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Shaw's Textbook of Gynecology-EBOOK

Shaw's Textbook of Gynecology-EBOOK

Sunesh kumar | V. G. Padubidri | Shirish N Daftary

(2018)

Additional Information

Book Details

Abstract

  • Extensively revised and updated to incorporate the latest changes and development of newer concept.
  • Written in a narrative manner which is easier to understand.
  • Bulleted text and key highlights/ important points in boxes for extra emphasis and retention.
  • Inclusion of more flowcharts and colored pictures.
  • Covers the entire course curriculum in an easy to understand, retain and reproducible manner; including assessment questions to help in rapid revision and exam preparation.
  • 13 videos to help for better understanding.
  • 6 Lecture notes on challenging topics.

This book has a seamless narration with bulleted key points, important highlights in boxes, well-illustrated text and self-assessment questions.

It is an enhanced book with videos and lecture notes on challenging procedures to help them better visualize, understand, and retain information


Table of Contents

Section Title Page Action Price
Front cover Cover
Front matter i
Howkins & bourne shaw’s textbook of gynaecology 17th edition iii
Copyright iv
Dedication v
Preface to the 17th edition vi
Preface to the 16th edition vii
Preface to the 10th edition viii
Table of Content ix
1 Approach to a gynaecological patient 1
History 1
Present illness 1
Past and personal history 1
Family history 2
Marital and sexual history 2
Menstrual history 2
Obstetric history 3
Physical examination 3
General examination 3
Systemic examination 3
Abdominal examination 3
Inspection 3
Palpation 4
Percussion 4
Auscultation 4
Gynaecological examination 4
Examination of external genitalia 4
Speculum examination 4
Bimanual examination 4
Rectal examination 6
Investigations 6
Special tests 7
Hanging drop preparation 7
Papanicolaou test 7
Screening for cancer 7
Visual inspection after acetic acid application (via) 8
Schiller test (visual inspection after lugol’s iodine application – vili) 8
Cytohormonal evaluation 10
Uterine aspiration cytology 10
Colposcopy 10
Endometrial biopsy (fig. 1.14a and b) 10
Hormonal assays 11
Ultrasonography 11
Other imaging modalities 11
Gynaecological endoscopy 11
Pregnancy test 11
Self-assessment 11
Suggested reading 11
SECTION 1 ANATOMY, PHYSIOLOGY AND DEVELOPMENT OF FEMALE REPRODUCTIVE ORGANS 12
2 Anatomy of female genital tract 13
The vulva 13
Labia majora 13
Labia minora 13
Bartholin’s gland 15
The vagina 15
Relations of vagina 16
Anterior relation 16
Posterior relations 17
Lateral relations 17
Superior relations 17
The uterus 18
Peritoneal covering 18
Myometrium 18
Endometrium 18
Position of the uterus 20
The uterine appendages 21
Fallopian tubes 21
The ovaries 23
The urethra 23
Relations 23
The bladder 24
Nerve supply 24
The ureters 24
The rectum and anal canal 25
The lymphatics 25
The pelvic musculature 25
Pelvic diaphragm 25
Urogenital diaphragm 26
Superficial muscles 26
The pelvic cellular tissue 28
The pelvic blood vessels 29
The vaginal arteries 31
The arteries of the vulva and perineum 31
The pelvic veins 31
The lymphatic system 31
The lymphatic glands or nodes 31
The inguinal glands 32
The glands of the parametrium 32
External iliac glands 32
Common iliac glands 32
The sacral group 32
The lumbar group of glands 32
The nerve supply 33
Applied anatomy and its clinical significance 33
Self-assessment 35
Suggested reading 36
3 Normal histology of ovary and endometrium 37
The ovary 37
The primordial follicle 37
The graafian follicle (fig. 3.2) 37
The fate of the graafian follicle 39
Ovulation 39
Corpus luteum (fig. 3.7a and b) 40
Menstruation 41
Corpus luteum of pregnancy 41
The endometrium 41
The proliferative phase 41
The secretory phase 42
The menstruating endometrium 43
Endometrial regeneration 44
Functional layers of endometrium 45
The decidua of pregnancy 45
Ectopic decidual cells 45
Vaginal epithelium 45
Ovarian functions 45
Pregnancy 46
Menopausal endometrium 46
Cervical mucus 46
Process of fertilization 46
Self-assessment 47
Suggested reading 47
4 Physiology of ovulation and menstruation 48
Hypothalamic–pituitary–ovarian axis 48
Hypothalamus 48
Pituitary gland 50
Anterior pituitary gland (adenohypophysis) 50
Follicle-stimulating hormone 50
Luteinizing hormone 50
Human chorionic gonadotropin 51
Prolactin 51
Posterior pituitary gland (neurohypophysis) 51
Oxytocin 51
Vasopressin 51
Ovarian steroidogenesis 51
Oestrogen 51
Actions of oestrogens (fig. 4.4) 52
Progesterone 53
Actions of progesterones 53
Side effects 53
Relaxin 54
Inhibin 54
Activin 54
Anti-müllerian hormone 54
Sex hormone–binding proteins 54
Testosterone 54
Physiology of menstruation 54
Feedback mechanism in the H–P–O axis 56
Leptin 58
Menstruation 58
Menstrual fluid in ‘stem cell’ therapy 60
Self-assessment 60
Suggested reading 60
5 Development of female reproductive organs and related disorders 61
Development of the female genital organs 61
Development of urinary system 61
Development of the uterus, cervix and vagina 61
Development of vagina 63
Development of the external genital organs (figs 5.6 and 5.7) 63
Development of the ovaries 64
Gonads 65
Müllerian ducts 66
Detailed consideration of müllerian defects 67
Introduction 67
Defining features 68
Characteristic features 68
Differential diagnosis 69
Investigations 69
Management 69
Complete nonfusion of the müllerian ducts results in duplication of the genital tract 70
Detailed consideration of relevant anomalies of the müllerian ducts 70
Classification 70
Prevalence 72
Background 72
Diagnosis 72
Adverse obstetric outcomes 72
Surgical resection of the intrauterine septum (metroplasty) 72
Malformations of the rectum and anal canal 73
Imperforate anus 73
Atresia recti 73
Congenital rectovaginal fistula 73
Wolffian duct anomalies 73
Renal tract abnormalities 73
Self-assessment 74
Suggested reading 74
6 Puberty, adolescence and related gynaecological problems 75
Introduction 75
Reproductive endocrinology of the growing girl child 75
The newborn female infant 76
The growing girl child 76
Common paediatric gynaecologic problems 77
Puberty and adolescence 79
Biological sequential events observed during puberty 79
Factors affecting time of onset of puberty 80
Physical growth and body weight 80
Secondary sex characters (ssc) – tanner classification of the sequence of development 80
Thelarche 80
Adrenarche 80
Pubic hair development 80
Axillary hair development 82
Genital organs 82
Menarche 82
Skeletal age 82
Management 82
Puberty – anomalies of gonadal function 82
Treatment of delayed puberty 83
Adolescent contraception 84
Miscellaneous problems 85
Self-assessment 85
Suggested reading 85
7 Menopause and related problems 86
Introduction 86
Perimenopause (climacteric) 86
Diagnosis of approaching menopause 86
Menopause 86
Demography 87
Age 87
Pathophysiology 87
Hormone levels 87
Anatomical changes 87
Menopausal symptoms (table 7.2) 88
Menstrual 88
Hot flushes 88
Other symptoms 88
Neurological 88
Libido 89
Urinary tract 89
Genital 89
Neurological 89
Late effects of menopause 89
Osteoporosis (fig. 7.2) 89
Pathophysiology. 89
Cardiovascular diseases 90
Stroke 90
Skin 90
Alzheimer disease 90
Endocrine system 90
Pyometra 90
Approach to a menopausal woman 90
Management 90
Counselling 90
Mild tranquillizers 90
Hormone replacement therapy 91
Who needs HRT? 91
Uses of HRT 91
Osteoporosis 91
Prophylaxis of osteoporosis 91
Cardioprotective effect of HRT 91
Drugs, dosage and route of administration 92
Oestrogen therapy 92
Long-term therapy. 92
Oral route. 92
Transdermal patch (estraderm). 92
Vaginal cream. 92
Vaginal ring. 92
Implant. 92
Progestogens 93
Other drugs 93
Suggestions for HRT 94
Hormone replacement therapy and risk of breast cancer 94
Hormone replacement therapy and endometrial carcinoma 94
Premature menopause (premature ovarian failure) 94
Aetiology 95
Pathophysiology 95
Clinical features 95
Investigations 95
Complications 95
Management 95
Late menopause 95
Postmenopausal bleeding 96
Cause of postmenopausal bleeding 96
Clinical features 96
History 96
Examination 96
Investigations 96
Management 97
Self-assessment 98
Suggested reading 98
8 Breast and gynaecologist 99
Congenital deformities 99
Benign tumours 100
Breast cancer 102
Self-assessment 105
Suggested reading 105
9 Sexual development and disorders of sexual development 106
Principles of sexual development (fig. 9.1) 106
Summary of sex organs development 106
Gonads 106
Internal genitalia 108
External genitalia 108
Facets of sexual differentiation 108
Classification of intersex disorder 108
Gender identity disorders associated with normal sex chromosome constitutions 108
Gender identity disorders associated with abnormal sex chromosome constitutions 109
Factors influencing designation of sex 109
Genetic sex 109
External anatomical sex 110
Internal anatomical sex 110
Gonadal sex 110
Hormonal influences 110
Psychological sex 110
Environment and upbringing 110
Clinical diagnosis of sex 111
External appearance 111
External genitalia 111
Internal genitalia 112
Signs of feminism in the male 112
External appearance 112
External genitalia 112
Clinical examples 112
Disorders of female sexual differentiation 112
Swyer syndrome 112
Turner syndrome 112
Superfemale (triple X chromosome) 113
Male pseudohermaphrodite 113
Aetiology 113
Management 113
Partial androgen insensitivity syndrome 114
Enzyme errors in androgen production 114
Masculinization 114
Klinefelter syndrome 114
Virilism 114
Clinical features 114
Clinical varieties 114
Adrenogenital syndrome 114
Congenital or intrauterine adrenogenital syndrome 114
Postnatal adrenogenital syndrome 115
Virilizing tumours and other conditions of the ovary 116
Treatment 116
Female pseudohermaphroditism 116
Investigations and management of an intersexual patient 116
Hirsutism 116
Endocrinology 116
Causes of hirsutism 117
Clinical features 117
Investigations 118
History 118
Examination 118
Hormonal study 118
Ultrasound scan 118
Management 118
Acne 120
True hermaphrodite 120
Psychological sex 120
Self-assessment 120
Suggested reading 120
SECTION 2 DISORDERS OF MENSTRUATION 121
10 Common disorders of menstruation 122
Menstrual cycle irregularities 122
Various types of menstrual cycle irregularities 122
Heavy menstrual bleeding (HMB) 122
Oligomenorrhoea and hypomenorrhoea 123
Oligomenorrhoea 123
Hypomenorrhoea 123
Polymenorrhoea or epimenorrhoea 123
Metrorrhagia 123
Dysmenorrhoea 124
Definition 124
Aetiology 124
Types 124
Varieties 124
Aetiology of pain (fig. 10.1) 124
Clinical features (table 10.2) 124
Investigations 125
Treatment 125
Medical measures 125
Surgery 125
Premenstrual syndrome 126
Aetiology 126
Clinical features 126
Diagnosis 126
Treatment (table 10.4) 126
Self-assessment 127
Suggested reading 127
11 Abnormal uterine bleeding (AUB) 128
Introduction 128
Normal control of menstrual bleeding 128
Causes of abnormal uterine bleeding (table 11.1) 128
General diseases causing heavy menses 130
Local pelvic causes 130
Intrauterine contraceptive device 131
Investigations 131
Management 131
SECTION 3 COMMON CONDITIONS IN GYNAECOLOGY 201
16 Infertility male and female 202
Physiology of fertilization 202
Infertility 203
Issues involved 203
Initial counselling 203
Male infertility 203
Development and growth in a male 203
Spermatogenesis 203
Structure of the sperm (fig. 16.2) 204
Endocrine control 204
Endocrine control of spermatogenesis 205
Fertilization 205
Male factor infertility 205
Faults in the male 205
Aetiological classification 205
Investigations 206
Semen analysis 206
Postcoital test (sims’ or huhner’s test, PCT) 207
Sperm penetration test 207
Semen–cervical mucous contact test 207
Management of male infertility 208
Hormonal therapies for male infertility 209
Management of azoospermia 210
LVF 210
Psychological considerations 211
Female infertility 212
Aetiology 212
Vaginismus 212
Treatment 213
Dyspareunia 213
Investigations 214
Treatment 214
Work up of female partner 215
History 216
Examination 216
Tests for tubal patency 216
Hysterosalpingography 216
Laparoscopic chromotubation 218
Sonosalpingography (SSG) 218
Newer modalities of tubal tests 218
Management of tubal infertility 219
Tests of ovulation 220
Basal body temperature 220
Endometrial biopsy 220
Fern test 220
Ultrasound follicular monitoring 221
Hormonal assays 221
Plasma progesterone 221
LH 222
Hyperprolactinaemia 222
FSH 222
Thyroid tests 222
Management of anovulation 222
Clomiphene citrate 222
Letrozole 222
Combination of CC + hMG 222
GnRH 223
Prednisolone 223
Hyperprolactinaemia 223
Laparoscopic ovarian drilling 223
Complications of ovulation induction 223
Ovarian hyperstimulation syndrome 223
Pathogenesis 223
Complications 224
Prevention 224
Treatment 224
Investigation and monitoring 224
Peritoneal factors 224
Endometriosis 224
Luteinized unruptured follicular syndrome 224
Unexplained infertility 224
Assisted reproductive technology: An overview 225
Definition 225
Indications 225
Investigations prior to art 225
Types of art procedures in current practice 225
Self-assessment 226
Suggested reading 226
17 Ectopic gestation 228
Types of ectopic gestation 228
Epidemiology 228
Incidence 228
Aetiology (table 17.1) 229
Aetiopathogenesis 229
Pathology 230
Tubal pregnancy 230
Ovarian pregnancy 230
Abdominal pregnancy 232
Primary abdominal pregnancy 232
Secondary abdominal pregnancy 232
Interstitial pregnancy 232
Pregnancy in an accessory horn of uterus (cornual pregnancy) (fig. 17.11) 232
Co-existing intrauterine pregnancy and ectopic pregnancy (heterotopic pregnancy) 233
Symptoms, signs and diagnosis 233
Symptoms 233
Amenorrhoea 233
Pain 233
Vaginal bleeding 233
Acute retention of urine 233
Fever 234
Physical signs 234
Acute ectopic pregnancy 234
Differential diagnosis 234
Subacute and chronic variety of ectopic pregnancy 235
Differential diagnosis of chronic ectopic pregnancy 235
Pyosalpinx 235
Septic abortion 235
Pelvic abscess 235
Twisted ovarian cyst 235
Rupture of a chocolate cyst 235
Uterine fibroid 235
Corpus luteal haematoma 235
Acute appendicitis 236
Diagnostic investigations (table 17.3) 236
Urinary/serum hCG 236
β-hCG 236
Ultrasound 236
Culdocentesis or aspiration of the pouch of douglas 237
Other hormonal studies 237
Laparoscopy 237
Treatment 237
Medical management 237
Methotrexate therapy 237
Side effects of methotrexate 238
Contraindications 238
Other surgically administered medical (sam) drugs 238
Postmedication management 239
Surgical treatment 239
Types of surgery on the fallopian tube 239
Conservative tubal surgery 240
Interstitial pregnancy 240
Treatment 240
Prognosis 240
Unruptured ectopic gestation 240
Expectant treatment (fig. 17.21) 241
Ovarian pregnancy 241
Cervical pregnancy 242
Ultrasound 242
Treatment of cervical pregnancy 242
Cornual pregnancy 242
Heterotopic pregnancy 243
SECTION 4 BENIGN CONDITIONS IN GYNAECOLOGY 285
21 Genital prolapse 286
Supports of the uterus 286
Aetiology of prolapse uterus (table 21.1) 287
Classification of prolapse (figs 21.3 and 21.4) 287
Cystocele 287
Prolapse of the uterus 290
Prolapse of the posterior vaginal wall 290
Decubitus ulcer 290
Elongation of the cervix 291
Obstruction of the urinary tract 291
Pop-q system (table 21.2, fig. 21.3) 291
Symptoms of prolapse 291
Investigations 292
Differential diagnosis 292
Complications of pelvic organ prolapse 292
Prevention of prolapse 292
Treatment (table 21.3) 293
Pessary treatment of prolapse 293
Operative treatment of prolapse 293
Preoperative preparation 293
Surgery 293
Anterior colporrhaphy 294
Posterior colporrhaphy and colpoperineorrhaphy 294
Fothergill’s repair (manchester operation) 294
Shirodkar’s procedure 295
Vaginal hysterectomy with pelvic floor repair 295
The steps of vaginal hysterectomy (figs 21.15–21.18) 295
Alternative methods of tying pedicles during surgery 295
Ligasure.  295
Le fort’s repair 297
Abdominal sling operations 297
Abdominal wall cervicopexy 297
Shirodkar’s abdominal sling operation for uterine prolapse 298
Khanna’s sling operation 298
Enterocele 298
Vault prolapse 298
Degrees of vault prolapse 298
Prevention 298
Treatment (table 21.4) 298
Vaginal sacrospinous colpopexy 299
Postoperative care 300
Recurrent prolapse and prosthetics 300
Self-assessment 301
Suggested reading 301
22 Displacements of the uterus 302
Introduction 302
Retroversion 302
Aetiology 302
Mobile retroversion 302
Fixed retroversion 303
Symptoms 303
Dysmenorrhoea 303
Menorrhagia 303
Pressure 303
Backache 303
Dyspareunia 303
Infertility 303
Abortion 303
Retroverted gravid uterus causing retention of urine 303
Diagnosis 303
Treatment 303
Pessary treatment 304
Surgery 304
Indications 304
Ventrosuspension 304
Plication of round ligaments 304
Baldy–webster operation 304
Inversion of the uterus 304
Acute inversion 304
Prevention 305
Treatment 305
Chronic inversion 305
Degrees of inversion (fig. 22.6) 306
Treatment 306
Self-assessment 306
Suggested reading 307
23 Diseases of the broad ligament, fallopian tubes and parametrium 308
Diseases of broad ligament 308
Broad ligament cysts 308
Anatomical considerations 308
Paraovarian cysts 308
Treatment 309
Tumours of the fallopian tubes 309
Conditions affecting the broad ligament and parametrium 309
Haematoma 309
Parametritis 309
Tumours of the broad ligament and parametrium 310
Myoma 310
Sarcoma 310
Lipoma 310
Retroperitoneal tumours 310
Self-assessment 311
Suggested reading 311
24 Benign diseases of the ovary 312
Nonneoplastic enlargements of the ovary (table 24.1) 312
Functional cysts in ovary 312
Follicular cysts 312
Follicular haematomas (follicular cyst with haemorrhage) 313
Lutein cysts of the ovary 313
Corpus luteum (granulosa lutein) cysts 313
Theca lutein cysts 313
Multiple functional cysts 313
Pituitary adenoma 313
Ovarian hyperstimulation syndrome 314
Polycystic ovarian syndrome 314
Polycystic ovarian syndrome or disease PCO, PCOS, PCOD 314
Incidence 314
Aetiology and pathogenesis 314
Ovarian steroidogenesis in PCOS 314
Pathology 315
Clinical features (table 24.2) 315
Examination of a girl with PCOS 315
Diagnostic criteria for making a diagnosis of PCOS 315
Differential diagnosis 316
Investigations 316
Treatment 316
Surgery 317
Prevention 317
Self-assessment 318
Suggested reading 318
25 Benign diseases of the vulva 319
Introduction 319
Benign diseases of the vulva 319
Inflammatory lesions 319
Skin infections 319
Intertrigo and folliculitis 319
Tinea cruris 319
Threadworms 320
Vulvovaginitis 320
Bartholin’s abscess 320
Psoriasis 320
Filariasis 320
Contact vulvitis 320
Pruritus vulva 320
Causes of pruritus vulvae 320
Treatment 321
Ulcers 321
Clinical features 321
Behcet disease 321
Atrophy 322
Vulval pain syndrome 322
Vestibulitis 322
Dysaesthetic vulvodynia 322
Management 322
Vulval dystrophies 322
Hyperplastic dystrophy (squamous cell hyperplasia), previously known as leukoplakia 322
Lichen sclerosus (atrophic dystrophy) 323
Cysts and neoplasms 325
Vulval cysts 325
Sebaceous cyst 325
Bartholin’s cyst 325
Cyst of the canal of nuck 325
Vulval neoplasms 325
Fibroma and lipoma 325
Hidradenoma 325
Pigmented mole or naevi 325
Endometriosis 325
Elephantiasis of vulva (fig. 25.8) 325
Self-assessment 325
Suggested reading 325
26 Benign diseases of the vagina 326
Biology of the vagina 326
Structure of vaginal epithelium 327
Physiological changes in the vaginal epithelium 327
Cytology of the vagina 328
Vaginal acidity 328
Natural defence mechanism of the vagina 328
Flora of the female genital tract 328
Leucorrhoea 329
Excessive cervical secretions (cervical leucorrhoea) 329
Excessive vaginal secretions (nonpathogenic vaginal leucorrhoea) 329
Pathological vaginal infections 329
Vaginitis 329
Candidal vaginitis 330
Trichomonas vaginitis 330
Vaginosis (bacterial) 330
Miscellaneous causes of excessive vaginal discharge 332
Inflammation of the vagina 332
Aetiology 332
Symptoms and signs 332
Diagnosis 332
Treatment 332
General 332
Local 332
Oestrogen deficiency–related vaginitis 333
Vulvovaginitis in children 333
SECTION 5 INFECTIONS IN GYNAECOLOGY 336
27 Pelvic inflammatory disease 337
Pelvic inflammatory disease 337
Aetiology 337
Pathological anatomy 339
Acute salpingitis 339
Chronic PID 339
Hydrosalpinx (figs 27.6 and 27.7) 340
Chronic pyosalpinx (figs 27.4 and 27.5) 340
Chronic interstitial salpingitis 341
Tubo-ovarian cyst 341
Tuberculous form 341
Staging 341
Symptoms and signs of PID 341
Acute pelvic infection 341
Differential diagnosis 341
Acute appendicitis 341
Ectopic gestation 342
Diverticulitis 342
A twisted ovarian cyst 342
Ruptured endometriotic cyst 342
Septic abortion 342
Cholecystitis 342
Investigations 342
Chronic pelvic inflammatory disease 343
Treatment 343
Treatment of acute PID 343
Surgical treatment 344
Minimal invasive surgery 345
Surgical treatment of chronic PID 345
Prognosis 345
End results 345
Prevention of PID (table 27.5) 345
Rare variety of PID due to actinomyces 346
Self-assessment 346
Suggested reading 346
28 Tuberculosis of the female genital tract 347
Introduction 347
Pathogenesis 347
Genital tract lesions 348
Clinical features of genital tuberculosis 350
Investigations 351
Differential diagnosis 352
Treatment 353
Chemotherapy 353
Place of surgery in treatment of female genital tuberculosis 354
Types of surgery 354
Follow-up 354
Prognosis 354
In vitro fertilization (IVF) 354
Self-assessment 354
Suggested reading 354
29 Sexually transmitted diseases including HIV infection 356
Vulvar infections 356
Parasitic infection (pediculosis pubis) 356
Clinical features 356
Diagnosis 356
Treatment 356
Scabies 357
SECTION 6 URINARY AND INTESTINAL TRACT IN GYNAECOLOGY 371
30 Diseases of the urinary tract 372
Common urinary symptoms 372
Acute retention of urine (table 30.1) 372
Causes 372
Postoperative retention 372
Puerperal retention of urine 373
Obstructive conditions 373
Space-occupying lesions in the pelvis 373
Neurological causes 373
Chronic retention with overflow 373
Treatment of urinary retention 373
Urethral syndrome 373
Difficult micturition 373
Painful micturition 374
Increased frequency of micturition 374
Incontinence of urine 374
Cystitis 375
Symptoms 375
Diagnosis 375
Treatment 375
Chronic cystitis 375
Pyelonephritis (pyelitis) 376
SECTION 7 GYNAECOLOGICAL MALIGNANCIES 407
33 Preinvasive and invasive carcinoma of cervix 408
Epidemiology (table 33.1) 408
Squamocolumnar junction 409
Original squamocolumnar junction 409
New squamocolumnar junction 409
The transformation zone 409
Cervical intraepithelial neoplasia (CIN) 409
Dysplasia (figs 33.2–33.9) 409
Diagnosis 411
Cytological screening for cancer cervix 411
Other screening techniques 412
Colposcopy 412
Cervicography 413
Cone biopsy 414
HPV testing 414
Treatment of cervical dysplasias and CIN (table 33.4; figs 33.13 –33.19) 414
Cryosurgery 418
Mechanism of action 418
Electrocoagulation 418
Laser ablation 418
Excisional and cone biopsy 418
Punch biopsy 418
Large loop excision of the transformation zone (LLETZ/LEEP) 418
Conization 419
Hysterectomy 419
Follow-up after treatment of HSIL 419
Glandular lesions of cervix 419
Prevention of cancer of the cervix 420
Prophylactic HPV vaccines 420
Reported side effects of vaccine 420
HPV vaccine for males 420
Invasive cancer of the cervix 420
Pathology 420
Histological classification 420
Mode of spread 421
Clinical features 421
Differential diagnosis 422
Staging of cancer of the cervix (figs 33.27–33.39; table 33.6) 422
Incidence of lymph node metastasis in cancer cervix 422
Para-aortic lymph node metastasis 424
Diagnosis 424
Investigations 425
Treatment of invasive cancer 426
Surgical treatment 426
Stagewise treatment of cancer of the cervix 426
Complications of radical hysterectomy 427
Radiotherapy 427
Indications for postoperative radiotherapy 427
Recurrence of cancer 427
Recurrent lesion 428
Follow-up of a treated case of cancer of the cervix 428
Management of recurrences 428
Stagewise treatment of cancer of the cervix 428
Conservative surgery in a young woman 429
Carcinoma in pregnancy 429
Endocervical adenocarcinoma of cervix 430
Results 430
Prognosis 430
Stump cancer 430
Palliative treatment in terminal stages of cancer of the cervix 430
Future development 430
Self-assessment 431
Suggested reading 431
34 Cancer of the body of the uterus 432
Endometrial cancer 432
Predisposing factors (table 34.1) 433
Pathology (fig. 34.6) 434
Modes of spread 434
Tumour differentiation 434
Types of endometrial cancers 434
Clinical features 434
Investigations 435
Differential diagnosis 436
Endometrial hyperplasia 436
2014 revised who classification of endometrial hyperplasia 436
SECTION 8 IMAGING MODALITIES, ENDOSCOPIC PROCEDURES AND MAJOR AND MINOR OPERATIONS IN GYNAECOLOGY 506
40 Imaging modalities in gynaecology 507
Plain radiography 507
Hysterosalpingography 507
Technique 507
Contraindications 509
Complications 509
Advantages 509
Sonosalpingography 509
Intravenous urography 509
Indications 509
Precautions and contraindications 510
Cystography and urethrography 510
Gastrointestinal imaging studies 510
Barium meal and follow through 510
Barium enema 510
Arteriography and arterial embolization 510
Ultrasonography (figs 40.6–40.16) 511
Normal ultrasonic findings 513
Diagnostic indications 514
Interventional ultrasound in gynaecology 514
Computed tomography scan 515
Technique 516
Index 553
A 553
B 553
C 554
D 555
E 555
F 555
G 556
H 556
I 557
J 557
K 557
L 558
M 558
N 559
O 559
P 559
Q 560
R 560
S 560
T 561
U 561
V 562
W 562
X 562
Y 562
Z 562