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Book Details
Abstract
Gain a foundational understanding of gastrointestinal physiology and how the GI system functions in health and disease. Gastrointestinal Physiology, a volume in the Mosby Physiology Series, explains the fundamentals of this complex subject in a clear and concise manner, while helping you bridge the gap between normal function and disease with pathophysiology content throughout the book.
- Helps you easily master the material in a systems-based curriculum with learning objectives, Clinical Concept boxes, highlighted key words and concepts, chapter summaries, self-study questions, and a comprehensive exam.
- Keeps you current with recent advances in gastrointestinal physiology with coverage of the physiological significance of gastrointestinal peptides; the regulation of mucosal growth and cancer; details surrounding acid secretion and peptic ulcers; and more.
- Includes clear, 2-color diagrams that simplify complex concepts.
- Features clinical commentaries that show you how to apply what you've learned to real-life clinical situations.
- Covers the regulation of pancreatic secretion and gallbladder contraction; the transport processes for the absorption of nutrients; facts about fat absorption; and the regulation of food intake.
Complete the Mosby Physiology Series! Systems-based and portable, these titles are ideal for integrated programs.
- Blaustein, Kao, & Matteson: Cellular Physiology and Neurophysiology
- Cloutier: Respiratory Physiology
- Koeppen & Stanton: Renal Physiology
- Pappano & Weir: Cardiovascular Physiology
- White, Harrison, & Mehlmann: Endocrine and Reproductive Physiology
- Hudnall: Hematology: A Pathophysiologic Approach
Table of Contents
| Section Title | Page | Action | Price |
|---|---|---|---|
| Front Cover | Cover | ||
| IFC | ES1 | ||
| GASTROINTESTINAL PHYSIOLOGY | i | ||
| Series page | ii | ||
| GASTROINTESTINAL PHYSIOLOGY | iii | ||
| Copyright | iv | ||
| PREFACE | v | ||
| CONTENTS | vi | ||
| 1 - Regulation: Peptides of the Gastrointestinal Tract | 1 | ||
| GENERAL CHARACTERISTICS | 1 | ||
| DISCOVERY | 2 | ||
| CHEMISTRY | 2 | ||
| DISTRIBUTION AND RELEASE | 4 | ||
| ACTIONS AND INTERACTIONS | 6 | ||
| CANDIDATE HORMONES | 8 | ||
| NEUROCRINES | 8 | ||
| PARACRINES | 9 | ||
| 2 - Regulation: Nerves and Smooth Muscle | 12 | ||
| ANATOMY OF THE AUTONOMIC NERVOUS SYSTEM | 12 | ||
| NEUROHUMORAL REGULATION OF GASTROINTESTINAL FUNCTION | 14 | ||
| ANATOMY OF THE SMOOTH MUSCLE CELL | 15 | ||
| SMOOTH MUSCLE CONTRACTION | 15 | ||
| 3 - Swallowing | 20 | ||
| CHEWING | 20 | ||
| PHARYNGEAL PHASE | 20 | ||
| ESOPHAGEAL PERISTALSIS | 21 | ||
| RECEPTIVE RELAXATION OF THE STOMACH | 25 | ||
| 4 - Gastric Emptying | 28 | ||
| ANATOMIC CONSIDERATIONS | 28 | ||
| CONTRACTIONS OF THE ORAD REGION OF THE STOMACH | 29 | ||
| CONTRACTIONS OF THE CAUDAD REGION OF THE STOMACH | 29 | ||
| CONTRACTIONS OF THE GASTRODUODENAL JUNCTION | 31 | ||
| CONTRACTIONS OF THE PROXIMAL DUODENUM | 31 | ||
| REGULATION OF GASTRIC EMPTYING | 31 | ||
| 5 - Motility of the Small Intestine | 37 | ||
| ANATOMIC CONSIDERATIONS | 37 | ||
| TYPES OF CONTRACTIONS | 37 | ||
| PATTERNS OF CONTRACTIONS | 38 | ||
| VOMITING | 42 | ||
| 6 - Motility of the Large Intestine | 45 | ||
| ANATOMIC CONSIDERATIONS | 45 | ||
| CONTRACTIONS OF THE CECUM AND ASCENDING COLON | 46 | ||
| CONTRACTIONS OF THE DESCENDING AND SIGMOID COLON | 47 | ||
| MOTILITY OF THE RECTUM AND ANAL CANAL | 47 | ||
| CONTROL OF MOTILITY | 48 | ||
| 7 - Salivary Secretion | 52 | ||
| FUNCTIONS OF SALIVA | 52 | ||
| ANATOMY AND INNERVATION OF THE SALIVARY GLANDS | 53 | ||
| COMPOSITION OF SALIVA | 54 | ||
| Inorganic Composition | 54 | ||
| Organic Composition | 58 | ||
| REGULATION OF SALIVARY SECRETION | 58 | ||
| 8 - Gastric Secretion | 62 | ||
| FUNCTIONAL ANATOMY | 62 | ||
| SECRETION OF ACID | 65 | ||
| ORIGIN OF THE ELECTRICAL POTENTIAL DIFFERENCE | 66 | ||
| ELECTROLYTES OF GASTRIC JUICE | 66 | ||
| STIMULANTS OF ACID SECRETION | 67 | ||
| Role of Histamine in Acid Secretion | 67 | ||
| STIMULATION OF ACID SECRETION | 68 | ||
| Cephalic Phase | 68 | ||
| Gastric Phase | 68 | ||
| Release of Gastrin | 69 | ||
| Intestinal Phase | 70 | ||
| INHIBITION OF ACID SECRETION | 70 | ||
| PEPSIN | 71 | ||
| MUCUS | 73 | ||
| INTRINSIC FACTOR | 73 | ||
| GROWTH OF THE MUCOSA | 74 | ||
| 9 - Pancreatic Secretion | 79 | ||
| FUNCTIONAL ANATOMY | 79 | ||
| MECHANISMS OF FLUID AND ELECTROLYTE SECRETION | 80 | ||
| MECHANISMS OF ENZYME SECRETION | 82 | ||
| REGULATION OF SECRETION | 83 | ||
| Cephalic Phase | 83 | ||
| Gastric Phase | 83 | ||
| Intestinal Phase | 83 | ||
| CELLULAR BASIS FOR POTENTIATION | 85 | ||
| RESPONSE TO A MEAL | 86 | ||
| 10 - Bile Secretion and Gallbladder Function | 90 | ||
| OVERVIEW OF THE BILIARY SYSTEM | 90 | ||
| CONSTITUENTS OF BILE | 90 | ||
| Bile Acids and the Enterohepatic Circulation | 94 | ||
| Cholesterol and Phospholipids | 95 | ||
| Bilirubin | 95 | ||
| Water and Electrolytes | 96 | ||
| GALLBLADDER FUNCTION | 97 | ||
| Filling | 97 | ||
| Concentration of the Bile | 97 | ||
| EXPULSION OF BILE | 98 | ||
| 11 - Digestion and Absorption of Nutrients | 102 | ||
| STRUCTURAL-FUNCTIONAL ASSOCIATIONS | 102 | ||
| DIGESTION | 102 | ||
| ABSORPTION | 103 | ||
| Mucosal Membrane | 103 | ||
| Transport Processes | 103 | ||
| ADAPTATION OF DIGESTIVE AND ABSORPTIVE PROCESSES | 104 | ||
| CARBOHYDRATE ASSIMILATION | 104 | ||
| Principal Dietary Forms | 104 | ||
| Digestion | 104 | ||
| Absorption of Digestion Products | 106 | ||
| Regulation of Absorption | 106 | ||
| Abnormalities in Carbohydrate Assimilation | 106 | ||
| Development of Pancreatitis | 109 | ||
| Absorption of Digestion Products | 109 | ||
| Abnormalities in Protein Assimilation | 111 | ||
| LIPID ASSIMILATION | 112 | ||
| Digestion | 112 | ||
| Absorption of Lipolytic Products | 114 | ||
| Intracellular Events | 115 | ||
| Monoglyceride Acylation Pathway | 115 | ||
| Phosphatidic Acid Pathway | 115 | ||
| Abnormalities in Lipid Assimilation | 116 | ||
| VITAMINS | 117 | ||
| Abnormality in Vitamin Absorption | 118 | ||
| 12 - Fluid and Electrolyte Absorption | 121 | ||
| BIDIRECTIONAL FLUID FLUX | 121 | ||
| IONIC CONTENT OF LUMINAL FLUID | 121 | ||
| TRANSPORT ROUTES AND PROCESSES | 122 | ||
| Sodium-Chloride Transport | 122 | ||
| Potassium Transport | 124 | ||
| MECHANISM FOR WATER ABSORPTION AND SECRETION | 124 | ||
| INTESTINAL SECRETION | 125 | ||
| CALCIUM ABSORPTION | 126 | ||
| IRON ABSORPTION | 127 | ||
| 13 - Regulation of Food Intake | 131 | ||
| APPETITE CONTROL | 131 | ||
| THE NERVOUS SYSTEM | 132 | ||
| Hypothalamus | 132 | ||
| Enteric Nervous System and Vagus Nerve | 132 | ||
| THE ENDOCRINE SYSTEM | 132 | ||
| Insulin | 133 | ||
| Leptin | 133 | ||
| THE GASTROINTESTINAL SYSTEM | 133 | ||
| Cholecystokinin | 134 | ||
| Peptide YY | 134 | ||
| Ghrelin | 134 | ||
| Additional Peptides | 134 | ||
| A - ANSWERS TO SELF-STUDY PROBLEMS | 137 | ||
| CHAPTER 1 | 137 | ||
| CHAPTER 2 | 137 | ||
| CHAPTER 3 | 137 | ||
| CHAPTER 4 | 137 | ||
| CHAPTER 5 | 138 | ||
| CHAPTER 6 | 138 | ||
| CHAPTER 7 | 138 | ||
| CHAPTER 8 | 138 | ||
| CHAPTER 9 | 139 | ||
| CHAPTER 10 | 139 | ||
| CHAPTER 11 | 139 | ||
| CHAPTER 12 | 139 | ||
| CHAPTER 13 | 140 | ||
| B - Comprehensive Multiple-ChoiceReview Examination | 141 | ||
| INDEX | 148 | ||
| A | 148 | ||
| B | 148 | ||
| C | 149 | ||
| D | 149 | ||
| E | 150 | ||
| F | 150 | ||
| G | 150 | ||
| H | 151 | ||
| I | 151 | ||
| J | 151 | ||
| K | 151 | ||
| L | 152 | ||
| M | 152 | ||
| N | 152 | ||
| O | 152 | ||
| P | 153 | ||
| R | 153 | ||
| S | 153 | ||
| T | 154 | ||
| U | 154 | ||
| V | 154 | ||
| W | 155 | ||
| Z | 155 |