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Exotic Animal Neurology, An Issue of Veterinary Clinics of North America: Exotic Animal Practice, E-Book

Exotic Animal Neurology, An Issue of Veterinary Clinics of North America: Exotic Animal Practice, E-Book

Susan E. Orosz

(2017)

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Book Details

Abstract

This issue of Veterinary Clinics of North America: Exotic Animal Practice on Exotic Animal Neurology, edited by Susan Orosz, includes: Pain and its control in Reptiles; The Neuroanatomical basis for pain and controlling pain in birds; Avian Bornavirus and its pathophysiology for Proventricular dilatation disease; Treatment of Proventricular dilatation disease and avian ganglioneuritis; Vaccination for Proventricular dilatation disease; Imaging the brain for exotic animal clinicians; EC in rabbits; Pain control in small mammals; Vaccination of ferrets for Rabies and Distemper; and Medication for Behavior Modification in Birds.

Table of Contents

Section Title Page Action Price
Front Cover Cover
Exotic Animal Neurology i
Copyright\r ii
Contributors iii
CONSULTING EDITOR iii
EDITOR iii
AUTHORS iii
Contents v
Preface v
Pain and Its Control in Reptiles v
Pain in Birds: The Anatomical and Physiological Basis v
Avian Ganglioneuritis in Clinical Practice v
Clinical Signs, Diagnosis, and Treatment of Encephalitozoon cuniculi Infection in Rabbits v
Analgesics in Small Mammals vi
Vaccination of Ferrets for Rabies and Distemper vi
Medication for Behavior Modification in Birds vi
Functional and Anatomic Correlates of Neural Aging in Birds vi
Gut Brain Axis and Its Microbiota Regulation in Mammals and Birds vii
VETERINARY CLINICS OF\rNORTH AMERICA: EXOTIC\rANIMAL PRACTICE\r viii
FORTHCOMING ISSUES viii
May 2018 viii
September 2018 viii
January 2019 viii
RECENT ISSUES viii
September 2017 viii
May 2017 viii
January 2017 viii
Preface ix
Pain and Its Control in Reptiles 1
Key points 1
INTRODUCTION 1
NEUROANATOMY AND NEUROPHYSIOLOGY 2
Transduction 2
Transmission 2
Projection 2
Perception 3
REPTILE ANALGESICS 4
Local Analgesics 4
Spinal Analgesia 5
Systemic Analgesics 5
Anti-inflammatories 5
Opioids 8
Other analgesics 10
α2-ADRENERGIC AGONISTS 10
NMDA RECEPTOR ANTAGONIST 11
ALTERNATIVE MEDICINE 12
PREEMPTIVE AND MULTIMODAL ANALGESIA 12
SUMMARY 12
REFERENCES 13
Pain in Birds 17
Key points 17
INTRODUCTION 17
PERIPHERAL NERVOUS SYSTEM 18
CENTRAL NERVOUS SYSTEM 19
PERIPHERAL AND CENTRAL SENSITIZATION 25
REFERENCES 26
Avian Ganglioneuritis in Clinical Practice 33
Key points 33
INTRODUCTION 33
AVIAN GANGLIONEURITIS 34
Clinical Signs 34
Signs Associated with the Nervous System 34
PATHOLOGY 39
PATHOGENESIS 46
Avian Bornavirus 46
Infection Rate 47
Transmission 47
Incubation Period 48
Role of Avian Bornavirus in Pathogenesis of Avian Ganglioneuritis/Proventricular Dilatation Disease 49
Asymptomatic Infection with Avian Bornavirus 49
Proposed Autoimmune Mechanisms for Avian Ganglioneuritis/Proventricular Dilatation Disease 50
The Complement System and Its Proposed Role in Pathogenesis of Lesions 51
Lesion Characterization in Parrots and Ganglioside Sensitization of the Host 53
Diagnosis 56
Differential Diagnoses 57
Avian Bornavirus Diagnostics 57
Polymerase chain reaction 57
Serology 57
Treatment 58
Medications 58
Avian bornaviral vaccination 59
FORMULARY 60
REFERENCES 60
Clinical Signs, Diagnosis, and Treatment of Encephalitozoon cuniculi Infection in Rabbits 69
Key points 69
INTRODUCTION/BIOLOGY OF ENCEPHALITOZOON CUNICULI 69
Classification and Cell Structure 69
Life Cycle and Pathogenesis 70
Encephalitozoon cuniculi in Other Mammals and Humans 71
CLINICAL SIGNS 72
Neurologic Manifestation 72
Phacoclastic Uveitis 73
Clinical Signs Compatible with Chronic Interstitial Nephritis 73
DIAGNOSTIC WORKUP 73
Serologic Testing for Specific Immunoglobulin G and Immunoglobulin M Antibodies Against Encephalitozoon cuniculi 73
Polymerase Chain Reaction 75
Other Diagnostic Methods for Exclusion of Relevant Differential Diagnoses 76
TREATMENT OF RABBITS WITH VESTIBULAR DYSFUNCTION 76
Inhibition of Spore Proliferation 77
Anti-Inflammatory Therapy 77
Supportive Care 78
Physiotherapy: Therapeutic Exercise 78
REFERENCES 79
Analgesics in Small Mammals 83
Key points 83
INTRODUCTION 83
GENERAL SIGNS OF PAIN 84
SPECIFIC SIGNS OF PAIN 85
RODENT AND RABBIT GRIMACE SCALES (PAIN FACES) 87
ASSESSING PAIN IN CLINICAL PRACTICE 89
PAIN PREVENTION AND ALLEVIATION 90
Postoperative and Posttrauma Pain 90
Analgesic Agents 92
Nonsteroidal anti-inflammatory drugs 92
Acetaminophen (Paracetamol) 94
Opioids 94
Tramadol 95
Local anesthetics 96
Preventive Analgesia 96
Outpatient Analgesia 97
Recommendations 97
Managing Other Causes of Pain 98
SUMMARY 98
REFERENCES 99
Vaccination of Ferrets for Rabies and Distemper 105
Key points 105
DISTEMPER 105
RABIES 108
VACCINE REACTIONS 109
RISK ASSESSMENT AND VACCINATION POLICY 110
Ideal Kit Wellness and Vaccine Schedule 111
Ideal Adult Ferret Wellness Vaccine Schedule 111
Protocol and Strategies for Ferrets that Develop a Vaccine Reaction 112
THE FERRET AND VACCINE DEVELOPMENT OF THE FUTURE 112
ACKNOWLEDGMENTS 112
REFERENCES 112
Medication for Behavior Modification in Birds 115
Key points 115
INTRODUCTION 115
BEHAVIOR PROBLEMS: WHEN TO PRESCRIBE AND WHEN NOT TO PRESCRIBE MEDICATION 116
DIAGNOSTIC WORK-UP ESSENTIALS — ESTABLISHING A (DIFFERENTIAL) DIAGNOSIS AND RATIONALE FOR THE USE OF BEHAVIOR MODIFICATION ... 120
History 121
Direct Behavioral Observations 122
Physical Examination and Ancillary Tests 122
CHOOSING THE APPROPRIATE DRUG — CONSIDERATIONS FOR DRUG SELECTION 122
PSYCHOACTIVE DRUG CLASSES AND THEIR MODE OF ACTION 124
Benzodiazepines 127
Azapirones 134
Tricyclic Antidepressants 134
Selective Serotonin Reuptake Inhibitors 135
Antipsychotics 136
Opioid Antagonists 136
HORMONE THERAPY FOR TREATMENT OF REPRODUCTIVE-RELATED BEHAVIORS 137
THERAPY FOR PAIN-RELATED BEHAVIORS 138
THERAPY FOR PRURITUS-ASSOCIATED BEHAVIORS 139
THERAPEUTIC OPTIONS IN CASES OF CONVULSIVE BEHAVIORS 139
MONITORING AND FOLLOW-UP 140
SUMMARY 142
REFERENCES 142
Functional and Anatomic Correlates of Neural Aging in Birds 151
Key points 151
INTRODUCTION 151
AN OVERVIEW OF AGING IN BIRDS 152
EVIDENCE OF NEURAL AND COGNITIVE AGING IN SHORT- AND LONG-LIVED BIRDS 153
Auditory and Visual System Aging 153
Cognitive Function and Aging 154
SUMMARY 154
REFERENCES 155
Gut Brain Axis and Its Microbiota Regulation in Mammals and Birds 159
Key points 159
INTESTINAL MICROBIOTA AND ITS FUNCTION 159
ASSESSMENT OF INTESTINAL MICROBIOTA 160
INTESTINAL MICROBIOTA OF MAMMALS 161
Humans, Mice, Dogs, Cats 161
Rabbits, Ferrets, and Hamsters 161
INTESTINAL MICROBIOTA OF PARROTS AND PSITTACINES 162
EXAMPLES OF GUT-BRAIN AXIS INTERACTIONS ACROSS ANIMAL MODELS 162
SUMMARY 164
REFERENCES 165