila: The Frontal Projection 41
The Hila: The Lateral Projection 42
Atelectasis 47
Mechanisms of Atelectasis 47
Patterns of Atelectasis 47
Rounded Atelectasis 47
Total Collapse of the Lung 47
Lobar Collapse 49
Right Upper Lobe Atelectasis 49
Left Upper Lobe Atelectasis 49
Right Middle Lobe Atelectasis 51
Lower Lobe Atelectasis 51
Combined Right Upper and Right Middle Lobe Atelectasis 52
Combined Right Middle and Right Lower Lobe Atelectasis 52
Subsegmental Atelectasis 52
Suggested Readings 60
3 Thoracic Magnetic Resonance Imaging 61
Introduction 61
Uses of Thoracic Magnetic Resonance Imaging 61
Problem Solving 61
Full Chest Imaging and Screening 61
Strengths of Magnetic Resonance Imaging Over Computed Tomography 62
No Ionizing Radiation 62
Better Soft Tissue Contrast 62
Impact on Clinical Decision Making 63
Value 63
Tissue Characterization and Magnetic Resonance Imaging Interpretation 63
Cyst Versus Solid 64
Blood Products 68
Calcification 68
Macroscopic Fat 68
Microscopic Fat 68
Chemical Shift Ratio Region-of-Interest Placement and Calculation 69
Signal Intensity Index Region-of-Interest Placement and Calculation 72
Lymph Nodes, Acute Inflammatory Lesions, and Most Thoracic Neoplasms 73
Fibrous Tissue 73
Cartilage 74
Smooth Muscle 74
Lesion Vascularity 76
Restricted Diffusion 76
Concept of Matching Lesions 76
Lesion Measurement 76
Detection of Pulmonary Nodules 76
THORACIC Magnetic Resonance Protocoling and Performance 82
Goals 82
Successful Breath-Hold Imaging 82
Free-Breathing Techniques 84
The Magnetic Resonance Sniff Test 84
Cardiac Gating 84
Slice Thickness Selection 84
Basic Thoracic Magnetic Resonance Protocol 84
Rationale for Each Pulse Sequence in the Protocol 84
T1-Weighted Imaging 84
T2-Weighted Imaging 85
Dynamic Contrast-Enhanced Imaging 85
Optional Pulse Sequences 85
Suggested Readings 86
4 PET-CT and PET-MRI 88
Introduction 88
Technique 88
PET-CT 88
PET-MR 89
Advantages 89
Pitfalls 92
Suggested Readings 96
5 The Mediastinum 97
Introduction 97
Mediastinal Landmarks 97
Mediastinal Compartments and Their Associated Lesions 97
The Prevascular Compartment or Anterior Mediastinum 97
The Visceral Compartment or Middle Mediastinum 97
The Paravertebral Compartment or Posterior Mediastinum 98
Multicompartment Lesions 98
Imaging Workup 99
Chest Radiography 99
Fluoroscopy 99
Computed Tomography 99
Magnetic Resonance Imaging 100
Positron Emission Tomography 101
Mediastinal Masses 103
Prevascular and Anterior Mediastinal Masses 103
Thymic Lesions 103
Normal Thymus. 103
Thymic Hyperplasia. 104
Thymic Cysts. 106
Thymolipoma. 107
Thymic Epithelial Tumors. 107
Thymic Neuroendocrine Tumors. 110
Thyroid Lesions 110
Mediastinal Lymphoma 111
Mediastinal Germ Cell Tumors 114
Pericardiophrenic Masses 114
Pericardial Fat Pads. 114
Pericardial Cysts. 115
Pericardiophrenic Lymphadenopathy. 115
Visceral and Middle Mediastinal Masses and Common Vascular Lesions 115
Lymphadenopathy 115
Congenital-Developmental Cysts 117
Tracheal Lesions 117
Esophageal Lesions 117
Achalasia. 117
Esophagitis. 117
Esophageal Injury. 118
Esophageal Diverticula. 120
Esophageal Varices. 121
Hiatal Hernia. 121
Esophageal Neoplasms. 122
Selected Vascular Lesions 124
Aortic Aneurysm. 124
Traumatic Aortic Pseudoaneurysm. 125
Aortic Dissection. 125
Aberrant Subclavian Artery. 126
Azygous Continuation of the Inferior Vena Cava. 126
Paravertebral and Posterior Mediastinal Masses 126
Neurogenic Tumors 126
Peripheral Nerve Sheath Tumors. 126
Sympathetic Ganglion Tumors. 128
Paragangliomas. 128
Other Paravertebral and Vertebral Lesions 128
Neuroenteric Cysts. 128
Meningoceles. 128
Extramedullary Hematopoiesis. 129
Traumatic Lesions. 129
Diffuse Mediastinal Processes 131
Mediastinal Lipomatosis 131
Acute Mediastinitis 131
Fibrosing Mediastinitis 132
Pneumomediastinum 136
Suggested Readings 136
6 The Airways 137
Keywords 137.e1
Normal Anatomy 137
Trachea 137
Bronchi 137
Imaging of the Airways 137
General 137
Radiography 137
Multidetector Computed Tomography 138
Magnetic Resonance Imaging 138
FDG PET/CT 138
Abnormalities of the Trachea 138
Tracheal Diverticula 138
Tracheal Stenosis 138
Idiopathic Laryngotracheal Stenosis 139
Postintubation Injury 139
Posttraumatic Tracheal and Bronchial Stenosis 140
Saber-Sheath Trachea 140
Tracheopathia Osteochondroplastica 140
Relapsing Polychondritis 140
Granulomatosis With Polyangiitis 141
Amyloidosis 142
Sarcoidosis 143
Infection 143
Rhinosclerosis. 143
Tuberculosis. 143
Tracheobronchomegaly (Mounier-Kuhn Syndrome) 144
Tracheal Neoplasms 144
Malignant Neoplasms 144
Squamous Cell Carcinoma. 144
Adenoid Cystic Carcinoma. 144
Benign Neoplasms 145
Squamous Cell Papilloma and Tracheobronchial Papillomatosis. 145
Tracheobronchomalacia 146
Abnormalities of the Bronchi 147
Bronchial Neoplasms 147
Carcinoid Tumors 147
Mucoepidermoid Carcinoma 147
Hamartoma 147
Lipoma 147
Other Endobronchial Lesions 148
Broncholithiasis 148
Foreign Bodies 149
Airway Fistulas 151
Esophagorespiratory Fistulas 151
Other Fistulas 151
Bronchiectasis 152
Mucoid Impaction 154
Cystic Fibrosis 154
Allergic Bronchopulmonary Aspergillosis 155
Primary Ciliary Dyskinesia 155
Other Etiologies 155
Bronchiolitis 155
Overview of Imaging Findings 156
Infectious Bronchiolitis 156
Respiratory Bronchiolitis and Respiratory Bronchiolitis–Associated Interstitial Lung Disease 156
Follicular Bronchiolitis 157
Diffuse Panbronchiolitis 157
Constrictive Bronchiolitis 157
Conclusions 157
Suggested Reading 157
7 The Pleura, Diaphragm, and Chest Wall 159
Pleura 159
Anatomy and Physiology 159
Pleural Effusions 159
Specific Types of Pleural Effusions and Their Imaging Features 159
Freely Layering Pleural Effusion 159
Subpulmonic Pleural Effusion 160
Loculated Pleural Effusion 161
Hydropneumothorax 162
Empyema 162
Hemothorax 165
Chylothorax 165
Pneumothorax 165
Tension Pneumothorax 167
Pneumothorax Ex Vacuo 167
Pneumonectomy Space 167
Asbestos-Related Pleural Disease (see Chapter 19) 167
Non–Asbestos-Related Pleural Thickening 168
Fibrothorax 168
Thoracolithiasis 168
Benign Pleural Tumors 168
Solitary Fibrous Tumor of the Pleura (Benign and Malignant) 168
Pleural Lipoma 172
Malignant Pleural Disease 172
Pleural Metastases 172
Mesothelioma 173
Pleural Lymphoma 175
Diaphragm 176
Anatomy and Function 176
Diaphragmatic Eventration 176
Diaphragmatic Weakness and Paralysis 176
Diaphragmatic Hernias 179
Hiatal Hernia 179
Bochdalek Hernia 179
Morgagni Hernia 179
Traumatic Diaphragmatic Injury 179
Chest Wall 179
Congenital and Developmental Anomalies 179
Pectus Excavatum 179
Pectus Carinatum 180
Poland Syndrome 180
Neurofibromatosis Type 1–Related Changes 180
Metabolic Conditions 180
Renal Osteodystrophy 180
Sickle Cell Disease 181
Paget Disease 181
Inflammatory Conditions 181
Ankylosing Spondylitis 181
SAPHO Syndrome 182
Infectious Diseases 182
Chest Wall Infections 182
Diskitis-Osteomyelitis 183
Benign Tumors and Tumor-like Conditions 183
Lipoma 183
Neurogenic Tumors 187
Hemangioma 187
Enchondroma 188
Osteochondroma 188
Elastofibroma Dorsi 189
Fibrous Dysplasia 189
Malignant Tumors 189
Chest Wall Metastasis 189
Multiple Myeloma 189
Chondrosarcoma 189
Iatrogenic and Postsurgical Conditions 189
Suggested Readings 192
8 Congenital Thoracic Malformations 193
Introduction 193
Trachea 193
Tracheomalacia 193
Congenital Tracheal Stenosis 193
Congenital Tracheobronchomegaly 194
Tracheoesophageal Fistula 194
Tracheal Bronchus 194
Bronchi 196
Accessory Cardiac Bronchus 196
Bronchial Isomerism 196
Bronchial Atresia 196
Congenital Bronchiectasis 197
Lungs 197
Pulmonary Underdevelopment 197
Congenital Lobar Overinflation 197
Congenital Pulmonary Airway Malformation 199
Pulmonary Sequestration 199
Intralobar Sequestration 200
Extralobar Sequestration 200
Mediastinum 200
Foregut Duplication Cysts 200
Bronchogenic Cysts 200
Esophageal Duplication Cysts 201
Neurenteric Cysts 201
Thymic Cysts 202
Pulmonary Vessels 202
Anomalies of the Pulmonary Arteries 202
Proximal Interruption 202
Anomalous Origin of the Left Pulmonary Artery From the Right 204
Pulmonary Artery Stenosis or Coarctation 204
Congenital Aneurysms of the Pulmonary Arteries 204
Anomalies of the Pulmonary Veins 204
Pulmonary Vein Stenosis and Unilateral Pulmonary Vein Atresia 204
Pulmonary Varix 205
Meandering Pulmonary Vein 205
Anomalous Pulmonary Venous Drainage 205
Anomalies Involving Arteries and Veins 206
Congenital Hypogenetic Lung Syndrome 206
Systemic Arterial Supply to Normal Lung 206
Pulmonary Arteriovenous Malformation 207
Congenital Anomalies of the Lymphatics 208
Lymphangiectasis 208
Lymphangioma 208
Lymphangiomatosis 208
Suggested Readings 209
9 Thoracic Lines and Tubes 210
Introduction 210
Airway Tubes 210
Endotracheal Tube 210
Tracheostomy Tube 212
Vascular Lines 212
Central Venous Catheters 212
Pulmonary Artery Catheter 215
Pleural and Enteric Tubes 216
Chest Tubes 216
Nasogastric and Orogastric Tube and Feeding Tube 217
Respiratory and Hemodynamic Support Devices 219
Intraaortic Balloon Pump 219
Extracorporeal Membrane Oxygenation 221
Venovenous ECMO 221
Venoarterial Extracorporeal Membrane Oxygenation 221
Extracorporeal Membrane Oxygenation Complications 222
Ventricular Assist Devices 222
Cardiac Conduction Devices 223
Cardiac Pacemakers 223
Implantable Cardioverter Defibrillator 225
Suggested Readings 225
10 Acute Thoracic Conditions in the Intensive Care Unit 226
Introduction 226
Pulmonary Disease 226
Atelectasis 226
Aspiration 226
Pneumonia 226
Pulmonary Embolism 227
Pulmonary Edema 229
Acute Exacerbation of Interstitial Lung Disease 233
Pulmonary Hemorrhage 233
Abnormal Air Collections 234
Subcutaneous Air 234
Pneumothorax 234
Pulmonary Interstitial Emphysema 234
Pneumomediastinum 235
Pneumopericardium 236
Pneumoperitoneum 236
Fluid Collections 237
Pleural Effusions 237
Pericardial Effusion 237
Infusothorax 237
Hemothorax, Empyema, and Chylothorax 237
Suggested Readings 237
11 Pulmonary Embolus and Pulmonary Vascular Diseases 238
Abstract 238.e1
Keywords 238.e1
Pulmonary Embolus 238
Imaging of Pulmonary Embolus 238
Chest Radiography 238
Ventilation/Perfusion Scintigraphy 239
Evaluation of the Leg Veins 239
Computed Tomography 240
Angiography 245
Magnetic Resonance Angiography 247
Nonthrombotic Pulmonary Embolus 248
Septic Embolus 248
Fat Embolus 248
Air Embolus 248
Amniotic Fluid Embolus 248
Tumor Embolus 248
Foreign Body Embolus 248
Pulmonary Hypertension 248
Imaging of Pulmonary Hypertension 249
Chest Radiography 249
Ventilation/Perfusion Scintigraphy 249
Computed Tomography 249
Magnetic Resonance Imaging 251
Pulmonary Vasculitis 252
Large-Vessel Vasculitis 252
Medium-Vessel Vasculitis 253
Small-Vessel Vasculitis 253
Antineutrophil Cytoplasm Antibody–Associated Vasculitis 253
Granulomatosis With Polyangiitis. 253
Eosinophilic Granulomatosis With Polyangiitis. 254
Microscopic Polyangiitis. 255
Immune Complex Small-Vessel Vasculitides 255
Antiglomerular Basement Membrane Disease. 255
Immunoglobulin A Vasculitis. 255
Hypocomplementemic Urticarial Vasculitis. 255
Cryoglobulinemic Vasculitis. 255
Variable Vessel Vasculitis 255
Other Causes of Vasculitis 256
Pulmonary Artery Pseudoaneurysm 256
Pulmonary Arteriovenous Malformation 257
Primary Pulmonary Artery Sarcoma 257
Suggested Readings 258
12 The Postoperative Chest 259
Introduction 259
Lung Surgeries 259
Open and Minimally Invasive 259
Wedge Resection 259
Bullectomy and Blebectomy 259
Volume Reduction Surgery 259
Segmentectomy 259
Lobectomy 260
Pneumonectomy 261
Extrapleural Pneumonectomy 262
Complications 263
Air Leak 263
Bronchopleural Fistula 263
Lobar Torsion 263
Venous Infarct 264
Cardiac Herniation or Torsion 265
Diaphragmatic Dehiscence 266
Other Early Complications 266
Tumor Recurrence 266
Postpneumonectomy Syndrome 267
Lung Transplantation 267
Technique 267
Complications 268
Reperfusion Edema 268
Anastomotic Dehiscence 268
Anastomotic Stricture 269
Rejection 269
Posttransplantation Lymphoproliferative Disorder 270
Other Complications 270
Pleural Procedures 270
Pleurodesis 270
Decortication and Pleurectomy 271
Open Pleural Drainage 271
Mediastinal Surgeries 271
Esophagectomy 271
Mediastinal Tumor Resection 272
Complications 273
Anastomotic Leak 273
Esophagopleural Fistula 273
Anastomotic Stricture 274
Chylothorax 274
Nerve Injury 274
Mediastinal Hematoma 274
Sternal Dehiscence and Osteomyelitis 275
Chest Wall Surgeries 275
Types and Techniques 275
Retained Surgical Foreign Bodies 275
Suggested Readings 278
13 Thoracic Trauma 279
Introduction 279
Pulmonary, Pleural, and Diaphragmatic Injuries 279
Lung Contusions and Lacerations 279
Tracheobronchial Injuries 280
Injuries of the Pleural Space 280
Pneumothorax 280
Hemothorax 281
Diaphragmatic Injuries 282
Mediastinal Injuries 283
Traumatic Aortic and Great Vessel Injuries 283
Esophageal Injuries 285
Cardiac and Pericardial Injuries 285
Thoracic Skeletal Injuries 285
Rib Fractures 285
Sternal and Clavicular Injuries 286
Thoracic Spine Injuries 286
Suggested Readings 288
14 Community-Acquired Pneumonia 289
Introduction 289
Mechanisms and Patterns of Infection 289
Inhalational Pneumonia 289
Lobar Pneumonia 289
Bronchopneumonia 290
Interstitial Pneumonia 291
Aspiration Pneumonia 293
Hematogenous and Direct Spread of Infection 293
Patterns of Host Response to Infection 294
Complications 296
Cavitation and Abscess 296
Pneumatocele Formation 296
Lymphadenopathy 297
Pleural Complications 297
Other Complications 298
Clinical Approach to Pneumonia 298
Bacterial Pneumonia 298
Viral Pneumonia 299
Fungal Pneumonia 300
Parasitic Infection 305
Conclusion 305
Suggested Readings 309
15 Pulmonary Disease in the Immunocompromised Patient 310
Introduction 310
Pulmonary Diseases 310
Pulmonary Infections 310
Bacterial Infection 310
Fungal Infection 313
Viral Infection 314
Malignant Neoplasms 314
Kaposi Sarcoma 314
Lymphoma 314
Lung Cancer 316
Lymphoproliferative Disorders 316
Other Pulmonary Disorders 317
Other Forms of Immunocompromise 317
Radiologic Patterns of Pulmonary Infections 317
Lobar or Segmental Consolidation 317
Nodules and Masses With Rapid Growth or Cavitation 318
Diffuse Lung Disease 319
Diagnostic and Therapeutic Approach 321
Suggested Readings 322
16 Mycobacterial Infection 323
Introduction 323
Tuberculous Mycobacterial Infection 323
Primary Tuberculosis 323
Consolidation 324
Lymphadenopathy 324
Pleural Infection 324
Pericardial Effusion 324
Healed Tuberculosis 324
Extrapulmonic Thoracic Tuberculosis 324
Postprimary Tuberculosis 328
Miliary Tuberculosis 329
Nontuberculous Mycobacterial Infection 333
Cavitary Form (Classic) 333
Bronchiectatic Form (Nonclassic) 333
Conclusion 333
Suggested Readings 334
17 Approach to Diffuse Lung Disease 335
Introduction 335
High-Resolution Computed Tomography Protocol 335
High-Resolution Computed Tomography Evaluation 335
Anatomy of the Secondary Pulmonary Lobule 336
Lung Interstitium 339
High-Resolution Computed Tomography Patterns 339
Nodular Pattern (Table 17.2) 340
Perilymphatic Nodules 340
Random Nodules 340
Centrilobular Nodules 340
Reticular Opacities (Table 17.3) 341
Interlobular Septal Thickening 344
Intralobular Lines 344
Honeycombing 346
Increased Attenuation (Table 17.4) 346
Ground-Glass Opacity 346
Consolidation 348
Decreased Attenuation (Table 17.5) 348
Emphysema 348
Cystic Disease 351
Mosaic Attenuation 354
Conclusion 354
Suggested Readings 354
18 Diffuse Lung Diseases 355
Introduction 355
Idiopathic Interstitial Pneumonias 355
Chronic Fibrosing Interstitial Pneumonias 355
Idiopathic Pulmonary Fibrosis 355
Nonspecific Interstitial Pneumonia 357
Acute and Subacute Fibrosing Interstitial Pneumonia 357
Organizing Pneumonia 357
Acute Interstitial Pneumonia 358
Smoking-Related Interstitial Pneumonias 359
Respiratory Bronchiolitis–Interstitial Lung Disease 359
Desquamative Interstitial Pneumonia 359
Rare Entities 360
Lymphocytic Interstitial Pneumonitis 360
Idiopathic Pleuroparenchymal Fibroelastosis 360
Connective Tissue Diseases 361
Rheumatoid Arthritis 361
Systemic Lupus Erythematosus 361
Mixed Connective Tissue Disease 361
Scleroderma 361
Myositis 362
Sjögren Syndrome 363
Hypersensitivity Pneumonitis 363
Hypersensitivity Pneumonitis–Specific Diseases 364
Farmer’s Lung 364
Humidifier Lung 364
Pigeon Breeder’s Lung 364
Hot Tub Lung 364
Sarcoidosis 365
Cystic Lung Diseases 366
Lymphangioleiomyomatosis 366
Pulmonary Langerhans Cell Histiocytosis 368
Other Diffuse Cystic Lung Diseases 369
Eosinophilic Lung Disease 370
Characteristics 370
Loeffler Syndrome 370
Chronic Eosinophilic Pneumonia 371
Acute Eosinophilic Pneumonia 371
Idiopathic Hypereosinophilic Syndrome 372
Parasitic Infections 372
Drug-Induced Lung Disease 372
Patterns of Injury 373
Noncardiogenic Pulmonary Edema 373
Pulmonary Hemorrhage 373
Pulmonary Fibrosis 373
Eosinophilic Pneumonia 373
Exogenous Lipoid Pneumonia 373
Drug-Induced Lupus Syndrome 373
Obliterative Bronchiolitis 373
Illicit Drug Use 373
Specific Drugs 374
Amiodarone 374
Nitrofurantoin 374
Methotrexate 374
Bleomycin 375
Interferon 375
Checkpoint Inhibitor Immunotherapy 375
Suggested Readings 376
19 Pneumoconioses 377
Introduction 377
Pathophysiology 377
International Labour Organization Classification of Pneumoconiosis 378
Mineral Dust Pneumoconiosis 379
Silicosis 379
Acute Silicosis 379
20 Obstructive Lung Diseases 391
Introduction 391
Chronic Obstructive Pulmonary Disease 392
Emphysema 392
Clinical Features 392
Pathologic Features 393
Imaging Features 395
Radiography 395
Computed Tomography 396
Clinical Indications, Applications, and Implications. 398
Differential Diagnosis. 399
Chronic Bronchitis 399
Clinical Features 399
21 Pulmonary Tumors and Lymphoproliferative Disorders 405
Lung Cancer 405
Risk Factors 405
Clinical Presentation 406
Classifications 406
Adenocarcinoma 406
Clinical Features. 406
Pathologic Features. 407
Imaging Features. 407
Squamous Cell Carcinoma 408
Clinical Features. 408
Pathologic Features. 408
Imaging Features. 408
Superior Sulcus Tumor 410
Clinical Features. 410
Imaging Features. 411
Neuroendocrine Tumors 411
Small Cell Lung Carcinoma 411
Clinical Features. 411
22 Incidental Pulmonary Nodule 428
Introduction 428
Approach to Assessment of Lung Nodules 428
Attenuation 428
Shape and Contour 430
Enhancement 430
Location 432
Size and Evolution 432
Management of Solid Nodules 433
Radiograph 433
Computed Tomography 435
Guidelines 435
Nodule Mimics 436
Management of Subsolid Nodules 437
Radiography 437
Computed Tomography 437
Transient Versus Persistent 437
Guidelines 437
Nodule Mimics 440
Suggested Readings 440
23 Lung Cancer Screening 441
Why Screen? 441
Who to Screen? 441
How to Screen? 442
Lung Nodule Assessment 442
Morphology 442
Size 446
Growth 446
Presence of Calcification or Fat 446
Pitfalls in Lung Cancer Screening 446
Lung Nodule Management Algorithms 446
Incidental Findings 447
Structured Reporting 448
Potential Harms of Low-Dose Computed Tomography Screening for Lung Cancer 448
False-Positive Results in the NLST Trial 448
Overdiagnosis 448
Radiation 448
The Future of Lung Cancer Screening 449
Conclusion 449
Suggested Reading 449
24 Lung Cancer Staging 450
Introduction 450
Imaging and Surgical Staging Procedures (Table 24.2) 451
Imaging Modalities 451
Surgical (Interventional) Procedures 451
Tumor, Node, Metastasis Classification 453
Primary Tumor 453
Nodal Involvement 456
Metastasis 457
Changes From the Last TNM Staging Edition 458
Group Stages and Treatment 458
Multiple Cancers 458
Suggested Readings 459
25 Interventional Techniques 460
Introduction 460
Biopsy of Lung and Mediastinum 460
Indications and Contraindications 460
Sedation Plan 460
Tools and Technical Principles 460
Procedure 461
Postprocedure Care 463
Complications 464
Percutaneous Localization Techniques 465
Thermal Ablation 466
Indications and Contraindications 466
Tools and Technical Principles 466
Sedation Plan 466
Procedure 466
Postprocedure Care 468
Complications 468
Thoracentesis and Pleural Drainage 469
Indications and Contraindications 469
Tools and Technical Principles 470
Sedation Plan 470
Procedure 470
Postprocedure Care 471
Complications 472
Suggested Readings 472
Index 473
A 473
B 473
C 474
D 475
E 475
F 476
G 476
H 476
I 477
J 477
K 477
L 477
M 478
N 479
O 480
P 480
Q 482
R 482
S 482
T 483
U 484
V 484
W 484
X 484
Y 484
Z 484
Inside Back Cover ibc1