Menu Expand
Gunner Goggles Medicine E-Book

Gunner Goggles Medicine E-Book

Hao-Hua Wu | Leo Wang

(2018)

Additional Information

Book Details

Abstract

The Gunner Goggles Series is the first exam prep resource written by a high-scoring peer group of medical students, ensuring the most practical and efficient study guidance. It organizes topics around the USMLE and NBME content outlines for the required shelf exams and features state-of-the-art Augmented Reality (AR) mobile application to extend learning beyond the book. This innovative series features AR opportunities throughout the text for an integrated print-mobile experience that maximizes learning and test preparation. The Gunner Goggle function allows you to scan pages for integrated AR links, unlocking animations, visuals, and 3D models that clarify complex anatomy, conditions, and concepts in a remarkably effective and unique manner.

Gunner Goggles Series: Medicine is one of seven authoritative exam preparation guides that use cutting-edge AR technology to fully prepare you for the NBME clinical shelf exams, the USMLE Step 2 Clinical Knowledge (CK) exam, and successful clinical rotations.

  • Topics are organized around the USMLE and NBME content outlines for specific shelf exams, and information is presented in a highly templated, concise manner.
  • The Augmented Reality application allows you to efficiently study and learn using an integrated print-mobile approach. In addition to unlocking animations and other visuals, AR app access also includes additional content, links to provide feedback to the authors, community pages, and more.
  • All test topics are covered in just enough detail to help you hone in on key points you must know for exam success.
  • Unique! Every disease is described by its stem clues (buzzwords that appear in question stems) and prophylactic measures (PPx), mechanism (MoD), diagnostic tests (Dx) and treatment/management principles (Tx/Mgmt) – the four "Physician Tasks" that the NBME requires students to know about each disease.
  • You’ll also get real-world tips for your clinical rotations from your peers – information that won’t show up on the shelf exam but is ideal for maximum impact when on rounds (knowing the prognosis for a specific disease, for example).
  • Plus … effective study techniques, sample study schedules, tips and tricks to better retain information learned from review questions, and methods to self-generate mnemonics.
  • Edited, written, and crowdsourced by high-performing medical students and residents and reviewed by experts in the field to ensure accuracy, relevancy, and accessibility.

Titles in the Gunner Goggles series:

Family Medicine • Print ISBN: 978-0-323-51034-9 • e-Book ISBN: 978-0-323-52756-9

Medicine • Print ISBN: 978-0-323-51035-6 • e-Book ISBN: 978-0-323-52758-3

Neurology • Print ISBN: 978-0-323-51036-3 • e-Book ISBN: 978-0-323-52760-6

Ob-Gyn • Print ISBN: 978-0-323-51037-0 • e-Book ISBN: 978-0-323-52768-2

Pediatrics • Print ISBN: 978-0-323-51038-7 • e-Book ISBN: 978-0-323-52763-7

Psychiatry • Print ISBN: 978-0-323-51039-4 e-Book ISBN: 978-0-323-52765-1

Surgery • Print ISBN: 978-0-323-51040-0 • e-Book ISBN: 978-0-323-52767-5


Table of Contents

Section Title Page Action Price
Front Cover Cover
IFC ES1
Gunner Goggles i
GUNNER GOGGLES:Medicine iii
Copyright iv
Gunner Goggles Honors Shelf Review Series v
Contributors vi
Acknowledgments viii
Contents ix
1 - Introduction 1
I. The Gunner’s Guide to a Better Test Score 1
II. Augmented Reality: A New Paradigm for Shelf Exam Test Prep 2
Presentation 3
Evaluation 3
Community Engagement 4
Augmented Reality Frequently Asked Questions 4
III. Study Smart: Mnemonics and Gunner Study Tips 5
Understand the Organizing Principle 5
Create Effective Mnemonics 5
Devise a Study Schedule and Stick to It 7
Distinguish Rotation-Knowledge From Shelf-Knowledge 7
IV. Intro to the National Board of Medical Examiners Clinical Science Medicine Subject Exam 8
2 - General Principles for the Internal Medicine Shelf 11
Introduction 11
How to Read the Vital Signs and Metabolic Panel 11
Hyponatremia 13
Hypernatremia 14
Hypokalemia 15
Hyperkalemia 15
How to Read an Electrocardiography 16
How to Deal With Bacteria and Antibiotics 22
Methicillin-Resistant Staphylococcus aureus 24
Pseudomonas 24
Enterococcus 24
Bacteroides fragilis 24
Common Antibiotic Toxicities Tested on the Medicine Shelf 25
How to Read a Chest X-Ray 25
Biostatics and Epidemiology for the Medicine Shelf 27
Medical Ethics for the Medicine Shelf 31
Patient With Suicidal Ideation 31
Action 31
3 - Immunologic Disorders 49
Introduction 49
Disorders Associated With Immunodeficiency 50
Deficiency Primarily of Humoral Immunity 51
Common Variable Immunodeficiency 51
Hyper-IgM Syndrome 51
X-Linked Bruton (Agammaglobulinemia) 52
IgA Immunodeficiency 53
Deficiency/Dysfunction Primarily of Cell-Mediated Immunity 53
22q11.2 Deletion Syndrome (DiGeorge) 55
Severe Combined Immunodeficiency Disease 56
Wiskott-Aldrich Syndrome 57
Complement Deficiency 57
Terminal Complement Deficiency 58
C1 Esterase Inhibitor Deficiency (Acquired Angioedema) 58
Hereditary Angioedema 59
Deficiency of Phagocytic Cells and Natural Killer Cells 59
Chediak-Higashi Syndrome 59
Chronic Granulomatous Disease 60
Leukocyte Adhesion Deficiency 61
Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome 61
Human Immunodeficiency Virus Infection and Acquired Immunodeficiency Syndrome 61
Immunologically Mediated Disorders 63
Adverse Effects of Drugs on the Immune System 63
Jarisch-Herxheimer Reaction 65
Notes 67
4 - Diseases of the Blood and Blood-Forming Organs 71
Introduction 71
Infections of the Blood 71
Bacterial Infections of the Blood 71
Infections of Lymphoid Tissue 75
Lymphadenitis 75
Lymphangitis 76
Bubonic Plague (Yersinia pestis) 76
Cat Scratch Disease (Bartonella henselae) 77
Immunologic and Inflammatory Disorders 77
Cryoglobulinemia (Essential Mixed Cryoglobulinemia) 77
Autoimmune Hemolytic Anemia 78
Paroxysmal Nocturnal Hemoglobinuria 80
Thrombotic Thrombocytopenia Purpura 80
Hemolytic Uremic Syndrome 81
Neoplasms 81
Acute Lymphoblastic Leukemia 82
Acute Myelogenous Leukemia 82
Chronic Lymphocytic Leukemia/Small Lymphocytic Leukemia 83
Chronic Myelogenous Leukemia 84
Hodgkin Lymphoma 86
Non-Hodgkin Lymphoma 87
Burkitt Lymphoma 88
T-cell Lymphoma 88
Multiple Myeloma 89
Monoclonal Gammopathy of Unknown Significance 90
Myelofibrosis 91
Myelodysplastic Syndrome 92
Waldenstrom Macroglobulinemia (Lymphoplasmacytic Lymphoma) 92
Anemia 93
Microcytic Anemia 93
G6PD Deficiency 94
Pyruvate Kinase Deficiency 95
Hereditary Spherocytosis 96
Hereditary Elliptocytosis (Ovalocytosis) 97
Methemoglobinemia 97
Sickle Cell Disease 98
Sideroblastic Anemia 99
Thalassemias 101
Anemia from Blood Loss 102
Cytopenias 103
Aplastic Anemia 103
Leukopenia 103
Immune Thrombocytopenic Purpura 104
Polycythemias 104
Polycythemia Vera 104
Essential Thrombocythemia (Essential Thrombocytosis) 105
Coagulation Disorders 106
Hypocoagulable States 107
Disseminated Intravascular Coagulation 108
Hemophilia A 109
Hemophilia B 109
Hypofibrinogenemia/Afibrinogenemia (Factor I deficiency) 110
Von Willebrand Disease 110
Bernard-Soulier Syndrome (Hemorrhagiparous Thrombocytic Dystrophy) 111
Glanzmann Thrombasthenia 111
Hypercoagulable States 112
Heparin-Induced Thrombocytopenia/Thrombosis 113
Warfarin-Induced Skin Necrosis 113
Homocysteinemia 114
Hypoplasminogenemia 114
Antithrombin III Deficiency 115
Protein C/S Deficiency 115
Factor V Leiden 116
Antiphospholipid Syndrome (Lupus Anticoagulant, Anticardiolipin) 116
Prothrombin G20210A Mutation 117
Reactions to Blood Components 118
Traumatic, Mechanical, and Vascular Disorders 118
Cardiac Valve Hemolysis 118
Splenic Rupture/Laceration 118
Splenic Infarct 120
Splenic Abscess 120
Effects/Complications of Splenectomy 120
Hypersplenism 121
Adverse Effects of Drugs on the Hematologic and Lymphoreticular System 121
Notes 127
5 - Diseases of the Nervous System and Special Senses 132
General Principles for Diseases of the Nervous System and Special Senses 132
Infectious, Immunologic, and Inflammatory Disorders 133
Acute Bacterial Meningitis 133
Acute Viral Meningitis (Aseptic Meningitis) 135
Fungal Meningitis 136
Spirochetal Meningitis (Neurosyphilis) 137
Protozoal/Helminth Meningitis 138
Acute Encephalitis 139
Subacute Sclerosing Panencephalitis 139
Prion Disease 140
Opportunistic Central Nervous System Disorders Associated With Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome 141
Immunologic and Inflammatory Disorders 141
Myasthenia Gravis 142
Lambert Eaton Syndrome 143
Multiple Sclerosis 144
Internuclear Ophthalmoplegia 146
Optic Neuritis 146
Transverse Myelitis 147
Central Nervous System Neoplasms 147
Malignant 148
Glioblastoma Multiforme 148
Pilocytic Astrocytoma 148
Medulloblastoma 149
Primary Central Nervous System Lymphoma 150
Metastatic 150
Benign 150
Meningioma 150
Pituitary Adenoma 151
Cerebrovascular Disease 153
Cerebral Artery Occlusion/Infarction 153
Transient Ischemic Attack 156
Subarachnoid Hemorrhage (Non-Traumatic) 157
Major Artery Stenosis/Dissection 157
Carotid Artery Dissection 158
Subclavian Steal Syndrome 158
Vascular Dementia 158
Venous Sinus Thrombosis 159
Arterio-Venous Malformation 159
Disorders Relating to Spine, Spinal Cord, Spinal Nerve Roots 160
Cauda Equina Syndrome 160
Conus Medullaris Syndrome 160
Spinal Cord Compression 161
Spinal Stenosis (Lumbar) 162
Spinal Artery Thrombosis/Embolus/Infarct 162
Cranial and Peripheral Nerve Disorders 164
Cranial Nerve Injuries/Disorders 164
Facial Nerve Palsy (Peripheral Type) 164
Vestibular Neuritis (CN VIII Disease) 165
Peripheral Nerve/Plexus Disorders 166
Klumpke’s Palsy (Brachial Plexus Lower Trunk injury) 166
Thoracic Outlet Syndrome 167
Axillary Neuropathy 167
Musculocutaneous Neuropathy 167
Radial Neuropathy (“Saturday Night Palsy”) 167
Median Neuropathy 168
Carpal Tunnel 168
Guillain-Barré Syndrome (Acute Inflammatory Demyelinating Polyneuropathy) 170
Herpes Zoster (Shingles) 171
Neurologic Pain Syndromes 171
Trigeminal Neuralgia 171
Global Cerebral Dysfunction 173
Delirium (State of Acute Confusion) 173
Alzheimer Disease 173
Frontotemporal Dementia (aka Pick Disease) 174
Lewy Body Dementia 174
Amyotrophic Lateral Sclerosis and Muscle Diseases 175
Amyotrophic Lateral Sclerosis (Motor Neuron Disease) 175
Muscular Dystrophy (Duchenne Versus Becker) 176
Movement Disorders 176
Acute Dystonia 177
Essential Tremor 177
Huntington Disease 178
Parkinson Disease 179
Headache 179
Migraine 180
Tension 180
Cluster 181
Epilepsy 181
Generalized Clonic-Tonic Seizure 181
Partial Seizures 182
Sleep Disorders 183
Cataplexy and Narcolepsy 183
Insomnia 184
Sleep Terrors 184
Rapid Eye Movement Sleep Behavior Disorders 184
Restless Leg Syndrome 185
Traumatic and Mechanical Disorders of Increased Intracranial Pressure 185
Elevated Intracranial Pressure 186
Epidural Hematoma 186
Subdural Hematoma 186
Intraparenchymal Hemorrhage 187
TBI (Contusion, Concussion, Post-Concussion Syndrome) 188
Idiopathic Intracranial Hypertension (Pseudotumor Cerebri) 189
Normal Pressure Hydrocephalus 189
Congenital/Genetic Disorders 190
Friedreich Ataxia 191
Neural Tube Defects 192
Sturge-Weber 192
Tuberous Sclerosis 192
Von Hippel Lindau syndrome 193
Neurofibromatosis I (Von Recklinghausen Disease) 194
Adverse Effects of Drugs on the Nervous System 195
Drug-Induced Meningitis 195
Drug-Induced Neuropathy 195
Extrapyramidal Adverse Effects 196
Neuroleptic Malignant Syndrome 196
Notes 199
6 - Cardiovascular Disease 204
Introduction 204
The Heart and Great Vessels 204
Ischemic Heart Disease 205
Stable Angina 205
Unstable Angina 206
Non-ST-Elevation Myocardial Infarction 206
ST-Elevation Myocardial Infarction 207
Prinzmetal Angina (Variant Angina) 209
Arrhythmias 209
Premature Atrial Contractions/Premature Ventricular Contractions 209
Atrial Arrhythmia 210
Atrial Fibrillation 210
Atrial Flutter 211
Multifocal Atrial Tachycardia 212
Reentrant Tachycardia 213
Ventricular Arrhythmia 213
Ventricular Tachycardia 213
Ventricular Fibrillation 214
Conduction Blocks 215
1st Degree Heart Block 215
2nd Degree Heart Block 216
3rd Degree (Complete) Heart Block 217
Bundle Branch Blocks 217
Long-QT Syndromes 219
Sick Sinus Syndrome 219
Wolf-Parkinson-White Syndrome 220
Heart Failure 221
Congestive Heart Failure 221
Systolic Dysfunction (heart failure with reduced ejection fraction/HFrEF) 221
High-Output Cardiac Failure 222
Valvular Heart Disease 223
Aortic Valve Disease 223
Aortic Stenosis 223
Aortic Regurgitation 224
Mitral Valve Disease 225
Mitral Stenosis 225
Mitral Valve Prolapse 225
Mitral Regurgitation 226
Tricuspid Valve Disease 226
Tricuspid Stenosis 226
Tricuspid Regurgitation 227
Pulmonic Valve Disease 227
Pulmonic Stenosis 227
Pulmonic Regurgitation 228
Pericardial Disease 228
Pericardial Effusion 228
Pericarditis 230
Acute 230
Constrictive 231
Endocarditis and Myocarditis 231
Endocarditis 231
Infectious 231
Non-Infectious (marantic endocarditis) 233
Myocarditis 233
Cardiac Trauma 234
Myocardial Contusion 234
Myocardial Free Wall Rupture 234
Traumatic Aortic Rupture 235
Congenital Cardiac Malformations 235
Endocardial Cushion Defects 235
Ventricular Septal Defect 235
Atrial Septal Defect 237
Patent Foramen Ovale 237
Patent Ductus Arteriosus 237
Tetralogy of Fallot (Fig. 6.23) 237
Transposition of the Great Vessels (Fig. 6.25) 238
Total Anomalous Pulmonary Venous Return 239
Truncus Arteriosus 239
Tricuspid Atresia 241
Cardiac Neoplasms 241
Atrial Myxoma 241
Hypertension and Hypotension 241
Hypotension 241
Orthostatic Hypotension 241
Carotid Sinus Hypersensitivity 242
Hypertension 242
Hypertensive Urgency 243
Hypertensive Emergency 243
Vascular Disease 245
Arterial Disease 245
Peripheral Artery Disease 245
Thromboangiitis Obliterans (Buerger Disease) 245
Embolic Disease 245
Compartment Syndrome 246
Venous Disease 246
Deep Vein Thrombosis 246
Venous Insufficiency 247
Disorders of the Great Vessels 248
Aortic Aneurysm 248
Aortic Dissection 248
Dyslipidemia 250
Familial Hypercholesterolemia 250
Familial Hyperchylomicronemia (Lipoprotein Lipase Deficiency) 251
Familial Hypertriglyceridemia 251
Medication Side Effects Involving the Heart 252
Cardiotoxic Drugs 252
Cocaine—May Cause Coronary Artery Vasospasm and Typical ACS Chest Pain, Diaphoresis, HTN 252
QT-prolonging Medications 252
Anti-hypertensives 252
7 - Diseases of the Respiratory System 258
Introduction 258
Disorders of the Lung Parenchyma 258
Alpha-1 Antitrypsin Deficiency 258
Cystic Fibrosis 259
Acute Nasopharyngitis (“The Common Cold”) 261
Influenza (“The Flu”) 261
Sinusitis 262
Epiglottitis 263
Croup (Laryngotracheobronchitis) 264
Acute Laryngitis 265
Bacterial Tracheitis 265
Streptococcal pharyngitis 265
Peritonsillar Abscess 266
Allergic Rhinitis 266
Infectious, Immunologic, and Inflammatory Disorders of the Lower Airway 267
Pneumonia 267
Cryptogenic Organizing Pneumonia (formerly bronchiolitis obliterans organizing pneumonia) 268
Anthrax 269
Bordetella pertussis (Whooping Cough) 270
Aspiration Pneumonia/Lung Abscess 270
Fungal Infections 271
Allergic Bronchopulmonary Aspergillosis 271
Histoplasmosis 271
Coccidioidomycosis 272
Blastomycosis 273
Pneumocystis Pneumonia 273
Obstructive Airway Disease 274
Asthma 274
Acute Asthma Management 275
Long-Term Asthma Management 275
Chronic Obstructive Pulmonary Disease 276
Pneumoconioses 277
Hypersensitivity Pneumonitis 277
Interstitial Lung Disease/Idiopathic Pulmonary Fibrosis 277
Benign Neoplasms of Upper Airways 279
Vocal Cord Polyps 279
Nasal Polyps 279
Benign Neoplasms of Lung and Pleura 280
Solitary Pulmonary Nodule 280
Bronchial Carcinoid Tumor 281
Malignant Neoplasms of Upper Airways 281
Lip—Squamous Cell Carcinoma (SCC) 281
Oral Cavity—Squamous Cell Carcinoma 283
Pharynx—Squamous Cell Carcinoma 283
Larynx—Squamous Cell Carcinoma 283
Malignant Neoplasms of Lower Airway 283
Squamous Cell Carcinoma 283
Adenocarcinoma 285
Large Cell Carcinoma 285
Small Cell Carcinoma 286
Malignant Neoplasms of Pleura 287
Mesothelioma 287
Metastasis to Lung 288
Respiratory Failure/Respiratory Arrest and Pulmonary Vascular Disorders 288
Acute Respiratory Distress Syndrome 288
Pulmonary Hypertension 289
Pulmonary Arteriovenous Malformations (PAVMs) 290
Noncardiogenic Pulmonary Edema 291
Cardiogenic Pulmonary Edema 291
Pulmonary Embolism 292
Air Embolism 293
Fat Embolism 294
Respiratory Failure Due to Enteral Feeding 294
Disorders of the Pleura, Mediastinum, and Chest Wall 295
Pleural Effusion 295
Chylothorax 296
Empyema 296
Mediastinitis 297
Pleuritis 298
Spontaneous Pneumothorax 298
Costochondritis 299
Traumatic and Mechanical Disorders of Upper Airways 299
Epistaxis 299
Barotrauma 300
Laryngeal/Pharyngeal Obstruction 300
Tracheal Stenosis 301
Tracheomalacia 301
Blunt Tracheal Injury 302
Penetrating Neck/Tracheal Injury 303
Foreign Body Aspiration (Pharynx, Larynx, and Trachea) 303
Septal Perforation 304
Traumatic Disorders of Lower Airways and Pleura 304
Atelectasis 304
Blunt Chest Wall and Diaphragm Injury 305
Penetrating Chest Wound 306
Traumatic Pneumothorax/Tension Pneumothorax 307
Hemothorax 308
Pulmonary Contusion 308
Pneumomediastinum 308
Foreign Body Aspiration (Bronchi and Lungs) 309
Upper and Lower Respiratory Tract 309
Obstructive Sleep Apnea 309
Central Sleep Apnea 310
Obesity-Hypoventilation Syndrome 311
Congenital Disorders 311
Bronchogenic Cysts 311
Congenital Diaphragmatic Hernia 312
Pulmonary Sequestration 312
Immotile Cilia Syndrome/Primary Ciliary Dyskinesia 313
Tracheoesophageal Fistula 314
8 - Nutritional and Digestive Disorders 322
General Signs and Symptoms 323
Dysphagia 323
Paralytic Ileus 323
Impaction 324
Intestinal Obstruction/Stricture 324
Fecal Incontinence 325
Proctitis 325
Ascites 326
Ischemic Hepatitis 327
Jaundice 327
Infectious Disorders 328
Bacterial 328
Pseudomembranous Colitis (Clostridium difficile) 328
Enteric Infections 328
Staphylococcus aureus 328
Escherichia coli 329
Listeria monocytogenes 330
Yersinia enterocolitica 331
Campylobacter spp 331
Vibrio cholera 332
Salmonella spp 332
Shigella spp 333
Hepatic Abscess 333
Pyogenic 333
Amebic Abscess 334
Echinococcus 334
Peritonitis 335
Primary Peritonitis 335
Secondary Peritonitis 336
Whipple Disease 336
Viral Infections of the Gastrointestinal Tract 337
Infectious Esophagitis 337
Hepatitis A 337
Hepatitis B 338
Hepatitis C 338
Hepatitis D 339
Hepatitis E 340
Rotavirus Enteritis 340
Mumps 340
Gingivostomatitis, Herpetic 341
Fungal 341
Thrush 341
Parasitic 342
Cryptosporidium 342
Cyclospora 342
Entamoeba histolytica 343
Giardia 343
Cystoisospora (isospora) belli 344
Strongyloides stercoralis 344
Immunologic and Inflammatory Disorders 345
Autoimmune Hepatitis 345
Celiac Disease 345
Eosinophilic Esophagitis 346
Inflammatory Bowel Disease 346
Crohn Disease 348
Ulcerative Colitis 348
Microscopic Colitis 349
Toxic Megacolon 349
Neoplasms 350
Benign Neoplasms 350
Polyps 350
Gastric Polyps 350
Small and Large Bowel Polyps 350
Oral Leukoplakia 351
Oral Cancer 351
Squamous Cell Carcinoma 351
Salivary Gland Neoplasm 351
Barrett Esophagus 352
Esophageal Cancer 352
Squamous Cell Carcinoma 352
Adenocarcinoma 353
Gastrinoma and Zollinger-Ellison Syndrome 353
Carcinoid Tumors 354
Gastrointestinal Stromal Tumors 354
Stomach 355
Adenocarcinoma 355
Gastric Lymphoma 356
Colon, Rectum, Anus 357
Hereditary Colon Cancer Syndromes 357
Familial Adenomatous Polyposis 357
Hereditary Nonpolyposis Colon Cancer (Lynch Syndrome) 357
Peutz-Jeghers Syndrome (PJS) 358
Gardner Syndrome 359
MUTYH-Associated Polyposis 359
Biliary Tract 360
Gallbladder Adenocarcinoma 360
Cholangiocarcinoma 360
Adenocarcinoma of the Ampulla of Vater 360
Liver 361
Cavernous Hemangioma 361
Focal Nodular Hyperplasia 361
Hepatic Adenoma 362
Hepatocellular Carcinoma 362
Peritoneal Cancer 363
Pancreas 363
Exocrine Pancreas, Pancreatic Carcinoma 363
Signs, Symptoms and Ill-Defined Disorders 365
Upper Gastrointestinal Bleeding 365
Lower Gastrointestinal Bleeding 366
Constipation 366
Diarrhea 366
Nausea and Vomiting 367
Disorders of the Salivary Gland and Esophagus 368
Disorders of the Salivary Glands 368
Stones 368
Sialadenitis 368
Suppurative Parotitis 368
Esophagus 369
Achalasia 369
Zenker Diverticulum 370
Esophagitis/Esophageal Reflux 370
Esophagitis, Pill 371
Mallory-Weiss Syndrome 371
Paraesophageal (Hiatal) Hernia 371
Diffuse Esophageal Spasm 372
Disorders of the Stomach, Small Intestine, Colon, Rectum, Anus 373
Stomach 373
Peptic Ulcer Disease 373
Peptic Ulcer Perforation 374
Small Intestine and Colon 375
Appendicitis 375
Angiodysplasia 375
Diverticulosis and Diverticulitis 376
Hirschsprung Disease 377
Irritable Colon/Irritable Bowel Syndrome 377
Ischemic Bowel 378
Malnutrition 378
Malabsorption 379
Dumping Syndrome 380
Lactose Intolerance 380
Short Bowel Syndrome 380
Rectum and Anus 381
Abscess of Anal and Rectal Regions 381
Anorectal Fistula 382
Anal Fissure 382
Hemorrhoids 383
Rectal Prolapse 384
Disorders of the Liver and Biliary System, Noninfectious 384
Liver 384
Cirrhosis 384
Dubin-Johnson Syndrome 385
Rotor Syndrome 386
Gilbert Syndrome 386
Crigler-Najjar Syndrome 387
End-Stage Liver Disease (Including Indications for Transplantation) 387
Hepatic Coma/Encephalopathy 388
Fatty Liver, Alcoholic Hepatitis 389
Hepatorenal Syndrome 389
Hepatopulmonary Syndrome 390
Jaundice 391
Nonalcoholic Fatty Liver Disease 391
Portal Hypertension/Esophageal Varices 392
Biliary System 393
Cholestasis 393
Ascending Cholangitis 394
Cholelithiasis and Acute Cholecystitis 394
Choledocholithiasis 395
Cholestasis Due to Parenteral Nutrition 396
Gallstone Ileus 396
Mirizzi Syndrome 396
Primary Biliary Cirrhosis 397
Primary Sclerosing Cholangitis 397
Disorders of the Pancreas 398
Acute Pancreatitis 398
Chronic Pancreatitis 399
Hereditary Pancreatitis 400
Pancreatic Cyst/Pseudocyst 401
Pancreatic Insufficiency 401
Traumatic and Mechanical Disorders 401
Postgastric Surgery Syndromes 401
Blind Loop Syndrome 401
Adhesions 402
Hernias 402
Direct Inguinal Hernia 402
Indirect Inguinal Hernia 403
Femoral Hernia 403
Umbilical Hernia 403
Penetrating Wounds, Abdominal 404
Perforation of Hollow Viscus and Blunt Abdominal Trauma 404
Perforation/Rupture of Esophagus (Boerhaave Syndrome) 405
Congenital Disorders 405
Intussusception 405
Necrotizing Enterocolitis 406
Volvulus 407
Annular Pancreas 407
Biliary Atresia 408
Cleft Lip and Palate 408
Esophageal Atresia 409
Malrotation Without Volvulus 409
Meckel Diverticulum 410
Pyloric Stenosis 410
Gastric Outlet Obstruction 411
Tracheoesophageal fistula 411
Wilson Disease 412
Adverse Drug Effects 413
Drug-Induced Changes in Motility 413
Chronic Laxative Abuse 413
Opioids 413
Drug-Induced Gastritis, Duodenitis, and Peptic Ulcer 413
Drug-Induced Hepatitis 414
Drug-Induced Pancreatitis (e.g., Thiazides) 414
Notes 417
9 - Gynecologic Disorders 421
Introduction 421
Menopause 421
Gynecologic Neoplasms 422
Fibroadenoma 422
Intraductal Papilloma 423
Breast Cancer 423
Paget Disease of the Breast 424
Ovarian Cancer 426
Sexually Transmitted Infections 427
Herpes Simplex Virus 427
Neisseria Gonorrhea 429
Chlamydia Trachomatis 429
Fitz-Hugh-Curtis Syndrome 430
Pelvic Inflammatory Disease (Acute Salpingitis) 430
Tubo-ovarian Abscess (TOA) 431
Syphilis 432
Granuloma Inguinale 433
Lymphogranuloma Venereum 434
Chancroid 434
Trichomoniasis 435
Bacterial Vaginosis (BV) 435
Multisystem Processes 436
Polycystic Ovarian Syndrome (PCOS, Stein-Leventhal Syndrome) 436
Endometriosis 437
Ectopic Pregnancy 438
Notes 441
10 - Renal, Urinary, and Male Reproductive System 445
Introduction 445
Organizing Principles and Key Terms 445
Acute Kidney Injury/Acute Renal Failure 445
Prerenal Renal Failure 446
Intrinsic Renal Failure 446
Postrenal Acute Renal Failure 447
Chronic Kidney Disease/Chronic Renal Failure 447
Dialysis 448
Hematuria 449
Proteinuria 449
Nephritic Versus Nephrotic Syndrome 450
The Upper Urinary Tract 450
Infectious Disorders of the Upper Urinary Tract 457
Pyelonephritis 457
Xanthogranulomatous Pyelonephritis 457
Perinephric and Renal Abscess 458
Renal Tuberculosis 458
Renal Stones 458
Neoplastic Disorders and Cysts of the Upper Renal Tract 460
Simple Renal Cyst 460
Autosomal Dominant Polycystic Kidney Disease 460
Autosomal Recessive Polycystic Kidney Disease 461
Medullary Sponge Kidney Disease 461
Renal Cell Carcinoma 462
Wilms Tumor/Nephroblastoma 462
Vascular Pathology Affecting the Upper Urinary Tract 462
Renal Infarction 463
The Lower Urinary Tract 464
Cystitis 464
Chlamydial Urethritis 465
Inflammatory Processes 466
Interstitial Cystitis/Hemorrhagic Cystitis 466
Neoplasms of the Lower Urinary Tract 467
Bladder Cancer 467
Prostate Cancer 467
Testicular Cancer 468
Penile Cancer 469
Double Collecting System, Double Ureter, Bifid Ureter 470
Horseshoe Kidney 470
Klinefelter Syndrome 471
Hypospadias/Epispadias 471
Genitourinary Trauma and Mechanical Disorders 472
Kidney, Bladder, or Urethral Trauma 472
Penile Fracture 473
Testicular Rupture/Avulsion/Hematocele 473
Peyronie Disease 473
Sexual Dysfunction 474
Impotence/Erectile Dysfunction 474
Premature Ejaculation 474
Dyspareunia 475
Arousal Disorder 475
Adverse Effects of Drugs on the Renal, Urinary, and Male Reproductive System 475
Notes 479
11 - Disorders of the Skin and Subcutaneous Tissues 482
Diseases 482
Infections and Infestations 482
Bacterial 482
Cellulitis 482
Erysipelas 483
Impetigo 483
Skin Abscesses, Furuncles, and Carbuncles 485
Folliculitis 485
Pilonidal Disease 487
Cutaneous Anthrax Infection 487
Cutaneous Mycobacterial Infection 487
Viral 487
Herpes Simplex Virus Types 1 and 2 487
Varicella-Zoster Virus 489
Molluscum Contagiosum 491
Hand-Foot-and-Mouth Disease 492
Parvovirus B19 492
Rubella 494
Rubeola 495
Verrucae Vulgaris 495
Fungal 496
Candidiasis 496
Tinea (Pedis, Cruris, Corporis, Capitis) and Onychomycosis 497
Tinea Versicolor 498
Sporotrichosis 499
Parasitic 500
Cutaneous Larva Migrans 500
Cutaneous Leishmaniasis 500
Infestations and Bites 501
Scabies 501
Lice 502
Arthropod Bites and Bed Bugs 502
Inflammatory and Immunologic Disorders 503
Psoriasis 503
Lichenoid Disorders 503
Lichen Planus 503
Lichen Sclerosis 504
Lichen Simplex Chronicus 505
Pityriasis Rosea 505
Dermatitis 506
Atopic Dermatitis (Eczema) 506
Allergic and Irritant Contact Dermatitis 506
Urticaria 507
Erythema Multiforme 507
Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis 508
Dermatitis Herpetiformis 508
Pyoderma Gangrenosum 509
Erythema Nodosum 509
Pemphigus Vulgaris, Foliaceus, and Bullous Pemphigoid 510
Vitiligo 510
Neoplasms 511
Benign Neoplasms 511
Actinic Keratosis 511
Seborrheic Keratosis 511
Nevus 511
Epidermoid Cyst 512
Lipoma 513
Xanthoma 513
Malignant Neoplasms 513
Basal Cell Carcinoma 513
Squamous Cell Carcinoma 513
Melanoma 514
Kaposi Sarcoma 515
Cutaneous T-cell Lymphoma 515
Other Disorders 516
Disorders of the Hair 516
Alopecia 516
Seborrheic Dermatitis 516
Disorders of the Nails 517
Paronychia 517
Ingrown Nail 517
Disorders of Sweat and Sebaceous Glands 517
Acne Vulgaris 517
Rosacea 518
Hidradenitis Suppurativa 518
Hyperhidrosis 519
Ichthyosis Vulgaris 519
Oral Disease 519
Aphthous Ulcers 519
Leukoplakia 520
Disorders of Pigmentation 520
Albinism 520
Lentigo 520
Traumatic, Mechanical, and Latrogenic Disorders 521
Animal Bites 521
Burns 521
Pernio and Frostbite 522
Pressure Ulcers 522
Keloids and Hypertrophic Scars 522
Drug and Vaccine Eruptions 523
Notes 525
12 - Diseases of the Musculoskeletal System and Connective Tissue 529
Introduction 529
Infectious Disorders 529
Gangrene 529
Discitis (Vertebral Osteomyelitis) 530
Infective Myositis 531
Necrotizing Fasciitis 531
Osteomyelitis 532
Septic Arthritis 532
Immunologic Disorders 533
Adhesive Capsulitis (Frozen Shoulder Syndrome) 533
Ankylosing Spondylitis 533
Bursitis 534
Osteochondritis Dissecans 535
Tendinitis 535
Temporomandibular Joint Disorders 536
Autoimmune Myositis Polymyositis/Dermatomyositis 536
Benign Neoplasms 537
Osteochondroma 537
Giant Cell Tumor 538
Malignant Neoplasms 538
Osteosarcoma 538
Ewing Sarcoma 539
Cancer Metastases to Bone 539
Degenerative and Metabolic Disorders of Bone, Tendon, and Cartilage 539
Chondromalacia Patellae (Patellofemoral Pain Syndrome) 539
Herniated Disc 540
Legg-Calve-Perthes Disease 541
Osgood-Schlatter Disease 542
Osteodystrophy 542
Osteomalacia/Rickets 543
Avascular Necrosis of Femoral Head 543
Osteopenia/Osteoporosis 544
Osteitis Deformans (Paget Disease of Bone) 544
Spondylolisthesis 545
Degenerative and Metabolic Disorders of Joints 545
Gout 545
Pseudogout (Calcium Pyrophosphate Dihydrate Deposition Disease) 546
Osteoarthritis 547
Degenerative and Metabolic Disorders of Muscles, Ligaments, and Fascia 547
Dupuytren Contracture 547
Myositis Ossificans 548
Rhabdomyolysis 548
Traumatic and Mechanical Disorders 549
Kyphoscoliosis 549
Rotator Cuff Tear 549
Slipped Capital Femoral Epiphysis 550
Congenital Disorders 550
Developmental Dysplasia of the Hip 550
Genu Valgum (Knock-Knee) and Genu Varum (Bow-Leg) 551
Foot Deformities 551
Osteogenesis Imperfecta (“Brittle Bone Disease”) 552
McArdle Disease (Glycogen Storage Disease V) 552
Mitochondrial Myopathies 553
Adverse Defects of Drugs on the MSK System 553
Drug-induced Myopathy 553
Malignant Hyperthermia 554
13 - Endocrine and Metabolic Disorders 559
Introduction 559
Diabetes and the Endocrine Pancreas 560
Diabetes 560
Diabetes Mellitus Type 1 560
Diabetes Mellitus Type 2 561
Chronic Complications of Diabetes Mellitus 563
Hypoglycemia and Islet Cell Disorders 564
Hyperglycemia (Glucagonoma) 564
Thyroid Disorders 565
Thyroid Nodule 565
Euthyroid Sick Syndrome 565
Hypothyroidism 566
Hashimoto Thyroiditis 567
Subacute (Viral) Thyroiditis 567
Myxedema Coma 567
Hyperthyroidism 567
Graves Disease 568
Thyroid Storm 569
Thyrotoxicosis 569
Neoplasms 570
Thyroid Deficiency from Pituitary Disorder (Refer to Pituitary Section) 570
Secondary Hypothyroidism and Hyperthyroidism 570
Parathyroid Disorders 570
Hyperparathyroidism 570
Hypoparathyroidism 572
Metabolic Bone Disease 572
Adrenal Disorders 573
Addison Disease 573
Secondary Adrenal Insufficiency 574
Cushing Syndrome 574
Cushing Disease 576
Hyperaldosteronism 576
Pheochromocytoma 577
Endocrine Diseases Which Cause Hypertension 577
Pituitary Disorders 577
Pituitary Adenomas 577
Acromegaly/Gigantism 578
Diabetes Insipidus 579
Panhypopituitarism 579
Pituitary Apoplexy (Sheehan Syndrome) 580
Growth Hormone Deficiency 580
SIADH 580
Prolactinoma and Hyperprolactinemia 581
Craniopharyngiomas 581
Hypogonadism, Primary and Secondary 582
Multiple Endocrine Neoplasia (MEN1, MEN2) 583
Notes 585
14 - Gunner Jim’s Guide to Exam Day Success 588
“Master One Review Book” 588
“Do as Many Quality Questions as You Can” 589
“Review Questions in Excel” 589
Index 591
A 591
B 593
C 595
D 598
E 599
F 600
G 601
H 602
I 604
J 606
K 606
L 606
M 608
N 610
O 612
P 613
Q 615
R 615
S 616
T 618
U 619
V 620
W 620
X 621
Y 621
Z 621
How to Contribute to Gunner Goggles Medicine ES2